Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03333:Zfp784'

416934

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp784

Ensembl Gene

ENSMUSG00000043290

Gene Name

zinc finger protein 784

Synonyms

C730049F21Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.231) question?

Stock #

IGL03333

Quality Score

Status

Chromosome

Chromosomal Location

5037445-5041445 bp(-) (GRCm39)

Type of Mutation

intron

DNA Base Change (assembly)

C to T at 5039351 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000146978 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000062428] [ENSMUST00000076251] [ENSMUST00000076791] [ENSMUST00000085427] [ENSMUST00000207050] [ENSMUST00000208728]

AlphaFold

Q8BI69

Predicted Effect

unknown
Transcript: ENSMUST00000062428
AA Change: C69Y

SMART Domains

Protein: ENSMUSP00000051979
Gene: ENSMUSG00000043290
AA Change: C69Y

Domain	Start	End	E-Value	Type
low complexity region	8	24	N/A	INTRINSIC
ZnF_C2H2	64	86	1.02e1	SMART
ZnF_C2H2	100	122	9.96e-1	SMART
ZnF_C2H2	128	150	6.67e-2	SMART
low complexity region	180	192	N/A	INTRINSIC
ZnF_C2H2	195	217	4.11e-2	SMART
ZnF_C2H2	223	245	7.26e-3	SMART
ZnF_C2H2	251	273	3.21e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000076251

SMART Domains

Protein: ENSMUSP00000075601
Gene: ENSMUSG00000074405

Domain	Start	End	E-Value	Type
low complexity region	6	20	N/A	INTRINSIC
low complexity region	62	82	N/A	INTRINSIC
low complexity region	120	141	N/A	INTRINSIC
low complexity region	171	193	N/A	INTRINSIC
ZnF_C2H2	220	242	1.28e-3	SMART
ZnF_C2H2	248	270	5.5e-3	SMART
low complexity region	274	286	N/A	INTRINSIC
low complexity region	294	324	N/A	INTRINSIC
ZnF_C2H2	350	372	8.81e-2	SMART
ZnF_C2H2	378	400	6.08e-5	SMART
ZnF_C2H2	407	429	1.79e-2	SMART
ZnF_C2H2	439	461	1.92e-2	SMART
low complexity region	478	495	N/A	INTRINSIC
low complexity region	502	516	N/A	INTRINSIC
low complexity region	523	542	N/A	INTRINSIC
ZnF_C2H2	546	568	4.47e-3	SMART
ZnF_C2H2	574	596	5.42e-2	SMART
ZnF_C2H2	602	624	1.72e-4	SMART
low complexity region	628	660	N/A	INTRINSIC
ZnF_C2H2	664	686	5.34e-1	SMART
ZnF_C2H2	692	714	2.82e0	SMART
low complexity region	725	745	N/A	INTRINSIC
low complexity region	750	770	N/A	INTRINSIC
low complexity region	772	788	N/A	INTRINSIC
ZnF_C2H2	791	813	1.64e-1	SMART
ZnF_C2H2	819	841	9.3e-1	SMART
ZnF_C2H2	847	869	2.95e-3	SMART
ZnF_C2H2	875	897	3.83e-2	SMART
ZnF_C2H2	903	925	2.05e-2	SMART
ZnF_C2H2	931	953	1.18e-2	SMART
ZnF_C2H2	959	981	1.36e-2	SMART
ZnF_C2H2	988	1010	5.06e-2	SMART
ZnF_C2H2	1016	1038	4.72e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000076791

Predicted Effect

probably benign
Transcript: ENSMUST00000085427

SMART Domains

Protein: ENSMUSP00000082550
Gene: ENSMUSG00000074405

Domain	Start	End	E-Value	Type
low complexity region	6	20	N/A	INTRINSIC
low complexity region	62	82	N/A	INTRINSIC
low complexity region	120	141	N/A	INTRINSIC
low complexity region	171	193	N/A	INTRINSIC
ZnF_C2H2	220	242	1.28e-3	SMART
ZnF_C2H2	248	270	5.5e-3	SMART
low complexity region	274	286	N/A	INTRINSIC
low complexity region	294	324	N/A	INTRINSIC
ZnF_C2H2	350	372	8.81e-2	SMART
ZnF_C2H2	378	400	6.08e-5	SMART
ZnF_C2H2	407	429	1.79e-2	SMART
ZnF_C2H2	439	461	1.92e-2	SMART
low complexity region	478	495	N/A	INTRINSIC
low complexity region	502	516	N/A	INTRINSIC
low complexity region	523	542	N/A	INTRINSIC
ZnF_C2H2	546	568	4.47e-3	SMART
ZnF_C2H2	574	596	5.42e-2	SMART
ZnF_C2H2	602	624	1.72e-4	SMART
low complexity region	628	660	N/A	INTRINSIC
ZnF_C2H2	664	686	5.34e-1	SMART
ZnF_C2H2	692	714	2.82e0	SMART
low complexity region	725	745	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000207050

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000207193

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000207362

Predicted Effect

probably benign
Transcript: ENSMUST00000208728

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Arhgap39	T	C	15: 76,610,932 (GRCm39)	M893V	probably benign	Het
Ccdc185	C	A	1: 182,576,398 (GRCm39)	G97V	probably damaging	Het
Cep170	T	C	1: 176,597,092 (GRCm39)	T422A	possibly damaging	Het
Ckap2l	A	C	2: 129,138,228 (GRCm39)		probably null	Het
Cpa3	A	G	3: 20,269,992 (GRCm39)	Y411H	possibly damaging	Het
Dnah2	C	A	11: 69,385,949 (GRCm39)	R1011L	probably damaging	Het
Efnb2	T	A	8: 8,689,275 (GRCm39)	K30*	probably null	Het
Ep400	C	T	5: 110,851,432 (GRCm39)	R1350H	unknown	Het
Epha6	T	C	16: 59,503,051 (GRCm39)	D952G	probably damaging	Het
Exoc7	C	A	11: 116,191,987 (GRCm39)	V195L	probably benign	Het
Fbxw8	T	C	5: 118,233,660 (GRCm39)	M324V	possibly damaging	Het
Fchsd2	T	C	7: 100,847,703 (GRCm39)	S198P	probably damaging	Het
Gcdh	T	C	8: 85,617,700 (GRCm39)	T202A	probably benign	Het
Gm6619	G	A	6: 131,467,471 (GRCm39)		probably benign	Het
Itpr1	A	T	6: 108,357,871 (GRCm39)		probably benign	Het
Kif2c	A	C	4: 117,037,833 (GRCm39)	V31G	possibly damaging	Het
Kpna7	T	C	5: 144,942,765 (GRCm39)	I74V	possibly damaging	Het
Lvrn	G	A	18: 46,997,731 (GRCm39)		probably benign	Het
Man2b2	T	A	5: 36,973,483 (GRCm39)	I499F	probably damaging	Het
Mmd2	G	T	5: 142,553,693 (GRCm39)		probably benign	Het
Or11h7	C	T	14: 50,890,855 (GRCm39)	Q54*	probably null	Het
Or2r11	T	C	6: 42,437,773 (GRCm39)	Y60C	probably damaging	Het
Or6b1	T	A	6: 42,815,637 (GRCm39)	I274N	possibly damaging	Het
Or8g2b	T	A	9: 39,751,308 (GRCm39)	Y193N	probably damaging	Het
Parp14	A	G	16: 35,661,800 (GRCm39)	S1412P	probably benign	Het
Prr30	A	T	14: 101,435,827 (GRCm39)	V245E	possibly damaging	Het
Ros1	T	A	10: 52,031,267 (GRCm39)	D458V	probably damaging	Het
Sec22c	A	G	9: 121,517,284 (GRCm39)	L138P	probably damaging	Het
Sema6d	C	A	2: 124,506,290 (GRCm39)	H699Q	possibly damaging	Het
Spata17	A	T	1: 186,872,667 (GRCm39)	M1K	probably null	Het
Tpr	T	A	1: 150,302,718 (GRCm39)	D1331E	probably benign	Het
Ttc4	A	G	4: 106,533,828 (GRCm39)	Y120H	probably benign	Het
Tubgcp4	A	G	2: 121,026,654 (GRCm39)		probably null	Het
Usp19	T	A	9: 108,371,348 (GRCm39)	M285K	probably benign	Het
Vmn1r222	A	T	13: 23,417,177 (GRCm39)	F12Y	probably benign	Het
Vmn2r72	T	C	7: 85,400,075 (GRCm39)	K325E	probably benign	Het
Vps33b	T	C	7: 79,923,973 (GRCm39)		probably benign	Het

Other mutations in Zfp784

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01516:Zfp784	APN	7	5,039,036 (GRCm39)	intron	probably benign
IGL02239:Zfp784	APN	7	5,038,670 (GRCm39)	intron	probably benign
R1464:Zfp784	UTSW	7	5,038,800 (GRCm39)	missense	possibly damaging	0.71
R1464:Zfp784	UTSW	7	5,038,800 (GRCm39)	missense	possibly damaging	0.71
R1515:Zfp784	UTSW	7	5,039,039 (GRCm39)	intron	probably benign
R1604:Zfp784	UTSW	7	5,039,453 (GRCm39)	intron	probably benign
R1606:Zfp784	UTSW	7	5,038,774 (GRCm39)	missense	possibly damaging	0.85
R1723:Zfp784	UTSW	7	5,038,782 (GRCm39)	missense	possibly damaging	0.71
R2428:Zfp784	UTSW	7	5,041,357 (GRCm39)	intron	probably benign
R2680:Zfp784	UTSW	7	5,039,116 (GRCm39)	missense	possibly damaging	0.86
R8083:Zfp784	UTSW	7	5,038,905 (GRCm39)	missense	possibly damaging	0.53
R8143:Zfp784	UTSW	7	5,038,910 (GRCm39)	missense	possibly damaging	0.93
R9382:Zfp784	UTSW	7	5,041,338 (GRCm39)	missense	unknown

Posted On

2016-08-02