Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03327:Gm17079'

416672

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm17079

Ensembl Gene

ENSMUSG00000090740

Gene Name

predicted gene 17079

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL03327

Quality Score

Status

Chromosome

Chromosomal Location

51928476-51932925 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 51930420 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 142 (T142A)

Ref Sequence

ENSEMBL: ENSMUSP00000125788 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000167231]

AlphaFold

F7D8Y4

Predicted Effect

possibly damaging
Transcript: ENSMUST00000167231
AA Change: T142A

PolyPhen 2 Score 0.651 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000125788
Gene: ENSMUSG00000090740
AA Change: T142A

Domain	Start	End	E-Value	Type
Pfam:Takusan	57	135	1.3e-24	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adcy8	T	C	15: 64,792,116 (GRCm39)	Y280C	probably damaging	Het
Anapc1	T	C	2: 128,465,854 (GRCm39)	T1647A	probably benign	Het
Ano3	T	C	2: 110,527,523 (GRCm39)	I562V	possibly damaging	Het
Ash1l	C	T	3: 88,930,390 (GRCm39)	P1956S	probably benign	Het
Ccdc9b	T	C	2: 118,592,151 (GRCm39)	N79S	probably damaging	Het
Cd160	C	T	3: 96,712,849 (GRCm39)		probably null	Het
Chd3	G	T	11: 69,241,012 (GRCm39)	A1527E	probably damaging	Het
Clcn1	C	T	6: 42,288,153 (GRCm39)	T797I	probably benign	Het
Cntnap3	G	A	13: 65,035,582 (GRCm39)	Q44*	probably null	Het
Cntnap4	A	G	8: 113,500,208 (GRCm39)	D500G	probably benign	Het
Col6a6	T	C	9: 105,644,433 (GRCm39)	D1285G	possibly damaging	Het
Cr2	A	T	1: 194,852,067 (GRCm39)	V94E	probably damaging	Het
Dcaf1	T	C	9: 106,735,823 (GRCm39)	S924P	possibly damaging	Het
Eif5b	T	C	1: 38,080,772 (GRCm39)		probably benign	Het
Fat1	A	C	8: 45,403,505 (GRCm39)	K85N	probably damaging	Het
Fnip2	T	C	3: 79,425,388 (GRCm39)	E69G	probably damaging	Het
Fzr1	T	C	10: 81,205,018 (GRCm39)	T300A	probably benign	Het
Galc	A	G	12: 98,173,735 (GRCm39)		probably benign	Het
Hibch	G	A	1: 52,959,539 (GRCm39)		probably benign	Het
Hmmr	A	G	11: 40,606,242 (GRCm39)	C243R	probably damaging	Het
Il25	T	C	14: 55,172,817 (GRCm39)		probably benign	Het
Kif5b	G	A	18: 6,222,767 (GRCm39)	R355W	probably damaging	Het
Kifc3	C	T	8: 95,835,060 (GRCm39)	D242N	probably damaging	Het
Lig1	T	G	7: 13,037,781 (GRCm39)	I677S	probably damaging	Het
Lrig1	G	T	6: 94,583,104 (GRCm39)	A1004E	probably benign	Het
Nras	A	G	3: 102,966,340 (GRCm39)	T35A	probably damaging	Het
Nt5c1b	C	T	12: 10,424,861 (GRCm39)	Q136*	probably null	Het
Or4f54	A	T	2: 111,122,807 (GRCm39)	N65Y	probably damaging	Het
Or6c217	T	G	10: 129,738,451 (GRCm39)	I43L	possibly damaging	Het
Or8k1	C	T	2: 86,047,618 (GRCm39)	W145*	probably null	Het
Plcb3	A	G	19: 6,932,420 (GRCm39)	F1080L	probably benign	Het
Plpp2	T	C	10: 79,366,818 (GRCm39)		probably null	Het
Ptpre	G	A	7: 135,274,551 (GRCm39)		probably null	Het
Scn3a	G	A	2: 65,367,016 (GRCm39)	A2V	probably damaging	Het
Sh3bp4	C	A	1: 89,071,885 (GRCm39)	Y244*	probably null	Het
Trip11	A	T	12: 101,849,677 (GRCm39)	N1462K	possibly damaging	Het
Ttc21b	T	C	2: 66,068,192 (GRCm39)	D278G	possibly damaging	Het
Virma	A	G	4: 11,518,984 (GRCm39)	T694A	probably benign	Het
Wdr35	T	C	12: 9,028,694 (GRCm39)		probably benign	Het
Xdh	T	C	17: 74,223,787 (GRCm39)	E535G	probably benign	Het

Other mutations in Gm17079

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02368:Gm17079	APN	14	51,930,524 (GRCm39)	missense	possibly damaging	0.95
IGL03039:Gm17079	APN	14	51,930,518 (GRCm39)	missense	probably damaging	1.00
IGL03346:Gm17079	APN	14	51,930,420 (GRCm39)	missense	possibly damaging	0.65
R1487:Gm17079	UTSW	14	51,930,542 (GRCm39)	splice site	probably null
R6612:Gm17079	UTSW	14	51,931,833 (GRCm39)	missense	possibly damaging	0.85
R6612:Gm17079	UTSW	14	51,931,832 (GRCm39)	missense	probably damaging	1.00
R7028:Gm17079	UTSW	14	51,930,494 (GRCm39)	missense
R8080:Gm17079	UTSW	14	51,930,480 (GRCm39)	missense
R8288:Gm17079	UTSW	14	51,931,815 (GRCm39)	missense
R8690:Gm17079	UTSW	14	51,932,787 (GRCm39)	missense

Posted On

2016-08-02