Incidental Mutation 'R5364:Epha7'
| ID |
422984 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Epha7
|
| Ensembl Gene |
ENSMUSG00000028289 |
| Gene Name |
Eph receptor A7 |
| Synonyms |
Ehk3, MDK1, Cek11, Mdk1, Hek11, Ebk |
| MMRRC Submission |
042942-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.501)
|
| Stock # |
R5364 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
28813131-28967499 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 28950557 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Asparagine
at position 791
(Y791N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000029964
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029964]
[ENSMUST00000080934]
[ENSMUST00000108191]
[ENSMUST00000108194]
|
| AlphaFold |
Q61772 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000029964
AA Change: Y791N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000029964
Gene: ENSMUSG00000028289
AA Change: Y791N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
EPH_lbd
|
32 |
205 |
3.24e-126 |
SMART |
|
FN3
|
332 |
422 |
2.39e-8 |
SMART |
|
FN3
|
443 |
524 |
3.12e-12 |
SMART |
|
Pfam:EphA2_TM
|
557 |
630 |
4.4e-25 |
PFAM |
|
TyrKc
|
633 |
890 |
8.84e-139 |
SMART |
|
SAM
|
920 |
987 |
1.26e-23 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000080934
|
| SMART Domains |
Protein: ENSMUSP00000079735
Gene: ENSMUSG00000028289
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
EPH_lbd
|
32 |
205 |
3.24e-126 |
SMART |
|
FN3
|
332 |
422 |
2.39e-8 |
SMART |
|
FN3
|
443 |
524 |
3.12e-12 |
SMART |
|
transmembrane domain
|
556 |
578 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108191
AA Change: Y787N
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000103826
Gene: ENSMUSG00000028289
AA Change: Y787N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
EPH_lbd
|
32 |
205 |
3.24e-126 |
SMART |
|
FN3
|
332 |
422 |
2.39e-8 |
SMART |
|
FN3
|
443 |
524 |
3.12e-12 |
SMART |
|
Pfam:EphA2_TM
|
556 |
626 |
2.9e-23 |
PFAM |
|
TyrKc
|
629 |
886 |
8.84e-139 |
SMART |
|
SAM
|
916 |
983 |
1.26e-23 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108194
|
| SMART Domains |
Protein: ENSMUSP00000103829
Gene: ENSMUSG00000028289
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
EPH_lbd
|
32 |
205 |
3.24e-126 |
SMART |
|
FN3
|
332 |
422 |
2.39e-8 |
SMART |
|
FN3
|
443 |
524 |
3.12e-12 |
SMART |
|
transmembrane domain
|
556 |
578 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129912
|
| Meta Mutation Damage Score |
0.8675 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.8%
- 10x: 97.6%
- 20x: 96.3%
|
| Validation Efficiency |
100% (102/102) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
PHENOTYPE: Some homozygous mutants display anencephaly. Mutants also exhibit increased proliferation of neural progenitor cells in the lateral ventricle wall of the adult brain. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310022A10Rik |
C |
G |
7: 27,278,192 (GRCm39) |
T242R |
probably damaging |
Het |
| Abcc10 |
G |
A |
17: 46,616,577 (GRCm39) |
R1205C |
probably benign |
Het |
| Acer1 |
A |
G |
17: 57,289,000 (GRCm39) |
F37L |
probably damaging |
Het |
| Acp7 |
C |
A |
7: 28,310,448 (GRCm39) |
G463V |
probably benign |
Het |
| Actr2 |
A |
T |
11: 20,050,797 (GRCm39) |
|
probably benign |
Het |
| Adam15 |
A |
T |
3: 89,252,902 (GRCm39) |
I272K |
probably damaging |
Het |
| Adam1b |
T |
A |
5: 121,638,946 (GRCm39) |
I700F |
possibly damaging |
Het |
| Adam33 |
A |
G |
2: 130,896,392 (GRCm39) |
|
probably null |
Het |
| Ano1 |
T |
C |
7: 144,190,941 (GRCm39) |
Y380C |
probably damaging |
Het |
| Arfgap3 |
A |
C |
15: 83,198,562 (GRCm39) |
M307R |
probably damaging |
Het |
| Arhgap21 |
T |
A |
2: 20,854,533 (GRCm39) |
R1610W |
probably damaging |
Het |
| Bbs2 |
A |
G |
8: 94,801,023 (GRCm39) |
Y603H |
probably benign |
Het |
| Bbs9 |
G |
T |
9: 22,486,492 (GRCm39) |
|
probably null |
Het |
| Bcar3 |
A |
C |
3: 122,323,281 (GRCm39) |
M779L |
probably benign |
Het |
| Bub3 |
A |
T |
7: 131,162,467 (GRCm39) |
N10I |
possibly damaging |
Het |
| Cacna1c |
T |
G |
6: 118,633,504 (GRCm39) |
E1098D |
probably benign |
Het |
| Cacna1g |
T |
A |
11: 94,307,684 (GRCm39) |
M1738L |
probably benign |
Het |
| Camk2d |
G |
T |
3: 126,574,069 (GRCm39) |
G159C |
probably damaging |
Het |
| Ccdc51 |
A |
T |
9: 108,921,188 (GRCm39) |
E358D |
possibly damaging |
Het |
| Cdc42bpa |
A |
G |
1: 179,894,747 (GRCm39) |
D309G |
probably benign |
Het |
| Cdhr3 |
A |
T |
12: 33,101,007 (GRCm39) |
F468I |
possibly damaging |
Het |
| Chrd |
A |
G |
16: 20,551,898 (GRCm39) |
M1V |
probably null |
Het |
| Cmtm1 |
CGGCACGTACTGAAGGTCGCTGACTGGATGGTGTGGCACGTACTGAAGGTCGCTGACTGGATGGTGTGGCACGTACTGAAGGTCGCTGACTGGATGGT |
CGGCACGTACTGAAGGTCGCTGACTGGATGGTGTGGCACGTACTGAAGGTCGCTGACTGGATGGT |
8: 105,036,102 (GRCm39) |
|
probably benign |
Het |
| Dcdc2b |
T |
C |
4: 129,502,963 (GRCm39) |
Y253C |
probably damaging |
Het |
| Dclk1 |
A |
C |
3: 55,163,366 (GRCm39) |
N153H |
possibly damaging |
Het |
| Dgkg |
G |
T |
16: 22,419,211 (GRCm39) |
S96R |
probably benign |
Het |
| Dnah9 |
A |
G |
11: 65,772,522 (GRCm39) |
Y3737H |
possibly damaging |
Het |
| Elovl4 |
A |
T |
9: 83,672,076 (GRCm39) |
I81N |
probably benign |
Het |
| Fam193a |
C |
A |
5: 34,623,597 (GRCm39) |
T1395N |
probably benign |
Het |
| Fbln5 |
A |
T |
12: 101,737,623 (GRCm39) |
V141E |
probably damaging |
Het |
| Flii |
T |
C |
11: 60,610,954 (GRCm39) |
T492A |
probably benign |
Het |
| Fnip2 |
A |
G |
3: 79,388,475 (GRCm39) |
I752T |
probably benign |
Het |
| Fpr3 |
T |
C |
17: 18,190,806 (GRCm39) |
W26R |
probably benign |
Het |
| Gabrb1 |
A |
T |
5: 72,294,105 (GRCm39) |
T460S |
probably benign |
Het |
| Gde1 |
T |
C |
7: 118,297,874 (GRCm39) |
N4S |
probably benign |
Het |
| Ghitm |
G |
T |
14: 36,847,156 (GRCm39) |
T306K |
probably benign |
Het |
| Ghitm |
A |
T |
14: 36,847,174 (GRCm39) |
I300N |
probably damaging |
Het |
| Gm4787 |
G |
C |
12: 81,424,604 (GRCm39) |
T518S |
probably benign |
Het |
| Iqcd |
T |
C |
5: 120,738,332 (GRCm39) |
I50T |
probably damaging |
Het |
| Itpripl1 |
G |
A |
2: 126,983,739 (GRCm39) |
P128S |
possibly damaging |
Het |
| Jag2 |
C |
A |
12: 112,874,154 (GRCm39) |
L1000F |
probably damaging |
Het |
| Klhdc4 |
A |
T |
8: 122,533,375 (GRCm39) |
|
probably benign |
Het |
| Klra5 |
A |
G |
6: 129,876,316 (GRCm39) |
F164L |
probably benign |
Het |
| Larp1b |
A |
G |
3: 40,931,658 (GRCm39) |
Y288C |
probably damaging |
Het |
| Lrfn3 |
T |
A |
7: 30,055,078 (GRCm39) |
E622D |
possibly damaging |
Het |
| Lyst |
A |
G |
13: 13,831,439 (GRCm39) |
D1621G |
probably benign |
Het |
| Mastl |
T |
C |
2: 23,023,665 (GRCm39) |
T353A |
probably benign |
Het |
| Mkln1 |
T |
C |
6: 31,473,647 (GRCm39) |
Y130H |
probably damaging |
Het |
| Mms22l |
T |
A |
4: 24,496,882 (GRCm39) |
|
probably benign |
Het |
| Mroh7 |
T |
A |
4: 106,548,840 (GRCm39) |
M1008L |
probably benign |
Het |
| Nipal1 |
T |
C |
5: 72,825,243 (GRCm39) |
V312A |
probably damaging |
Het |
| Nlrp5 |
T |
A |
7: 23,117,753 (GRCm39) |
Y492* |
probably null |
Het |
| Odad1 |
T |
A |
7: 45,585,756 (GRCm39) |
I105N |
probably damaging |
Het |
| Or1n1 |
T |
C |
2: 36,750,006 (GRCm39) |
Y118C |
probably damaging |
Het |
| Otulinl |
G |
A |
15: 27,660,031 (GRCm39) |
Q24* |
probably null |
Het |
| Pcdhb11 |
T |
A |
18: 37,555,232 (GRCm39) |
D187E |
probably benign |
Het |
| Pcdhb13 |
A |
G |
18: 37,576,561 (GRCm39) |
Y313C |
probably damaging |
Het |
| Pdpn |
G |
A |
4: 143,000,526 (GRCm39) |
T102I |
possibly damaging |
Het |
| Pear1 |
A |
T |
3: 87,665,668 (GRCm39) |
C120S |
probably damaging |
Het |
| Peg10 |
T |
C |
6: 4,756,128 (GRCm39) |
|
probably benign |
Het |
| Ppm1e |
A |
G |
11: 87,128,007 (GRCm39) |
W384R |
probably benign |
Het |
| Ppp1r10 |
C |
T |
17: 36,241,324 (GRCm39) |
P700S |
unknown |
Het |
| Prl2c5 |
G |
A |
13: 13,357,627 (GRCm39) |
R13K |
probably benign |
Het |
| Prmt3 |
C |
A |
7: 49,498,554 (GRCm39) |
P487T |
probably damaging |
Het |
| Proser3 |
C |
A |
7: 30,245,573 (GRCm39) |
A144S |
possibly damaging |
Het |
| Ptcd1 |
G |
A |
5: 145,088,241 (GRCm39) |
T590I |
probably damaging |
Het |
| Rbsn |
A |
G |
6: 92,170,958 (GRCm39) |
V321A |
probably damaging |
Het |
| Slc40a1 |
C |
A |
1: 45,964,383 (GRCm39) |
C14F |
probably damaging |
Het |
| Slc6a15 |
T |
C |
10: 103,229,369 (GRCm39) |
I136T |
probably damaging |
Het |
| Slc7a4 |
A |
G |
16: 17,391,227 (GRCm39) |
I449T |
probably benign |
Het |
| Snrnp48 |
T |
A |
13: 38,394,165 (GRCm39) |
|
probably null |
Het |
| Tada2a |
A |
G |
11: 84,011,973 (GRCm39) |
Y23H |
probably benign |
Het |
| Tbx15 |
A |
T |
3: 99,259,508 (GRCm39) |
S460C |
possibly damaging |
Het |
| Tbx21 |
C |
T |
11: 96,992,304 (GRCm39) |
|
probably null |
Het |
| Tmcc2 |
T |
G |
1: 132,285,534 (GRCm39) |
T376P |
probably damaging |
Het |
| Tmco4 |
G |
A |
4: 138,779,815 (GRCm39) |
C420Y |
probably damaging |
Het |
| Tmem235 |
C |
A |
11: 117,755,020 (GRCm39) |
Y157* |
probably null |
Het |
| Tmem63b |
T |
C |
17: 45,975,653 (GRCm39) |
|
probably benign |
Het |
| Tnfrsf1a |
T |
C |
6: 125,334,356 (GRCm39) |
S92P |
possibly damaging |
Het |
| Top3b |
A |
T |
16: 16,704,834 (GRCm39) |
T397S |
probably benign |
Het |
| Trabd |
C |
A |
15: 88,967,007 (GRCm39) |
|
probably benign |
Het |
| Trbv21 |
A |
T |
6: 41,179,764 (GRCm39) |
I27L |
possibly damaging |
Het |
| Trim3 |
C |
T |
7: 105,268,276 (GRCm39) |
V169M |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,807,458 (GRCm39) |
T92A |
probably damaging |
Het |
| Ttn |
C |
T |
2: 76,738,860 (GRCm39) |
S3893N |
probably benign |
Het |
| Uchl4 |
A |
T |
9: 64,142,821 (GRCm39) |
I101F |
possibly damaging |
Het |
| Vmn1r5 |
T |
A |
6: 56,962,583 (GRCm39) |
M86K |
probably damaging |
Het |
| Vmn2r55 |
T |
A |
7: 12,404,830 (GRCm39) |
Q191L |
possibly damaging |
Het |
| Zfp458 |
A |
T |
13: 67,406,012 (GRCm39) |
C139* |
probably null |
Het |
| Zfp788 |
T |
C |
7: 41,299,551 (GRCm39) |
L729P |
probably damaging |
Het |
| Zmym2 |
T |
A |
14: 57,158,102 (GRCm39) |
M547K |
possibly damaging |
Het |
|
| Other mutations in Epha7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00811:Epha7
|
APN |
4 |
28,961,285 (GRCm39) |
intron |
probably benign |
|
|
IGL00849:Epha7
|
APN |
4 |
28,870,662 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL00898:Epha7
|
APN |
4 |
28,938,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02036:Epha7
|
APN |
4 |
28,950,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02227:Epha7
|
APN |
4 |
28,821,587 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02237:Epha7
|
APN |
4 |
28,949,325 (GRCm39) |
splice site |
probably null |
|
|
IGL02376:Epha7
|
APN |
4 |
28,951,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02424:Epha7
|
APN |
4 |
28,948,790 (GRCm39) |
intron |
probably benign |
|
|
IGL02519:Epha7
|
APN |
4 |
28,821,494 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02522:Epha7
|
APN |
4 |
28,821,494 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02524:Epha7
|
APN |
4 |
28,821,494 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02602:Epha7
|
APN |
4 |
28,871,877 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
Pump
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
PIT4514001:Epha7
|
UTSW |
4 |
28,961,355 (GRCm39) |
nonsense |
probably null |
|
|
R0001:Epha7
|
UTSW |
4 |
28,961,279 (GRCm39) |
intron |
probably benign |
|
|
R0011:Epha7
|
UTSW |
4 |
28,962,564 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0011:Epha7
|
UTSW |
4 |
28,962,564 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0310:Epha7
|
UTSW |
4 |
28,961,301 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0373:Epha7
|
UTSW |
4 |
28,935,700 (GRCm39) |
splice site |
probably null |
|
|
R0496:Epha7
|
UTSW |
4 |
28,821,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0554:Epha7
|
UTSW |
4 |
28,951,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0632:Epha7
|
UTSW |
4 |
28,821,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1677:Epha7
|
UTSW |
4 |
28,947,571 (GRCm39) |
nonsense |
probably null |
|
|
R1883:Epha7
|
UTSW |
4 |
28,950,362 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1919:Epha7
|
UTSW |
4 |
28,963,969 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1952:Epha7
|
UTSW |
4 |
28,950,474 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1999:Epha7
|
UTSW |
4 |
28,938,686 (GRCm39) |
nonsense |
probably null |
|
|
R2187:Epha7
|
UTSW |
4 |
28,942,648 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R2308:Epha7
|
UTSW |
4 |
28,821,503 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2417:Epha7
|
UTSW |
4 |
28,947,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3911:Epha7
|
UTSW |
4 |
28,938,680 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4350:Epha7
|
UTSW |
4 |
28,950,393 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4688:Epha7
|
UTSW |
4 |
28,821,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4702:Epha7
|
UTSW |
4 |
28,961,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4957:Epha7
|
UTSW |
4 |
28,871,892 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5661:Epha7
|
UTSW |
4 |
28,946,217 (GRCm39) |
splice site |
probably null |
|
|
R5820:Epha7
|
UTSW |
4 |
28,949,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6038:Epha7
|
UTSW |
4 |
28,821,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6038:Epha7
|
UTSW |
4 |
28,821,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6592:Epha7
|
UTSW |
4 |
28,813,482 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6783:Epha7
|
UTSW |
4 |
28,950,528 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6991:Epha7
|
UTSW |
4 |
28,821,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7152:Epha7
|
UTSW |
4 |
28,935,826 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7232:Epha7
|
UTSW |
4 |
28,951,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7261:Epha7
|
UTSW |
4 |
28,813,418 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7365:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7367:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7368:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7413:Epha7
|
UTSW |
4 |
28,871,838 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7603:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7604:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7605:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7607:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7608:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7609:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7610:Epha7
|
UTSW |
4 |
28,871,937 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8073:Epha7
|
UTSW |
4 |
28,821,022 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8263:Epha7
|
UTSW |
4 |
28,821,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8334:Epha7
|
UTSW |
4 |
28,938,777 (GRCm39) |
missense |
probably benign |
0.26 |
|
R8866:Epha7
|
UTSW |
4 |
28,821,614 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8906:Epha7
|
UTSW |
4 |
28,821,615 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8914:Epha7
|
UTSW |
4 |
28,963,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9335:Epha7
|
UTSW |
4 |
28,966,529 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9355:Epha7
|
UTSW |
4 |
28,935,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9576:Epha7
|
UTSW |
4 |
28,870,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9796:Epha7
|
UTSW |
4 |
28,817,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGATGGGCAGTTTACAGTCATTC -3'
(R):5'- GTCCAGACAGTGAAACACCAGG -3'
Sequencing Primer
(F):5'- ACAGTCATTCAGTTGGTAGGAATG -3'
(R):5'- CACCAGGGTAAGATGTAACATTAC -3'
|
| Posted On |
2016-08-04 |
Incidental Mutation