Mutagenetix > Incidental Mutation

Incidental Mutation 'R5340:Mroh9'

422259

Institutional Source

Beutler Lab

Gene Symbol

Mroh9

Ensembl Gene

ENSMUSG00000071890

Gene Name

maestro heat-like repeat family member 9

Synonyms

4921528O07Rik, Armc11

MMRRC Submission

042919-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5340 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

162851871-162913239 bp(-) (GRCm39)

Type of Mutation

start gained

DNA Base Change (assembly)

C to T at 162908156 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000094365 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000096608]

AlphaFold

G5E8L9

Predicted Effect

probably benign
Transcript: ENSMUST00000096608

SMART Domains

Protein: ENSMUSP00000094365
Gene: ENSMUSG00000071890

Domain	Start	End	E-Value	Type
SCOP:d1gw5b_	231	716	2e-8	SMART

Coding Region Coverage

1x: 99.4%
3x: 98.8%
10x: 97.7%
20x: 96.3%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aqp7	T	C	4: 41,034,347 (GRCm39)	R271G	probably benign	Het
Atp4a	A	G	7: 30,420,231 (GRCm39)	I793V	probably benign	Het
Baz2a	C	T	10: 127,950,911 (GRCm39)	R535C	probably damaging	Het
BC034090	T	C	1: 155,102,160 (GRCm39)	T35A	possibly damaging	Het
Bnip1	T	C	17: 27,005,764 (GRCm39)		probably null	Het
Ccdc136	A	G	6: 29,411,859 (GRCm39)	S369G	possibly damaging	Het
Csrnp3	A	G	2: 65,852,781 (GRCm39)	D391G	probably benign	Het
Ctbp2	G	T	7: 132,615,692 (GRCm39)	H414Q	probably benign	Het
Dnah6	A	G	6: 73,189,603 (GRCm39)	I15T	probably benign	Het
Dync2li1	A	G	17: 84,957,130 (GRCm39)		probably null	Het
Eri3	A	T	4: 117,530,991 (GRCm39)	I329F	probably damaging	Het
Flii	T	A	11: 60,608,094 (GRCm39)	I786F	probably damaging	Het
Fmo1	A	T	1: 162,657,551 (GRCm39)	I530N	probably benign	Het
Gm28042	T	C	2: 119,871,929 (GRCm39)	S960P	probably benign	Het
Gzmm	C	A	10: 79,530,907 (GRCm39)	F236L	probably benign	Het
H2bl1	C	T	13: 99,120,951 (GRCm39)	R25H	possibly damaging	Het
Igkv4-55	A	G	6: 69,584,489 (GRCm39)	V41A	probably damaging	Het
Ipo9	A	G	1: 135,313,170 (GRCm39)	Y1020H	probably benign	Het
Masp1	T	C	16: 23,276,858 (GRCm39)	Y549C	probably damaging	Het
Mblac1	A	T	5: 138,192,840 (GRCm39)	S61C	probably damaging	Het
Mical1	T	A	10: 41,359,427 (GRCm39)		probably null	Het
Mta2	T	C	19: 8,919,720 (GRCm39)	M1T	probably null	Het
Neb	A	G	2: 52,113,060 (GRCm39)	Y4245H	probably damaging	Het
Or11j4	T	C	14: 50,630,677 (GRCm39)	F155L	probably damaging	Het
Or4c52	T	C	2: 89,845,706 (GRCm39)	V144A	probably benign	Het
Otulinl	T	C	15: 27,658,175 (GRCm39)	M282V	possibly damaging	Het
Pak2	G	T	16: 31,853,764 (GRCm39)		probably null	Het
Phc3	A	T	3: 30,961,616 (GRCm39)	F939I	probably damaging	Het
Prss3l	T	C	6: 41,422,307 (GRCm39)	N33D	probably benign	Het
Rogdi	C	A	16: 4,831,225 (GRCm39)	R14L	probably benign	Het
Ryr3	T	C	2: 112,664,470 (GRCm39)	Y1627C	probably damaging	Het
Scrn3	A	T	2: 73,166,154 (GRCm39)	K396*	probably null	Het
Sh3pxd2a	T	C	19: 47,256,670 (GRCm39)	N683D	probably benign	Het
Smtnl1	T	A	2: 84,645,785 (GRCm39)	H362L	probably damaging	Het
Sned1	A	G	1: 93,210,479 (GRCm39)	S927G	probably benign	Het
Tcaf1	A	G	6: 42,655,923 (GRCm39)	V351A	probably damaging	Het
Tmem232	C	T	17: 65,709,993 (GRCm39)	V432M	possibly damaging	Het
Ttll11	G	T	2: 35,792,801 (GRCm39)	H347Q	probably damaging	Het
Vmn2r56	A	C	7: 12,449,799 (GRCm39)	D146E	probably damaging	Het
Wwp1	A	G	4: 19,638,773 (GRCm39)		probably null	Het
Zcchc7	T	A	4: 44,762,245 (GRCm39)	N124K	probably benign	Het
Zfp667	A	G	7: 6,308,252 (GRCm39)	T307A	possibly damaging	Het
Zfp709	T	A	8: 72,643,596 (GRCm39)	C342S	probably damaging	Het
Zfp940	A	G	7: 29,544,266 (GRCm39)	V547A	probably benign	Het

Other mutations in Mroh9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00593:Mroh9	APN	1	162,873,350 (GRCm39)	missense	possibly damaging	0.89
IGL00705:Mroh9	APN	1	162,907,072 (GRCm39)	missense	probably damaging	1.00
IGL00788:Mroh9	APN	1	162,852,227 (GRCm39)	missense	probably benign	0.06
IGL00795:Mroh9	APN	1	162,888,191 (GRCm39)	missense	probably damaging	1.00
IGL00815:Mroh9	APN	1	162,866,700 (GRCm39)	missense	probably damaging	1.00
IGL01025:Mroh9	APN	1	162,875,435 (GRCm39)	missense	possibly damaging	0.67
IGL01303:Mroh9	APN	1	162,908,144 (GRCm39)	missense	probably benign	0.00
IGL01526:Mroh9	APN	1	162,883,172 (GRCm39)	missense	probably damaging	0.99
IGL01680:Mroh9	APN	1	162,875,551 (GRCm39)	splice site	probably null
IGL01823:Mroh9	APN	1	162,883,178 (GRCm39)	missense	probably benign	0.39
IGL02024:Mroh9	APN	1	162,890,071 (GRCm39)	missense	possibly damaging	0.65
IGL02213:Mroh9	APN	1	162,885,648 (GRCm39)	missense	probably damaging	1.00
IGL02455:Mroh9	APN	1	162,903,149 (GRCm39)	missense	probably benign	0.03
IGL02546:Mroh9	APN	1	162,908,145 (GRCm39)	missense	probably benign	0.04
IGL03059:Mroh9	APN	1	162,852,205 (GRCm39)	missense	possibly damaging	0.95
IGL03061:Mroh9	APN	1	162,854,071 (GRCm39)	missense	probably damaging	1.00
IGL03071:Mroh9	APN	1	162,866,766 (GRCm39)	missense	probably damaging	1.00
R0048:Mroh9	UTSW	1	162,890,056 (GRCm39)	missense	probably damaging	0.97
R0048:Mroh9	UTSW	1	162,890,056 (GRCm39)	missense	probably damaging	0.97
R0441:Mroh9	UTSW	1	162,888,331 (GRCm39)	missense	probably damaging	1.00
R0506:Mroh9	UTSW	1	162,888,205 (GRCm39)	missense	possibly damaging	0.90
R0629:Mroh9	UTSW	1	162,888,205 (GRCm39)	missense	possibly damaging	0.90
R0751:Mroh9	UTSW	1	162,893,693 (GRCm39)	missense	possibly damaging	0.84
R1301:Mroh9	UTSW	1	162,871,552 (GRCm39)	critical splice donor site	probably null
R1481:Mroh9	UTSW	1	162,854,078 (GRCm39)	missense	probably damaging	1.00
R1618:Mroh9	UTSW	1	162,852,110 (GRCm39)	missense	probably benign	0.00
R1647:Mroh9	UTSW	1	162,873,625 (GRCm39)	missense	probably damaging	1.00
R1648:Mroh9	UTSW	1	162,873,625 (GRCm39)	missense	probably damaging	1.00
R1668:Mroh9	UTSW	1	162,852,161 (GRCm39)	missense	possibly damaging	0.52
R1795:Mroh9	UTSW	1	162,884,347 (GRCm39)	missense	probably damaging	0.97
R1796:Mroh9	UTSW	1	162,873,279 (GRCm39)	missense	probably damaging	1.00
R1857:Mroh9	UTSW	1	162,866,714 (GRCm39)	missense	probably damaging	0.98
R1869:Mroh9	UTSW	1	162,854,082 (GRCm39)	missense	probably damaging	0.97
R1923:Mroh9	UTSW	1	162,903,860 (GRCm39)	missense	probably damaging	1.00
R2325:Mroh9	UTSW	1	162,854,099 (GRCm39)	splice site	probably null
R2511:Mroh9	UTSW	1	162,866,514 (GRCm39)	missense	probably benign	0.13
R2912:Mroh9	UTSW	1	162,871,572 (GRCm39)	missense	probably damaging	1.00
R2913:Mroh9	UTSW	1	162,871,572 (GRCm39)	missense	probably damaging	1.00
R2919:Mroh9	UTSW	1	162,884,341 (GRCm39)	missense	probably damaging	1.00
R2973:Mroh9	UTSW	1	162,884,338 (GRCm39)	missense	probably damaging	1.00
R3912:Mroh9	UTSW	1	162,893,638 (GRCm39)	missense	probably damaging	0.97
R4034:Mroh9	UTSW	1	162,908,122 (GRCm39)	critical splice donor site	probably null
R4551:Mroh9	UTSW	1	162,871,662 (GRCm39)	missense	probably damaging	0.98
R4656:Mroh9	UTSW	1	162,893,593 (GRCm39)	missense	probably damaging	1.00
R4662:Mroh9	UTSW	1	162,883,162 (GRCm39)	missense	probably damaging	0.97
R4743:Mroh9	UTSW	1	162,852,061 (GRCm39)	missense	probably benign	0.05
R4890:Mroh9	UTSW	1	162,854,093 (GRCm39)	missense	probably damaging	1.00
R5128:Mroh9	UTSW	1	162,888,329 (GRCm39)	missense	probably damaging	1.00
R5129:Mroh9	UTSW	1	162,888,329 (GRCm39)	missense	probably damaging	1.00
R5147:Mroh9	UTSW	1	162,888,329 (GRCm39)	missense	probably damaging	1.00
R5157:Mroh9	UTSW	1	162,871,690 (GRCm39)	missense	probably damaging	0.96
R5324:Mroh9	UTSW	1	162,888,329 (GRCm39)	missense	probably damaging	1.00
R5325:Mroh9	UTSW	1	162,888,329 (GRCm39)	missense	probably damaging	1.00
R6005:Mroh9	UTSW	1	162,903,246 (GRCm39)	missense	probably damaging	0.99
R6182:Mroh9	UTSW	1	162,893,612 (GRCm39)	nonsense	probably null
R6414:Mroh9	UTSW	1	162,902,271 (GRCm39)	missense	probably damaging	1.00
R6477:Mroh9	UTSW	1	162,903,873 (GRCm39)	missense	probably damaging	1.00
R6540:Mroh9	UTSW	1	162,866,541 (GRCm39)	missense	possibly damaging	0.87
R6541:Mroh9	UTSW	1	162,885,607 (GRCm39)	missense	possibly damaging	0.78
R6643:Mroh9	UTSW	1	162,903,130 (GRCm39)	missense	probably damaging	1.00
R6811:Mroh9	UTSW	1	162,873,610 (GRCm39)	missense	possibly damaging	0.86
R6830:Mroh9	UTSW	1	162,903,935 (GRCm39)	missense	probably benign
R7026:Mroh9	UTSW	1	162,888,251 (GRCm39)	missense	probably benign	0.00
R7052:Mroh9	UTSW	1	162,866,525 (GRCm39)	missense	possibly damaging	0.92
R7068:Mroh9	UTSW	1	162,866,750 (GRCm39)	missense	probably damaging	1.00
R7350:Mroh9	UTSW	1	162,903,858 (GRCm39)	critical splice donor site	probably null
R7545:Mroh9	UTSW	1	162,902,277 (GRCm39)	missense	possibly damaging	0.56
R7615:Mroh9	UTSW	1	162,873,601 (GRCm39)	missense	probably benign	0.40
R7743:Mroh9	UTSW	1	162,852,122 (GRCm39)	missense	probably benign
R7808:Mroh9	UTSW	1	162,866,678 (GRCm39)	missense	probably damaging	1.00
R8024:Mroh9	UTSW	1	162,866,802 (GRCm39)	missense	probably benign	0.02
R8062:Mroh9	UTSW	1	162,866,544 (GRCm39)	missense	probably damaging	1.00
R8145:Mroh9	UTSW	1	162,890,096 (GRCm39)	missense	probably benign	0.00
R8426:Mroh9	UTSW	1	162,852,294 (GRCm39)	missense	probably damaging	0.98
R8458:Mroh9	UTSW	1	162,883,250 (GRCm39)	missense	probably damaging	1.00
R8555:Mroh9	UTSW	1	162,899,595 (GRCm39)	splice site	probably null
R8960:Mroh9	UTSW	1	162,883,196 (GRCm39)	missense	probably benign	0.25
R9040:Mroh9	UTSW	1	162,890,069 (GRCm39)	missense	probably benign	0.06
R9125:Mroh9	UTSW	1	162,875,412 (GRCm39)	missense	probably benign	0.19
R9154:Mroh9	UTSW	1	162,890,030 (GRCm39)	missense
R9596:Mroh9	UTSW	1	162,893,576 (GRCm39)	missense	probably damaging	0.98
R9612:Mroh9	UTSW	1	162,866,498 (GRCm39)	missense	probably damaging	1.00
RF003:Mroh9	UTSW	1	162,885,630 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

Posted On

2016-08-04