Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03299:Mxra7'

416190

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Mxra7

Ensembl Gene

ENSMUSG00000020814

Gene Name

matrix-remodelling associated 7

Synonyms

1810057P16Rik, E130302J09Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL03299

Quality Score

Status

Chromosome

Chromosomal Location

116694226-116718953 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

A to G at 116695360 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000134412 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000021170] [ENSMUST00000047715] [ENSMUST00000150015]

AlphaFold

Q9CZH7

Predicted Effect

probably benign
Transcript: ENSMUST00000021170

SMART Domains

Protein: ENSMUSP00000021170
Gene: ENSMUSG00000020814

Domain	Start	End	E-Value	Type
signal peptide	1	32	N/A	INTRINSIC
low complexity region	44	68	N/A	INTRINSIC
low complexity region	74	87	N/A	INTRINSIC
low complexity region	100	108	N/A	INTRINSIC
low complexity region	134	139	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000047715

SMART Domains

Protein: ENSMUSP00000038213
Gene: ENSMUSG00000020814

Domain	Start	End	E-Value	Type
signal peptide	1	32	N/A	INTRINSIC
low complexity region	44	68	N/A	INTRINSIC
low complexity region	74	87	N/A	INTRINSIC
low complexity region	100	108	N/A	INTRINSIC
low complexity region	134	139	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000150015

SMART Domains

Protein: ENSMUSP00000134412
Gene: ENSMUSG00000020814

Domain	Start	End	E-Value	Type
signal peptide	1	32	N/A	INTRINSIC
low complexity region	44	68	N/A	INTRINSIC
low complexity region	74	87	N/A	INTRINSIC
low complexity region	100	108	N/A	INTRINSIC
low complexity region	134	139	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921511C20Rik	A	G	X: 126,303,476 (GRCm39)		probably benign	Het
Abca17	A	T	17: 24,484,565 (GRCm39)	C1566S	probably damaging	Het
Akr1cl	A	T	1: 65,063,874 (GRCm39)	L105H	probably damaging	Het
Ano1	A	G	7: 144,207,993 (GRCm39)	F256S	probably damaging	Het
Arfip2	C	T	7: 105,287,150 (GRCm39)	R138H	probably damaging	Het
Cers6	T	A	2: 68,692,128 (GRCm39)	M50K	probably benign	Het
Dnah1	G	A	14: 31,037,079 (GRCm39)	Q256*	probably null	Het
Dync1h1	G	A	12: 110,585,644 (GRCm39)	E852K	possibly damaging	Het
Fars2	C	T	13: 36,721,384 (GRCm39)	Q443*	probably null	Het
Glb1l3	T	C	9: 26,770,748 (GRCm39)	N106S	probably damaging	Het
Haus7	T	C	X: 72,496,670 (GRCm39)		probably null	Het
Hectd1	C	T	12: 51,847,671 (GRCm39)		probably benign	Het
Hyal5	G	T	6: 24,877,881 (GRCm39)	G326C	probably damaging	Het
Ibtk	A	T	9: 85,603,189 (GRCm39)	D605E	probably benign	Het
Kif26b	T	C	1: 178,649,125 (GRCm39)	L415P	probably benign	Het
Lrrc37a	C	T	11: 103,388,499 (GRCm39)	E2309K	unknown	Het
Muc5b	A	G	7: 141,395,117 (GRCm39)	D41G	unknown	Het
Ncoa6	T	C	2: 155,249,207 (GRCm39)	T1366A	probably damaging	Het
Nmd3	C	T	3: 69,637,762 (GRCm39)		probably null	Het
Or6c206	T	C	10: 129,097,196 (GRCm39)	V122A	probably benign	Het
Pla2g4a	T	C	1: 149,727,118 (GRCm39)	N546S	probably damaging	Het
Prkcz	T	C	4: 155,371,247 (GRCm39)	T139A	possibly damaging	Het
Rarb	T	C	14: 16,434,168 (GRCm38)	K337E	probably damaging	Het
Rps6ka4	C	T	19: 6,809,615 (GRCm39)		probably benign	Het
Scamp2	A	G	9: 57,485,023 (GRCm39)		probably null	Het
Scn3a	T	A	2: 65,327,860 (GRCm39)	M877L	probably benign	Het
Sh3pxd2b	T	C	11: 32,361,448 (GRCm39)		probably benign	Het
Slc22a29	C	T	19: 8,140,012 (GRCm39)		probably null	Het
Slc34a1	T	C	13: 24,005,094 (GRCm39)		probably null	Het
Srbd1	A	T	17: 86,428,087 (GRCm39)	I382N	possibly damaging	Het
Tm7sf2	T	C	19: 6,112,958 (GRCm39)	I387M	probably benign	Het
Wfs1	C	A	5: 37,125,731 (GRCm39)	E311*	probably null	Het
Zc3h13	G	A	14: 75,531,381 (GRCm39)	R93H	probably damaging	Het

Other mutations in Mxra7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02017:Mxra7	APN	11	116,702,747 (GRCm39)	critical splice donor site	probably null
R0519:Mxra7	UTSW	11	116,701,612 (GRCm39)	critical splice donor site	probably null
R1115:Mxra7	UTSW	11	116,701,696 (GRCm39)	splice site	probably benign
R1741:Mxra7	UTSW	11	116,707,070 (GRCm39)	critical splice acceptor site	probably null
R4690:Mxra7	UTSW	11	116,707,078 (GRCm39)	splice site	probably null
R8313:Mxra7	UTSW	11	116,695,376 (GRCm39)	missense	probably damaging	1.00
Z1088:Mxra7	UTSW	11	116,695,432 (GRCm39)	missense	probably benign	0.29

Posted On

2016-08-02