Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03325:Gm5800'

416603

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm5800

Ensembl Gene

ENSMUSG00000068506

Gene Name

predicted gene 5800

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.083) question?

Stock #

IGL03325

Quality Score

Status

Chromosome

Chromosomal Location

51949101-51954589 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 51951983 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Cysteine at position 93 (Y93C)

Ref Sequence

ENSEMBL: ENSMUSP00000093605 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000095916]

AlphaFold

Q497L3

Predicted Effect

probably benign
Transcript: ENSMUST00000095916
AA Change: Y93C

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000093605
Gene: ENSMUSG00000068506
AA Change: Y93C

Domain	Start	End	E-Value	Type
Pfam:Takusan	10	90	4.7e-28	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca8b	G	A	11: 109,844,422 (GRCm39)	R870C	possibly damaging	Het
Abcf2	A	T	5: 24,779,210 (GRCm39)	L113I	probably damaging	Het
Abi1	C	T	2: 22,861,240 (GRCm39)	R106Q	probably damaging	Het
Arhgef28	A	G	13: 98,036,324 (GRCm39)	V1645A	probably benign	Het
Ccdc198	A	T	14: 49,481,277 (GRCm39)		probably benign	Het
Ceacam1	G	A	7: 25,175,912 (GRCm39)	A94V	possibly damaging	Het
Fat2	G	A	11: 55,173,168 (GRCm39)	T2515I	probably damaging	Het
Gnl1	A	G	17: 36,299,548 (GRCm39)	D573G	probably damaging	Het
Gosr1	A	G	11: 76,645,229 (GRCm39)	M105T	probably benign	Het
Gramd1c	A	T	16: 43,825,868 (GRCm39)	Y303N	probably benign	Het
Heatr9	A	G	11: 83,404,085 (GRCm39)		probably null	Het
Iigp1c	T	A	18: 60,378,883 (GRCm39)	Y139*	probably null	Het
Itih2	T	C	2: 10,111,546 (GRCm39)	D464G	probably damaging	Het
Jcad	T	C	18: 4,673,902 (GRCm39)	Y555H	probably benign	Het
Krtap19-3	A	T	16: 88,674,609 (GRCm39)	*88R	probably null	Het
Mrps11	T	C	7: 78,440,453 (GRCm39)	F114S	probably damaging	Het
Nat8	A	T	6: 85,807,875 (GRCm39)	V86E	possibly damaging	Het
Nek5	T	C	8: 22,569,158 (GRCm39)	T555A	probably benign	Het
Or6c3	A	T	10: 129,309,474 (GRCm39)	K304N	probably benign	Het
Pprc1	C	T	19: 46,049,948 (GRCm39)	T10I	possibly damaging	Het
Prss16	A	G	13: 22,187,417 (GRCm39)	V409A	possibly damaging	Het
Sema3d	T	A	5: 12,513,189 (GRCm39)	L53Q	probably damaging	Het
Sfmbt2	T	C	2: 10,582,628 (GRCm39)	Y696H	probably damaging	Het
Sh2d3c	C	T	2: 32,615,270 (GRCm39)	A120V	probably benign	Het
Smn1	A	G	13: 100,264,365 (GRCm39)	Y32C	probably damaging	Het
Sun2	C	T	15: 79,622,849 (GRCm39)	R110Q	probably benign	Het
Tcp11l2	T	G	10: 84,440,764 (GRCm39)	D323E	possibly damaging	Het
Tex55	A	T	16: 38,648,355 (GRCm39)	S251R	probably damaging	Het
Tnni3k	A	T	3: 154,667,451 (GRCm39)	S296R	probably damaging	Het
Uck1	G	A	2: 32,148,334 (GRCm39)	R161C	probably benign	Het
Unc79	T	A	12: 103,135,869 (GRCm39)	S2435T	probably damaging	Het
Vmn2r114	C	A	17: 23,510,652 (GRCm39)	K609N	probably damaging	Het

Other mutations in Gm5800

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00958:Gm5800	APN	14	51,951,269 (GRCm39)	missense	possibly damaging	0.96
R0037:Gm5800	UTSW	14	51,953,605 (GRCm39)	splice site	probably benign
R0597:Gm5800	UTSW	14	51,953,461 (GRCm39)	missense	probably benign
R1577:Gm5800	UTSW	14	51,952,016 (GRCm39)	missense	probably benign	0.05
R1834:Gm5800	UTSW	14	51,953,549 (GRCm39)	missense	possibly damaging	0.85
R1934:Gm5800	UTSW	14	51,949,396 (GRCm39)	missense	possibly damaging	0.96
R2169:Gm5800	UTSW	14	51,951,135 (GRCm39)	missense	possibly damaging	0.53
R2180:Gm5800	UTSW	14	51,953,451 (GRCm39)	nonsense	probably null
R4861:Gm5800	UTSW	14	51,953,504 (GRCm39)	missense	probably damaging	0.98
R4861:Gm5800	UTSW	14	51,953,504 (GRCm39)	missense	probably damaging	0.98
R5267:Gm5800	UTSW	14	51,951,294 (GRCm39)	splice site	probably null
R6545:Gm5800	UTSW	14	51,949,419 (GRCm39)	missense	possibly damaging	0.73
R6634:Gm5800	UTSW	14	51,953,595 (GRCm39)	missense	possibly damaging	0.73
R6925:Gm5800	UTSW	14	51,951,157 (GRCm39)	missense	possibly damaging	0.76
R7632:Gm5800	UTSW	14	51,953,905 (GRCm39)	splice site	probably null
R9067:Gm5800	UTSW	14	51,951,995 (GRCm39)	missense	possibly damaging	0.92

Posted On

2016-08-02