Incidental Mutation 'R5426:Gemin5'
| ID |
426903 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Gemin5
|
| Ensembl Gene |
ENSMUSG00000037275 |
| Gene Name |
gem nuclear organelle associated protein 5 |
| Synonyms |
|
| MMRRC Submission |
042992-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R5426 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
58010828-58059365 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 58016113 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 1297
(S1297P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000099772
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035604]
[ENSMUST00000102711]
[ENSMUST00000172035]
|
| AlphaFold |
Q8BX17 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000035604
AA Change: S1298P
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| SMART Domains |
Protein: ENSMUSP00000036603
Gene: ENSMUSG00000037275
AA Change: S1298P
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
53 |
95 |
1.47e-6 |
SMART |
|
WD40
|
98 |
138 |
6.19e-1 |
SMART |
|
WD40
|
141 |
180 |
1.54e0 |
SMART |
|
WD40
|
184 |
255 |
2.45e-8 |
SMART |
|
WD40
|
280 |
312 |
1.42e2 |
SMART |
|
WD40
|
316 |
365 |
1.99e0 |
SMART |
|
WD40
|
368 |
408 |
5.15e-2 |
SMART |
|
WD40
|
415 |
455 |
8.49e-3 |
SMART |
|
WD40
|
460 |
511 |
8.84e1 |
SMART |
|
WD40
|
529 |
564 |
4.28e0 |
SMART |
|
WD40
|
567 |
613 |
2.24e-2 |
SMART |
|
WD40
|
628 |
668 |
2.2e-10 |
SMART |
|
WD40
|
671 |
711 |
2.31e-4 |
SMART |
|
low complexity region
|
731 |
754 |
N/A |
INTRINSIC |
|
low complexity region
|
788 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
813 |
844 |
N/A |
INTRINSIC |
|
low complexity region
|
1064 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1117 |
1132 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102711
AA Change: S1297P
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| SMART Domains |
Protein: ENSMUSP00000099772
Gene: ENSMUSG00000037275
AA Change: S1297P
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
53 |
95 |
1.47e-6 |
SMART |
|
WD40
|
98 |
138 |
6.19e-1 |
SMART |
|
WD40
|
141 |
180 |
1.54e0 |
SMART |
|
WD40
|
184 |
255 |
2.45e-8 |
SMART |
|
WD40
|
280 |
312 |
1.42e2 |
SMART |
|
WD40
|
316 |
365 |
1.99e0 |
SMART |
|
WD40
|
368 |
408 |
5.15e-2 |
SMART |
|
WD40
|
415 |
455 |
8.49e-3 |
SMART |
|
WD40
|
460 |
511 |
8.84e1 |
SMART |
|
WD40
|
529 |
564 |
4.28e0 |
SMART |
|
WD40
|
567 |
613 |
2.24e-2 |
SMART |
|
WD40
|
628 |
668 |
2.2e-10 |
SMART |
|
WD40
|
671 |
711 |
2.31e-4 |
SMART |
|
low complexity region
|
731 |
754 |
N/A |
INTRINSIC |
|
low complexity region
|
788 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
813 |
844 |
N/A |
INTRINSIC |
|
low complexity region
|
1063 |
1083 |
N/A |
INTRINSIC |
|
low complexity region
|
1116 |
1131 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129126
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172035
AA Change: S1298P
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000131842
Gene: ENSMUSG00000037275
AA Change: S1298P
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
53 |
95 |
1.47e-6 |
SMART |
|
WD40
|
98 |
138 |
6.19e-1 |
SMART |
|
WD40
|
141 |
180 |
1.54e0 |
SMART |
|
WD40
|
184 |
255 |
2.45e-8 |
SMART |
|
WD40
|
280 |
312 |
1.42e2 |
SMART |
|
WD40
|
316 |
365 |
1.99e0 |
SMART |
|
WD40
|
368 |
408 |
5.15e-2 |
SMART |
|
WD40
|
415 |
455 |
8.49e-3 |
SMART |
|
WD40
|
460 |
511 |
8.84e1 |
SMART |
|
WD40
|
529 |
564 |
4.28e0 |
SMART |
|
WD40
|
567 |
613 |
2.24e-2 |
SMART |
|
WD40
|
628 |
668 |
2.2e-10 |
SMART |
|
WD40
|
671 |
711 |
2.31e-4 |
SMART |
|
low complexity region
|
731 |
754 |
N/A |
INTRINSIC |
|
low complexity region
|
788 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
813 |
844 |
N/A |
INTRINSIC |
|
low complexity region
|
1064 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1117 |
1132 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1000 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
97% (85/88) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2010315B03Rik |
T |
A |
9: 124,056,633 (GRCm39) |
H122L |
probably damaging |
Het |
| 9330182O14Rik |
G |
A |
15: 40,011,932 (GRCm39) |
M90I |
unknown |
Het |
| 9330182O14Rik |
G |
A |
15: 40,011,933 (GRCm39) |
D91N |
unknown |
Het |
| Abca13 |
T |
A |
11: 9,240,722 (GRCm39) |
S862T |
probably damaging |
Het |
| Acyp2 |
C |
T |
11: 30,456,354 (GRCm39) |
E98K |
possibly damaging |
Het |
| Adgb |
C |
A |
10: 10,226,004 (GRCm39) |
A1405S |
probably benign |
Het |
| Adpgk |
T |
A |
9: 59,204,832 (GRCm39) |
V86E |
probably damaging |
Het |
| Agfg2 |
G |
C |
5: 137,666,020 (GRCm39) |
P80A |
probably damaging |
Het |
| Akap11 |
G |
A |
14: 78,736,304 (GRCm39) |
Q1829* |
probably null |
Het |
| Aldh1l1 |
G |
A |
6: 90,536,281 (GRCm39) |
R62Q |
probably benign |
Het |
| Amd1 |
G |
T |
10: 40,166,183 (GRCm39) |
D265E |
probably damaging |
Het |
| Aox4 |
A |
T |
1: 58,259,253 (GRCm39) |
Q106L |
probably damaging |
Het |
| Arap2 |
A |
T |
5: 62,800,159 (GRCm39) |
N1289K |
probably benign |
Het |
| Arhgef12 |
T |
C |
9: 42,897,880 (GRCm39) |
S874G |
probably damaging |
Het |
| Ccdc166 |
T |
C |
15: 75,853,945 (GRCm39) |
Q45R |
possibly damaging |
Het |
| Cdc45 |
C |
T |
16: 18,614,647 (GRCm39) |
R205H |
probably damaging |
Het |
| Cdk14 |
A |
G |
5: 4,938,975 (GRCm39) |
S388P |
possibly damaging |
Het |
| Chgb |
A |
T |
2: 132,635,453 (GRCm39) |
Q465L |
possibly damaging |
Het |
| Commd9 |
T |
A |
2: 101,729,220 (GRCm39) |
W109R |
probably damaging |
Het |
| Cspg4b |
G |
A |
13: 113,505,587 (GRCm39) |
V2239I |
probably benign |
Het |
| Cyp2b9 |
T |
C |
7: 25,887,080 (GRCm39) |
V163A |
probably benign |
Het |
| Dcpp2 |
T |
A |
17: 24,118,287 (GRCm39) |
H27Q |
possibly damaging |
Het |
| Ddn |
T |
A |
15: 98,704,347 (GRCm39) |
E315V |
possibly damaging |
Het |
| Defb29 |
C |
A |
2: 152,380,868 (GRCm39) |
C47F |
probably damaging |
Het |
| Dnah7b |
T |
C |
1: 46,281,366 (GRCm39) |
M2809T |
possibly damaging |
Het |
| Dock4 |
A |
T |
12: 40,795,744 (GRCm39) |
I854F |
probably damaging |
Het |
| Dsg4 |
T |
C |
18: 20,591,541 (GRCm39) |
Y427H |
probably damaging |
Het |
| E130114P18Rik |
C |
T |
4: 97,578,907 (GRCm39) |
A23T |
unknown |
Het |
| Flacc1 |
T |
A |
1: 58,706,045 (GRCm39) |
K275* |
probably null |
Het |
| Gm10309 |
A |
C |
17: 86,806,161 (GRCm39) |
|
probably benign |
Het |
| Gpatch11 |
T |
A |
17: 79,148,663 (GRCm39) |
S155R |
possibly damaging |
Het |
| Grin2b |
C |
A |
6: 135,709,366 (GRCm39) |
Q1393H |
probably damaging |
Het |
| Heatr5b |
C |
T |
17: 79,081,142 (GRCm39) |
C1370Y |
probably damaging |
Het |
| Hmcn2 |
C |
T |
2: 31,226,556 (GRCm39) |
T177I |
possibly damaging |
Het |
| Ildr1 |
A |
T |
16: 36,529,981 (GRCm39) |
I123F |
probably damaging |
Het |
| Kalrn |
A |
T |
16: 34,083,023 (GRCm39) |
V644D |
probably damaging |
Het |
| Kifap3 |
A |
G |
1: 163,607,440 (GRCm39) |
M1V |
probably null |
Het |
| Klhl11 |
A |
G |
11: 100,354,942 (GRCm39) |
L293P |
probably damaging |
Het |
| Klrc3 |
G |
A |
6: 129,618,513 (GRCm39) |
S98L |
probably benign |
Het |
| Lrrc37 |
A |
T |
11: 103,511,586 (GRCm39) |
H127Q |
unknown |
Het |
| Med12l |
G |
A |
3: 59,156,143 (GRCm39) |
M1220I |
probably damaging |
Het |
| Ms4a7 |
C |
T |
19: 11,303,166 (GRCm39) |
|
probably null |
Het |
| Mybpc2 |
A |
G |
7: 44,159,253 (GRCm39) |
V599A |
probably benign |
Het |
| Naalad2 |
T |
C |
9: 18,258,815 (GRCm39) |
N487D |
probably benign |
Het |
| Nat8f7 |
T |
G |
6: 85,684,805 (GRCm39) |
S12R |
probably benign |
Het |
| Nefm |
T |
A |
14: 68,357,515 (GRCm39) |
|
probably benign |
Het |
| Nlrp5 |
T |
C |
7: 23,117,626 (GRCm39) |
V450A |
probably damaging |
Het |
| Nps |
G |
A |
7: 134,870,376 (GRCm39) |
|
probably null |
Het |
| Or13c7d |
A |
G |
4: 43,770,168 (GRCm39) |
I281T |
probably benign |
Het |
| Or2ag16 |
C |
A |
7: 106,351,773 (GRCm39) |
S274I |
probably benign |
Het |
| Or4a74 |
T |
C |
2: 89,440,083 (GRCm39) |
Y121C |
probably damaging |
Het |
| Or4b13 |
T |
A |
2: 90,082,955 (GRCm39) |
K126* |
probably null |
Het |
| Or5e1 |
T |
C |
7: 108,354,924 (GRCm39) |
L287P |
possibly damaging |
Het |
| Or5h24 |
G |
T |
16: 58,918,665 (GRCm39) |
P230Q |
possibly damaging |
Het |
| Or5p67 |
T |
C |
7: 107,922,017 (GRCm39) |
N289D |
probably damaging |
Het |
| Oxct2a |
C |
A |
4: 123,216,506 (GRCm39) |
G292W |
possibly damaging |
Het |
| Pramel32 |
T |
A |
4: 88,547,647 (GRCm39) |
|
probably benign |
Het |
| Prr27 |
T |
C |
5: 87,998,744 (GRCm39) |
|
probably benign |
Het |
| Ptx3 |
T |
C |
3: 66,128,143 (GRCm39) |
M68T |
probably damaging |
Het |
| Rufy1 |
A |
G |
11: 50,312,561 (GRCm39) |
L131S |
probably damaging |
Het |
| Septin7 |
T |
A |
9: 25,197,986 (GRCm39) |
I100N |
possibly damaging |
Het |
| Sgms2 |
T |
C |
3: 131,135,446 (GRCm39) |
I143V |
probably benign |
Het |
| Slc25a34 |
A |
G |
4: 141,350,877 (GRCm39) |
V44A |
probably damaging |
Het |
| Slc28a3 |
T |
A |
13: 58,710,968 (GRCm39) |
D518V |
probably damaging |
Het |
| Slc6a7 |
C |
T |
18: 61,136,308 (GRCm39) |
|
probably null |
Het |
| Slco4a1 |
C |
A |
2: 180,113,028 (GRCm39) |
A420D |
possibly damaging |
Het |
| Smap1 |
T |
C |
1: 23,888,471 (GRCm39) |
T180A |
probably benign |
Het |
| Specc1l |
T |
C |
10: 75,103,384 (GRCm39) |
S920P |
probably benign |
Het |
| Tgtp2 |
A |
G |
11: 48,950,083 (GRCm39) |
M163T |
probably benign |
Het |
| Tiam1 |
G |
T |
16: 89,662,280 (GRCm39) |
Q613K |
possibly damaging |
Het |
| Vsig10l |
T |
A |
7: 43,114,247 (GRCm39) |
S190T |
probably damaging |
Het |
| Vwa3b |
A |
G |
1: 37,154,752 (GRCm39) |
Y512C |
probably damaging |
Het |
| Wdfy3 |
T |
A |
5: 102,067,312 (GRCm39) |
N1207Y |
probably damaging |
Het |
| Wdr17 |
C |
T |
8: 55,134,434 (GRCm39) |
G349R |
probably damaging |
Het |
| Wdr70 |
A |
G |
15: 7,951,586 (GRCm39) |
L417S |
possibly damaging |
Het |
| Wdr81 |
A |
C |
11: 75,341,722 (GRCm39) |
S1182A |
possibly damaging |
Het |
| Zfp458 |
A |
T |
13: 67,405,256 (GRCm39) |
C391* |
probably null |
Het |
| Zfp638 |
A |
G |
6: 83,953,396 (GRCm39) |
E1167G |
probably damaging |
Het |
| Zfp763 |
T |
A |
17: 33,238,569 (GRCm39) |
D192V |
probably benign |
Het |
| Zfp853 |
T |
G |
5: 143,274,624 (GRCm39) |
Q332P |
unknown |
Het |
|
| Other mutations in Gemin5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00423:Gemin5
|
APN |
11 |
58,054,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00540:Gemin5
|
APN |
11 |
58,051,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01521:Gemin5
|
APN |
11 |
58,025,744 (GRCm39) |
splice site |
probably benign |
|
|
IGL02190:Gemin5
|
APN |
11 |
58,025,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02274:Gemin5
|
APN |
11 |
58,047,621 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02494:Gemin5
|
APN |
11 |
58,012,583 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL02549:Gemin5
|
APN |
11 |
58,025,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02740:Gemin5
|
APN |
11 |
58,042,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02815:Gemin5
|
APN |
11 |
58,037,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02823:Gemin5
|
APN |
11 |
58,058,531 (GRCm39) |
splice site |
probably benign |
|
|
IGL02939:Gemin5
|
APN |
11 |
58,047,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Landscape
|
UTSW |
11 |
58,054,730 (GRCm39) |
missense |
probably benign |
0.16 |
|
R0101:Gemin5
|
UTSW |
11 |
58,036,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0479:Gemin5
|
UTSW |
11 |
58,030,377 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1481:Gemin5
|
UTSW |
11 |
58,032,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1642:Gemin5
|
UTSW |
11 |
58,029,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1648:Gemin5
|
UTSW |
11 |
58,038,805 (GRCm39) |
nonsense |
probably null |
|
|
R1980:Gemin5
|
UTSW |
11 |
58,027,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3079:Gemin5
|
UTSW |
11 |
58,036,345 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3418:Gemin5
|
UTSW |
11 |
58,047,454 (GRCm39) |
splice site |
probably null |
|
|
R4260:Gemin5
|
UTSW |
11 |
58,059,185 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4396:Gemin5
|
UTSW |
11 |
58,030,375 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4902:Gemin5
|
UTSW |
11 |
58,055,103 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5178:Gemin5
|
UTSW |
11 |
58,037,344 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5296:Gemin5
|
UTSW |
11 |
58,020,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5350:Gemin5
|
UTSW |
11 |
58,032,412 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5494:Gemin5
|
UTSW |
11 |
58,021,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5744:Gemin5
|
UTSW |
11 |
58,046,009 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5889:Gemin5
|
UTSW |
11 |
58,013,181 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5984:Gemin5
|
UTSW |
11 |
58,047,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6844:Gemin5
|
UTSW |
11 |
58,054,730 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6934:Gemin5
|
UTSW |
11 |
58,038,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6999:Gemin5
|
UTSW |
11 |
58,015,947 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7015:Gemin5
|
UTSW |
11 |
58,047,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7144:Gemin5
|
UTSW |
11 |
58,032,489 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7176:Gemin5
|
UTSW |
11 |
58,056,828 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7540:Gemin5
|
UTSW |
11 |
58,021,228 (GRCm39) |
splice site |
probably null |
|
|
R7670:Gemin5
|
UTSW |
11 |
58,038,754 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7717:Gemin5
|
UTSW |
11 |
58,042,356 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7791:Gemin5
|
UTSW |
11 |
58,015,819 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7981:Gemin5
|
UTSW |
11 |
58,036,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8050:Gemin5
|
UTSW |
11 |
58,019,686 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8307:Gemin5
|
UTSW |
11 |
58,042,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8353:Gemin5
|
UTSW |
11 |
58,016,065 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8371:Gemin5
|
UTSW |
11 |
58,017,384 (GRCm39) |
missense |
probably benign |
|
|
R8453:Gemin5
|
UTSW |
11 |
58,016,065 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9181:Gemin5
|
UTSW |
11 |
58,021,035 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9294:Gemin5
|
UTSW |
11 |
58,028,574 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9400:Gemin5
|
UTSW |
11 |
58,028,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9672:Gemin5
|
UTSW |
11 |
58,058,585 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9722:Gemin5
|
UTSW |
11 |
58,041,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9790:Gemin5
|
UTSW |
11 |
58,020,846 (GRCm39) |
nonsense |
probably null |
|
|
R9791:Gemin5
|
UTSW |
11 |
58,020,846 (GRCm39) |
nonsense |
probably null |
|
|
X0066:Gemin5
|
UTSW |
11 |
58,042,361 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1186:Gemin5
|
UTSW |
11 |
58,016,044 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1186:Gemin5
|
UTSW |
11 |
58,013,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1186:Gemin5
|
UTSW |
11 |
58,037,345 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1186:Gemin5
|
UTSW |
11 |
58,030,401 (GRCm39) |
missense |
probably benign |
|
|
Z1186:Gemin5
|
UTSW |
11 |
58,030,336 (GRCm39) |
missense |
probably benign |
|
|
Z1186:Gemin5
|
UTSW |
11 |
58,020,897 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Gemin5
|
UTSW |
11 |
58,013,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1187:Gemin5
|
UTSW |
11 |
58,037,345 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1187:Gemin5
|
UTSW |
11 |
58,030,401 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Gemin5
|
UTSW |
11 |
58,030,336 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Gemin5
|
UTSW |
11 |
58,020,897 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Gemin5
|
UTSW |
11 |
58,016,044 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1188:Gemin5
|
UTSW |
11 |
58,020,897 (GRCm39) |
missense |
probably benign |
|
|
Z1188:Gemin5
|
UTSW |
11 |
58,030,336 (GRCm39) |
missense |
probably benign |
|
|
Z1188:Gemin5
|
UTSW |
11 |
58,030,401 (GRCm39) |
missense |
probably benign |
|
|
Z1188:Gemin5
|
UTSW |
11 |
58,037,345 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1188:Gemin5
|
UTSW |
11 |
58,013,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1188:Gemin5
|
UTSW |
11 |
58,016,044 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1189:Gemin5
|
UTSW |
11 |
58,016,044 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1189:Gemin5
|
UTSW |
11 |
58,013,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1189:Gemin5
|
UTSW |
11 |
58,037,345 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1189:Gemin5
|
UTSW |
11 |
58,030,401 (GRCm39) |
missense |
probably benign |
|
|
Z1189:Gemin5
|
UTSW |
11 |
58,030,336 (GRCm39) |
missense |
probably benign |
|
|
Z1189:Gemin5
|
UTSW |
11 |
58,020,897 (GRCm39) |
missense |
probably benign |
|
|
Z1190:Gemin5
|
UTSW |
11 |
58,016,044 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1190:Gemin5
|
UTSW |
11 |
58,013,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1190:Gemin5
|
UTSW |
11 |
58,037,345 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1190:Gemin5
|
UTSW |
11 |
58,030,401 (GRCm39) |
missense |
probably benign |
|
|
Z1190:Gemin5
|
UTSW |
11 |
58,030,336 (GRCm39) |
missense |
probably benign |
|
|
Z1190:Gemin5
|
UTSW |
11 |
58,020,897 (GRCm39) |
missense |
probably benign |
|
|
Z1191:Gemin5
|
UTSW |
11 |
58,016,044 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1191:Gemin5
|
UTSW |
11 |
58,013,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1191:Gemin5
|
UTSW |
11 |
58,037,345 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1191:Gemin5
|
UTSW |
11 |
58,030,401 (GRCm39) |
missense |
probably benign |
|
|
Z1191:Gemin5
|
UTSW |
11 |
58,030,336 (GRCm39) |
missense |
probably benign |
|
|
Z1191:Gemin5
|
UTSW |
11 |
58,020,897 (GRCm39) |
missense |
probably benign |
|
|
Z1192:Gemin5
|
UTSW |
11 |
58,016,044 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1192:Gemin5
|
UTSW |
11 |
58,013,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1192:Gemin5
|
UTSW |
11 |
58,037,345 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1192:Gemin5
|
UTSW |
11 |
58,030,401 (GRCm39) |
missense |
probably benign |
|
|
Z1192:Gemin5
|
UTSW |
11 |
58,030,336 (GRCm39) |
missense |
probably benign |
|
|
Z1192:Gemin5
|
UTSW |
11 |
58,020,897 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGTGTCTCTTGGACTTCGGC -3'
(R):5'- AGACAGGCTTCTCACAGATAAAG -3'
Sequencing Primer
(F):5'- TGGACTTCGGCTACAGTCC -3'
(R):5'- GGCTTCTCACAGATAAAGAAATGC -3'
|
| Posted On |
2016-09-01 |
Incidental Mutation