Incidental Mutation 'R5328:Zfp106'
| ID |
422110 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp106
|
| Ensembl Gene |
ENSMUSG00000027288 |
| Gene Name |
zinc finger protein 106 |
| Synonyms |
Cd-1, H3a, Sh3bp3, sirm |
| MMRRC Submission |
042843-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5328 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
120337301-120394324 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 120350898 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 1584
(N1584K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000128995
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055241]
[ENSMUST00000152347]
[ENSMUST00000171215]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000055241
AA Change: N1607K
PolyPhen 2
Score 0.729 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000055602
Gene: ENSMUSG00000027288
AA Change: N1607K
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
43 |
67 |
7.18e1 |
SMART |
|
low complexity region
|
75 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
141 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
199 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
466 |
480 |
N/A |
INTRINSIC |
|
coiled coil region
|
800 |
823 |
N/A |
INTRINSIC |
|
low complexity region
|
842 |
856 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1361 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1389 |
1409 |
N/A |
INTRINSIC |
|
WD40
|
1525 |
1562 |
9.24e-4 |
SMART |
|
WD40
|
1565 |
1607 |
1.83e-7 |
SMART |
|
PQQ
|
1587 |
1618 |
3.42e2 |
SMART |
|
WD40
|
1651 |
1691 |
3.45e-1 |
SMART |
|
PQQ
|
1671 |
1702 |
9.14e1 |
SMART |
|
WD40
|
1694 |
1731 |
2.12e-3 |
SMART |
|
PQQ
|
1711 |
1742 |
6.42e0 |
SMART |
|
WD40
|
1734 |
1771 |
6e-3 |
SMART |
|
PQQ
|
1751 |
1782 |
5.7e2 |
SMART |
|
WD40
|
1774 |
1811 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1818 |
1843 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1851 |
1879 |
1.31e2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139942
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152347
|
| SMART Domains |
Protein: ENSMUSP00000132902
Gene: ENSMUSG00000027288
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
66 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
115 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
143 |
163 |
N/A |
INTRINSIC |
|
Pfam:WD40
|
234 |
265 |
1.3e-5 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000171215
AA Change: N1584K
PolyPhen 2
Score 0.729 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000128995
Gene: ENSMUSG00000027288
AA Change: N1584K
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
20 |
44 |
7.18e1 |
SMART |
|
low complexity region
|
52 |
69 |
N/A |
INTRINSIC |
|
low complexity region
|
118 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
176 |
189 |
N/A |
INTRINSIC |
|
low complexity region
|
443 |
457 |
N/A |
INTRINSIC |
|
coiled coil region
|
777 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
1026 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1298 |
N/A |
INTRINSIC |
|
low complexity region
|
1338 |
1350 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1386 |
N/A |
INTRINSIC |
|
WD40
|
1502 |
1539 |
9.24e-4 |
SMART |
|
WD40
|
1542 |
1584 |
1.83e-7 |
SMART |
|
PQQ
|
1564 |
1595 |
3.42e2 |
SMART |
|
WD40
|
1628 |
1668 |
3.45e-1 |
SMART |
|
PQQ
|
1648 |
1679 |
9.14e1 |
SMART |
|
WD40
|
1671 |
1708 |
2.12e-3 |
SMART |
|
PQQ
|
1688 |
1719 |
6.42e0 |
SMART |
|
WD40
|
1711 |
1748 |
6e-3 |
SMART |
|
PQQ
|
1728 |
1759 |
5.7e2 |
SMART |
|
WD40
|
1751 |
1788 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1795 |
1820 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1828 |
1856 |
1.31e2 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit an abnormal gait, progressive motor deficits, kyphosis, weight loss, severe adult-onset degenerative sensory-motor axonopathy, mitochondrial dysfunction, and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb1b |
T |
A |
5: 8,887,694 (GRCm39) |
V860E |
possibly damaging |
Het |
| Abcc6 |
T |
C |
7: 45,641,735 (GRCm39) |
D881G |
probably benign |
Het |
| Abcc9 |
A |
G |
6: 142,627,785 (GRCm39) |
V415A |
probably benign |
Het |
| Adgrb3 |
A |
C |
1: 25,133,356 (GRCm39) |
N1003K |
possibly damaging |
Het |
| Adora3 |
C |
T |
3: 105,814,619 (GRCm39) |
T123I |
probably benign |
Het |
| Amotl2 |
A |
C |
9: 102,600,967 (GRCm39) |
T345P |
probably benign |
Het |
| Arap3 |
C |
T |
18: 38,124,740 (GRCm39) |
E247K |
possibly damaging |
Het |
| Atp8b1 |
A |
T |
18: 64,664,462 (GRCm39) |
D1235E |
probably benign |
Het |
| Axl |
A |
T |
7: 25,472,836 (GRCm39) |
V400E |
probably damaging |
Het |
| Brd8 |
T |
A |
18: 34,741,034 (GRCm39) |
N431Y |
probably benign |
Het |
| Cadps |
A |
T |
14: 12,457,790 (GRCm38) |
N1025K |
probably benign |
Het |
| Cblc |
A |
T |
7: 19,526,505 (GRCm39) |
S195T |
possibly damaging |
Het |
| Chd2 |
C |
T |
7: 73,113,429 (GRCm39) |
A1184T |
possibly damaging |
Het |
| Chst10 |
G |
A |
1: 38,935,043 (GRCm39) |
|
probably benign |
Het |
| Col12a1 |
T |
C |
9: 79,527,342 (GRCm39) |
K2663E |
probably damaging |
Het |
| Cspg4 |
A |
T |
9: 56,793,140 (GRCm39) |
I292L |
probably benign |
Het |
| Cul1 |
T |
C |
6: 47,485,251 (GRCm39) |
V294A |
probably damaging |
Het |
| Cyp2d11 |
G |
A |
15: 82,275,972 (GRCm39) |
P203L |
probably benign |
Het |
| Dnaaf10 |
C |
A |
11: 17,172,220 (GRCm39) |
P103Q |
probably damaging |
Het |
| Dscam |
T |
C |
16: 96,474,878 (GRCm39) |
H1228R |
probably benign |
Het |
| Eif3l |
A |
T |
15: 78,977,561 (GRCm39) |
K534* |
probably null |
Het |
| Enpep |
T |
C |
3: 129,074,159 (GRCm39) |
E796G |
probably benign |
Het |
| Ext1 |
C |
A |
15: 52,939,213 (GRCm39) |
W612L |
probably damaging |
Het |
| Faap100 |
T |
A |
11: 120,268,458 (GRCm39) |
E105V |
possibly damaging |
Het |
| Fam117a |
T |
A |
11: 95,254,996 (GRCm39) |
|
probably null |
Het |
| Fan1 |
A |
T |
7: 64,004,217 (GRCm39) |
Y750N |
probably damaging |
Het |
| Fat4 |
T |
A |
3: 39,011,017 (GRCm39) |
I2039N |
probably damaging |
Het |
| Gabrr2 |
G |
T |
4: 33,082,565 (GRCm39) |
D106Y |
probably damaging |
Het |
| Gak |
A |
C |
5: 108,764,867 (GRCm39) |
C145G |
possibly damaging |
Het |
| Galnt14 |
A |
T |
17: 73,812,454 (GRCm39) |
N406K |
possibly damaging |
Het |
| Gm10439 |
T |
G |
X: 148,419,159 (GRCm39) |
*434E |
probably null |
Het |
| Gm10837 |
G |
T |
14: 122,728,190 (GRCm39) |
R22L |
unknown |
Het |
| Gm19965 |
T |
A |
1: 116,749,148 (GRCm39) |
H276Q |
possibly damaging |
Het |
| Gm43517 |
T |
C |
12: 49,437,939 (GRCm39) |
|
probably benign |
Het |
| Greb1l |
A |
T |
18: 10,553,720 (GRCm39) |
I1574F |
probably damaging |
Het |
| Gzme |
G |
A |
14: 56,355,224 (GRCm39) |
H236Y |
probably benign |
Het |
| Heatr5b |
G |
A |
17: 79,133,791 (GRCm39) |
T266I |
possibly damaging |
Het |
| Hk3 |
T |
C |
13: 55,161,306 (GRCm39) |
I185V |
probably benign |
Het |
| Hnrnpr |
A |
G |
4: 136,066,527 (GRCm39) |
E302G |
probably benign |
Het |
| Itgal |
T |
C |
7: 126,910,847 (GRCm39) |
|
probably null |
Het |
| Itk |
A |
G |
11: 46,222,703 (GRCm39) |
S583P |
probably benign |
Het |
| Loxhd1 |
A |
T |
18: 77,498,268 (GRCm39) |
I1448F |
probably damaging |
Het |
| Macf1 |
GCCCCC |
GCCCCCC |
4: 123,244,784 (GRCm39) |
|
probably null |
Het |
| Man2a2 |
A |
T |
7: 80,018,504 (GRCm39) |
F118L |
probably benign |
Het |
| Mfsd5 |
T |
A |
15: 102,189,447 (GRCm39) |
V273E |
probably damaging |
Het |
| Nfe2l2 |
A |
G |
2: 75,507,200 (GRCm39) |
L300P |
probably damaging |
Het |
| Nt5c1a |
T |
G |
4: 123,102,786 (GRCm39) |
L122R |
possibly damaging |
Het |
| Nt5c3b |
A |
G |
11: 100,331,067 (GRCm39) |
F42S |
probably damaging |
Het |
| Or2av9 |
C |
A |
11: 58,381,255 (GRCm39) |
A109S |
possibly damaging |
Het |
| Or51g2 |
T |
A |
7: 102,623,175 (GRCm39) |
N8I |
possibly damaging |
Het |
| Pabpc1 |
A |
T |
15: 36,603,121 (GRCm39) |
D204E |
probably benign |
Het |
| Panx2 |
A |
G |
15: 88,952,298 (GRCm39) |
N255S |
probably damaging |
Het |
| Pcnt |
A |
G |
10: 76,247,553 (GRCm39) |
L993P |
probably damaging |
Het |
| Pfas |
A |
T |
11: 68,879,418 (GRCm39) |
C1160S |
probably damaging |
Het |
| Plekhh3 |
T |
A |
11: 101,058,484 (GRCm39) |
|
probably benign |
Het |
| Plod3 |
T |
A |
5: 137,018,537 (GRCm39) |
N258K |
probably damaging |
Het |
| Prr14l |
T |
C |
5: 32,987,365 (GRCm39) |
Q710R |
probably benign |
Het |
| Rnf216 |
G |
T |
5: 143,078,754 (GRCm39) |
T65K |
possibly damaging |
Het |
| Samd9l |
T |
C |
6: 3,376,739 (GRCm39) |
E174G |
probably damaging |
Het |
| Septin12 |
T |
A |
16: 4,811,857 (GRCm39) |
M63L |
possibly damaging |
Het |
| Sh3bgrl2 |
T |
A |
9: 83,459,509 (GRCm39) |
D22E |
probably benign |
Het |
| Sirpd |
T |
C |
3: 15,397,234 (GRCm39) |
M17V |
unknown |
Het |
| Skil |
A |
G |
3: 31,171,718 (GRCm39) |
K488R |
probably benign |
Het |
| Slamf6 |
T |
A |
1: 171,765,662 (GRCm39) |
I262K |
probably benign |
Het |
| Slc27a3 |
T |
C |
3: 90,294,139 (GRCm39) |
D470G |
probably damaging |
Het |
| Sorbs3 |
A |
T |
14: 70,418,623 (GRCm39) |
V680E |
probably damaging |
Het |
| Sox9 |
C |
T |
11: 112,673,484 (GRCm39) |
T25I |
probably benign |
Het |
| Srsf1 |
G |
T |
11: 87,940,819 (GRCm39) |
|
probably benign |
Het |
| Stard9 |
A |
C |
2: 120,529,711 (GRCm39) |
E1989D |
probably damaging |
Het |
| Thumpd2 |
T |
A |
17: 81,351,591 (GRCm39) |
I277F |
possibly damaging |
Het |
| Tinag |
C |
A |
9: 76,912,913 (GRCm39) |
G299* |
probably null |
Het |
| Tk2 |
A |
T |
8: 104,955,931 (GRCm39) |
|
probably null |
Het |
| Tmem44 |
A |
G |
16: 30,359,709 (GRCm39) |
S210P |
possibly damaging |
Het |
| Traf3ip1 |
C |
A |
1: 91,447,791 (GRCm39) |
P423T |
probably damaging |
Het |
| Trmt12 |
A |
G |
15: 58,744,704 (GRCm39) |
D34G |
probably damaging |
Het |
| Ttc39b |
A |
G |
4: 83,180,178 (GRCm39) |
Y72H |
probably damaging |
Het |
| Ttn |
G |
A |
2: 76,708,755 (GRCm39) |
|
probably benign |
Het |
| Ttyh2 |
T |
A |
11: 114,600,894 (GRCm39) |
I381N |
possibly damaging |
Het |
| Uaca |
A |
T |
9: 60,777,814 (GRCm39) |
N734Y |
probably benign |
Het |
| Usp34 |
T |
C |
11: 23,414,616 (GRCm39) |
I2853T |
probably benign |
Het |
| Usp34 |
G |
A |
11: 23,438,659 (GRCm39) |
G3407D |
probably benign |
Het |
| Vmn2r78 |
A |
G |
7: 86,570,238 (GRCm39) |
Y252C |
probably damaging |
Het |
| Wdr19 |
G |
A |
5: 65,401,522 (GRCm39) |
C979Y |
probably damaging |
Het |
| Yeats2 |
A |
T |
16: 19,989,955 (GRCm39) |
H277L |
probably damaging |
Het |
| Zbtb2 |
T |
C |
10: 4,319,267 (GRCm39) |
Y253C |
possibly damaging |
Het |
| Zfat |
C |
A |
15: 68,051,677 (GRCm39) |
G706C |
probably damaging |
Het |
|
| Other mutations in Zfp106 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00330:Zfp106
|
APN |
2 |
120,369,978 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL00816:Zfp106
|
APN |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00822:Zfp106
|
APN |
2 |
120,344,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00848:Zfp106
|
APN |
2 |
120,343,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01293:Zfp106
|
APN |
2 |
120,365,516 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01323:Zfp106
|
APN |
2 |
120,354,945 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01662:Zfp106
|
APN |
2 |
120,354,034 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01683:Zfp106
|
APN |
2 |
120,355,036 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01809:Zfp106
|
APN |
2 |
120,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01958:Zfp106
|
APN |
2 |
120,365,288 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL01960:Zfp106
|
APN |
2 |
120,369,803 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01960:Zfp106
|
APN |
2 |
120,354,524 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02168:Zfp106
|
APN |
2 |
120,364,712 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02623:Zfp106
|
APN |
2 |
120,376,395 (GRCm39) |
splice site |
probably null |
|
|
IGL02798:Zfp106
|
APN |
2 |
120,340,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02828:Zfp106
|
APN |
2 |
120,362,178 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03022:Zfp106
|
APN |
2 |
120,359,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL03308:Zfp106
|
APN |
2 |
120,354,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03324:Zfp106
|
APN |
2 |
120,365,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
lepton
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Proton
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
quark
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R0040_zfp106_031
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
string
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
theory
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0135:Zfp106
|
UTSW |
2 |
120,350,968 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0180:Zfp106
|
UTSW |
2 |
120,364,356 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0387:Zfp106
|
UTSW |
2 |
120,358,953 (GRCm39) |
splice site |
probably null |
|
|
R0558:Zfp106
|
UTSW |
2 |
120,362,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0680:Zfp106
|
UTSW |
2 |
120,357,497 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Zfp106
|
UTSW |
2 |
120,385,729 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0828:Zfp106
|
UTSW |
2 |
120,366,084 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1124:Zfp106
|
UTSW |
2 |
120,365,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1226:Zfp106
|
UTSW |
2 |
120,354,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1239:Zfp106
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1634:Zfp106
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R1754:Zfp106
|
UTSW |
2 |
120,364,245 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1754:Zfp106
|
UTSW |
2 |
120,364,244 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1755:Zfp106
|
UTSW |
2 |
120,365,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Zfp106
|
UTSW |
2 |
120,350,909 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1875:Zfp106
|
UTSW |
2 |
120,344,096 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1903:Zfp106
|
UTSW |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1932:Zfp106
|
UTSW |
2 |
120,362,162 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2070:Zfp106
|
UTSW |
2 |
120,354,010 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2301:Zfp106
|
UTSW |
2 |
120,366,131 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3429:Zfp106
|
UTSW |
2 |
120,357,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3720:Zfp106
|
UTSW |
2 |
120,365,080 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Zfp106
|
UTSW |
2 |
120,365,094 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3881:Zfp106
|
UTSW |
2 |
120,362,630 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3921:Zfp106
|
UTSW |
2 |
120,364,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3923:Zfp106
|
UTSW |
2 |
120,365,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4087:Zfp106
|
UTSW |
2 |
120,357,380 (GRCm39) |
splice site |
probably null |
|
|
R4678:Zfp106
|
UTSW |
2 |
120,364,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4965:Zfp106
|
UTSW |
2 |
120,364,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5011:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5151:Zfp106
|
UTSW |
2 |
120,365,208 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5227:Zfp106
|
UTSW |
2 |
120,354,449 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5403:Zfp106
|
UTSW |
2 |
120,365,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5624:Zfp106
|
UTSW |
2 |
120,362,438 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5686:Zfp106
|
UTSW |
2 |
120,363,988 (GRCm39) |
splice site |
probably null |
|
|
R5691:Zfp106
|
UTSW |
2 |
120,354,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5852:Zfp106
|
UTSW |
2 |
120,346,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6298:Zfp106
|
UTSW |
2 |
120,353,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6409:Zfp106
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6505:Zfp106
|
UTSW |
2 |
120,364,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6598:Zfp106
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R6765:Zfp106
|
UTSW |
2 |
120,369,935 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7013:Zfp106
|
UTSW |
2 |
120,362,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7453:Zfp106
|
UTSW |
2 |
120,376,400 (GRCm39) |
splice site |
probably null |
|
|
R7453:Zfp106
|
UTSW |
2 |
120,341,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Zfp106
|
UTSW |
2 |
120,343,215 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7829:Zfp106
|
UTSW |
2 |
120,354,538 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7897:Zfp106
|
UTSW |
2 |
120,366,096 (GRCm39) |
nonsense |
probably null |
|
|
R7909:Zfp106
|
UTSW |
2 |
120,344,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8054:Zfp106
|
UTSW |
2 |
120,355,000 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8124:Zfp106
|
UTSW |
2 |
120,354,812 (GRCm39) |
missense |
probably benign |
0.44 |
|
R8203:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8450:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8698:Zfp106
|
UTSW |
2 |
120,354,600 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8985:Zfp106
|
UTSW |
2 |
120,366,077 (GRCm39) |
missense |
|
|
|
R9015:Zfp106
|
UTSW |
2 |
120,364,019 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9036:Zfp106
|
UTSW |
2 |
120,369,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9142:Zfp106
|
UTSW |
2 |
120,350,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Zfp106
|
UTSW |
2 |
120,364,812 (GRCm39) |
nonsense |
probably null |
|
|
R9175:Zfp106
|
UTSW |
2 |
120,353,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9529:Zfp106
|
UTSW |
2 |
120,351,007 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9572:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9581:Zfp106
|
UTSW |
2 |
120,365,807 (GRCm39) |
missense |
|
|
|
RF008:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
RF025:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
X0025:Zfp106
|
UTSW |
2 |
120,365,297 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Zfp106
|
UTSW |
2 |
120,360,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTACAGCACAAAATCAGCAGATA -3'
(R):5'- ATGTGACTTTGCTTGGCAGTTAG -3'
Sequencing Primer
(F):5'- CAGCACAAAATCAGCAGATAATAATG -3'
(R):5'- CCATCTTGAACCTCAGGAATGGG -3'
|
| Posted On |
2016-08-04 |
Incidental Mutation