Incidental Mutation 'IGL03101:Clec12b'
ID418747
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Clec12b
Ensembl Gene ENSMUSG00000030158
Gene NameC-type lectin domain family 12, member B
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.052) question?
Stock #IGL03101
Quality Score
Status
Chromosome6
Chromosomal Location129375515-129385874 bp(-) (GRCm38)
Type of Mutationsplice site (6 bp from exon)
DNA Base Change (assembly) A to G at 129379517 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000107713 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000032261] [ENSMUST00000112082]
Predicted Effect probably null
Transcript: ENSMUST00000032261
SMART Domains Protein: ENSMUSP00000032261
Gene: ENSMUSG00000030158

DomainStartEndE-ValueType
low complexity region 46 60 N/A INTRINSIC
CLECT 142 263 6.62e-25 SMART
Predicted Effect probably null
Transcript: ENSMUST00000112082
SMART Domains Protein: ENSMUSP00000107713
Gene: ENSMUSG00000030158

DomainStartEndE-ValueType
low complexity region 46 60 N/A INTRINSIC
CLECT 142 263 6.62e-25 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
AA474408 A T 7: 110,060,970 probably benign Het
Abcc1 T A 16: 14,389,868 V23D probably damaging Het
Adam8 G T 7: 139,988,543 N260K possibly damaging Het
Ap3b1 A T 13: 94,455,398 I457L probably benign Het
Apaf1 T C 10: 91,031,559 N808S possibly damaging Het
Arhgef26 A G 3: 62,419,661 T532A possibly damaging Het
Cfap65 G T 1: 74,928,433 T162N possibly damaging Het
Creb3 T C 4: 43,563,081 V60A probably benign Het
Cyp11b1 A G 15: 74,835,854 F469L probably benign Het
Defb28 A T 2: 152,520,127 E69V possibly damaging Het
Etnppl T C 3: 130,622,318 L118S probably damaging Het
Fsip1 T C 2: 118,241,663 Y213C probably damaging Het
Glb1l2 A G 9: 26,765,125 W480R probably damaging Het
Gm12394 T C 4: 42,793,424 D236G possibly damaging Het
Herc1 A T 9: 66,487,997 M4205L probably benign Het
Kif5a A T 10: 127,235,609 probably benign Het
Lmbrd2 C T 15: 9,186,608 R557C probably damaging Het
Map4k3 A G 17: 80,655,855 probably null Het
Npc1 A G 18: 12,198,539 I858T probably benign Het
Olfr866 T C 9: 20,027,429 T170A probably benign Het
Pecam1 A G 11: 106,697,351 V92A probably damaging Het
Rbm43 A T 2: 51,926,745 I70N probably benign Het
Rps6kb1 T C 11: 86,502,882 Y474C probably benign Het
Slco2a1 G A 9: 103,077,006 G459R possibly damaging Het
Snca T A 6: 60,827,611 probably benign Het
Stap2 T A 17: 56,002,029 I113F probably damaging Het
Tas2r137 T C 6: 40,491,830 M198T probably benign Het
Trim9 T C 12: 70,346,654 E172G probably damaging Het
Ttll7 T C 3: 146,896,690 V81A possibly damaging Het
Vmn2r103 A G 17: 19,773,520 Y53C probably damaging Het
Vmn2r22 C A 6: 123,637,336 A432S probably benign Het
Zfp943 T C 17: 21,992,175 S81P probably damaging Het
Other mutations in Clec12b
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01014:Clec12b APN 6 129385430 missense probably damaging 0.98
IGL01328:Clec12b APN 6 129379554 missense probably damaging 1.00
IGL01985:Clec12b APN 6 129382371 splice site probably benign
R0662:Clec12b UTSW 6 129376237 missense probably damaging 1.00
R0786:Clec12b UTSW 6 129380688 missense probably benign 0.07
R1468:Clec12b UTSW 6 129380640 missense probably damaging 0.98
R1468:Clec12b UTSW 6 129380640 missense probably damaging 0.98
R1513:Clec12b UTSW 6 129376302 missense probably damaging 1.00
R4757:Clec12b UTSW 6 129380692 missense probably damaging 1.00
R5566:Clec12b UTSW 6 129385475 missense probably damaging 0.99
R5643:Clec12b UTSW 6 129379960 missense probably benign
R5644:Clec12b UTSW 6 129379960 missense probably benign
Posted On2016-08-02