Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03392:Commd7'

421120

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Commd7

Ensembl Gene

ENSMUSG00000056941

Gene Name

COMM domain containing 7

Synonyms

mU3, 2310010I22Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.221) question?

Stock #

IGL03392

Quality Score

Status

Chromosome

Chromosomal Location

153458853-153474701 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 153464684 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000105404 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000071852] [ENSMUST00000109782]

AlphaFold

Q8BG94

Predicted Effect

probably benign
Transcript: ENSMUST00000071852

SMART Domains

Protein: ENSMUSP00000071752
Gene: ENSMUSG00000056941

Domain	Start	End	E-Value	Type
Pfam:HCaRG	19	199	3.8e-44	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000109782

SMART Domains

Protein: ENSMUSP00000105404
Gene: ENSMUSG00000056941

Domain	Start	End	E-Value	Type
Pfam:HCaRG	1	127	4.4e-33	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000147822

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acss2	T	A	2: 155,403,931 (GRCm39)	D692E	probably damaging	Het
Adgrb3	T	A	1: 25,543,529 (GRCm39)	R366S	probably damaging	Het
Afg3l2	C	A	18: 67,547,139 (GRCm39)		probably benign	Het
Cd5	T	C	19: 10,703,653 (GRCm39)		probably benign	Het
Cnbd1	A	G	4: 18,862,111 (GRCm39)	S360P	probably damaging	Het
Col13a1	A	T	10: 61,721,490 (GRCm39)	L305I	possibly damaging	Het
Cpsf6	A	T	10: 117,203,884 (GRCm39)	Y23N	probably damaging	Het
Cry1	A	G	10: 84,992,993 (GRCm39)	V75A	possibly damaging	Het
Cyp2c39	A	G	19: 39,501,767 (GRCm39)	N107D	probably benign	Het
Dcaf11	T	A	14: 55,798,878 (GRCm39)	V45E	probably damaging	Het
Dnm2	A	G	9: 21,385,907 (GRCm39)	E310G	probably damaging	Het
Fat3	T	A	9: 15,915,158 (GRCm39)	I1597L	probably benign	Het
Fcamr	A	G	1: 130,728,685 (GRCm39)		probably benign	Het
Fer	A	G	17: 64,298,637 (GRCm39)	I529V	probably damaging	Het
Fhdc1	T	C	3: 84,351,826 (GRCm39)	K1133R	possibly damaging	Het
Foxd3	A	G	4: 99,545,432 (GRCm39)	K191E	probably damaging	Het
Fut2	C	T	7: 45,300,193 (GRCm39)	G193E	possibly damaging	Het
Gbp8	A	G	5: 105,164,410 (GRCm39)		probably null	Het
Glb1	T	G	9: 114,259,389 (GRCm39)	N106K	probably damaging	Het
Hpx	A	G	7: 105,241,609 (GRCm39)	I295T	probably damaging	Het
Ipo5	T	A	14: 121,180,099 (GRCm39)	D844E	probably damaging	Het
Krt17	T	C	11: 100,150,561 (GRCm39)	I159V	possibly damaging	Het
Lgi4	G	A	7: 30,762,605 (GRCm39)		probably null	Het
Lrrc49	T	C	9: 60,573,563 (GRCm39)		probably benign	Het
Ltn1	T	C	16: 87,222,499 (GRCm39)	K178R	probably damaging	Het
Myh8	T	A	11: 67,185,244 (GRCm39)	W832R	probably damaging	Het
Nbn	A	G	4: 15,962,362 (GRCm39)	N30S	probably damaging	Het
Or2j3	A	G	17: 38,615,786 (GRCm39)	S189P	probably benign	Het
Or4a72	A	T	2: 89,405,593 (GRCm39)	V159D	probably damaging	Het
Or4f59	T	A	2: 111,873,321 (GRCm39)	N19Y	probably benign	Het
Or51ai2	T	C	7: 103,587,232 (GRCm39)	V215A	probably benign	Het
Pcdh15	A	T	10: 74,460,104 (GRCm39)	I1314F	probably damaging	Het
Phf14	G	A	6: 11,962,658 (GRCm39)	S435N	probably damaging	Het
Prss45	T	A	9: 110,669,618 (GRCm39)	Y231*	probably null	Het
Pus7l	T	C	15: 94,434,449 (GRCm39)	D339G	probably damaging	Het
Sbk2	A	G	7: 4,960,408 (GRCm39)	F254S	probably damaging	Het
Serpina1b	T	G	12: 103,698,329 (GRCm39)	K173N	possibly damaging	Het
Slc13a5	G	A	11: 72,136,004 (GRCm39)	T469I	probably damaging	Het
Spon1	A	G	7: 113,633,522 (GRCm39)	E655G	probably damaging	Het
Sv2b	T	C	7: 74,806,508 (GRCm39)		probably null	Het
Treh	A	G	9: 44,597,228 (GRCm39)	D514G	probably damaging	Het
Umodl1	T	A	17: 31,215,329 (GRCm39)	L1051Q	probably damaging	Het
Usp5	A	G	6: 124,803,350 (GRCm39)	F4S	probably damaging	Het
Vmn1r16	A	G	6: 57,299,879 (GRCm39)	S248P	probably damaging	Het

Other mutations in Commd7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R1065:Commd7	UTSW	2	153,461,447 (GRCm39)	splice site	probably benign
R1131:Commd7	UTSW	2	153,464,047 (GRCm39)	missense	probably benign	0.00
R2132:Commd7	UTSW	2	153,463,586 (GRCm39)	intron	probably benign
R3897:Commd7	UTSW	2	153,464,710 (GRCm39)	missense	probably benign
R5837:Commd7	UTSW	2	153,471,144 (GRCm39)	missense	possibly damaging	0.79
R5902:Commd7	UTSW	2	153,463,737 (GRCm39)	missense	probably damaging	1.00
R6207:Commd7	UTSW	2	153,474,530 (GRCm39)	missense	possibly damaging	0.73
R9172:Commd7	UTSW	2	153,470,474 (GRCm39)	missense	possibly damaging	0.86
R9573:Commd7	UTSW	2	153,463,981 (GRCm39)	missense	probably damaging	1.00

Posted On

2016-08-02