Mutagenetix > Incidental Mutation

Incidental Mutation 'R5372:Tacc2'

428796

Institutional Source

Beutler Lab

Gene Symbol

Tacc2

Ensembl Gene

ENSMUSG00000030852

Gene Name

transforming, acidic coiled-coil containing protein 2

Synonyms

MMRRC Submission

042948-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5372 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

130179168-130366515 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 130224990 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Glutamine at position 558 (H558Q)

Ref Sequence

ENSEMBL: ENSMUSP00000146419 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000059145] [ENSMUST00000084513] [ENSMUST00000124096] [ENSMUST00000207789] [ENSMUST00000207918] [ENSMUST00000208722] [ENSMUST00000215492]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000059145

SMART Domains

Protein: ENSMUSP00000061242
Gene: ENSMUSG00000030852

Domain	Start	End	E-Value	Type
low complexity region	87	102	N/A	INTRINSIC
low complexity region	147	173	N/A	INTRINSIC
internal_repeat_1	181	291	2.03e-5	PROSPERO
low complexity region	345	356	N/A	INTRINSIC
internal_repeat_1	483	566	2.03e-5	PROSPERO
low complexity region	571	586	N/A	INTRINSIC
low complexity region	603	614	N/A	INTRINSIC
low complexity region	648	662	N/A	INTRINSIC
coiled coil region	873	900	N/A	INTRINSIC
Pfam:TACC	939	1145	4e-85	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000084513
AA Change: H558Q

PolyPhen 2 Score 0.051 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000081561
Gene: ENSMUSG00000030852
AA Change: H558Q

Domain	Start	End	E-Value	Type
internal_repeat_1	19	346	3.83e-6	PROSPERO
low complexity region	398	410	N/A	INTRINSIC
low complexity region	413	431	N/A	INTRINSIC
internal_repeat_1	778	1068	3.83e-6	PROSPERO
low complexity region	1397	1415	N/A	INTRINSIC
low complexity region	1723	1739	N/A	INTRINSIC
low complexity region	1794	1809	N/A	INTRINSIC
low complexity region	1854	1880	N/A	INTRINSIC
low complexity region	2052	2063	N/A	INTRINSIC
low complexity region	2278	2293	N/A	INTRINSIC
low complexity region	2310	2321	N/A	INTRINSIC
low complexity region	2355	2369	N/A	INTRINSIC
coiled coil region	2606	2633	N/A	INTRINSIC
Pfam:TACC	2673	2873	6.1e-87	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000124096

SMART Domains

Protein: ENSMUSP00000130971
Gene: ENSMUSG00000030849

Domain	Start	End	E-Value	Type
Pfam:Pkinase	1	118	4.8e-19	PFAM
Pfam:Pkinase_Tyr	1	118	1.7e-50	PFAM
low complexity region	146	160	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000207789

Predicted Effect

probably benign
Transcript: ENSMUST00000207918
AA Change: H558Q

PolyPhen 2 Score 0.094 (Sensitivity: 0.93; Specificity: 0.85)

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000207999

Predicted Effect

probably benign
Transcript: ENSMUST00000208722

Predicted Effect

probably benign
Transcript: ENSMUST00000215492
AA Change: H577Q

PolyPhen 2 Score 0.057 (Sensitivity: 0.94; Specificity: 0.84)

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 97.2%
20x: 95.2%

Validation Efficiency

96% (89/93)

MGI Phenotype

FUNCTION: This gene encodes a member of the transforming, acidic coiled-coil (TACC) family of proteins. Members of this family are centrosomal proteins that interact with microtubules and tubulin. TACC proteins are thought to be involved in centrosome/mitotic spindle dynamics and gene regulation. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous null mice are healthy and fertile and do not display any increase in tumorigenesis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 79 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca4	T	A	3: 121,848,988 (GRCm39)	D108E	probably damaging	Het
Abhd12b	A	G	12: 70,227,800 (GRCm39)	D194G	probably damaging	Het
Adck5	A	G	15: 76,478,707 (GRCm39)		probably benign	Het
Adgrb3	C	T	1: 25,167,940 (GRCm39)	V792I	probably benign	Het
Anxa8	G	A	14: 33,815,868 (GRCm39)	V174M	probably damaging	Het
Apol9b	A	T	15: 77,619,920 (GRCm39)	R239W	probably benign	Het
Arhgap26	A	G	18: 38,775,509 (GRCm39)		noncoding transcript	Het
Atrnl1	A	G	19: 57,743,968 (GRCm39)	Y1190C	probably benign	Het
Brinp3	T	G	1: 146,707,464 (GRCm39)	L376R	probably damaging	Het
Btbd2	A	T	10: 80,484,475 (GRCm39)	M132K	probably damaging	Het
C130073F10Rik	A	T	4: 101,747,684 (GRCm39)	I115K	probably damaging	Het
C1ra	T	A	6: 124,498,584 (GRCm39)	Y426N	probably damaging	Het
Cacna1b	A	T	2: 24,623,971 (GRCm39)	V203E	probably damaging	Het
Catsperg1	T	A	7: 28,910,137 (GRCm39)	D68V	probably benign	Het
Ccdc158	A	C	5: 92,780,419 (GRCm39)	S885A	possibly damaging	Het
Cdc42bpa	T	C	1: 179,892,544 (GRCm39)	V236A	probably damaging	Het
Cdca7	A	T	2: 72,312,793 (GRCm39)	E176D	probably damaging	Het
Cdk17	A	G	10: 93,061,901 (GRCm39)	D211G	probably benign	Het
Clca3a2	A	C	3: 144,503,286 (GRCm39)	M888R	probably benign	Het
Clcn7	T	A	17: 25,376,153 (GRCm39)	M568K	possibly damaging	Het
Clip1	G	T	5: 123,768,303 (GRCm39)	N811K	probably benign	Het
Col12a1	T	A	9: 79,585,648 (GRCm39)	Y1243F	probably damaging	Het
Dctn1	T	A	6: 83,167,192 (GRCm39)	D315E	probably damaging	Het
Dgcr2	T	C	16: 17,690,508 (GRCm39)	T41A	probably benign	Het
Dync2h1	G	A	9: 7,176,962 (GRCm39)		probably benign	Het
Ep300	A	G	15: 81,521,031 (GRCm39)	I1264V	unknown	Het
Fam167b	A	T	4: 129,472,092 (GRCm39)	L26Q	possibly damaging	Het
Fam178b	T	A	1: 36,603,929 (GRCm39)	I457F	possibly damaging	Het
Fgd4	A	T	16: 16,302,155 (GRCm39)	N133K	probably benign	Het
Fndc1	C	G	17: 7,984,042 (GRCm39)	V1295L	unknown	Het
Gad2	A	T	2: 22,580,255 (GRCm39)	D552V	possibly damaging	Het
Hars2	T	C	18: 36,923,534 (GRCm39)	Y361H	possibly damaging	Het
Heca	T	A	10: 17,790,887 (GRCm39)	S390C	probably damaging	Het
Hephl1	G	T	9: 15,009,195 (GRCm39)	Y132*	probably null	Het
Hormad1	T	A	3: 95,483,735 (GRCm39)	D182E	probably damaging	Het
Ifna15	G	A	4: 88,476,338 (GRCm39)	P49S	probably damaging	Het
Khsrp	T	C	17: 57,331,292 (GRCm39)	T429A	possibly damaging	Het
Magi2	A	G	5: 20,907,108 (GRCm39)	Q1094R	possibly damaging	Het
Map3k11	T	A	19: 5,740,990 (GRCm39)	I239K	probably damaging	Het
Mtus2	A	G	5: 148,250,222 (GRCm39)	T1319A	probably damaging	Het
Nup54	A	G	5: 92,565,716 (GRCm39)	I406T	probably damaging	Het
Nxpe2	T	C	9: 48,250,819 (GRCm39)	T43A	possibly damaging	Het
Nynrin	A	G	14: 56,105,948 (GRCm39)	E889G	probably benign	Het
Opa1	A	C	16: 29,404,937 (GRCm39)	H45P	probably benign	Het
Or14c44	T	A	7: 86,062,176 (GRCm39)	I202N	possibly damaging	Het
Or4f60	A	G	2: 111,902,454 (GRCm39)	I158T	probably benign	Het
Or56b2j	A	G	7: 104,353,002 (GRCm39)	D76G	probably benign	Het
Or8a1b	T	C	9: 37,623,234 (GRCm39)	M114V	possibly damaging	Het
Otx1	C	A	11: 21,947,037 (GRCm39)	A91S	probably damaging	Het
Papola	A	G	12: 105,793,309 (GRCm39)	K543R	probably benign	Het
Plcxd3	G	A	15: 4,604,270 (GRCm39)	V293I	probably benign	Het
Polr2g	T	C	19: 8,774,667 (GRCm39)	Y72C	probably damaging	Het
Ppp1r21	A	G	17: 88,858,103 (GRCm39)	K205E	probably benign	Het
Ptpre	A	G	7: 135,255,669 (GRCm39)	K53E	possibly damaging	Het
Rasal3	T	C	17: 32,610,318 (GRCm39)	K990E	probably benign	Het
Rgs3	A	T	4: 62,570,934 (GRCm39)		probably benign	Het
Rhd	A	G	4: 134,611,943 (GRCm39)	T254A	possibly damaging	Het
Rufy4	T	C	1: 74,186,822 (GRCm39)	C537R	probably damaging	Het
Scube3	G	T	17: 28,371,456 (GRCm39)	C57F	probably damaging	Het
Sh2d5	A	G	4: 137,982,010 (GRCm39)	D57G	possibly damaging	Het
Slc12a6	T	A	2: 112,177,705 (GRCm39)	L608*	probably null	Het
Slk	A	T	19: 47,613,832 (GRCm39)	N896I	probably damaging	Het
Smc6	A	G	12: 11,332,431 (GRCm39)	D211G	probably damaging	Het
Sox6	A	T	7: 115,149,386 (GRCm39)	Y371*	probably null	Het
Srcap	G	A	7: 127,156,785 (GRCm39)		probably null	Het
Stard5	T	A	7: 83,282,428 (GRCm39)	D80E	probably damaging	Het
Supv3l1	C	T	10: 62,268,136 (GRCm39)	V570M	probably damaging	Het
Syt7	G	T	19: 10,403,985 (GRCm39)	V180L	probably damaging	Het
Tas2r120	T	A	6: 132,634,446 (GRCm39)	M176K	possibly damaging	Het
Tmem135	A	T	7: 88,814,382 (GRCm39)		probably null	Het
Trim35	T	C	14: 66,534,715 (GRCm39)	V66A	possibly damaging	Het
Tspan12	A	G	6: 21,772,698 (GRCm39)	S284P	probably benign	Het
Ttll3	A	T	6: 113,378,382 (GRCm39)	K257*	probably null	Het
Uggt1	C	A	1: 36,283,141 (GRCm39)		probably benign	Het
Vmn2r7	T	A	3: 64,623,745 (GRCm39)	I283F	probably damaging	Het
Wdfy2	T	G	14: 63,192,334 (GRCm39)	H363Q	probably damaging	Het
Wdr4	T	A	17: 31,729,554 (GRCm39)	K95N	probably damaging	Het
Zfp141	T	C	7: 42,126,620 (GRCm39)	N91S	possibly damaging	Het
Zfp383	C	T	7: 29,614,695 (GRCm39)	R317*	probably null	Het

Other mutations in Tacc2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00836:Tacc2	APN	7	130,360,898 (GRCm39)	missense	probably damaging	1.00
IGL01396:Tacc2	APN	7	130,360,919 (GRCm39)	missense	probably damaging	0.98
IGL01621:Tacc2	APN	7	130,331,498 (GRCm39)	missense	probably damaging	0.99
IGL02000:Tacc2	APN	7	130,330,898 (GRCm39)	splice site	probably null
IGL02075:Tacc2	APN	7	130,330,582 (GRCm39)	missense	probably benign	0.03
IGL02201:Tacc2	APN	7	130,227,942 (GRCm39)	missense	possibly damaging	0.84
IGL02205:Tacc2	APN	7	130,228,412 (GRCm39)	missense	probably damaging	1.00
IGL02399:Tacc2	APN	7	130,225,129 (GRCm39)	missense	probably benign	0.15
IGL02456:Tacc2	APN	7	130,227,991 (GRCm39)	missense	probably benign	0.35
IGL02559:Tacc2	APN	7	130,360,997 (GRCm39)	missense	probably damaging	1.00
IGL02734:Tacc2	APN	7	130,227,829 (GRCm39)	missense	probably damaging	0.98
IGL02800:Tacc2	APN	7	130,225,809 (GRCm39)	missense	probably benign	0.40
IGL02938:Tacc2	APN	7	130,330,671 (GRCm39)	missense	probably damaging	1.00
IGL03031:Tacc2	APN	7	130,225,585 (GRCm39)	missense	possibly damaging	0.94
IGL03278:Tacc2	APN	7	130,335,298 (GRCm39)	critical splice donor site	probably null
IGL03283:Tacc2	APN	7	130,343,996 (GRCm39)	missense	possibly damaging	0.47
IGL03371:Tacc2	APN	7	130,227,791 (GRCm39)	missense	possibly damaging	0.90
aces	UTSW	7	130,335,258 (GRCm39)	missense	probably damaging	1.00
Jacks	UTSW	7	130,227,494 (GRCm39)	missense	probably damaging	0.98
kings	UTSW	7	130,225,213 (GRCm39)	missense	probably damaging	0.96
R0002:Tacc2	UTSW	7	130,223,515 (GRCm39)	missense	probably damaging	0.99
R0119:Tacc2	UTSW	7	130,223,605 (GRCm39)	missense	probably damaging	0.98
R0244:Tacc2	UTSW	7	130,353,555 (GRCm39)	splice site	probably benign
R0619:Tacc2	UTSW	7	130,318,483 (GRCm39)	missense	probably damaging	1.00
R0624:Tacc2	UTSW	7	130,179,239 (GRCm39)	missense	probably damaging	0.99
R0632:Tacc2	UTSW	7	130,227,325 (GRCm39)	nonsense	probably null
R1015:Tacc2	UTSW	7	130,225,795 (GRCm39)	missense	probably benign
R1081:Tacc2	UTSW	7	130,330,304 (GRCm39)	missense	possibly damaging	0.46
R1086:Tacc2	UTSW	7	130,228,227 (GRCm39)	missense	possibly damaging	0.94
R1351:Tacc2	UTSW	7	130,264,733 (GRCm39)	intron	probably benign
R1538:Tacc2	UTSW	7	130,227,149 (GRCm39)	missense	probably benign	0.03
R1743:Tacc2	UTSW	7	130,228,328 (GRCm39)	nonsense	probably null
R1771:Tacc2	UTSW	7	130,343,970 (GRCm39)	missense	probably damaging	1.00
R1876:Tacc2	UTSW	7	130,225,475 (GRCm39)	missense	probably benign	0.38
R1893:Tacc2	UTSW	7	130,227,055 (GRCm39)	missense	probably benign	0.01
R1899:Tacc2	UTSW	7	130,225,932 (GRCm39)	missense	possibly damaging	0.81
R2005:Tacc2	UTSW	7	130,333,280 (GRCm39)	missense	probably damaging	1.00
R2131:Tacc2	UTSW	7	130,223,587 (GRCm39)	missense	possibly damaging	0.90
R2338:Tacc2	UTSW	7	130,335,299 (GRCm39)	splice site	probably null
R2407:Tacc2	UTSW	7	130,223,770 (GRCm39)	missense	possibly damaging	0.65
R3051:Tacc2	UTSW	7	130,227,226 (GRCm39)	missense	possibly damaging	0.81
R3052:Tacc2	UTSW	7	130,227,226 (GRCm39)	missense	possibly damaging	0.81
R3053:Tacc2	UTSW	7	130,227,226 (GRCm39)	missense	possibly damaging	0.81
R3116:Tacc2	UTSW	7	130,360,979 (GRCm39)	missense	probably damaging	1.00
R3412:Tacc2	UTSW	7	130,336,724 (GRCm39)	missense	probably benign	0.02
R3683:Tacc2	UTSW	7	130,226,800 (GRCm39)	missense	probably benign	0.40
R3685:Tacc2	UTSW	7	130,226,800 (GRCm39)	missense	probably benign	0.40
R3872:Tacc2	UTSW	7	130,224,152 (GRCm39)	missense	probably benign	0.02
R4063:Tacc2	UTSW	7	130,330,852 (GRCm39)	missense	probably damaging	0.97
R4410:Tacc2	UTSW	7	130,343,941 (GRCm39)	missense	possibly damaging	0.80
R4434:Tacc2	UTSW	7	130,225,271 (GRCm39)	missense	probably damaging	0.96
R4438:Tacc2	UTSW	7	130,225,271 (GRCm39)	missense	probably damaging	0.96
R4618:Tacc2	UTSW	7	130,227,946 (GRCm39)	missense	probably benign	0.10
R4674:Tacc2	UTSW	7	130,226,591 (GRCm39)	missense	possibly damaging	0.75
R4742:Tacc2	UTSW	7	130,227,697 (GRCm39)	missense	probably benign	0.00
R4934:Tacc2	UTSW	7	130,330,318 (GRCm39)	missense	probably damaging	1.00
R4947:Tacc2	UTSW	7	130,227,629 (GRCm39)	missense	probably damaging	0.98
R4964:Tacc2	UTSW	7	130,330,507 (GRCm39)	missense	probably damaging	1.00
R4966:Tacc2	UTSW	7	130,330,507 (GRCm39)	missense	probably damaging	1.00
R4967:Tacc2	UTSW	7	130,225,678 (GRCm39)	missense	probably damaging	0.99
R5052:Tacc2	UTSW	7	130,336,744 (GRCm39)	missense	probably damaging	1.00
R5276:Tacc2	UTSW	7	130,331,047 (GRCm39)	missense	probably damaging	1.00
R5330:Tacc2	UTSW	7	130,335,258 (GRCm39)	missense	probably damaging	1.00
R5331:Tacc2	UTSW	7	130,335,258 (GRCm39)	missense	probably damaging	1.00
R5556:Tacc2	UTSW	7	130,276,336 (GRCm39)	missense	probably damaging	0.97
R5645:Tacc2	UTSW	7	130,225,781 (GRCm39)	missense	possibly damaging	0.80
R5886:Tacc2	UTSW	7	130,330,850 (GRCm39)	missense	probably benign	0.18
R5996:Tacc2	UTSW	7	130,225,213 (GRCm39)	missense	probably damaging	0.96
R6074:Tacc2	UTSW	7	130,227,165 (GRCm39)	missense	possibly damaging	0.92
R6127:Tacc2	UTSW	7	130,227,845 (GRCm39)	missense	possibly damaging	0.92
R6156:Tacc2	UTSW	7	130,227,494 (GRCm39)	missense	probably damaging	0.98
R6298:Tacc2	UTSW	7	130,228,255 (GRCm39)	missense	probably benign	0.26
R6444:Tacc2	UTSW	7	130,225,142 (GRCm39)	missense	possibly damaging	0.46
R6533:Tacc2	UTSW	7	130,224,567 (GRCm39)	missense	possibly damaging	0.94
R6724:Tacc2	UTSW	7	130,330,492 (GRCm39)	missense	probably damaging	1.00
R7111:Tacc2	UTSW	7	130,330,618 (GRCm39)	missense	probably benign	0.16
R7150:Tacc2	UTSW	7	130,330,807 (GRCm39)	missense	probably benign
R7290:Tacc2	UTSW	7	130,331,103 (GRCm39)	missense	probably benign	0.07
R7404:Tacc2	UTSW	7	130,225,066 (GRCm39)	missense	probably benign	0.22
R7460:Tacc2	UTSW	7	130,226,363 (GRCm39)	missense	probably benign	0.39
R7651:Tacc2	UTSW	7	130,224,884 (GRCm39)	missense	probably benign	0.25
R7666:Tacc2	UTSW	7	130,318,544 (GRCm39)	start gained	probably benign
R7695:Tacc2	UTSW	7	130,330,633 (GRCm39)	missense	probably benign	0.08
R7766:Tacc2	UTSW	7	130,345,328 (GRCm39)	missense	probably damaging	1.00
R7793:Tacc2	UTSW	7	130,224,843 (GRCm39)	missense	probably benign	0.34
R7861:Tacc2	UTSW	7	130,227,161 (GRCm39)	missense	probably benign	0.00
R8204:Tacc2	UTSW	7	130,226,159 (GRCm39)	missense	probably damaging	0.97
R8244:Tacc2	UTSW	7	130,330,406 (GRCm39)	missense	probably damaging	1.00
R8245:Tacc2	UTSW	7	130,331,303 (GRCm39)	missense	probably damaging	1.00
R8283:Tacc2	UTSW	7	130,227,034 (GRCm39)	missense	probably benign	0.02
R8348:Tacc2	UTSW	7	130,225,019 (GRCm39)	missense	possibly damaging	0.84
R8369:Tacc2	UTSW	7	130,223,888 (GRCm39)	missense	probably damaging	0.98
R8381:Tacc2	UTSW	7	130,225,972 (GRCm39)	missense	probably benign	0.00
R8804:Tacc2	UTSW	7	130,294,693 (GRCm39)	missense	probably benign
R8809:Tacc2	UTSW	7	130,276,421 (GRCm39)	missense	possibly damaging	0.94
R8835:Tacc2	UTSW	7	130,228,258 (GRCm39)	missense	probably benign	0.00
R8880:Tacc2	UTSW	7	130,318,564 (GRCm39)	missense	possibly damaging	0.86
R8918:Tacc2	UTSW	7	130,227,823 (GRCm39)	missense	probably benign	0.00
R8936:Tacc2	UTSW	7	130,228,367 (GRCm39)	missense	possibly damaging	0.94
R8953:Tacc2	UTSW	7	130,227,487 (GRCm39)	missense	probably benign	0.00
R9026:Tacc2	UTSW	7	130,225,266 (GRCm39)	missense	probably damaging	1.00
R9193:Tacc2	UTSW	7	130,228,304 (GRCm39)	missense	probably benign	0.04
R9221:Tacc2	UTSW	7	130,226,209 (GRCm39)	missense	probably benign	0.00
R9221:Tacc2	UTSW	7	130,226,058 (GRCm39)	missense	probably damaging	0.98
R9222:Tacc2	UTSW	7	130,227,985 (GRCm39)	missense	probably benign	0.00
R9264:Tacc2	UTSW	7	130,228,533 (GRCm39)	missense	probably damaging	1.00
R9312:Tacc2	UTSW	7	130,223,978 (GRCm39)	missense	probably benign	0.00
R9380:Tacc2	UTSW	7	130,226,771 (GRCm39)	missense	possibly damaging	0.86
R9515:Tacc2	UTSW	7	130,366,041 (GRCm39)	missense	probably damaging	1.00
R9705:Tacc2	UTSW	7	130,361,018 (GRCm39)	missense	probably damaging	1.00
X0010:Tacc2	UTSW	7	130,336,787 (GRCm39)	missense	probably damaging	1.00
Z1176:Tacc2	UTSW	7	130,346,327 (GRCm39)	missense	probably damaging	1.00
Z1176:Tacc2	UTSW	7	130,226,000 (GRCm39)	missense	possibly damaging	0.59
Z1176:Tacc2	UTSW	7	130,225,100 (GRCm39)	missense	probably benign	0.01
Z1177:Tacc2	UTSW	7	130,336,679 (GRCm39)	missense	possibly damaging	0.96
Z1177:Tacc2	UTSW	7	130,227,504 (GRCm39)	missense	probably damaging	0.99
Z1177:Tacc2	UTSW	7	130,226,710 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CTCCCATGGCATTTCAAATGAAAG -3'
(R):5'- TGAGGTAGCTGTGTCAGTCAC -3'

Sequencing Primer
(F):5'- GTTCAGTGGAACCAACTGATG -3'
(R):5'- TCAGTCACATGGGATTCAGC -3'

Posted On

2016-09-06