Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03411:Ogfod3'

421809

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ogfod3

Ensembl Gene

ENSMUSG00000025169

Gene Name

2-oxoglutarate and iron-dependent oxygenase domain containing 3

Synonyms

1110031I02Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.096) question?

Stock #

IGL03411

Quality Score

Status

Chromosome

Chromosomal Location

121068419-121095474 bp(-) (GRCm39)

Type of Mutation

makesense

DNA Base Change (assembly)

A to T at 121068630 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Stop codon to Arginine at position 316 (*316R)

Ref Sequence

ENSEMBL: ENSMUSP00000026169 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000026169]

AlphaFold

Q9D136

Predicted Effect

probably null
Transcript: ENSMUST00000026169
AA Change: *316R

SMART Domains

Protein: ENSMUSP00000026169
Gene: ENSMUSG00000025169
AA Change: *316R

Domain	Start	End	E-Value	Type
transmembrane domain	39	61	N/A	INTRINSIC
P4Hc	104	302	1.82e-25	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc5	A	G	16: 20,218,310 (GRCm39)	I305T	probably damaging	Het
Adamts18	G	A	8: 114,490,929 (GRCm39)	Q513*	probably null	Het
Adamts6	A	G	13: 104,450,842 (GRCm39)	I342V	possibly damaging	Het
Agtr1a	A	G	13: 30,565,582 (GRCm39)	T216A	possibly damaging	Het
Coro1b	A	G	19: 4,200,225 (GRCm39)		probably benign	Het
Cyp4a10	G	A	4: 115,382,890 (GRCm39)		probably null	Het
Cyp4x1	T	A	4: 114,965,982 (GRCm39)	Q448L	probably benign	Het
Ddx60	A	T	8: 62,430,916 (GRCm39)		probably null	Het
Exoc1	C	A	5: 76,690,042 (GRCm39)	A194D	probably damaging	Het
Fastkd1	A	C	2: 69,537,703 (GRCm39)	V293G	probably damaging	Het
Gm5773	T	C	3: 93,681,264 (GRCm39)	L312P	probably damaging	Het
Hhla1	A	G	15: 65,802,078 (GRCm39)		probably null	Het
Hmcn2	A	T	2: 31,236,649 (GRCm39)	E397D	possibly damaging	Het
Lig1	C	T	7: 13,030,694 (GRCm39)	R449C	probably damaging	Het
Mdc1	A	G	17: 36,164,018 (GRCm39)	T1189A	probably benign	Het
Muc4	G	A	16: 32,575,436 (GRCm39)	M1397I	probably benign	Het
Myh15	A	G	16: 48,980,330 (GRCm39)	E1484G	possibly damaging	Het
Neb	T	C	2: 52,182,890 (GRCm39)	I1019V	probably benign	Het
Nid1	T	C	13: 13,612,474 (GRCm39)	L63P	probably damaging	Het
Or6z7	T	C	7: 6,483,435 (GRCm39)	K240R	probably benign	Het
Pdpk1	A	T	17: 24,320,618 (GRCm39)	V193E	probably damaging	Het
Phf3	G	T	1: 30,843,482 (GRCm39)	P1826T	probably damaging	Het
Pnliprp2	A	G	19: 58,748,847 (GRCm39)	I51V	probably benign	Het
Prpf4b	C	T	13: 35,079,342 (GRCm39)	L739F	probably damaging	Het
Rcbtb1	T	A	14: 59,447,419 (GRCm39)	M1K	probably null	Het
Rin2	A	G	2: 145,702,864 (GRCm39)	E520G	probably damaging	Het
Scgb2b7	A	T	7: 31,404,506 (GRCm39)	C65S	probably damaging	Het
Shpk	A	G	11: 73,105,861 (GRCm39)	T238A	probably benign	Het
Tmem132d	A	T	5: 128,061,347 (GRCm39)	Y418*	probably null	Het
Tpte	T	C	8: 22,815,553 (GRCm39)	V212A	possibly damaging	Het
Trim55	A	T	3: 19,713,354 (GRCm39)	Y135F	probably damaging	Het
Ttn	C	T	2: 76,598,456 (GRCm39)	A19486T	probably damaging	Het
Vmn2r59	A	T	7: 41,708,340 (GRCm39)	N22K	probably benign	Het
Vmn2r63	T	C	7: 42,577,368 (GRCm39)	D390G	probably benign	Het
Vmn2r96	A	G	17: 18,806,634 (GRCm39)	E527G	possibly damaging	Het
Vps13d	C	T	4: 144,875,894 (GRCm39)	E1538K	probably damaging	Het
Zfp64	T	C	2: 168,793,462 (GRCm39)		probably null	Het
Zfp827	A	G	8: 79,803,116 (GRCm39)	S563G	probably damaging	Het

Other mutations in Ogfod3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01954:Ogfod3	APN	11	121,093,851 (GRCm39)	missense	probably benign	0.06
IGL02398:Ogfod3	APN	11	121,093,851 (GRCm39)	missense	probably benign	0.06
IGL02458:Ogfod3	APN	11	121,091,749 (GRCm39)	missense	probably benign	0.22
PIT4403001:Ogfod3	UTSW	11	121,087,561 (GRCm39)	critical splice donor site	probably null
R0145:Ogfod3	UTSW	11	121,085,896 (GRCm39)	splice site	probably benign
R1302:Ogfod3	UTSW	11	121,074,300 (GRCm39)	missense	probably damaging	1.00
R3926:Ogfod3	UTSW	11	121,074,255 (GRCm39)	missense	probably damaging	1.00
R4823:Ogfod3	UTSW	11	121,086,027 (GRCm39)	missense	probably benign	0.42
R4825:Ogfod3	UTSW	11	121,086,027 (GRCm39)	missense	probably benign	0.42
R4909:Ogfod3	UTSW	11	121,088,318 (GRCm39)	missense	probably damaging	1.00
R6378:Ogfod3	UTSW	11	121,093,761 (GRCm39)	missense	probably benign	0.01
R6953:Ogfod3	UTSW	11	121,093,824 (GRCm39)	missense	probably benign
R7051:Ogfod3	UTSW	11	121,086,031 (GRCm39)	missense	probably damaging	0.99
R7618:Ogfod3	UTSW	11	121,093,804 (GRCm39)	missense	probably damaging	0.96
R7741:Ogfod3	UTSW	11	121,074,362 (GRCm39)	critical splice acceptor site	probably null
R8112:Ogfod3	UTSW	11	121,095,376 (GRCm39)	missense	probably damaging	1.00
R8714:Ogfod3	UTSW	11	121,087,608 (GRCm39)	missense	possibly damaging	0.79
R9769:Ogfod3	UTSW	11	121,074,357 (GRCm39)	missense	probably damaging	0.99

Posted On

2016-08-02