Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03295:Xlr3c'

416066

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Xlr3c

Ensembl Gene

ENSMUSG00000058147

Gene Name

X-linked lymphocyte-regulated 3C

Synonyms

Xlr3b

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL03295

Quality Score

Status

Chromosome

Chromosomal Location

72298146-72308996 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

A to T at 72301240 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000079651 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000080839] [ENSMUST00000179600]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000080839

SMART Domains

Protein: ENSMUSP00000079651
Gene: ENSMUSG00000058147

Domain	Start	End	E-Value	Type
Pfam:Cor1	75	200	1e-33	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000179600

SMART Domains

Protein: ENSMUSP00000137006
Gene: ENSMUSG00000058328

Domain	Start	End	E-Value	Type
low complexity region	42	53	N/A	INTRINSIC
Pfam:Cor1	76	204	7.4e-24	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A930011G23Rik	A	T	5: 99,390,915 (GRCm39)		probably benign	Het
Adamts5	T	C	16: 85,674,833 (GRCm39)	T444A	probably damaging	Het
Aldh18a1	T	C	19: 40,551,386 (GRCm39)	E522G	probably damaging	Het
Bbx	T	C	16: 50,044,927 (GRCm39)	T437A	probably damaging	Het
Bsx	A	G	9: 40,785,743 (GRCm39)		probably benign	Het
Cdc42bpa	A	G	1: 179,977,769 (GRCm39)	N729S	probably benign	Het
Cdk1	G	T	10: 69,178,373 (GRCm39)	H162Q	possibly damaging	Het
Chrac1	A	G	15: 72,965,445 (GRCm39)		probably benign	Het
Cip2a	T	C	16: 48,814,704 (GRCm39)	S22P	probably damaging	Het
Ddx60	A	T	8: 62,409,155 (GRCm39)	D397V	possibly damaging	Het
Edn2	T	A	4: 120,019,178 (GRCm39)	C56S	probably damaging	Het
Gm4952	T	C	19: 12,595,691 (GRCm39)	V27A	probably benign	Het
Herc1	T	A	9: 66,303,985 (GRCm39)	S763T	possibly damaging	Het
Hspd1	G	A	1: 55,119,334 (GRCm39)	T381I	probably benign	Het
Krt1c	T	A	15: 101,724,864 (GRCm39)	I249F	probably damaging	Het
Lman2l	T	C	1: 36,477,892 (GRCm39)	D148G	probably damaging	Het
Lrp1b	C	T	2: 40,568,999 (GRCm39)		probably null	Het
Mier3	C	A	13: 111,840,215 (GRCm39)	T51K	probably benign	Het
Ppp1r36	C	T	12: 76,485,192 (GRCm39)	P305L	probably damaging	Het
Pramel27	G	A	4: 143,579,759 (GRCm39)	C448Y	probably damaging	Het
Prdm1	T	C	10: 44,315,866 (GRCm39)	I790V	probably damaging	Het
Sephs2	T	C	7: 126,871,941 (GRCm39)	E384G	possibly damaging	Het
Sipa1l1	T	A	12: 82,479,714 (GRCm39)	W1466R	probably damaging	Het
Snai2	T	C	16: 14,524,638 (GRCm39)	L48P	possibly damaging	Het
Stt3a	A	G	9: 36,674,627 (GRCm39)		probably null	Het
Synj1	T	A	16: 90,735,318 (GRCm39)	N1545I	probably benign	Het
Vav2	A	T	2: 27,165,041 (GRCm39)	S607T	possibly damaging	Het
Wdr27	T	C	17: 15,154,837 (GRCm39)	K27E	possibly damaging	Het
Xcl1	A	T	1: 164,763,004 (GRCm39)	V19E	unknown	Het
Zbtb44	T	A	9: 30,964,753 (GRCm39)	D54E	probably benign	Het
Zscan21	A	G	5: 138,123,540 (GRCm39)	D73G	possibly damaging	Het

Other mutations in Xlr3c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01335:Xlr3c	APN	X	72,303,639 (GRCm39)	missense	probably benign	0.03
Z1177:Xlr3c	UTSW	X	72,307,002 (GRCm39)	missense	possibly damaging	0.91

Posted On

2016-08-02