Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03114:Muc5b'

419298

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Muc5b

Ensembl Gene

ENSMUSG00000066108

Gene Name

mucin 5, subtype B, tracheobronchial

Synonyms

MUC5, 2300002I04Rik, MUC9

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.159) question?

Stock #

IGL03114

Quality Score

Status

Chromosome

Chromosomal Location

141392807-141426821 bp(+) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to A at 141412556 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Stop codon at position 1834 (S1834*)

Ref Sequence

ENSEMBL: ENSMUSP00000128276 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000165147]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000165147
AA Change: S1834*

SMART Domains

Protein: ENSMUSP00000128276
Gene: ENSMUSG00000066108
AA Change: S1834*

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
VWD	73	228	1.12e-25	SMART
C8	267	330	7.26e-8	SMART
Pfam:TIL	333	389	1.1e-13	PFAM
VWC	391	459	1.35e-1	SMART
VWD	418	582	2.87e-37	SMART
C8	619	693	2.53e-30	SMART
Pfam:TIL	699	756	2.6e-10	PFAM
VWC	758	823	1.26e0	SMART
VWC	861	930	1.58e-7	SMART
VWD	888	1048	3e-40	SMART
C8	1084	1158	3.75e-33	SMART
low complexity region	1314	1328	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1345	1432	6.7e-27	PFAM
low complexity region	1447	1468	N/A	INTRINSIC
low complexity region	1498	1517	N/A	INTRINSIC
low complexity region	1543	1558	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1574	1663	2.1e-26	PFAM
low complexity region	1678	1693	N/A	INTRINSIC
low complexity region	1728	1745	N/A	INTRINSIC
low complexity region	1778	1831	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1870	1959	2.7e-26	PFAM
low complexity region	1967	1990	N/A	INTRINSIC
low complexity region	2024	2041	N/A	INTRINSIC
low complexity region	2074	2127	N/A	INTRINSIC
Pfam:Mucin2_WxxW	2184	2273	2.1e-26	PFAM
low complexity region	2281	2304	N/A	INTRINSIC
low complexity region	2338	2355	N/A	INTRINSIC
low complexity region	2388	2441	N/A	INTRINSIC
Pfam:Mucin2_WxxW	2498	2587	2.1e-26	PFAM
low complexity region	2596	2618	N/A	INTRINSIC
low complexity region	2623	2654	N/A	INTRINSIC
low complexity region	2660	2681	N/A	INTRINSIC
Pfam:Mucin2_WxxW	2687	2776	3.8e-25	PFAM
low complexity region	2781	2796	N/A	INTRINSIC
low complexity region	2958	3009	N/A	INTRINSIC
Pfam:Mucin2_WxxW	3066	3155	2.6e-26	PFAM
low complexity region	3220	3237	N/A	INTRINSIC
low complexity region	3270	3317	N/A	INTRINSIC
Pfam:Mucin2_WxxW	3380	3469	3.4e-26	PFAM
low complexity region	3509	3529	N/A	INTRINSIC
low complexity region	3546	3562	N/A	INTRINSIC
low complexity region	3568	3591	N/A	INTRINSIC
Pfam:Mucin2_WxxW	3624	3713	2.6e-27	PFAM
Pfam:Mucin2_WxxW	3778	3867	3.2e-24	PFAM
low complexity region	3883	3900	N/A	INTRINSIC
low complexity region	3910	3934	N/A	INTRINSIC
low complexity region	3959	3976	N/A	INTRINSIC
low complexity region	4033	4053	N/A	INTRINSIC
VWD	4111	4283	6.75e-34	SMART
C8	4336	4403	4.26e-14	SMART
VWC	4461	4530	7.06e-5	SMART
VWC	4570	4631	6.53e-9	SMART
CT	4708	4790	2.93e-26	SMART

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]
PHENOTYPE: Mice homozygous for a knock-out allele accumulate materials in the upper and lower airways leading to chronic infection and inflammation that does not resolve and results in premature death. Macrophage function is impaired. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 56 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aadacl2fm2	A	T	3: 59,651,144 (GRCm39)	I89F	possibly damaging	Het
Abca13	T	A	11: 9,478,999 (GRCm39)	H4282Q	probably benign	Het
Acta2	A	G	19: 34,222,310 (GRCm39)		probably null	Het
Arl10	A	G	13: 54,723,579 (GRCm39)		probably benign	Het
Avpr1a	A	G	10: 122,285,623 (GRCm39)	Y305C	probably damaging	Het
Bmpr2	T	A	1: 59,906,603 (GRCm39)	N565K	probably damaging	Het
Boc	A	T	16: 44,307,115 (GRCm39)	S1035R	probably benign	Het
Brd10	A	T	19: 29,694,532 (GRCm39)	S1654T	probably benign	Het
Ccdc7a	T	C	8: 129,753,170 (GRCm39)	N187S	possibly damaging	Het
Cntn5	C	T	9: 9,748,457 (GRCm39)	E680K	probably damaging	Het
Copa	T	A	1: 171,946,835 (GRCm39)	Y1014*	probably null	Het
Csmd3	A	G	15: 47,683,847 (GRCm39)	S1662P	probably damaging	Het
Cyp2e1	T	C	7: 140,353,042 (GRCm39)	F360L	possibly damaging	Het
Efnb3	A	T	11: 69,447,628 (GRCm39)		probably benign	Het
Egf	A	T	3: 129,530,529 (GRCm39)	L211Q	probably damaging	Het
Eno1	G	A	4: 150,325,583 (GRCm39)	R56H	probably benign	Het
Fyb2	A	G	4: 104,852,975 (GRCm39)	T552A	probably damaging	Het
Git2	G	A	5: 114,871,918 (GRCm39)		probably benign	Het
Gtf2ird2	A	G	5: 134,245,752 (GRCm39)		probably null	Het
Hyal4	A	T	6: 24,755,964 (GRCm39)	I61L	probably benign	Het
Kat14	T	C	2: 144,217,885 (GRCm39)		probably null	Het
Kif13b	T	C	14: 65,025,897 (GRCm39)	V1418A	probably benign	Het
Lcn12	T	C	2: 25,383,274 (GRCm39)	K35E	probably benign	Het
Lyrm7	G	T	11: 54,741,198 (GRCm39)	N45K	possibly damaging	Het
Mical2	G	T	7: 111,996,764 (GRCm39)	G559V	probably damaging	Het
Mtrr	A	T	13: 68,712,441 (GRCm39)	C648*	probably null	Het
Mup16	G	A	4: 61,436,250 (GRCm39)	T101M	probably benign	Het
Myof	A	T	19: 37,892,309 (GRCm39)	L1148Q	probably damaging	Het
Nags	A	T	11: 102,039,814 (GRCm39)	I501F	probably damaging	Het
Nbeal1	A	T	1: 60,317,886 (GRCm39)	Y672F	probably damaging	Het
Ncapg2	A	G	12: 116,415,993 (GRCm39)		probably benign	Het
Obscn	A	G	11: 58,891,365 (GRCm39)	S7056P	unknown	Het
Or52s1	T	C	7: 102,861,928 (GRCm39)	I287T	probably damaging	Het
Pde2a	C	A	7: 101,157,890 (GRCm39)		probably benign	Het
Piezo2	T	C	18: 63,163,343 (GRCm39)		probably null	Het
Pkhd1	C	A	1: 20,268,395 (GRCm39)	D3328Y	probably damaging	Het
Plxdc2	T	C	2: 16,654,935 (GRCm39)	V178A	probably damaging	Het
Prdx3	T	C	19: 60,861,556 (GRCm39)		probably benign	Het
Prkce	T	A	17: 86,961,983 (GRCm39)	D694E	probably damaging	Het
Prss1l	T	A	6: 41,374,012 (GRCm39)	C205S	probably damaging	Het
Ptdss1	T	A	13: 67,142,058 (GRCm39)	Y405*	probably null	Het
Rad54l	A	T	4: 115,955,729 (GRCm39)	W608R	probably damaging	Het
Rassf6	G	T	5: 90,756,649 (GRCm39)		probably benign	Het
Sema5a	A	T	15: 32,673,573 (GRCm39)	I804F	probably damaging	Het
Slc15a2	A	T	16: 36,572,267 (GRCm39)	I668N	probably damaging	Het
Thsd7b	A	G	1: 130,116,288 (GRCm39)	E1347G	probably benign	Het
Tmco3	T	C	8: 13,348,205 (GRCm39)		probably benign	Het
Ttn	T	C	2: 76,551,996 (GRCm39)	M31214V	probably null	Het
Uck1	G	A	2: 32,148,334 (GRCm39)	R161C	probably benign	Het
Ugt2b5	T	C	5: 87,276,209 (GRCm39)	Y355C	probably damaging	Het
Usp48	C	A	4: 137,383,436 (GRCm39)	T1031K	probably damaging	Het
Vmn1r202	G	A	13: 22,685,640 (GRCm39)	T259I	probably benign	Het
Vmn1r202	T	A	13: 22,685,500 (GRCm39)		probably benign	Het
Vmn2r90	T	C	17: 17,953,771 (GRCm39)	I645T	probably damaging	Het
Vps18	T	C	2: 119,124,132 (GRCm39)	V353A	possibly damaging	Het
Vwf	C	T	6: 125,576,326 (GRCm39)	Q469*	probably null	Het

Other mutations in Muc5b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00586:Muc5b	APN	7	141,395,129 (GRCm39)	missense	unknown
IGL00677:Muc5b	APN	7	141,411,631 (GRCm39)	nonsense	probably null
IGL00740:Muc5b	APN	7	141,409,335 (GRCm39)	missense	unknown
IGL01084:Muc5b	APN	7	141,397,186 (GRCm39)	splice site	probably benign
IGL01384:Muc5b	APN	7	141,400,555 (GRCm39)	missense	unknown
IGL01447:Muc5b	APN	7	141,416,831 (GRCm39)	missense	probably benign	0.01
IGL01510:Muc5b	APN	7	141,412,798 (GRCm39)	missense	unknown
IGL01532:Muc5b	APN	7	141,423,743 (GRCm39)	missense	possibly damaging	0.96
IGL01556:Muc5b	APN	7	141,416,977 (GRCm39)	missense	probably benign	0.01
IGL01608:Muc5b	APN	7	141,400,174 (GRCm39)	missense	unknown
IGL01884:Muc5b	APN	7	141,421,820 (GRCm39)	splice site	probably benign
IGL01943:Muc5b	APN	7	141,415,234 (GRCm39)	missense	possibly damaging	0.71
IGL02039:Muc5b	APN	7	141,424,901 (GRCm39)	missense	possibly damaging	0.96
IGL02089:Muc5b	APN	7	141,416,987 (GRCm39)	missense	probably benign	0.04
IGL02110:Muc5b	APN	7	141,401,453 (GRCm39)	nonsense	probably null
IGL02123:Muc5b	APN	7	141,417,494 (GRCm39)	missense	possibly damaging	0.68
IGL02124:Muc5b	APN	7	141,409,369 (GRCm39)	missense	unknown
IGL02141:Muc5b	APN	7	141,407,104 (GRCm39)	missense	unknown
IGL02409:Muc5b	APN	7	141,415,075 (GRCm39)	missense	possibly damaging	0.53
IGL02448:Muc5b	APN	7	141,422,226 (GRCm39)	missense	possibly damaging	0.53
IGL02503:Muc5b	APN	7	141,421,404 (GRCm39)	missense	probably benign	0.33
IGL02504:Muc5b	APN	7	141,400,177 (GRCm39)	missense	unknown
IGL02528:Muc5b	APN	7	141,417,754 (GRCm39)	missense	probably benign	0.01
IGL02534:Muc5b	APN	7	141,398,456 (GRCm39)	missense	unknown
IGL02565:Muc5b	APN	7	141,411,604 (GRCm39)	missense	unknown
IGL02630:Muc5b	APN	7	141,416,968 (GRCm39)	missense	probably benign	0.03
IGL02881:Muc5b	APN	7	141,411,449 (GRCm39)	missense	unknown
IGL02963:Muc5b	APN	7	141,418,001 (GRCm39)	missense	probably damaging	1.00
IGL03003:Muc5b	APN	7	141,417,351 (GRCm39)	missense	probably benign	0.03
IGL03013:Muc5b	APN	7	141,417,665 (GRCm39)	missense	possibly damaging	0.68
IGL03102:Muc5b	APN	7	141,416,806 (GRCm39)	missense	probably benign	0.35
IGL03150:Muc5b	APN	7	141,419,246 (GRCm39)	missense	possibly damaging	0.53
IGL03185:Muc5b	APN	7	141,416,559 (GRCm39)	missense	possibly damaging	0.83
IGL03299:Muc5b	APN	7	141,395,117 (GRCm39)	missense	unknown
IGL03336:Muc5b	APN	7	141,418,100 (GRCm39)	missense	probably damaging	1.00
IGL03370:Muc5b	APN	7	141,418,514 (GRCm39)	missense	probably benign	0.34
IGL03375:Muc5b	APN	7	141,415,699 (GRCm39)	missense	possibly damaging	0.53
IGL03393:Muc5b	APN	7	141,417,875 (GRCm39)	missense	probably benign	0.21
profligate	UTSW	7	141,411,559 (GRCm39)	nonsense	probably null
wasteful	UTSW	7	141,411,898 (GRCm39)	missense	unknown
R0045:Muc5b	UTSW	7	141,410,555 (GRCm39)	missense	unknown
R0256:Muc5b	UTSW	7	141,396,995 (GRCm39)	missense	unknown
R0256:Muc5b	UTSW	7	141,395,132 (GRCm39)	missense	unknown
R0321:Muc5b	UTSW	7	141,415,972 (GRCm39)	missense	probably benign	0.19
R0391:Muc5b	UTSW	7	141,418,819 (GRCm39)	missense	possibly damaging	0.73
R0458:Muc5b	UTSW	7	141,418,709 (GRCm39)	missense	probably benign	0.20
R0491:Muc5b	UTSW	7	141,415,752 (GRCm39)	missense	probably benign	0.01
R0543:Muc5b	UTSW	7	141,405,522 (GRCm39)	missense	unknown
R0583:Muc5b	UTSW	7	141,410,435 (GRCm39)	nonsense	probably null
R0611:Muc5b	UTSW	7	141,416,173 (GRCm39)	missense	probably benign	0.18
R0625:Muc5b	UTSW	7	141,400,164 (GRCm39)	missense	unknown
R0655:Muc5b	UTSW	7	141,417,679 (GRCm39)	missense	probably benign	0.01
R0845:Muc5b	UTSW	7	141,404,183 (GRCm39)	splice site	probably null
R0863:Muc5b	UTSW	7	141,421,454 (GRCm39)	missense	probably benign	0.18
R0965:Muc5b	UTSW	7	141,417,539 (GRCm39)	missense	possibly damaging	0.92
R0988:Muc5b	UTSW	7	141,425,532 (GRCm39)	missense	probably benign	0.03
R1140:Muc5b	UTSW	7	141,412,733 (GRCm39)	missense	unknown
R1209:Muc5b	UTSW	7	141,411,647 (GRCm39)	missense	unknown
R1333:Muc5b	UTSW	7	141,422,144 (GRCm39)	missense	possibly damaging	0.53
R1337:Muc5b	UTSW	7	141,412,361 (GRCm39)	missense	unknown
R1385:Muc5b	UTSW	7	141,415,874 (GRCm39)	missense	probably benign	0.00
R1463:Muc5b	UTSW	7	141,412,817 (GRCm39)	missense	unknown
R1471:Muc5b	UTSW	7	141,396,971 (GRCm39)	missense	unknown
R1617:Muc5b	UTSW	7	141,417,261 (GRCm39)	nonsense	probably null
R1736:Muc5b	UTSW	7	141,412,844 (GRCm39)	missense	unknown
R1752:Muc5b	UTSW	7	141,421,488 (GRCm39)	missense	possibly damaging	0.96
R1804:Muc5b	UTSW	7	141,417,517 (GRCm39)	missense	possibly damaging	0.68
R1806:Muc5b	UTSW	7	141,419,230 (GRCm39)	missense	possibly damaging	0.68
R1895:Muc5b	UTSW	7	141,411,382 (GRCm39)	missense	unknown
R1902:Muc5b	UTSW	7	141,417,842 (GRCm39)	missense	possibly damaging	0.77
R1919:Muc5b	UTSW	7	141,399,768 (GRCm39)	missense	unknown
R1924:Muc5b	UTSW	7	141,421,960 (GRCm39)	missense	possibly damaging	0.53
R1942:Muc5b	UTSW	7	141,411,421 (GRCm39)	missense	unknown
R1959:Muc5b	UTSW	7	141,416,374 (GRCm39)	missense	possibly damaging	0.86
R1960:Muc5b	UTSW	7	141,416,374 (GRCm39)	missense	possibly damaging	0.86
R1976:Muc5b	UTSW	7	141,416,891 (GRCm39)	missense	probably benign	0.01
R2080:Muc5b	UTSW	7	141,423,491 (GRCm39)	missense	probably benign	0.33
R2178:Muc5b	UTSW	7	141,417,853 (GRCm39)	missense	possibly damaging	0.58
R2184:Muc5b	UTSW	7	141,412,601 (GRCm39)	nonsense	probably null
R2229:Muc5b	UTSW	7	141,415,381 (GRCm39)	missense	possibly damaging	0.71
R2237:Muc5b	UTSW	7	141,415,826 (GRCm39)	missense	probably benign	0.00
R2509:Muc5b	UTSW	7	141,412,798 (GRCm39)	missense	unknown
R2510:Muc5b	UTSW	7	141,412,798 (GRCm39)	missense	unknown
R2512:Muc5b	UTSW	7	141,412,813 (GRCm39)	missense	unknown
R2888:Muc5b	UTSW	7	141,415,291 (GRCm39)	missense	probably damaging	0.98
R3054:Muc5b	UTSW	7	141,417,778 (GRCm39)	missense	probably damaging	0.97
R3055:Muc5b	UTSW	7	141,417,778 (GRCm39)	missense	probably damaging	0.97
R3108:Muc5b	UTSW	7	141,412,496 (GRCm39)	missense	unknown
R3109:Muc5b	UTSW	7	141,412,496 (GRCm39)	missense	unknown
R3113:Muc5b	UTSW	7	141,399,871 (GRCm39)	missense	unknown
R3551:Muc5b	UTSW	7	141,415,072 (GRCm39)	missense	possibly damaging	0.53
R3552:Muc5b	UTSW	7	141,421,442 (GRCm39)	missense	probably benign	0.18
R3552:Muc5b	UTSW	7	141,415,072 (GRCm39)	missense	possibly damaging	0.53
R3622:Muc5b	UTSW	7	141,405,595 (GRCm39)	splice site	probably benign
R3700:Muc5b	UTSW	7	141,400,986 (GRCm39)	missense	unknown
R3734:Muc5b	UTSW	7	141,412,774 (GRCm39)	nonsense	probably null
R3785:Muc5b	UTSW	7	141,418,853 (GRCm39)	missense	possibly damaging	0.86
R3786:Muc5b	UTSW	7	141,418,853 (GRCm39)	missense	possibly damaging	0.86
R3788:Muc5b	UTSW	7	141,417,571 (GRCm39)	missense	possibly damaging	0.68
R3810:Muc5b	UTSW	7	141,417,863 (GRCm39)	missense	possibly damaging	0.58
R3834:Muc5b	UTSW	7	141,412,918 (GRCm39)	missense	unknown
R3835:Muc5b	UTSW	7	141,412,918 (GRCm39)	missense	unknown
R3850:Muc5b	UTSW	7	141,416,375 (GRCm39)	missense	possibly damaging	0.95
R3877:Muc5b	UTSW	7	141,411,289 (GRCm39)	missense	unknown
R3909:Muc5b	UTSW	7	141,403,235 (GRCm39)	missense	unknown
R3964:Muc5b	UTSW	7	141,420,705 (GRCm39)	missense	possibly damaging	0.73
R4014:Muc5b	UTSW	7	141,417,367 (GRCm39)	missense	probably benign	0.40
R4015:Muc5b	UTSW	7	141,417,367 (GRCm39)	missense	probably benign	0.40
R4017:Muc5b	UTSW	7	141,417,367 (GRCm39)	missense	probably benign	0.40
R4042:Muc5b	UTSW	7	141,418,624 (GRCm39)	missense	possibly damaging	0.92
R4200:Muc5b	UTSW	7	141,412,662 (GRCm39)	nonsense	probably null
R4230:Muc5b	UTSW	7	141,417,259 (GRCm39)	missense	probably benign	0.03
R4400:Muc5b	UTSW	7	141,415,124 (GRCm39)	missense	possibly damaging	0.92
R4455:Muc5b	UTSW	7	141,412,555 (GRCm39)	missense	unknown
R4484:Muc5b	UTSW	7	141,422,187 (GRCm39)	missense	possibly damaging	0.73
R4630:Muc5b	UTSW	7	141,411,721 (GRCm39)	missense	unknown
R4646:Muc5b	UTSW	7	141,416,377 (GRCm39)	missense	probably benign	0.34
R4658:Muc5b	UTSW	7	141,395,135 (GRCm39)	missense	unknown
R4667:Muc5b	UTSW	7	141,396,116 (GRCm39)	missense	unknown
R4690:Muc5b	UTSW	7	141,396,031 (GRCm39)	missense	unknown
R4697:Muc5b	UTSW	7	141,411,098 (GRCm39)	missense	unknown
R4711:Muc5b	UTSW	7	141,399,770 (GRCm39)	missense	unknown
R4713:Muc5b	UTSW	7	141,402,816 (GRCm39)	nonsense	probably null
R4749:Muc5b	UTSW	7	141,415,185 (GRCm39)	nonsense	probably null
R4753:Muc5b	UTSW	7	141,410,590 (GRCm39)	missense	unknown
R4782:Muc5b	UTSW	7	141,401,453 (GRCm39)	nonsense	probably null
R4795:Muc5b	UTSW	7	141,403,304 (GRCm39)	missense	unknown
R4796:Muc5b	UTSW	7	141,417,983 (GRCm39)	missense	possibly damaging	0.52
R4799:Muc5b	UTSW	7	141,401,453 (GRCm39)	nonsense	probably null
R4824:Muc5b	UTSW	7	141,417,922 (GRCm39)	missense	probably damaging	1.00
R4825:Muc5b	UTSW	7	141,422,202 (GRCm39)	missense	possibly damaging	0.96
R5068:Muc5b	UTSW	7	141,412,345 (GRCm39)	missense	unknown
R5073:Muc5b	UTSW	7	141,412,999 (GRCm39)	missense	unknown
R5074:Muc5b	UTSW	7	141,412,999 (GRCm39)	missense	unknown
R5107:Muc5b	UTSW	7	141,409,268 (GRCm39)	missense	unknown
R5152:Muc5b	UTSW	7	141,419,268 (GRCm39)	missense	possibly damaging	0.53
R5183:Muc5b	UTSW	7	141,404,547 (GRCm39)	missense	unknown
R5191:Muc5b	UTSW	7	141,412,276 (GRCm39)	missense	unknown
R5254:Muc5b	UTSW	7	141,418,277 (GRCm39)	missense	probably benign	0.09
R5320:Muc5b	UTSW	7	141,412,738 (GRCm39)	missense	unknown
R5352:Muc5b	UTSW	7	141,418,295 (GRCm39)	missense	possibly damaging	0.66
R5378:Muc5b	UTSW	7	141,415,940 (GRCm39)	missense	unknown
R5417:Muc5b	UTSW	7	141,411,781 (GRCm39)	missense	unknown
R5548:Muc5b	UTSW	7	141,417,679 (GRCm39)	missense	probably benign	0.01
R5551:Muc5b	UTSW	7	141,422,240 (GRCm39)	missense	possibly damaging	0.73
R5562:Muc5b	UTSW	7	141,400,975 (GRCm39)	missense	unknown
R5580:Muc5b	UTSW	7	141,415,084 (GRCm39)	missense	possibly damaging	0.53
R5629:Muc5b	UTSW	7	141,415,036 (GRCm39)	missense	possibly damaging	0.73
R5758:Muc5b	UTSW	7	141,412,720 (GRCm39)	missense	unknown
R5783:Muc5b	UTSW	7	141,412,165 (GRCm39)	nonsense	probably null
R5795:Muc5b	UTSW	7	141,425,478 (GRCm39)	missense	possibly damaging	0.96
R5796:Muc5b	UTSW	7	141,411,133 (GRCm39)	missense	unknown
R5797:Muc5b	UTSW	7	141,405,319 (GRCm39)	missense	unknown
R5806:Muc5b	UTSW	7	141,416,572 (GRCm39)	missense	possibly damaging	0.68
R5888:Muc5b	UTSW	7	141,412,158 (GRCm39)	missense	unknown
R5910:Muc5b	UTSW	7	141,415,048 (GRCm39)	missense	possibly damaging	0.53
R5956:Muc5b	UTSW	7	141,417,910 (GRCm39)	missense	probably damaging	0.99
R5970:Muc5b	UTSW	7	141,410,449 (GRCm39)	missense	unknown
R5990:Muc5b	UTSW	7	141,411,898 (GRCm39)	missense	unknown
R5999:Muc5b	UTSW	7	141,411,116 (GRCm39)	missense	unknown
R6001:Muc5b	UTSW	7	141,426,118 (GRCm39)	missense	possibly damaging	0.72
R6053:Muc5b	UTSW	7	141,418,445 (GRCm39)	missense	probably benign	0.07
R6073:Muc5b	UTSW	7	141,412,025 (GRCm39)	missense	unknown
R6073:Muc5b	UTSW	7	141,402,797 (GRCm39)	missense	unknown
R6112:Muc5b	UTSW	7	141,417,042 (GRCm39)	missense	probably benign	0.01
R6153:Muc5b	UTSW	7	141,415,181 (GRCm39)	missense	possibly damaging	0.71
R6164:Muc5b	UTSW	7	141,417,082 (GRCm39)	missense	possibly damaging	0.73
R6172:Muc5b	UTSW	7	141,412,513 (GRCm39)	missense	unknown
R6178:Muc5b	UTSW	7	141,410,079 (GRCm39)	missense	probably null
R6196:Muc5b	UTSW	7	141,405,333 (GRCm39)	missense	unknown
R6213:Muc5b	UTSW	7	141,421,356 (GRCm39)	missense	possibly damaging	0.92
R6213:Muc5b	UTSW	7	141,415,903 (GRCm39)	missense	probably benign	0.00
R6344:Muc5b	UTSW	7	141,416,708 (GRCm39)	missense	possibly damaging	0.62
R6400:Muc5b	UTSW	7	141,412,402 (GRCm39)	missense	unknown
R6414:Muc5b	UTSW	7	141,412,834 (GRCm39)	missense	unknown
R6521:Muc5b	UTSW	7	141,412,908 (GRCm39)	nonsense	probably null
R6658:Muc5b	UTSW	7	141,422,244 (GRCm39)	critical splice donor site	probably null
R6717:Muc5b	UTSW	7	141,411,559 (GRCm39)	nonsense	probably null
R6737:Muc5b	UTSW	7	141,411,236 (GRCm39)	missense	unknown
R6763:Muc5b	UTSW	7	141,416,021 (GRCm39)	missense	probably benign	0.01
R6817:Muc5b	UTSW	7	141,416,650 (GRCm39)	missense	probably benign	0.06
R6819:Muc5b	UTSW	7	141,412,600 (GRCm39)	missense	unknown
R6916:Muc5b	UTSW	7	141,418,454 (GRCm39)	missense	possibly damaging	0.71
R7030:Muc5b	UTSW	7	141,396,192 (GRCm39)	missense	unknown
R7116:Muc5b	UTSW	7	141,417,487 (GRCm39)	missense	probably benign	0.10
R7134:Muc5b	UTSW	7	141,411,391 (GRCm39)	missense	unknown
R7146:Muc5b	UTSW	7	141,417,704 (GRCm39)	missense	possibly damaging	0.96
R7168:Muc5b	UTSW	7	141,417,754 (GRCm39)	missense	probably benign	0.01
R7182:Muc5b	UTSW	7	141,396,382 (GRCm39)	missense	unknown
R7189:Muc5b	UTSW	7	141,414,798 (GRCm39)	nonsense	probably null
R7207:Muc5b	UTSW	7	141,416,602 (GRCm39)	missense	probably benign	0.01
R7232:Muc5b	UTSW	7	141,419,866 (GRCm39)	missense	possibly damaging	0.53
R7260:Muc5b	UTSW	7	141,396,385 (GRCm39)	missense	unknown
R7269:Muc5b	UTSW	7	141,411,272 (GRCm39)	missense	unknown
R7273:Muc5b	UTSW	7	141,405,307 (GRCm39)	missense	unknown
R7278:Muc5b	UTSW	7	141,411,239 (GRCm39)	missense	unknown
R7307:Muc5b	UTSW	7	141,396,031 (GRCm39)	missense	unknown
R7323:Muc5b	UTSW	7	141,412,444 (GRCm39)	missense	unknown
R7374:Muc5b	UTSW	7	141,416,863 (GRCm39)	missense	probably benign	0.10
R7376:Muc5b	UTSW	7	141,426,287 (GRCm39)	missense	possibly damaging	0.53
R7382:Muc5b	UTSW	7	141,412,685 (GRCm39)	missense	unknown
R7481:Muc5b	UTSW	7	141,414,908 (GRCm39)	missense	unknown
R7497:Muc5b	UTSW	7	141,415,250 (GRCm39)	missense	possibly damaging	0.92
R7554:Muc5b	UTSW	7	141,412,513 (GRCm39)	missense	unknown
R7571:Muc5b	UTSW	7	141,400,986 (GRCm39)	missense	unknown
R7598:Muc5b	UTSW	7	141,412,999 (GRCm39)	missense	unknown
R7609:Muc5b	UTSW	7	141,415,466 (GRCm39)	missense	possibly damaging	0.86
R7615:Muc5b	UTSW	7	141,418,629 (GRCm39)	nonsense	probably null
R7618:Muc5b	UTSW	7	141,421,334 (GRCm39)	missense	probably benign	0.01
R7651:Muc5b	UTSW	7	141,417,760 (GRCm39)	missense	possibly damaging	0.75
R7692:Muc5b	UTSW	7	141,406,966 (GRCm39)	missense	unknown
R7731:Muc5b	UTSW	7	141,411,042 (GRCm39)	critical splice acceptor site	probably null
R7746:Muc5b	UTSW	7	141,415,976 (GRCm39)	missense	probably benign	0.10
R7748:Muc5b	UTSW	7	141,401,542 (GRCm39)	missense	unknown
R7774:Muc5b	UTSW	7	141,396,116 (GRCm39)	missense	unknown
R7783:Muc5b	UTSW	7	141,411,078 (GRCm39)	missense	unknown
R7834:Muc5b	UTSW	7	141,412,807 (GRCm39)	missense	unknown
R7872:Muc5b	UTSW	7	141,399,850 (GRCm39)	missense	unknown
R7935:Muc5b	UTSW	7	141,400,569 (GRCm39)	missense	unknown
R8026:Muc5b	UTSW	7	141,417,373 (GRCm39)	missense	probably benign	0.03
R8036:Muc5b	UTSW	7	141,421,478 (GRCm39)	missense	possibly damaging	0.73
R8081:Muc5b	UTSW	7	141,417,743 (GRCm39)	missense	possibly damaging	0.88
R8096:Muc5b	UTSW	7	141,403,292 (GRCm39)	missense	unknown
R8101:Muc5b	UTSW	7	141,418,912 (GRCm39)	missense	possibly damaging	0.53
R8112:Muc5b	UTSW	7	141,415,765 (GRCm39)	missense	possibly damaging	0.53
R8131:Muc5b	UTSW	7	141,396,146 (GRCm39)	missense	unknown
R8170:Muc5b	UTSW	7	141,414,737 (GRCm39)	missense	unknown
R8171:Muc5b	UTSW	7	141,414,737 (GRCm39)	missense	unknown
R8191:Muc5b	UTSW	7	141,421,421 (GRCm39)	missense	probably benign	0.18
R8237:Muc5b	UTSW	7	141,411,697 (GRCm39)	missense	unknown
R8342:Muc5b	UTSW	7	141,414,602 (GRCm39)	missense	unknown
R8343:Muc5b	UTSW	7	141,417,898 (GRCm39)	missense	probably benign	0.28
R8389:Muc5b	UTSW	7	141,415,516 (GRCm39)	missense	possibly damaging	0.53
R8396:Muc5b	UTSW	7	141,405,552 (GRCm39)	missense	unknown
R8733:Muc5b	UTSW	7	141,417,532 (GRCm39)	missense	possibly damaging	0.68
R8774:Muc5b	UTSW	7	141,418,831 (GRCm39)	missense	probably benign	0.18
R8774-TAIL:Muc5b	UTSW	7	141,418,831 (GRCm39)	missense	probably benign	0.18
R8833:Muc5b	UTSW	7	141,412,105 (GRCm39)	missense	unknown
R8884:Muc5b	UTSW	7	141,403,156 (GRCm39)	missense	unknown
R8907:Muc5b	UTSW	7	141,417,875 (GRCm39)	missense	probably benign	0.21
R8944:Muc5b	UTSW	7	141,421,115 (GRCm39)	missense
R9025:Muc5b	UTSW	7	141,426,209 (GRCm39)	missense	probably damaging	0.98
R9044:Muc5b	UTSW	7	141,411,795 (GRCm39)	missense	unknown
R9117:Muc5b	UTSW	7	141,423,070 (GRCm39)	missense	possibly damaging	0.73
R9145:Muc5b	UTSW	7	141,411,350 (GRCm39)	missense	unknown
R9154:Muc5b	UTSW	7	141,417,974 (GRCm39)	missense	probably damaging	0.98
R9177:Muc5b	UTSW	7	141,399,075 (GRCm39)	missense	unknown
R9190:Muc5b	UTSW	7	141,411,939 (GRCm39)	missense	unknown
R9204:Muc5b	UTSW	7	141,410,129 (GRCm39)	missense	unknown
R9260:Muc5b	UTSW	7	141,405,255 (GRCm39)	missense	unknown
R9331:Muc5b	UTSW	7	141,411,475 (GRCm39)	missense	unknown
R9366:Muc5b	UTSW	7	141,417,041 (GRCm39)	missense	probably benign	0.01
R9402:Muc5b	UTSW	7	141,399,151 (GRCm39)	missense	unknown
R9462:Muc5b	UTSW	7	141,415,216 (GRCm39)	missense
R9463:Muc5b	UTSW	7	141,405,503 (GRCm39)	missense	unknown
R9490:Muc5b	UTSW	7	141,425,497 (GRCm39)	missense	probably benign	0.33
R9523:Muc5b	UTSW	7	141,396,116 (GRCm39)	missense	unknown
R9548:Muc5b	UTSW	7	141,421,648 (GRCm39)	missense	possibly damaging	0.52
R9591:Muc5b	UTSW	7	141,412,516 (GRCm39)	missense	unknown
R9602:Muc5b	UTSW	7	141,417,211 (GRCm39)	missense	probably benign	0.11
R9664:Muc5b	UTSW	7	141,409,279 (GRCm39)	missense	unknown
R9703:Muc5b	UTSW	7	141,425,535 (GRCm39)	missense	possibly damaging	0.53
R9713:Muc5b	UTSW	7	141,416,678 (GRCm39)	missense	probably benign	0.01
R9789:Muc5b	UTSW	7	141,415,330 (GRCm39)	missense	possibly damaging	0.95
R9800:Muc5b	UTSW	7	141,415,480 (GRCm39)	missense	possibly damaging	0.53
Z1088:Muc5b	UTSW	7	141,415,951 (GRCm39)	missense	probably benign	0.01
Z1176:Muc5b	UTSW	7	141,396,442 (GRCm39)	missense	unknown
Z1177:Muc5b	UTSW	7	141,416,910 (GRCm39)	missense	probably benign	0.04

Posted On

2016-08-02