Incidental Mutation 'R5426:Arap2'
| ID |
426872 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap2
|
| Ensembl Gene |
ENSMUSG00000037999 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| Synonyms |
Centd1 |
| MMRRC Submission |
042992-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5426 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
62759788-62923502 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 62800159 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 1289
(N1289K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000075924
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000076623]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000076623
AA Change: N1289K
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000075924
Gene: ENSMUSG00000037999
AA Change: N1289K
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
3.69e-7 |
SMART |
|
low complexity region
|
222 |
233 |
N/A |
INTRINSIC |
|
PH
|
481 |
574 |
6.45e-17 |
SMART |
|
PH
|
586 |
679 |
9.05e-12 |
SMART |
|
ArfGap
|
684 |
805 |
9.2e-33 |
SMART |
|
PH
|
891 |
1003 |
1.51e-8 |
SMART |
|
PH
|
1013 |
1112 |
9.21e-4 |
SMART |
|
RhoGAP
|
1124 |
1300 |
1.36e-50 |
SMART |
|
Pfam:RA
|
1325 |
1416 |
2.1e-7 |
PFAM |
|
PH
|
1429 |
1533 |
2.68e-14 |
SMART |
|
coiled coil region
|
1561 |
1590 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000160419
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200549
|
| Meta Mutation Damage Score |
0.0700 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
97% (85/88) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2010315B03Rik |
T |
A |
9: 124,056,633 (GRCm39) |
H122L |
probably damaging |
Het |
| 9330182O14Rik |
G |
A |
15: 40,011,932 (GRCm39) |
M90I |
unknown |
Het |
| 9330182O14Rik |
G |
A |
15: 40,011,933 (GRCm39) |
D91N |
unknown |
Het |
| Abca13 |
T |
A |
11: 9,240,722 (GRCm39) |
S862T |
probably damaging |
Het |
| Acyp2 |
C |
T |
11: 30,456,354 (GRCm39) |
E98K |
possibly damaging |
Het |
| Adgb |
C |
A |
10: 10,226,004 (GRCm39) |
A1405S |
probably benign |
Het |
| Adpgk |
T |
A |
9: 59,204,832 (GRCm39) |
V86E |
probably damaging |
Het |
| Agfg2 |
G |
C |
5: 137,666,020 (GRCm39) |
P80A |
probably damaging |
Het |
| Akap11 |
G |
A |
14: 78,736,304 (GRCm39) |
Q1829* |
probably null |
Het |
| Aldh1l1 |
G |
A |
6: 90,536,281 (GRCm39) |
R62Q |
probably benign |
Het |
| Amd1 |
G |
T |
10: 40,166,183 (GRCm39) |
D265E |
probably damaging |
Het |
| Aox4 |
A |
T |
1: 58,259,253 (GRCm39) |
Q106L |
probably damaging |
Het |
| Arhgef12 |
T |
C |
9: 42,897,880 (GRCm39) |
S874G |
probably damaging |
Het |
| Ccdc166 |
T |
C |
15: 75,853,945 (GRCm39) |
Q45R |
possibly damaging |
Het |
| Cdc45 |
C |
T |
16: 18,614,647 (GRCm39) |
R205H |
probably damaging |
Het |
| Cdk14 |
A |
G |
5: 4,938,975 (GRCm39) |
S388P |
possibly damaging |
Het |
| Chgb |
A |
T |
2: 132,635,453 (GRCm39) |
Q465L |
possibly damaging |
Het |
| Commd9 |
T |
A |
2: 101,729,220 (GRCm39) |
W109R |
probably damaging |
Het |
| Cspg4b |
G |
A |
13: 113,505,587 (GRCm39) |
V2239I |
probably benign |
Het |
| Cyp2b9 |
T |
C |
7: 25,887,080 (GRCm39) |
V163A |
probably benign |
Het |
| Dcpp2 |
T |
A |
17: 24,118,287 (GRCm39) |
H27Q |
possibly damaging |
Het |
| Ddn |
T |
A |
15: 98,704,347 (GRCm39) |
E315V |
possibly damaging |
Het |
| Defb29 |
C |
A |
2: 152,380,868 (GRCm39) |
C47F |
probably damaging |
Het |
| Dnah7b |
T |
C |
1: 46,281,366 (GRCm39) |
M2809T |
possibly damaging |
Het |
| Dock4 |
A |
T |
12: 40,795,744 (GRCm39) |
I854F |
probably damaging |
Het |
| Dsg4 |
T |
C |
18: 20,591,541 (GRCm39) |
Y427H |
probably damaging |
Het |
| E130114P18Rik |
C |
T |
4: 97,578,907 (GRCm39) |
A23T |
unknown |
Het |
| Flacc1 |
T |
A |
1: 58,706,045 (GRCm39) |
K275* |
probably null |
Het |
| Gemin5 |
A |
G |
11: 58,016,113 (GRCm39) |
S1297P |
probably benign |
Het |
| Gm10309 |
A |
C |
17: 86,806,161 (GRCm39) |
|
probably benign |
Het |
| Gpatch11 |
T |
A |
17: 79,148,663 (GRCm39) |
S155R |
possibly damaging |
Het |
| Grin2b |
C |
A |
6: 135,709,366 (GRCm39) |
Q1393H |
probably damaging |
Het |
| Heatr5b |
C |
T |
17: 79,081,142 (GRCm39) |
C1370Y |
probably damaging |
Het |
| Hmcn2 |
C |
T |
2: 31,226,556 (GRCm39) |
T177I |
possibly damaging |
Het |
| Ildr1 |
A |
T |
16: 36,529,981 (GRCm39) |
I123F |
probably damaging |
Het |
| Kalrn |
A |
T |
16: 34,083,023 (GRCm39) |
V644D |
probably damaging |
Het |
| Kifap3 |
A |
G |
1: 163,607,440 (GRCm39) |
M1V |
probably null |
Het |
| Klhl11 |
A |
G |
11: 100,354,942 (GRCm39) |
L293P |
probably damaging |
Het |
| Klrc3 |
G |
A |
6: 129,618,513 (GRCm39) |
S98L |
probably benign |
Het |
| Lrrc37 |
A |
T |
11: 103,511,586 (GRCm39) |
H127Q |
unknown |
Het |
| Med12l |
G |
A |
3: 59,156,143 (GRCm39) |
M1220I |
probably damaging |
Het |
| Ms4a7 |
C |
T |
19: 11,303,166 (GRCm39) |
|
probably null |
Het |
| Mybpc2 |
A |
G |
7: 44,159,253 (GRCm39) |
V599A |
probably benign |
Het |
| Naalad2 |
T |
C |
9: 18,258,815 (GRCm39) |
N487D |
probably benign |
Het |
| Nat8f7 |
T |
G |
6: 85,684,805 (GRCm39) |
S12R |
probably benign |
Het |
| Nefm |
T |
A |
14: 68,357,515 (GRCm39) |
|
probably benign |
Het |
| Nlrp5 |
T |
C |
7: 23,117,626 (GRCm39) |
V450A |
probably damaging |
Het |
| Nps |
G |
A |
7: 134,870,376 (GRCm39) |
|
probably null |
Het |
| Or13c7d |
A |
G |
4: 43,770,168 (GRCm39) |
I281T |
probably benign |
Het |
| Or2ag16 |
C |
A |
7: 106,351,773 (GRCm39) |
S274I |
probably benign |
Het |
| Or4a74 |
T |
C |
2: 89,440,083 (GRCm39) |
Y121C |
probably damaging |
Het |
| Or4b13 |
T |
A |
2: 90,082,955 (GRCm39) |
K126* |
probably null |
Het |
| Or5e1 |
T |
C |
7: 108,354,924 (GRCm39) |
L287P |
possibly damaging |
Het |
| Or5h24 |
G |
T |
16: 58,918,665 (GRCm39) |
P230Q |
possibly damaging |
Het |
| Or5p67 |
T |
C |
7: 107,922,017 (GRCm39) |
N289D |
probably damaging |
Het |
| Oxct2a |
C |
A |
4: 123,216,506 (GRCm39) |
G292W |
possibly damaging |
Het |
| Pramel32 |
T |
A |
4: 88,547,647 (GRCm39) |
|
probably benign |
Het |
| Prr27 |
T |
C |
5: 87,998,744 (GRCm39) |
|
probably benign |
Het |
| Ptx3 |
T |
C |
3: 66,128,143 (GRCm39) |
M68T |
probably damaging |
Het |
| Rufy1 |
A |
G |
11: 50,312,561 (GRCm39) |
L131S |
probably damaging |
Het |
| Septin7 |
T |
A |
9: 25,197,986 (GRCm39) |
I100N |
possibly damaging |
Het |
| Sgms2 |
T |
C |
3: 131,135,446 (GRCm39) |
I143V |
probably benign |
Het |
| Slc25a34 |
A |
G |
4: 141,350,877 (GRCm39) |
V44A |
probably damaging |
Het |
| Slc28a3 |
T |
A |
13: 58,710,968 (GRCm39) |
D518V |
probably damaging |
Het |
| Slc6a7 |
C |
T |
18: 61,136,308 (GRCm39) |
|
probably null |
Het |
| Slco4a1 |
C |
A |
2: 180,113,028 (GRCm39) |
A420D |
possibly damaging |
Het |
| Smap1 |
T |
C |
1: 23,888,471 (GRCm39) |
T180A |
probably benign |
Het |
| Specc1l |
T |
C |
10: 75,103,384 (GRCm39) |
S920P |
probably benign |
Het |
| Tgtp2 |
A |
G |
11: 48,950,083 (GRCm39) |
M163T |
probably benign |
Het |
| Tiam1 |
G |
T |
16: 89,662,280 (GRCm39) |
Q613K |
possibly damaging |
Het |
| Vsig10l |
T |
A |
7: 43,114,247 (GRCm39) |
S190T |
probably damaging |
Het |
| Vwa3b |
A |
G |
1: 37,154,752 (GRCm39) |
Y512C |
probably damaging |
Het |
| Wdfy3 |
T |
A |
5: 102,067,312 (GRCm39) |
N1207Y |
probably damaging |
Het |
| Wdr17 |
C |
T |
8: 55,134,434 (GRCm39) |
G349R |
probably damaging |
Het |
| Wdr70 |
A |
G |
15: 7,951,586 (GRCm39) |
L417S |
possibly damaging |
Het |
| Wdr81 |
A |
C |
11: 75,341,722 (GRCm39) |
S1182A |
possibly damaging |
Het |
| Zfp458 |
A |
T |
13: 67,405,256 (GRCm39) |
C391* |
probably null |
Het |
| Zfp638 |
A |
G |
6: 83,953,396 (GRCm39) |
E1167G |
probably damaging |
Het |
| Zfp763 |
T |
A |
17: 33,238,569 (GRCm39) |
D192V |
probably benign |
Het |
| Zfp853 |
T |
G |
5: 143,274,624 (GRCm39) |
Q332P |
unknown |
Het |
|
| Other mutations in Arap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00481:Arap2
|
APN |
5 |
62,793,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00642:Arap2
|
APN |
5 |
62,890,401 (GRCm39) |
nonsense |
probably null |
|
|
IGL00705:Arap2
|
APN |
5 |
62,835,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00942:Arap2
|
APN |
5 |
62,855,732 (GRCm39) |
nonsense |
probably null |
|
|
IGL01069:Arap2
|
APN |
5 |
62,807,199 (GRCm39) |
missense |
probably benign |
|
|
IGL01601:Arap2
|
APN |
5 |
62,798,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01986:Arap2
|
APN |
5 |
62,779,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02032:Arap2
|
APN |
5 |
62,828,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02262:Arap2
|
APN |
5 |
62,800,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02331:Arap2
|
APN |
5 |
62,807,025 (GRCm39) |
splice site |
probably benign |
|
|
IGL02527:Arap2
|
APN |
5 |
62,906,650 (GRCm39) |
missense |
probably benign |
|
|
IGL02803:Arap2
|
APN |
5 |
62,906,452 (GRCm39) |
missense |
probably benign |
|
|
IGL02864:Arap2
|
APN |
5 |
62,835,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03078:Arap2
|
APN |
5 |
62,890,408 (GRCm39) |
splice site |
probably benign |
|
|
IGL03154:Arap2
|
APN |
5 |
62,800,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03213:Arap2
|
APN |
5 |
62,906,438 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Arap2
|
APN |
5 |
62,779,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03288:Arap2
|
APN |
5 |
62,761,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4354001:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0012:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0166:Arap2
|
UTSW |
5 |
62,833,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0472:Arap2
|
UTSW |
5 |
62,864,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0506:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0551:Arap2
|
UTSW |
5 |
62,798,666 (GRCm39) |
splice site |
probably null |
|
|
R0607:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0617:Arap2
|
UTSW |
5 |
62,807,250 (GRCm39) |
splice site |
probably benign |
|
|
R0975:Arap2
|
UTSW |
5 |
62,888,229 (GRCm39) |
splice site |
probably benign |
|
|
R0976:Arap2
|
UTSW |
5 |
62,807,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1164:Arap2
|
UTSW |
5 |
62,840,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1268:Arap2
|
UTSW |
5 |
62,887,964 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1480:Arap2
|
UTSW |
5 |
62,826,472 (GRCm39) |
nonsense |
probably null |
|
|
R1502:Arap2
|
UTSW |
5 |
62,761,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1543:Arap2
|
UTSW |
5 |
62,763,498 (GRCm39) |
nonsense |
probably null |
|
|
R1865:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1962:Arap2
|
UTSW |
5 |
62,834,007 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2040:Arap2
|
UTSW |
5 |
62,906,259 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2118:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Arap2
|
UTSW |
5 |
62,835,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2201:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2215:Arap2
|
UTSW |
5 |
62,834,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3027:Arap2
|
UTSW |
5 |
62,827,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3053:Arap2
|
UTSW |
5 |
62,906,200 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3975:Arap2
|
UTSW |
5 |
62,906,237 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4272:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4273:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4326:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4327:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4328:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4451:Arap2
|
UTSW |
5 |
62,906,513 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4659:Arap2
|
UTSW |
5 |
62,811,469 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4665:Arap2
|
UTSW |
5 |
62,827,312 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4715:Arap2
|
UTSW |
5 |
62,906,437 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4808:Arap2
|
UTSW |
5 |
62,887,984 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4941:Arap2
|
UTSW |
5 |
62,906,821 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4983:Arap2
|
UTSW |
5 |
62,833,868 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5095:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Arap2
|
UTSW |
5 |
62,826,524 (GRCm39) |
nonsense |
probably null |
|
|
R5201:Arap2
|
UTSW |
5 |
62,840,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Arap2
|
UTSW |
5 |
62,872,089 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5359:Arap2
|
UTSW |
5 |
62,840,762 (GRCm39) |
nonsense |
probably null |
|
|
R5503:Arap2
|
UTSW |
5 |
62,787,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Arap2
|
UTSW |
5 |
62,772,410 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5764:Arap2
|
UTSW |
5 |
62,800,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Arap2
|
UTSW |
5 |
62,834,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5846:Arap2
|
UTSW |
5 |
62,807,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6084:Arap2
|
UTSW |
5 |
62,828,297 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6173:Arap2
|
UTSW |
5 |
62,906,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Arap2
|
UTSW |
5 |
62,872,074 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6249:Arap2
|
UTSW |
5 |
62,803,536 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6386:Arap2
|
UTSW |
5 |
62,761,865 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6424:Arap2
|
UTSW |
5 |
62,840,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6744:Arap2
|
UTSW |
5 |
62,906,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6766:Arap2
|
UTSW |
5 |
62,834,443 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6990:Arap2
|
UTSW |
5 |
62,833,860 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7067:Arap2
|
UTSW |
5 |
62,811,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7098:Arap2
|
UTSW |
5 |
62,833,293 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7107:Arap2
|
UTSW |
5 |
62,763,551 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7156:Arap2
|
UTSW |
5 |
62,761,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Arap2
|
UTSW |
5 |
62,761,621 (GRCm39) |
missense |
probably benign |
|
|
R7187:Arap2
|
UTSW |
5 |
62,826,396 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7197:Arap2
|
UTSW |
5 |
62,798,729 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7214:Arap2
|
UTSW |
5 |
62,906,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7317:Arap2
|
UTSW |
5 |
62,807,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7392:Arap2
|
UTSW |
5 |
62,855,728 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7438:Arap2
|
UTSW |
5 |
62,906,818 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7452:Arap2
|
UTSW |
5 |
62,833,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7495:Arap2
|
UTSW |
5 |
62,833,893 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7796:Arap2
|
UTSW |
5 |
62,888,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7936:Arap2
|
UTSW |
5 |
62,888,048 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8116:Arap2
|
UTSW |
5 |
62,887,954 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8172:Arap2
|
UTSW |
5 |
62,779,324 (GRCm39) |
splice site |
probably null |
|
|
R8277:Arap2
|
UTSW |
5 |
62,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Arap2
|
UTSW |
5 |
62,761,669 (GRCm39) |
nonsense |
probably null |
|
|
R8398:Arap2
|
UTSW |
5 |
62,906,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Arap2
|
UTSW |
5 |
62,888,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Arap2
|
UTSW |
5 |
62,855,668 (GRCm39) |
nonsense |
probably null |
|
|
R9102:Arap2
|
UTSW |
5 |
62,906,341 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9121:Arap2
|
UTSW |
5 |
62,906,326 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9174:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9222:Arap2
|
UTSW |
5 |
62,828,421 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9281:Arap2
|
UTSW |
5 |
62,906,848 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9399:Arap2
|
UTSW |
5 |
62,763,455 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9450:Arap2
|
UTSW |
5 |
62,855,762 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9467:Arap2
|
UTSW |
5 |
62,887,900 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9567:Arap2
|
UTSW |
5 |
62,761,841 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9577:Arap2
|
UTSW |
5 |
62,769,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9626:Arap2
|
UTSW |
5 |
62,906,878 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9688:Arap2
|
UTSW |
5 |
62,872,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCCTGTAAATAGTATGCTGTCCAAC -3'
(R):5'- GGCTGCTCCTTTGAACAGTAG -3'
Sequencing Primer
(F):5'- GGTGAAAATATTTAAAGGCTGCTGC -3'
(R):5'- TCGAAGAACTTCAAACCGTGTGTG -3'
|
| Posted On |
2016-09-01 |
Incidental Mutation