Incidental Mutation 'IGL03295:Bsx'
ID416069
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Bsx
Ensembl Gene ENSMUSG00000054360
Gene Namebrain specific homeobox
SynonymsBsx1a, Bsx1b
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL03295
Quality Score
Status
Chromosome9
Chromosomal Location40874127-40880057 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 40874447 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000068057 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000067375]
Predicted Effect probably benign
Transcript: ENSMUST00000067375
SMART Domains Protein: ENSMUSP00000068057
Gene: ENSMUSG00000054360

DomainStartEndE-ValueType
low complexity region 57 81 N/A INTRINSIC
HOX 110 172 2.64e-26 SMART
Coding Region Coverage
Validation Efficiency
MGI Phenotype PHENOTYPE: Mice homozygous for mutations in Bsx display increased fat mass, decreased food intake after fasting, decreased body temperature, and reduced locomotor activity, but body weight and glucose homoeostasis are similar to wild-type. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
A930011G23Rik A T 5: 99,243,056 probably benign Het
Adamts5 T C 16: 85,877,945 T444A probably damaging Het
Aldh18a1 T C 19: 40,562,942 E522G probably damaging Het
Bbx T C 16: 50,224,564 T437A probably damaging Het
C330027C09Rik T C 16: 48,994,341 S22P probably damaging Het
Cdc42bpa A G 1: 180,150,204 N729S probably benign Het
Cdk1 G T 10: 69,342,543 H162Q possibly damaging Het
Chrac1 A G 15: 73,093,596 probably benign Het
Ddx60 A T 8: 61,956,121 D397V possibly damaging Het
Edn2 T A 4: 120,161,981 C56S probably damaging Het
Gm13103 G A 4: 143,853,189 C448Y probably damaging Het
Gm4952 T C 19: 12,618,327 V27A probably benign Het
Herc1 T A 9: 66,396,703 S763T possibly damaging Het
Hspd1 G A 1: 55,080,175 T381I probably benign Het
Krt2 T A 15: 101,816,429 I249F probably damaging Het
Lman2l T C 1: 36,438,811 D148G probably damaging Het
Lrp1b C T 2: 40,678,987 probably null Het
Mier3 C A 13: 111,703,681 T51K probably benign Het
Ppp1r36 C T 12: 76,438,418 P305L probably damaging Het
Prdm1 T C 10: 44,439,870 I790V probably damaging Het
Sephs2 T C 7: 127,272,769 E384G possibly damaging Het
Sipa1l1 T A 12: 82,432,940 W1466R probably damaging Het
Snai2 T C 16: 14,706,774 L48P possibly damaging Het
Stt3a A G 9: 36,763,331 probably null Het
Synj1 T A 16: 90,938,430 N1545I probably benign Het
Vav2 A T 2: 27,275,029 S607T possibly damaging Het
Wdr27 T C 17: 14,934,575 K27E possibly damaging Het
Xcl1 A T 1: 164,935,435 V19E unknown Het
Xlr3c A T X: 73,257,634 probably null Het
Zbtb44 T A 9: 31,053,457 D54E probably benign Het
Zscan21 A G 5: 138,125,278 D73G possibly damaging Het
Other mutations in Bsx
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02318:Bsx APN 9 40874221 missense probably benign 0.00
IGL02510:Bsx APN 9 40874221 missense possibly damaging 0.49
R0507:Bsx UTSW 9 40876500 splice site probably benign
R0686:Bsx UTSW 9 40876437 missense probably damaging 1.00
R3120:Bsx UTSW 9 40877612 missense possibly damaging 0.95
R4155:Bsx UTSW 9 40876336 missense probably benign 0.04
R5504:Bsx UTSW 9 40874164 start gained probably benign
R6328:Bsx UTSW 9 40874223 missense probably damaging 1.00
X0027:Bsx UTSW 9 40877773 missense probably benign
Posted On2016-08-02