Mutagenetix > Incidental Mutation

Incidental Mutation 'R0496:Pkd1l1'

43952

Institutional Source

Beutler Lab

Gene Symbol

Pkd1l1

Ensembl Gene

ENSMUSG00000046634

Gene Name

polycystic kidney disease 1 like 1

Synonyms

MMRRC Submission

038692-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R0496 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

8782025-8924365 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 8879430 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Asparagine at position 474 (H474N)

Ref Sequence

ENSEMBL: ENSMUSP00000136518 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000178195]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000154153
AA Change: H924N

SMART Domains

Protein: ENSMUSP00000120803
Gene: ENSMUSG00000046634
AA Change: H924N

Domain	Start	End	E-Value	Type
low complexity region	172	184	N/A	INTRINSIC
PKD	205	287	2.9e0	SMART
PKD	291	369	1.42e-9	SMART
Pfam:REJ	398	1001	1.7e-45	PFAM
low complexity region	1208	1218	N/A	INTRINSIC
GPS	1370	1413	1.21e-1	SMART
transmembrane domain	1434	1451	N/A	INTRINSIC
LH2	1479	1598	2.94e-3	SMART
transmembrane domain	1640	1659	N/A	INTRINSIC
transmembrane domain	1679	1701	N/A	INTRINSIC
transmembrane domain	1817	1839	N/A	INTRINSIC
transmembrane domain	1854	1876	N/A	INTRINSIC
Pfam:PKD_channel	2109	2339	1.5e-23	PFAM
transmembrane domain	2381	2403	N/A	INTRINSIC
low complexity region	2436	2449	N/A	INTRINSIC
low complexity region	2458	2469	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000178195
AA Change: H474N

PolyPhen 2 Score 0.961 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000136518
Gene: ENSMUSG00000046634
AA Change: H474N

Domain	Start	End	E-Value	Type
Pfam:REJ	3	552	3.3e-41	PFAM
low complexity region	757	767	N/A	INTRINSIC
Blast:GPS	919	965	2e-13	BLAST
transmembrane domain	983	1000	N/A	INTRINSIC
Pfam:PLAT	1030	1145	7.2e-14	PFAM
transmembrane domain	1189	1208	N/A	INTRINSIC
transmembrane domain	1228	1250	N/A	INTRINSIC
transmembrane domain	1366	1388	N/A	INTRINSIC
transmembrane domain	1403	1425	N/A	INTRINSIC
Pfam:PKD_channel	1658	1889	2e-25	PFAM
transmembrane domain	1930	1952	N/A	INTRINSIC
low complexity region	1985	1998	N/A	INTRINSIC
low complexity region	2007	2018	N/A	INTRINSIC

Meta Mutation Damage Score

0.2700

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.3%
20x: 92.6%

Validation Efficiency

98% (99/101)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for an ENU induced point mutation display lethality throughout fetal growth and development with abnormalities in left right patterning and heterotaxia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 97 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110002E22Rik	A	G	3: 137,774,005 (GRCm39)	K1065E	probably damaging	Het
4933402N03Rik	T	C	7: 130,747,860 (GRCm39)	N44S	probably benign	Het
Abca13	A	G	11: 9,241,701 (GRCm39)	D1188G	probably benign	Het
Abcb11	C	T	2: 69,108,228 (GRCm39)		probably benign	Het
Abcc8	A	T	7: 45,758,244 (GRCm39)	I1274N	probably damaging	Het
Adamtsl1	G	A	4: 86,259,435 (GRCm39)	C827Y	probably damaging	Het
Agap3	T	A	5: 24,706,241 (GRCm39)	V369E	probably damaging	Het
Ankrd13b	G	A	11: 77,363,867 (GRCm39)	R195C	probably damaging	Het
Ap3b1	A	G	13: 94,609,446 (GRCm39)		probably benign	Het
Arhgef40	A	T	14: 52,242,364 (GRCm39)		probably benign	Het
Atad5	A	G	11: 79,991,182 (GRCm39)	I692V	probably benign	Het
Atp5f1b	G	T	10: 127,922,043 (GRCm39)	R310L	possibly damaging	Het
AY358078	A	T	14: 52,040,989 (GRCm39)	M103L	unknown	Het
Bcl9l	T	G	9: 44,420,815 (GRCm39)	V1370G	probably benign	Het
Bglap3	T	A	3: 88,276,444 (GRCm39)	Q38L	probably damaging	Het
Bltp1	A	G	3: 37,041,784 (GRCm39)	T2721A	probably damaging	Het
Ccn2	G	T	10: 24,473,413 (GRCm39)	M317I	possibly damaging	Het
Cd38	T	C	5: 44,026,233 (GRCm39)	F6L	probably damaging	Het
Cela3a	A	C	4: 137,131,779 (GRCm39)	V138G	probably damaging	Het
Cemip2	A	T	19: 21,774,709 (GRCm39)	N117I	possibly damaging	Het
Clvs1	T	A	4: 9,424,241 (GRCm39)	I229N	probably damaging	Het
Cpne1	G	A	2: 155,921,339 (GRCm39)	H16Y	probably damaging	Het
Ctc1	T	C	11: 68,926,333 (GRCm39)	L1069P	probably damaging	Het
Dgkd	G	A	1: 87,864,622 (GRCm39)	S996N	probably null	Het
Dnah9	A	T	11: 65,965,961 (GRCm39)	M1685K	probably null	Het
Dnajb12	C	T	10: 59,715,623 (GRCm39)	R42*	probably null	Het
Dock5	T	C	14: 68,054,967 (GRCm39)	Q633R	probably damaging	Het
Dync2h1	A	G	9: 7,155,180 (GRCm39)	M868T	probably benign	Het
Enpp1	G	T	10: 24,547,950 (GRCm39)	H208Q	probably benign	Het
Epha7	T	A	4: 28,821,292 (GRCm39)	D152E	probably damaging	Het
Fancd2	T	C	6: 113,532,091 (GRCm39)		probably benign	Het
Gart	G	A	16: 91,419,925 (GRCm39)		probably benign	Het
Gm10964	A	T	3: 103,646,745 (GRCm39)		probably null	Het
Gpbar1	T	C	1: 74,318,140 (GRCm39)	F128L	probably benign	Het
Gsx2	T	A	5: 75,237,726 (GRCm39)	M226K	probably benign	Het
Gucd1	T	C	10: 75,347,100 (GRCm39)	D50G	possibly damaging	Het
Has1	A	G	17: 18,064,008 (GRCm39)	Y544H	probably benign	Het
Hc	A	T	2: 34,903,583 (GRCm39)	Y1024N	probably damaging	Het
Hoxa13	CCG	CCGCG	6: 52,237,618 (GRCm39)		probably null	Het
Ift122	T	A	6: 115,882,863 (GRCm39)	H659Q	probably benign	Het
Itga2	T	C	13: 114,990,435 (GRCm39)	Q902R	probably benign	Het
Itgb2l	T	C	16: 96,235,901 (GRCm39)	K181E	possibly damaging	Het
Jak3	A	T	8: 72,135,041 (GRCm39)	H558L	probably damaging	Het
Kcnh8	A	G	17: 53,032,886 (GRCm39)	T58A	probably benign	Het
Klhl6	GT	G	16: 19,775,716 (GRCm39)	279	probably null	Het
Krt33a	C	T	11: 99,903,155 (GRCm39)		probably benign	Het
Magi2	A	T	5: 20,866,357 (GRCm39)		probably benign	Het
Map4	G	A	9: 109,868,918 (GRCm39)		probably benign	Het
Map4k4	T	A	1: 40,045,982 (GRCm39)	S754T	probably damaging	Het
Mapk8ip3	A	G	17: 25,133,424 (GRCm39)		probably benign	Het
Mib1	A	G	18: 10,804,773 (GRCm39)	S918G	probably benign	Het
Mipol1	T	A	12: 57,503,963 (GRCm39)	V377D	probably damaging	Het
Mlh1	T	C	9: 111,070,624 (GRCm39)	T364A	probably benign	Het
Mta1	C	T	12: 113,094,941 (GRCm39)	Q400*	probably null	Het
Mthfd1l	C	G	10: 4,040,006 (GRCm39)	R806G	probably benign	Het
Myh13	C	A	11: 67,239,641 (GRCm39)	N730K	probably damaging	Het
Myom1	A	G	17: 71,391,301 (GRCm39)	K937E	probably damaging	Het
Naxd	T	C	8: 11,560,224 (GRCm39)		probably benign	Het
Negr1	G	T	3: 156,721,904 (GRCm39)	K159N	probably damaging	Het
Nwd2	G	T	5: 63,963,686 (GRCm39)	W1090L	probably damaging	Het
Or1e1f	T	C	11: 73,855,706 (GRCm39)	S91P	probably benign	Het
Or2j3	A	G	17: 38,615,549 (GRCm39)	S268P	probably damaging	Het
Or51v14	C	T	7: 103,261,204 (GRCm39)	A119T	probably benign	Het
Or52r1c	T	C	7: 102,734,797 (GRCm39)	I19T	probably damaging	Het
Or5d41	A	T	2: 88,054,499 (GRCm39)	Y292*	probably null	Het
Pcsk6	G	A	7: 65,576,997 (GRCm39)	S58N	probably benign	Het
Pdzrn3	G	A	6: 101,127,531 (GRCm39)	T1045I	possibly damaging	Het
Pitrm1	T	C	13: 6,618,750 (GRCm39)	L641P	probably damaging	Het
Pltp	A	G	2: 164,694,381 (GRCm39)		probably benign	Het
Qtrt1	C	T	9: 21,330,844 (GRCm39)	T324M	probably benign	Het
Racgap1	A	T	15: 99,537,713 (GRCm39)		probably benign	Het
Rhbg	A	G	3: 88,161,805 (GRCm39)	V50A	probably benign	Het
Rnf135	G	A	11: 80,074,776 (GRCm39)	V12M	probably damaging	Het
Rnf7l	G	T	10: 63,257,381 (GRCm39)	C46*	probably null	Het
Rufy2	T	C	10: 62,828,949 (GRCm39)	V117A	probably damaging	Het
Safb	A	G	17: 56,912,630 (GRCm39)	M866V	probably benign	Het
Slc35c2	G	T	2: 165,122,735 (GRCm39)	T183K	probably damaging	Het
Slc39a7	A	G	17: 34,248,512 (GRCm39)	L377P	probably damaging	Het
Slit1	G	A	19: 41,596,750 (GRCm39)		probably benign	Het
Spaca9	G	A	2: 28,583,022 (GRCm39)	H133Y	probably damaging	Het
Spout1	A	G	2: 30,064,983 (GRCm39)	F339S	probably benign	Het
St6gal2	A	G	17: 55,789,015 (GRCm39)	I16M	probably damaging	Het
Stat2	T	C	10: 128,112,378 (GRCm39)	M6T	probably benign	Het
Swt1	T	A	1: 151,287,021 (GRCm39)	H157L	probably benign	Het
Syne2	A	G	12: 76,085,714 (GRCm39)	N147D	possibly damaging	Het
Tmem222	A	T	4: 133,004,902 (GRCm39)	M45K	possibly damaging	Het
Tmem30a	T	A	9: 79,684,567 (GRCm39)	H95L	probably damaging	Het
Tns3	A	C	11: 8,497,262 (GRCm39)		probably benign	Het
Trpm3	A	G	19: 22,676,142 (GRCm39)	I103V	probably benign	Het
Ube2n	T	C	10: 95,377,206 (GRCm39)	F57S	probably benign	Het
Vil1	T	C	1: 74,460,499 (GRCm39)	S219P	possibly damaging	Het
Wdfy4	A	G	14: 32,862,695 (GRCm39)		probably benign	Het
Wdr7	T	C	18: 63,924,914 (GRCm39)	S966P	probably benign	Het
Wnt8a	A	G	18: 34,677,900 (GRCm39)	N103D	probably damaging	Het
Zfp523	G	A	17: 28,419,419 (GRCm39)	E186K	possibly damaging	Het
Zfp791	A	T	8: 85,836,609 (GRCm39)	D418E	probably benign	Het
Zscan20	A	G	4: 128,485,682 (GRCm39)	V192A	probably benign	Het

Other mutations in Pkd1l1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00093:Pkd1l1	APN	11	8,911,971 (GRCm39)	missense	unknown
IGL00156:Pkd1l1	APN	11	8,900,515 (GRCm39)	missense	probably damaging	1.00
IGL00161:Pkd1l1	APN	11	8,879,353 (GRCm39)	critical splice donor site	probably null
IGL00489:Pkd1l1	APN	11	8,784,773 (GRCm39)	critical splice donor site	probably null
IGL00495:Pkd1l1	APN	11	8,818,493 (GRCm39)	missense	probably benign	0.34
IGL00983:Pkd1l1	APN	11	8,794,585 (GRCm39)	missense	probably benign
IGL01071:Pkd1l1	APN	11	8,798,921 (GRCm39)	missense	probably benign	0.00
IGL01093:Pkd1l1	APN	11	8,851,345 (GRCm39)	missense	probably benign	0.06
IGL01295:Pkd1l1	APN	11	8,883,685 (GRCm39)	missense	possibly damaging	0.93
IGL01311:Pkd1l1	APN	11	8,851,174 (GRCm39)	missense	possibly damaging	0.53
IGL01412:Pkd1l1	APN	11	8,900,409 (GRCm39)	missense	possibly damaging	0.73
IGL01978:Pkd1l1	APN	11	8,911,336 (GRCm39)	missense	unknown
IGL01999:Pkd1l1	APN	11	8,786,291 (GRCm39)	missense	probably benign
IGL02080:Pkd1l1	APN	11	8,911,345 (GRCm39)	missense	unknown
IGL02106:Pkd1l1	APN	11	8,783,800 (GRCm39)	missense	probably damaging	1.00
IGL02216:Pkd1l1	APN	11	8,784,897 (GRCm39)	missense	probably damaging	0.96
IGL02305:Pkd1l1	APN	11	8,852,467 (GRCm39)	missense	probably benign
IGL02337:Pkd1l1	APN	11	8,892,079 (GRCm39)	missense	probably damaging	1.00
IGL02576:Pkd1l1	APN	11	8,794,560 (GRCm39)	missense	possibly damaging	0.61
IGL02704:Pkd1l1	APN	11	8,784,910 (GRCm39)	missense	probably benign	0.00
IGL02814:Pkd1l1	APN	11	8,852,582 (GRCm39)	missense	probably benign	0.01
IGL02904:Pkd1l1	APN	11	8,818,450 (GRCm39)	splice site	probably benign
IGL02972:Pkd1l1	APN	11	8,813,908 (GRCm39)	missense	probably damaging	0.99
IGL03091:Pkd1l1	APN	11	8,805,564 (GRCm39)	missense	probably damaging	1.00
IGL03113:Pkd1l1	APN	11	8,784,793 (GRCm39)	missense	probably benign	0.20
IGL03210:Pkd1l1	APN	11	8,915,127 (GRCm39)	missense	unknown
PIT4581001:Pkd1l1	UTSW	11	8,866,298 (GRCm39)	frame shift	probably null
R0020:Pkd1l1	UTSW	11	8,825,765 (GRCm39)	splice site	probably benign
R0020:Pkd1l1	UTSW	11	8,825,765 (GRCm39)	splice site	probably benign
R0547:Pkd1l1	UTSW	11	8,786,448 (GRCm39)	splice site	probably benign
R0582:Pkd1l1	UTSW	11	8,881,699 (GRCm39)	splice site	probably benign
R0761:Pkd1l1	UTSW	11	8,804,375 (GRCm39)	missense	probably damaging	1.00
R0969:Pkd1l1	UTSW	11	8,886,898 (GRCm39)	missense	probably damaging	1.00
R1348:Pkd1l1	UTSW	11	8,784,806 (GRCm39)	missense	probably benign	0.18
R1366:Pkd1l1	UTSW	11	8,891,038 (GRCm39)	splice site	probably benign
R1401:Pkd1l1	UTSW	11	8,804,487 (GRCm39)	nonsense	probably null
R1444:Pkd1l1	UTSW	11	8,804,386 (GRCm39)	missense	probably damaging	1.00
R1445:Pkd1l1	UTSW	11	8,820,313 (GRCm39)	missense	probably benign	0.00
R1463:Pkd1l1	UTSW	11	8,866,302 (GRCm39)	missense	probably damaging	1.00
R1496:Pkd1l1	UTSW	11	8,891,077 (GRCm39)	missense	possibly damaging	0.95
R1542:Pkd1l1	UTSW	11	8,824,179 (GRCm39)	missense	possibly damaging	0.82
R1543:Pkd1l1	UTSW	11	8,851,200 (GRCm39)	missense	probably damaging	1.00
R1619:Pkd1l1	UTSW	11	8,900,413 (GRCm39)	missense	probably damaging	0.98
R1875:Pkd1l1	UTSW	11	8,794,670 (GRCm39)	splice site	probably benign
R1929:Pkd1l1	UTSW	11	8,786,197 (GRCm39)	splice site	probably benign
R1958:Pkd1l1	UTSW	11	8,824,161 (GRCm39)	missense	probably benign	0.01
R2223:Pkd1l1	UTSW	11	8,900,422 (GRCm39)	missense	probably benign
R2223:Pkd1l1	UTSW	11	8,839,063 (GRCm39)	missense	probably benign	0.18
R2264:Pkd1l1	UTSW	11	8,829,112 (GRCm39)	missense	probably damaging	0.97
R2349:Pkd1l1	UTSW	11	8,776,819 (GRCm39)	splice site	probably null
R2431:Pkd1l1	UTSW	11	8,897,197 (GRCm39)	missense	probably damaging	0.99
R2483:Pkd1l1	UTSW	11	8,912,701 (GRCm39)	missense	probably damaging	1.00
R2517:Pkd1l1	UTSW	11	8,908,900 (GRCm39)	missense	unknown
R2888:Pkd1l1	UTSW	11	8,897,251 (GRCm39)	missense	probably damaging	1.00
R2965:Pkd1l1	UTSW	11	8,824,236 (GRCm39)	missense	probably damaging	1.00
R3123:Pkd1l1	UTSW	11	8,923,021 (GRCm39)	missense	unknown
R3153:Pkd1l1	UTSW	11	8,817,207 (GRCm39)	missense	probably benign	0.01
R3840:Pkd1l1	UTSW	11	8,839,050 (GRCm39)	missense	probably damaging	1.00
R3855:Pkd1l1	UTSW	11	8,915,047 (GRCm39)	critical splice donor site	probably null
R3880:Pkd1l1	UTSW	11	8,911,983 (GRCm39)	missense	unknown
R3970:Pkd1l1	UTSW	11	8,824,218 (GRCm39)	missense	probably damaging	1.00
R4195:Pkd1l1	UTSW	11	8,859,929 (GRCm39)	missense	probably damaging	1.00
R4196:Pkd1l1	UTSW	11	8,859,929 (GRCm39)	missense	probably damaging	1.00
R4246:Pkd1l1	UTSW	11	8,815,543 (GRCm39)	missense	possibly damaging	0.51
R4247:Pkd1l1	UTSW	11	8,815,543 (GRCm39)	missense	possibly damaging	0.51
R4249:Pkd1l1	UTSW	11	8,815,543 (GRCm39)	missense	possibly damaging	0.51
R4250:Pkd1l1	UTSW	11	8,815,543 (GRCm39)	missense	possibly damaging	0.51
R4593:Pkd1l1	UTSW	11	8,851,253 (GRCm39)	missense	probably damaging	0.97
R4609:Pkd1l1	UTSW	11	8,908,964 (GRCm39)	missense	unknown
R4797:Pkd1l1	UTSW	11	8,911,340 (GRCm39)	missense	unknown
R4910:Pkd1l1	UTSW	11	8,879,360 (GRCm39)	missense	possibly damaging	0.50
R4940:Pkd1l1	UTSW	11	8,794,585 (GRCm39)	missense	probably benign
R5084:Pkd1l1	UTSW	11	8,892,004 (GRCm39)	missense	probably benign	0.05
R5147:Pkd1l1	UTSW	11	8,799,003 (GRCm39)	missense	possibly damaging	0.71
R5360:Pkd1l1	UTSW	11	8,829,204 (GRCm39)	missense	probably benign
R5483:Pkd1l1	UTSW	11	8,851,141 (GRCm39)	critical splice donor site	probably null
R5604:Pkd1l1	UTSW	11	8,783,877 (GRCm39)	missense	probably damaging	0.98
R5642:Pkd1l1	UTSW	11	8,829,202 (GRCm39)	missense	probably damaging	1.00
R5652:Pkd1l1	UTSW	11	8,859,889 (GRCm39)	missense	probably benign	0.03
R5751:Pkd1l1	UTSW	11	8,817,204 (GRCm39)	missense	possibly damaging	0.45
R5761:Pkd1l1	UTSW	11	8,866,301 (GRCm39)	missense	probably damaging	1.00
R5800:Pkd1l1	UTSW	11	8,811,302 (GRCm39)	missense	probably benign
R5874:Pkd1l1	UTSW	11	8,858,688 (GRCm39)	missense	probably damaging	1.00
R5897:Pkd1l1	UTSW	11	8,829,176 (GRCm39)	missense	probably benign	0.03
R5913:Pkd1l1	UTSW	11	8,813,849 (GRCm39)	missense	probably benign	0.00
R5930:Pkd1l1	UTSW	11	8,908,969 (GRCm39)	missense	unknown
R6000:Pkd1l1	UTSW	11	8,900,427 (GRCm39)	missense	probably benign	0.00
R6005:Pkd1l1	UTSW	11	8,807,113 (GRCm39)	missense	probably damaging	1.00
R6013:Pkd1l1	UTSW	11	8,819,452 (GRCm39)	splice site	probably null
R6027:Pkd1l1	UTSW	11	8,866,272 (GRCm39)	nonsense	probably null
R6028:Pkd1l1	UTSW	11	8,786,267 (GRCm39)	missense	probably benign	0.06
R6129:Pkd1l1	UTSW	11	8,818,543 (GRCm39)	missense	probably benign	0.00
R6182:Pkd1l1	UTSW	11	8,815,555 (GRCm39)	missense	probably benign	0.36
R6226:Pkd1l1	UTSW	11	8,851,287 (GRCm39)	missense	probably benign	0.00
R6257:Pkd1l1	UTSW	11	8,892,195 (GRCm39)	missense	probably benign	0.22
R6340:Pkd1l1	UTSW	11	8,794,649 (GRCm39)	missense	probably benign	0.09
R6478:Pkd1l1	UTSW	11	8,813,911 (GRCm39)	missense	probably benign	0.00
R6558:Pkd1l1	UTSW	11	8,839,052 (GRCm39)	missense	probably benign	0.00
R6750:Pkd1l1	UTSW	11	8,923,217 (GRCm39)	missense	unknown
R6987:Pkd1l1	UTSW	11	8,852,575 (GRCm39)	missense	probably benign	0.01
R6996:Pkd1l1	UTSW	11	8,799,046 (GRCm39)	missense	probably damaging	1.00
R7139:Pkd1l1	UTSW	11	8,840,737 (GRCm39)	missense
R7224:Pkd1l1	UTSW	11	8,895,241 (GRCm39)	missense
R7244:Pkd1l1	UTSW	11	8,821,771 (GRCm39)	missense
R7265:Pkd1l1	UTSW	11	8,879,402 (GRCm39)	missense
R7358:Pkd1l1	UTSW	11	8,895,202 (GRCm39)	missense
R7387:Pkd1l1	UTSW	11	8,851,203 (GRCm39)	missense
R7414:Pkd1l1	UTSW	11	8,866,267 (GRCm39)	missense
R7459:Pkd1l1	UTSW	11	8,852,428 (GRCm39)	missense
R7478:Pkd1l1	UTSW	11	8,879,441 (GRCm39)	missense
R7485:Pkd1l1	UTSW	11	8,915,148 (GRCm39)	missense
R7490:Pkd1l1	UTSW	11	8,866,265 (GRCm39)	missense
R7644:Pkd1l1	UTSW	11	8,825,758 (GRCm39)	missense
R7647:Pkd1l1	UTSW	11	8,897,296 (GRCm39)	missense
R7676:Pkd1l1	UTSW	11	8,912,708 (GRCm39)	missense
R7687:Pkd1l1	UTSW	11	8,804,390 (GRCm39)	missense
R7699:Pkd1l1	UTSW	11	8,915,142 (GRCm39)	missense
R7922:Pkd1l1	UTSW	11	8,859,857 (GRCm39)	missense
R7922:Pkd1l1	UTSW	11	8,799,013 (GRCm39)	missense
R7980:Pkd1l1	UTSW	11	8,804,375 (GRCm39)	missense	probably damaging	1.00
R7993:Pkd1l1	UTSW	11	8,895,262 (GRCm39)	missense
R8052:Pkd1l1	UTSW	11	8,897,315 (GRCm39)	missense
R8125:Pkd1l1	UTSW	11	8,897,241 (GRCm39)	missense	probably damaging	1.00
R8420:Pkd1l1	UTSW	11	8,820,277 (GRCm39)	nonsense	probably null
R8675:Pkd1l1	UTSW	11	8,798,916 (GRCm39)	critical splice donor site	probably null
R8683:Pkd1l1	UTSW	11	8,821,805 (GRCm39)	missense
R8709:Pkd1l1	UTSW	11	8,805,567 (GRCm39)	missense
R8711:Pkd1l1	UTSW	11	8,815,550 (GRCm39)	missense
R8725:Pkd1l1	UTSW	11	8,911,482 (GRCm39)	missense
R8733:Pkd1l1	UTSW	11	8,883,657 (GRCm39)	missense
R8822:Pkd1l1	UTSW	11	8,806,312 (GRCm39)	missense
R8871:Pkd1l1	UTSW	11	8,900,503 (GRCm39)	missense
R9009:Pkd1l1	UTSW	11	8,881,552 (GRCm39)	missense
R9099:Pkd1l1	UTSW	11	8,922,986 (GRCm39)	missense
R9119:Pkd1l1	UTSW	11	8,829,107 (GRCm39)	missense
R9150:Pkd1l1	UTSW	11	8,786,256 (GRCm39)	missense
R9314:Pkd1l1	UTSW	11	8,829,153 (GRCm39)	missense
R9341:Pkd1l1	UTSW	11	8,911,305 (GRCm39)	missense
R9341:Pkd1l1	UTSW	11	8,786,399 (GRCm39)	missense
R9343:Pkd1l1	UTSW	11	8,911,305 (GRCm39)	missense
R9343:Pkd1l1	UTSW	11	8,786,399 (GRCm39)	missense
R9392:Pkd1l1	UTSW	11	8,794,567 (GRCm39)	missense
R9424:Pkd1l1	UTSW	11	8,820,091 (GRCm39)	missense
R9496:Pkd1l1	UTSW	11	8,783,773 (GRCm39)	critical splice donor site	probably null
R9504:Pkd1l1	UTSW	11	8,815,631 (GRCm39)	missense
R9563:Pkd1l1	UTSW	11	8,815,502 (GRCm39)	missense
R9570:Pkd1l1	UTSW	11	8,840,697 (GRCm39)	missense
R9585:Pkd1l1	UTSW	11	8,804,390 (GRCm39)	missense
R9618:Pkd1l1	UTSW	11	8,911,420 (GRCm39)	missense
R9709:Pkd1l1	UTSW	11	8,799,016 (GRCm39)	missense	probably damaging	0.98
R9741:Pkd1l1	UTSW	11	8,897,224 (GRCm39)	missense
R9801:Pkd1l1	UTSW	11	8,908,964 (GRCm39)	nonsense	probably null
X0024:Pkd1l1	UTSW	11	8,900,413 (GRCm39)	missense	probably benign	0.01
X0063:Pkd1l1	UTSW	11	8,879,430 (GRCm39)	missense	probably damaging	0.96
X0065:Pkd1l1	UTSW	11	8,859,921 (GRCm39)	missense	probably benign	0.10
Z1176:Pkd1l1	UTSW	11	8,776,801 (GRCm39)	missense
Z1177:Pkd1l1	UTSW	11	8,895,208 (GRCm39)	missense

Predicted Primers

Posted On

2013-05-29