Incidental Mutation 'IGL03411:Ogfod3'
ID421809
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ogfod3
Ensembl Gene ENSMUSG00000025169
Gene Name2-oxoglutarate and iron-dependent oxygenase domain containing 3
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.113) question?
Stock #IGL03411
Quality Score
Status
Chromosome11
Chromosomal Location121177591-121204711 bp(-) (GRCm38)
Type of Mutationmakesense
DNA Base Change (assembly) A to T at 121177804 bp
ZygosityHeterozygous
Amino Acid Change Stop codon to Arginine at position 316 (*316R)
Ref Sequence ENSEMBL: ENSMUSP00000026169 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000026169]
Predicted Effect probably null
Transcript: ENSMUST00000026169
AA Change: *316R
SMART Domains Protein: ENSMUSP00000026169
Gene: ENSMUSG00000025169
AA Change: *316R

DomainStartEndE-ValueType
transmembrane domain 39 61 N/A INTRINSIC
P4Hc 104 302 1.82e-25 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcc5 A G 16: 20,399,560 I305T probably damaging Het
Adamts18 G A 8: 113,764,297 Q513* probably null Het
Adamts6 A G 13: 104,314,334 I342V possibly damaging Het
Agtr1a A G 13: 30,381,599 T216A possibly damaging Het
Coro1b A G 19: 4,150,226 probably benign Het
Cyp4a10 G A 4: 115,525,693 probably null Het
Cyp4x1 T A 4: 115,108,785 Q448L probably benign Het
Ddx60 A T 8: 61,977,882 probably null Het
Exoc1 C A 5: 76,542,195 A194D probably damaging Het
Fastkd1 A C 2: 69,707,359 V293G probably damaging Het
Gm5773 T C 3: 93,773,957 L312P probably damaging Het
Hhla1 A G 15: 65,930,229 probably null Het
Hmcn2 A T 2: 31,346,637 E397D possibly damaging Het
Lig1 C T 7: 13,296,768 R449C probably damaging Het
Mdc1 A G 17: 35,853,126 T1189A probably benign Het
Muc4 G A 16: 32,754,318 M1397I probably benign Het
Myh15 A G 16: 49,159,967 E1484G possibly damaging Het
Neb T C 2: 52,292,878 I1019V probably benign Het
Nid1 T C 13: 13,437,889 L63P probably damaging Het
Olfr5 T C 7: 6,480,436 K240R probably benign Het
Pdpk1 A T 17: 24,101,644 V193E probably damaging Het
Phf3 G T 1: 30,804,401 P1826T probably damaging Het
Pnliprp2 A G 19: 58,760,415 I51V probably benign Het
Prpf4b C T 13: 34,895,359 L739F probably damaging Het
Rcbtb1 T A 14: 59,209,970 M1K probably null Het
Rin2 A G 2: 145,860,944 E520G probably damaging Het
Scgb2b7 A T 7: 31,705,081 C65S probably damaging Het
Shpk A G 11: 73,215,035 T238A probably benign Het
Tmem132d A T 5: 127,984,283 Y418* probably null Het
Tpte T C 8: 22,325,537 V212A possibly damaging Het
Trim55 A T 3: 19,659,190 Y135F probably damaging Het
Ttn C T 2: 76,768,112 A19486T probably damaging Het
Vmn2r59 A T 7: 42,058,916 N22K probably benign Het
Vmn2r63 T C 7: 42,927,944 D390G probably benign Het
Vmn2r96 A G 17: 18,586,372 E527G possibly damaging Het
Vps13d C T 4: 145,149,324 E1538K probably damaging Het
Zfp64 T C 2: 168,951,542 probably null Het
Zfp827 A G 8: 79,076,487 S563G probably damaging Het
Other mutations in Ogfod3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01954:Ogfod3 APN 11 121203025 missense probably benign 0.06
IGL02398:Ogfod3 APN 11 121203025 missense probably benign 0.06
IGL02458:Ogfod3 APN 11 121200923 missense probably benign 0.22
PIT4403001:Ogfod3 UTSW 11 121196735 critical splice donor site probably null
R0145:Ogfod3 UTSW 11 121195070 splice site probably benign
R1302:Ogfod3 UTSW 11 121183474 missense probably damaging 1.00
R3926:Ogfod3 UTSW 11 121183429 missense probably damaging 1.00
R4823:Ogfod3 UTSW 11 121195201 missense probably benign 0.42
R4825:Ogfod3 UTSW 11 121195201 missense probably benign 0.42
R4909:Ogfod3 UTSW 11 121197492 missense probably damaging 1.00
R6378:Ogfod3 UTSW 11 121202935 missense probably benign 0.01
R6953:Ogfod3 UTSW 11 121202998 missense probably benign
R7051:Ogfod3 UTSW 11 121195205 missense probably damaging 0.99
Posted On2016-08-02