Incidental Mutation 'R5569:Mprip'
| ID |
435549 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mprip
|
| Ensembl Gene |
ENSMUSG00000005417 |
| Gene Name |
myosin phosphatase Rho interacting protein |
| Synonyms |
p116 Rho interacting protein, p116Rip, Gm34094, RIP3, Rhoip3 |
| MMRRC Submission |
043126-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.523)
|
| Stock # |
R5569 (G1)
|
| Quality Score |
159 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
59552973-59671686 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 59651789 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Valine
at position 1831
(E1831V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071081
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066330]
[ENSMUST00000072031]
[ENSMUST00000108751]
[ENSMUST00000116371]
[ENSMUST00000133861]
|
| AlphaFold |
P97434 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066330
AA Change: E1831V
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000071081
Gene: ENSMUSG00000005417
AA Change: E1831V
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
44 |
152 |
3.33e-10 |
SMART |
|
low complexity region
|
179 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
221 |
234 |
N/A |
INTRINSIC |
|
Blast:PH
|
249 |
320 |
1e-10 |
BLAST |
|
PH
|
351 |
448 |
3.76e-18 |
SMART |
|
low complexity region
|
492 |
501 |
N/A |
INTRINSIC |
|
low complexity region
|
536 |
555 |
N/A |
INTRINSIC |
|
coiled coil region
|
636 |
671 |
N/A |
INTRINSIC |
|
Blast:PAC
|
806 |
848 |
2e-10 |
BLAST |
|
low complexity region
|
1005 |
1023 |
N/A |
INTRINSIC |
|
low complexity region
|
1047 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1114 |
1128 |
N/A |
INTRINSIC |
|
low complexity region
|
1183 |
1200 |
N/A |
INTRINSIC |
|
coiled coil region
|
1267 |
1300 |
N/A |
INTRINSIC |
|
coiled coil region
|
1617 |
1642 |
N/A |
INTRINSIC |
|
coiled coil region
|
1729 |
1779 |
N/A |
INTRINSIC |
|
coiled coil region
|
1899 |
1936 |
N/A |
INTRINSIC |
|
coiled coil region
|
1960 |
2110 |
N/A |
INTRINSIC |
|
coiled coil region
|
2132 |
2206 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000072031
|
| SMART Domains |
Protein: ENSMUSP00000071914
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
44 |
152 |
3.33e-10 |
SMART |
|
low complexity region
|
179 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
221 |
234 |
N/A |
INTRINSIC |
|
Blast:PH
|
254 |
320 |
1e-10 |
BLAST |
|
PH
|
387 |
484 |
3.76e-18 |
SMART |
|
low complexity region
|
528 |
537 |
N/A |
INTRINSIC |
|
low complexity region
|
572 |
591 |
N/A |
INTRINSIC |
|
coiled coil region
|
672 |
707 |
N/A |
INTRINSIC |
|
coiled coil region
|
728 |
878 |
N/A |
INTRINSIC |
|
coiled coil region
|
900 |
974 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108751
|
| SMART Domains |
Protein: ENSMUSP00000104382
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
44 |
152 |
3.33e-10 |
SMART |
|
low complexity region
|
183 |
196 |
N/A |
INTRINSIC |
|
Blast:PH
|
216 |
282 |
1e-10 |
BLAST |
|
PH
|
349 |
446 |
3.76e-18 |
SMART |
|
low complexity region
|
490 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
534 |
553 |
N/A |
INTRINSIC |
|
coiled coil region
|
634 |
669 |
N/A |
INTRINSIC |
|
coiled coil region
|
690 |
840 |
N/A |
INTRINSIC |
|
coiled coil region
|
862 |
936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000116371
|
| SMART Domains |
Protein: ENSMUSP00000112072
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
44 |
152 |
3.33e-10 |
SMART |
|
low complexity region
|
179 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
221 |
234 |
N/A |
INTRINSIC |
|
Blast:PH
|
254 |
320 |
1e-10 |
BLAST |
|
PH
|
387 |
484 |
3.76e-18 |
SMART |
|
low complexity region
|
528 |
537 |
N/A |
INTRINSIC |
|
low complexity region
|
572 |
591 |
N/A |
INTRINSIC |
|
coiled coil region
|
672 |
707 |
N/A |
INTRINSIC |
|
coiled coil region
|
728 |
878 |
N/A |
INTRINSIC |
|
coiled coil region
|
900 |
974 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132620
|
| SMART Domains |
Protein: ENSMUSP00000119422
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
26 |
37 |
N/A |
INTRINSIC |
|
low complexity region
|
68 |
81 |
N/A |
INTRINSIC |
|
Blast:PH
|
101 |
167 |
9e-11 |
BLAST |
|
PH
|
198 |
295 |
3.76e-18 |
SMART |
|
low complexity region
|
339 |
348 |
N/A |
INTRINSIC |
|
low complexity region
|
383 |
402 |
N/A |
INTRINSIC |
|
coiled coil region
|
482 |
517 |
N/A |
INTRINSIC |
|
coiled coil region
|
538 |
688 |
N/A |
INTRINSIC |
|
coiled coil region
|
710 |
784 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000133861
|
| SMART Domains |
Protein: ENSMUSP00000119562
Gene: ENSMUSG00000005417
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
18 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
47 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
89 |
102 |
N/A |
INTRINSIC |
|
low complexity region
|
152 |
162 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
269 |
N/A |
INTRINSIC |
|
PH
|
373 |
470 |
3.76e-18 |
SMART |
|
low complexity region
|
514 |
523 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
577 |
N/A |
INTRINSIC |
|
coiled coil region
|
658 |
693 |
N/A |
INTRINSIC |
|
coiled coil region
|
714 |
864 |
N/A |
INTRINSIC |
|
coiled coil region
|
886 |
960 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000156111
AA Change: E72V
|
| SMART Domains |
Protein: ENSMUSP00000114446
Gene: ENSMUSG00000005417
AA Change: E72V
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
5 |
38 |
1.61e-7 |
PROSPERO |
|
internal_repeat_2
|
9 |
51 |
2.4e-6 |
PROSPERO |
|
internal_repeat_1
|
59 |
92 |
1.61e-7 |
PROSPERO |
|
internal_repeat_2
|
85 |
129 |
2.4e-6 |
PROSPERO |
|
coiled coil region
|
140 |
177 |
N/A |
INTRINSIC |
|
coiled coil region
|
201 |
351 |
N/A |
INTRINSIC |
|
coiled coil region
|
373 |
447 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.3%
- 20x: 94.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acad10 |
A |
G |
5: 121,764,143 (GRCm39) |
S929P |
probably damaging |
Het |
| Ackr3 |
A |
G |
1: 90,142,563 (GRCm39) |
T341A |
probably benign |
Het |
| Acox3 |
A |
G |
5: 35,760,377 (GRCm39) |
Y431C |
probably damaging |
Het |
| Adamtsl2 |
G |
A |
2: 26,992,845 (GRCm39) |
V653M |
probably damaging |
Het |
| Anks6 |
T |
C |
4: 47,045,007 (GRCm39) |
K300E |
probably damaging |
Het |
| Ap5z1 |
A |
T |
5: 142,460,206 (GRCm39) |
D495V |
probably damaging |
Het |
| Atm |
A |
T |
9: 53,427,750 (GRCm39) |
Y453* |
probably null |
Het |
| Atpaf2 |
A |
T |
11: 60,307,706 (GRCm39) |
W11R |
probably damaging |
Het |
| Bhmt1b |
A |
C |
18: 87,775,392 (GRCm39) |
Y305S |
probably damaging |
Het |
| Capn1 |
T |
A |
19: 6,063,690 (GRCm39) |
T129S |
probably benign |
Het |
| Catspere2 |
A |
T |
1: 177,939,162 (GRCm39) |
K678N |
possibly damaging |
Het |
| Cdh17 |
A |
G |
4: 11,816,990 (GRCm39) |
I800M |
probably damaging |
Het |
| Cfap206 |
C |
T |
4: 34,724,892 (GRCm39) |
R69Q |
probably damaging |
Het |
| Cp |
T |
C |
3: 20,033,041 (GRCm39) |
Y623H |
probably damaging |
Het |
| Dcaf5 |
A |
T |
12: 80,386,975 (GRCm39) |
Y384N |
probably damaging |
Het |
| Dhx9 |
A |
T |
1: 153,342,838 (GRCm39) |
C555S |
possibly damaging |
Het |
| Dlg2 |
A |
G |
7: 91,617,388 (GRCm39) |
T317A |
probably benign |
Het |
| Dsp |
C |
T |
13: 38,376,628 (GRCm39) |
T1471I |
probably benign |
Het |
| Ebf1 |
A |
G |
11: 44,883,228 (GRCm39) |
M489V |
possibly damaging |
Het |
| Enpp3 |
T |
C |
10: 24,654,719 (GRCm39) |
D230G |
probably damaging |
Het |
| Eri3 |
T |
C |
4: 117,506,553 (GRCm39) |
M294T |
possibly damaging |
Het |
| Fat1 |
T |
A |
8: 45,492,873 (GRCm39) |
V3842E |
probably damaging |
Het |
| Fermt1 |
T |
A |
2: 132,757,123 (GRCm39) |
Y569F |
possibly damaging |
Het |
| Fscn1 |
A |
G |
5: 142,946,799 (GRCm39) |
D199G |
probably benign |
Het |
| Glce |
A |
G |
9: 61,977,485 (GRCm39) |
V133A |
probably benign |
Het |
| Gtf2h3 |
C |
T |
5: 124,722,360 (GRCm39) |
T121I |
probably benign |
Het |
| Hk1 |
A |
G |
10: 62,122,220 (GRCm39) |
S520P |
probably benign |
Het |
| Ighv12-3 |
A |
G |
12: 114,330,555 (GRCm39) |
V7A |
probably benign |
Het |
| Ighv6-7 |
C |
A |
12: 114,419,476 (GRCm39) |
A43S |
probably damaging |
Het |
| Inf2 |
A |
G |
12: 112,568,113 (GRCm39) |
I222V |
possibly damaging |
Het |
| Kmo |
T |
A |
1: 175,482,688 (GRCm39) |
N337K |
probably benign |
Het |
| Mcf2l |
C |
T |
8: 13,055,481 (GRCm39) |
R611W |
probably damaging |
Het |
| Mipep |
A |
T |
14: 61,040,383 (GRCm39) |
H301L |
probably damaging |
Het |
| Mrgpra3 |
T |
C |
7: 47,239,759 (GRCm39) |
T56A |
probably benign |
Het |
| Mtmr14 |
G |
A |
6: 113,217,246 (GRCm39) |
V53I |
probably damaging |
Het |
| Mycbp2 |
A |
T |
14: 103,372,679 (GRCm39) |
W4056R |
probably damaging |
Het |
| Myl2 |
A |
T |
5: 122,244,783 (GRCm39) |
D151V |
possibly damaging |
Het |
| Myo5c |
A |
T |
9: 75,180,792 (GRCm39) |
D727V |
probably damaging |
Het |
| Or10s1 |
A |
G |
9: 39,985,593 (GRCm39) |
M1V |
probably null |
Het |
| Or1e22 |
A |
T |
11: 73,377,518 (GRCm39) |
I44N |
probably damaging |
Het |
| Or2ag12 |
A |
T |
7: 106,277,690 (GRCm39) |
M1K |
probably null |
Het |
| Or56b1b |
T |
A |
7: 108,164,772 (GRCm39) |
M77L |
probably benign |
Het |
| Or9s18 |
A |
G |
13: 65,300,793 (GRCm39) |
T252A |
possibly damaging |
Het |
| Pabpc1l |
C |
T |
2: 163,885,474 (GRCm39) |
T409I |
probably benign |
Het |
| Pcgf1 |
C |
T |
6: 83,056,686 (GRCm39) |
R81* |
probably null |
Het |
| Pcgf2 |
A |
G |
11: 97,583,193 (GRCm39) |
|
probably null |
Het |
| Phf14 |
T |
A |
6: 11,934,015 (GRCm39) |
N292K |
probably damaging |
Het |
| Plin4 |
T |
C |
17: 56,409,147 (GRCm39) |
T1358A |
probably benign |
Het |
| Pomgnt1 |
T |
C |
4: 116,013,164 (GRCm39) |
S423P |
probably damaging |
Het |
| Prep |
G |
A |
10: 44,973,533 (GRCm39) |
V214I |
probably benign |
Het |
| Ptger1 |
T |
C |
8: 84,394,961 (GRCm39) |
|
probably null |
Het |
| Pus7 |
C |
T |
5: 23,953,832 (GRCm39) |
G415D |
probably benign |
Het |
| Rbm44 |
C |
T |
1: 91,096,460 (GRCm39) |
P940S |
probably damaging |
Het |
| Ripor1 |
A |
T |
8: 106,344,147 (GRCm39) |
D427V |
probably damaging |
Het |
| Rp1 |
A |
G |
1: 4,415,460 (GRCm39) |
I1884T |
probably damaging |
Het |
| Rpl15-ps6 |
T |
C |
15: 52,341,624 (GRCm39) |
|
noncoding transcript |
Het |
| Serinc2 |
T |
C |
4: 130,172,272 (GRCm39) |
R7G |
probably benign |
Het |
| Serpina6 |
A |
C |
12: 103,620,719 (GRCm39) |
F10C |
possibly damaging |
Het |
| Skint5 |
T |
A |
4: 113,545,903 (GRCm39) |
|
probably null |
Het |
| Slc66a3 |
T |
A |
12: 17,045,629 (GRCm39) |
I114F |
possibly damaging |
Het |
| Slc6a4 |
A |
T |
11: 76,914,081 (GRCm39) |
I544F |
possibly damaging |
Het |
| Spdye4b |
T |
C |
5: 143,188,176 (GRCm39) |
M223T |
probably benign |
Het |
| Tbc1d17 |
A |
T |
7: 44,497,755 (GRCm39) |
V39D |
probably damaging |
Het |
| Thbs3 |
T |
A |
3: 89,126,770 (GRCm39) |
Y295N |
probably damaging |
Het |
| Themis |
G |
A |
10: 28,657,887 (GRCm39) |
E152K |
possibly damaging |
Het |
| Tmem131 |
A |
T |
1: 36,838,419 (GRCm39) |
I1502N |
probably benign |
Het |
| Tmem43 |
T |
A |
6: 91,454,336 (GRCm39) |
M41K |
probably benign |
Het |
| Tmprss6 |
A |
C |
15: 78,324,503 (GRCm39) |
W771G |
probably damaging |
Het |
| Trp53tg5 |
T |
C |
2: 164,313,256 (GRCm39) |
T140A |
probably benign |
Het |
| Uchl1 |
A |
G |
5: 66,844,216 (GRCm39) |
E206G |
probably damaging |
Het |
| Vash2 |
A |
G |
1: 190,692,488 (GRCm39) |
V229A |
possibly damaging |
Het |
| Vmn1r192 |
C |
A |
13: 22,371,384 (GRCm39) |
A279S |
possibly damaging |
Het |
| Vmn1r32 |
T |
C |
6: 66,530,156 (GRCm39) |
R207G |
probably damaging |
Het |
| Vmn2r14 |
T |
A |
5: 109,368,261 (GRCm39) |
M244L |
probably benign |
Het |
| Vwa5b2 |
T |
A |
16: 20,414,089 (GRCm39) |
H236Q |
probably damaging |
Het |
| Zfp652 |
C |
T |
11: 95,640,116 (GRCm39) |
P14S |
probably benign |
Het |
| Zfp668 |
G |
A |
7: 127,466,995 (GRCm39) |
R194* |
probably null |
Het |
| Zgrf1 |
G |
T |
3: 127,354,674 (GRCm39) |
V98L |
probably benign |
Het |
|
| Other mutations in Mprip |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00334:Mprip
|
APN |
11 |
59,639,417 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00563:Mprip
|
APN |
11 |
59,643,443 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00905:Mprip
|
APN |
11 |
59,662,994 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL00928:Mprip
|
APN |
11 |
59,635,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01161:Mprip
|
APN |
11 |
59,622,399 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01991:Mprip
|
APN |
11 |
59,645,838 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02491:Mprip
|
APN |
11 |
59,660,857 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL03030:Mprip
|
APN |
11 |
59,631,941 (GRCm39) |
splice site |
probably null |
|
|
IGL03056:Mprip
|
APN |
11 |
59,662,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03293:Mprip
|
APN |
11 |
59,586,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0049:Mprip
|
UTSW |
11 |
59,657,571 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0097:Mprip
|
UTSW |
11 |
59,649,317 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0097:Mprip
|
UTSW |
11 |
59,649,317 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0147:Mprip
|
UTSW |
11 |
59,627,899 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0319:Mprip
|
UTSW |
11 |
59,587,864 (GRCm39) |
splice site |
probably benign |
|
|
R0471:Mprip
|
UTSW |
11 |
59,650,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0539:Mprip
|
UTSW |
11 |
59,631,943 (GRCm39) |
splice site |
probably benign |
|
|
R0627:Mprip
|
UTSW |
11 |
59,660,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0864:Mprip
|
UTSW |
11 |
59,649,587 (GRCm39) |
missense |
probably benign |
|
|
R1218:Mprip
|
UTSW |
11 |
59,634,640 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Mprip
|
UTSW |
11 |
59,650,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Mprip
|
UTSW |
11 |
59,650,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1695:Mprip
|
UTSW |
11 |
59,643,357 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1698:Mprip
|
UTSW |
11 |
59,651,084 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1802:Mprip
|
UTSW |
11 |
59,645,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1837:Mprip
|
UTSW |
11 |
59,657,571 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1862:Mprip
|
UTSW |
11 |
59,649,047 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R2094:Mprip
|
UTSW |
11 |
59,640,334 (GRCm39) |
splice site |
probably benign |
|
|
R2107:Mprip
|
UTSW |
11 |
59,660,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2108:Mprip
|
UTSW |
11 |
59,660,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2510:Mprip
|
UTSW |
11 |
59,640,334 (GRCm39) |
splice site |
probably benign |
|
|
R3003:Mprip
|
UTSW |
11 |
59,618,381 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3115:Mprip
|
UTSW |
11 |
59,656,229 (GRCm39) |
splice site |
probably null |
|
|
R3941:Mprip
|
UTSW |
11 |
59,622,328 (GRCm39) |
splice site |
probably benign |
|
|
R4347:Mprip
|
UTSW |
11 |
59,650,279 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4603:Mprip
|
UTSW |
11 |
59,622,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4807:Mprip
|
UTSW |
11 |
59,648,846 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5011:Mprip
|
UTSW |
11 |
59,650,721 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5338:Mprip
|
UTSW |
11 |
59,651,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5549:Mprip
|
UTSW |
11 |
59,651,644 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5604:Mprip
|
UTSW |
11 |
59,649,293 (GRCm39) |
missense |
probably benign |
|
|
R5615:Mprip
|
UTSW |
11 |
59,649,313 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5846:Mprip
|
UTSW |
11 |
59,649,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5970:Mprip
|
UTSW |
11 |
59,648,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6054:Mprip
|
UTSW |
11 |
59,649,251 (GRCm39) |
missense |
probably benign |
|
|
R6452:Mprip
|
UTSW |
11 |
59,643,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6457:Mprip
|
UTSW |
11 |
59,649,815 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6544:Mprip
|
UTSW |
11 |
59,648,552 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6750:Mprip
|
UTSW |
11 |
59,586,957 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6843:Mprip
|
UTSW |
11 |
59,650,554 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R6851:Mprip
|
UTSW |
11 |
59,649,841 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6867:Mprip
|
UTSW |
11 |
59,640,456 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7002:Mprip
|
UTSW |
11 |
59,652,016 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7023:Mprip
|
UTSW |
11 |
59,628,215 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7764:Mprip
|
UTSW |
11 |
59,655,242 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7765:Mprip
|
UTSW |
11 |
59,649,047 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7828:Mprip
|
UTSW |
11 |
59,627,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7866:Mprip
|
UTSW |
11 |
59,643,756 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R7911:Mprip
|
UTSW |
11 |
59,651,681 (GRCm39) |
missense |
|
|
|
R7979:Mprip
|
UTSW |
11 |
59,657,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8292:Mprip
|
UTSW |
11 |
59,650,340 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8481:Mprip
|
UTSW |
11 |
59,648,982 (GRCm39) |
nonsense |
probably null |
|
|
R8717:Mprip
|
UTSW |
11 |
59,650,526 (GRCm39) |
missense |
probably benign |
|
|
R8810:Mprip
|
UTSW |
11 |
59,587,851 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R8981:Mprip
|
UTSW |
11 |
59,622,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9214:Mprip
|
UTSW |
11 |
59,650,901 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9245:Mprip
|
UTSW |
11 |
59,628,403 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9748:Mprip
|
UTSW |
11 |
59,656,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Mprip
|
UTSW |
11 |
59,650,310 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1176:Mprip
|
UTSW |
11 |
59,628,230 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
Z1177:Mprip
|
UTSW |
11 |
59,648,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GACCATCAGCAGAGATGTCTAC -3'
(R):5'- TCCTGGATACGTTCTCGCAG -3'
Sequencing Primer
(F):5'- CCATCAGCAGAGATGTCTACAAGAAG -3'
(R):5'- ACATGGACTCGGCCTCATC -3'
|
| Posted On |
2016-10-24 |
Incidental Mutation