Incidental Mutation 'R0496:Myh13'
| ID |
43955 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh13
|
| Ensembl Gene |
ENSMUSG00000060180 |
| Gene Name |
myosin, heavy polypeptide 13, skeletal muscle |
| Synonyms |
EO Myosin, MyHC-eo, extraocular myosin |
| MMRRC Submission |
038692-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.157)
|
| Stock # |
R0496 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
67217929-67262413 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 67239641 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 730
(N730K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000137731
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000081911]
[ENSMUST00000108684]
[ENSMUST00000180845]
|
| AlphaFold |
B1AR69 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000081911
AA Change: N730K
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000080584
Gene: ENSMUSG00000060180
AA Change: N730K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
74 |
8e-13 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
Pfam:Myosin_tail_1
|
847 |
1928 |
4.6e-159 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108684
AA Change: N730K
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000104324
Gene: ENSMUSG00000060180
AA Change: N730K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
2.8e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
low complexity region
|
847 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
940 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000180845
AA Change: N730K
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000137731
Gene: ENSMUSG00000060180
AA Change: N730K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
2.8e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
low complexity region
|
847 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
940 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.6%
|
| Validation Efficiency |
98% (99/101) |
| Allele List at MGI |
All alleles(4) : Gene trapped(4) |
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
A |
G |
3: 137,774,005 (GRCm39) |
K1065E |
probably damaging |
Het |
| 4933402N03Rik |
T |
C |
7: 130,747,860 (GRCm39) |
N44S |
probably benign |
Het |
| Abca13 |
A |
G |
11: 9,241,701 (GRCm39) |
D1188G |
probably benign |
Het |
| Abcb11 |
C |
T |
2: 69,108,228 (GRCm39) |
|
probably benign |
Het |
| Abcc8 |
A |
T |
7: 45,758,244 (GRCm39) |
I1274N |
probably damaging |
Het |
| Adamtsl1 |
G |
A |
4: 86,259,435 (GRCm39) |
C827Y |
probably damaging |
Het |
| Agap3 |
T |
A |
5: 24,706,241 (GRCm39) |
V369E |
probably damaging |
Het |
| Ankrd13b |
G |
A |
11: 77,363,867 (GRCm39) |
R195C |
probably damaging |
Het |
| Ap3b1 |
A |
G |
13: 94,609,446 (GRCm39) |
|
probably benign |
Het |
| Arhgef40 |
A |
T |
14: 52,242,364 (GRCm39) |
|
probably benign |
Het |
| Atad5 |
A |
G |
11: 79,991,182 (GRCm39) |
I692V |
probably benign |
Het |
| Atp5f1b |
G |
T |
10: 127,922,043 (GRCm39) |
R310L |
possibly damaging |
Het |
| AY358078 |
A |
T |
14: 52,040,989 (GRCm39) |
M103L |
unknown |
Het |
| Bcl9l |
T |
G |
9: 44,420,815 (GRCm39) |
V1370G |
probably benign |
Het |
| Bglap3 |
T |
A |
3: 88,276,444 (GRCm39) |
Q38L |
probably damaging |
Het |
| Bltp1 |
A |
G |
3: 37,041,784 (GRCm39) |
T2721A |
probably damaging |
Het |
| Ccn2 |
G |
T |
10: 24,473,413 (GRCm39) |
M317I |
possibly damaging |
Het |
| Cd38 |
T |
C |
5: 44,026,233 (GRCm39) |
F6L |
probably damaging |
Het |
| Cela3a |
A |
C |
4: 137,131,779 (GRCm39) |
V138G |
probably damaging |
Het |
| Cemip2 |
A |
T |
19: 21,774,709 (GRCm39) |
N117I |
possibly damaging |
Het |
| Clvs1 |
T |
A |
4: 9,424,241 (GRCm39) |
I229N |
probably damaging |
Het |
| Cpne1 |
G |
A |
2: 155,921,339 (GRCm39) |
H16Y |
probably damaging |
Het |
| Ctc1 |
T |
C |
11: 68,926,333 (GRCm39) |
L1069P |
probably damaging |
Het |
| Dgkd |
G |
A |
1: 87,864,622 (GRCm39) |
S996N |
probably null |
Het |
| Dnah9 |
A |
T |
11: 65,965,961 (GRCm39) |
M1685K |
probably null |
Het |
| Dnajb12 |
C |
T |
10: 59,715,623 (GRCm39) |
R42* |
probably null |
Het |
| Dock5 |
T |
C |
14: 68,054,967 (GRCm39) |
Q633R |
probably damaging |
Het |
| Dync2h1 |
A |
G |
9: 7,155,180 (GRCm39) |
M868T |
probably benign |
Het |
| Enpp1 |
G |
T |
10: 24,547,950 (GRCm39) |
H208Q |
probably benign |
Het |
| Epha7 |
T |
A |
4: 28,821,292 (GRCm39) |
D152E |
probably damaging |
Het |
| Fancd2 |
T |
C |
6: 113,532,091 (GRCm39) |
|
probably benign |
Het |
| Gart |
G |
A |
16: 91,419,925 (GRCm39) |
|
probably benign |
Het |
| Gm10964 |
A |
T |
3: 103,646,745 (GRCm39) |
|
probably null |
Het |
| Gpbar1 |
T |
C |
1: 74,318,140 (GRCm39) |
F128L |
probably benign |
Het |
| Gsx2 |
T |
A |
5: 75,237,726 (GRCm39) |
M226K |
probably benign |
Het |
| Gucd1 |
T |
C |
10: 75,347,100 (GRCm39) |
D50G |
possibly damaging |
Het |
| Has1 |
A |
G |
17: 18,064,008 (GRCm39) |
Y544H |
probably benign |
Het |
| Hc |
A |
T |
2: 34,903,583 (GRCm39) |
Y1024N |
probably damaging |
Het |
| Hoxa13 |
CCG |
CCGCG |
6: 52,237,618 (GRCm39) |
|
probably null |
Het |
| Ift122 |
T |
A |
6: 115,882,863 (GRCm39) |
H659Q |
probably benign |
Het |
| Itga2 |
T |
C |
13: 114,990,435 (GRCm39) |
Q902R |
probably benign |
Het |
| Itgb2l |
T |
C |
16: 96,235,901 (GRCm39) |
K181E |
possibly damaging |
Het |
| Jak3 |
A |
T |
8: 72,135,041 (GRCm39) |
H558L |
probably damaging |
Het |
| Kcnh8 |
A |
G |
17: 53,032,886 (GRCm39) |
T58A |
probably benign |
Het |
| Klhl6 |
GT |
G |
16: 19,775,716 (GRCm39) |
279 |
probably null |
Het |
| Krt33a |
C |
T |
11: 99,903,155 (GRCm39) |
|
probably benign |
Het |
| Magi2 |
A |
T |
5: 20,866,357 (GRCm39) |
|
probably benign |
Het |
| Map4 |
G |
A |
9: 109,868,918 (GRCm39) |
|
probably benign |
Het |
| Map4k4 |
T |
A |
1: 40,045,982 (GRCm39) |
S754T |
probably damaging |
Het |
| Mapk8ip3 |
A |
G |
17: 25,133,424 (GRCm39) |
|
probably benign |
Het |
| Mib1 |
A |
G |
18: 10,804,773 (GRCm39) |
S918G |
probably benign |
Het |
| Mipol1 |
T |
A |
12: 57,503,963 (GRCm39) |
V377D |
probably damaging |
Het |
| Mlh1 |
T |
C |
9: 111,070,624 (GRCm39) |
T364A |
probably benign |
Het |
| Mta1 |
C |
T |
12: 113,094,941 (GRCm39) |
Q400* |
probably null |
Het |
| Mthfd1l |
C |
G |
10: 4,040,006 (GRCm39) |
R806G |
probably benign |
Het |
| Myom1 |
A |
G |
17: 71,391,301 (GRCm39) |
K937E |
probably damaging |
Het |
| Naxd |
T |
C |
8: 11,560,224 (GRCm39) |
|
probably benign |
Het |
| Negr1 |
G |
T |
3: 156,721,904 (GRCm39) |
K159N |
probably damaging |
Het |
| Nwd2 |
G |
T |
5: 63,963,686 (GRCm39) |
W1090L |
probably damaging |
Het |
| Or1e1f |
T |
C |
11: 73,855,706 (GRCm39) |
S91P |
probably benign |
Het |
| Or2j3 |
A |
G |
17: 38,615,549 (GRCm39) |
S268P |
probably damaging |
Het |
| Or51v14 |
C |
T |
7: 103,261,204 (GRCm39) |
A119T |
probably benign |
Het |
| Or52r1c |
T |
C |
7: 102,734,797 (GRCm39) |
I19T |
probably damaging |
Het |
| Or5d41 |
A |
T |
2: 88,054,499 (GRCm39) |
Y292* |
probably null |
Het |
| Pcsk6 |
G |
A |
7: 65,576,997 (GRCm39) |
S58N |
probably benign |
Het |
| Pdzrn3 |
G |
A |
6: 101,127,531 (GRCm39) |
T1045I |
possibly damaging |
Het |
| Pitrm1 |
T |
C |
13: 6,618,750 (GRCm39) |
L641P |
probably damaging |
Het |
| Pkd1l1 |
G |
T |
11: 8,879,430 (GRCm39) |
H474N |
probably damaging |
Het |
| Pltp |
A |
G |
2: 164,694,381 (GRCm39) |
|
probably benign |
Het |
| Qtrt1 |
C |
T |
9: 21,330,844 (GRCm39) |
T324M |
probably benign |
Het |
| Racgap1 |
A |
T |
15: 99,537,713 (GRCm39) |
|
probably benign |
Het |
| Rhbg |
A |
G |
3: 88,161,805 (GRCm39) |
V50A |
probably benign |
Het |
| Rnf135 |
G |
A |
11: 80,074,776 (GRCm39) |
V12M |
probably damaging |
Het |
| Rnf7l |
G |
T |
10: 63,257,381 (GRCm39) |
C46* |
probably null |
Het |
| Rufy2 |
T |
C |
10: 62,828,949 (GRCm39) |
V117A |
probably damaging |
Het |
| Safb |
A |
G |
17: 56,912,630 (GRCm39) |
M866V |
probably benign |
Het |
| Slc35c2 |
G |
T |
2: 165,122,735 (GRCm39) |
T183K |
probably damaging |
Het |
| Slc39a7 |
A |
G |
17: 34,248,512 (GRCm39) |
L377P |
probably damaging |
Het |
| Slit1 |
G |
A |
19: 41,596,750 (GRCm39) |
|
probably benign |
Het |
| Spaca9 |
G |
A |
2: 28,583,022 (GRCm39) |
H133Y |
probably damaging |
Het |
| Spout1 |
A |
G |
2: 30,064,983 (GRCm39) |
F339S |
probably benign |
Het |
| St6gal2 |
A |
G |
17: 55,789,015 (GRCm39) |
I16M |
probably damaging |
Het |
| Stat2 |
T |
C |
10: 128,112,378 (GRCm39) |
M6T |
probably benign |
Het |
| Swt1 |
T |
A |
1: 151,287,021 (GRCm39) |
H157L |
probably benign |
Het |
| Syne2 |
A |
G |
12: 76,085,714 (GRCm39) |
N147D |
possibly damaging |
Het |
| Tmem222 |
A |
T |
4: 133,004,902 (GRCm39) |
M45K |
possibly damaging |
Het |
| Tmem30a |
T |
A |
9: 79,684,567 (GRCm39) |
H95L |
probably damaging |
Het |
| Tns3 |
A |
C |
11: 8,497,262 (GRCm39) |
|
probably benign |
Het |
| Trpm3 |
A |
G |
19: 22,676,142 (GRCm39) |
I103V |
probably benign |
Het |
| Ube2n |
T |
C |
10: 95,377,206 (GRCm39) |
F57S |
probably benign |
Het |
| Vil1 |
T |
C |
1: 74,460,499 (GRCm39) |
S219P |
possibly damaging |
Het |
| Wdfy4 |
A |
G |
14: 32,862,695 (GRCm39) |
|
probably benign |
Het |
| Wdr7 |
T |
C |
18: 63,924,914 (GRCm39) |
S966P |
probably benign |
Het |
| Wnt8a |
A |
G |
18: 34,677,900 (GRCm39) |
N103D |
probably damaging |
Het |
| Zfp523 |
G |
A |
17: 28,419,419 (GRCm39) |
E186K |
possibly damaging |
Het |
| Zfp791 |
A |
T |
8: 85,836,609 (GRCm39) |
D418E |
probably benign |
Het |
| Zscan20 |
A |
G |
4: 128,485,682 (GRCm39) |
V192A |
probably benign |
Het |
|
| Other mutations in Myh13 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00497:Myh13
|
APN |
11 |
67,233,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00808:Myh13
|
APN |
11 |
67,225,830 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00822:Myh13
|
APN |
11 |
67,252,154 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL00823:Myh13
|
APN |
11 |
67,246,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00945:Myh13
|
APN |
11 |
67,238,832 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL01414:Myh13
|
APN |
11 |
67,233,298 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01482:Myh13
|
APN |
11 |
67,242,894 (GRCm39) |
missense |
probably benign |
|
|
IGL01523:Myh13
|
APN |
11 |
67,238,769 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01723:Myh13
|
APN |
11 |
67,260,045 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01997:Myh13
|
APN |
11 |
67,257,992 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02369:Myh13
|
APN |
11 |
67,251,100 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02478:Myh13
|
APN |
11 |
67,260,204 (GRCm39) |
missense |
probably benign |
|
|
IGL02663:Myh13
|
APN |
11 |
67,245,753 (GRCm39) |
nonsense |
probably null |
|
|
IGL02851:Myh13
|
APN |
11 |
67,239,742 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02863:Myh13
|
APN |
11 |
67,223,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02929:Myh13
|
APN |
11 |
67,257,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02979:Myh13
|
APN |
11 |
67,225,788 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL03065:Myh13
|
APN |
11 |
67,235,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03214:Myh13
|
APN |
11 |
67,244,411 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL03223:Myh13
|
APN |
11 |
67,241,068 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL03231:Myh13
|
APN |
11 |
67,242,817 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03407:Myh13
|
APN |
11 |
67,242,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Myh13
|
UTSW |
11 |
67,242,777 (GRCm39) |
splice site |
probably benign |
|
|
P0042:Myh13
|
UTSW |
11 |
67,225,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0047:Myh13
|
UTSW |
11 |
67,258,063 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0047:Myh13
|
UTSW |
11 |
67,258,063 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0379:Myh13
|
UTSW |
11 |
67,260,121 (GRCm39) |
unclassified |
probably benign |
|
|
R0584:Myh13
|
UTSW |
11 |
67,251,200 (GRCm39) |
nonsense |
probably null |
|
|
R0595:Myh13
|
UTSW |
11 |
67,235,672 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0621:Myh13
|
UTSW |
11 |
67,232,058 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Myh13
|
UTSW |
11 |
67,240,436 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0893:Myh13
|
UTSW |
11 |
67,225,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0964:Myh13
|
UTSW |
11 |
67,235,828 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0973:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0974:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1028:Myh13
|
UTSW |
11 |
67,247,007 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1112:Myh13
|
UTSW |
11 |
67,245,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1283:Myh13
|
UTSW |
11 |
67,261,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1288:Myh13
|
UTSW |
11 |
67,244,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1386:Myh13
|
UTSW |
11 |
67,261,776 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1457:Myh13
|
UTSW |
11 |
67,221,872 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1503:Myh13
|
UTSW |
11 |
67,244,500 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1574:Myh13
|
UTSW |
11 |
67,253,407 (GRCm39) |
unclassified |
probably benign |
|
|
R1673:Myh13
|
UTSW |
11 |
67,242,945 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1693:Myh13
|
UTSW |
11 |
67,232,310 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1763:Myh13
|
UTSW |
11 |
67,225,402 (GRCm39) |
missense |
probably benign |
|
|
R2029:Myh13
|
UTSW |
11 |
67,252,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2030:Myh13
|
UTSW |
11 |
67,241,064 (GRCm39) |
missense |
probably benign |
|
|
R2247:Myh13
|
UTSW |
11 |
67,225,384 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2393:Myh13
|
UTSW |
11 |
67,231,184 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2395:Myh13
|
UTSW |
11 |
67,255,748 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2884:Myh13
|
UTSW |
11 |
67,228,469 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3696:Myh13
|
UTSW |
11 |
67,235,870 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R3786:Myh13
|
UTSW |
11 |
67,218,014 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Myh13
|
UTSW |
11 |
67,249,020 (GRCm39) |
missense |
probably benign |
0.26 |
|
R3918:Myh13
|
UTSW |
11 |
67,220,064 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4061:Myh13
|
UTSW |
11 |
67,221,715 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4160:Myh13
|
UTSW |
11 |
67,255,636 (GRCm39) |
intron |
probably benign |
|
|
R4183:Myh13
|
UTSW |
11 |
67,240,436 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4392:Myh13
|
UTSW |
11 |
67,235,707 (GRCm39) |
splice site |
probably null |
|
|
R4639:Myh13
|
UTSW |
11 |
67,232,377 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4670:Myh13
|
UTSW |
11 |
67,255,564 (GRCm39) |
nonsense |
probably null |
|
|
R4783:Myh13
|
UTSW |
11 |
67,232,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4877:Myh13
|
UTSW |
11 |
67,228,477 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5250:Myh13
|
UTSW |
11 |
67,218,085 (GRCm39) |
nonsense |
probably null |
|
|
R5278:Myh13
|
UTSW |
11 |
67,225,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5371:Myh13
|
UTSW |
11 |
67,235,616 (GRCm39) |
splice site |
probably null |
|
|
R5479:Myh13
|
UTSW |
11 |
67,239,648 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5510:Myh13
|
UTSW |
11 |
67,228,549 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5690:Myh13
|
UTSW |
11 |
67,220,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5797:Myh13
|
UTSW |
11 |
67,225,828 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5823:Myh13
|
UTSW |
11 |
67,251,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Myh13
|
UTSW |
11 |
67,244,484 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6041:Myh13
|
UTSW |
11 |
67,255,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Myh13
|
UTSW |
11 |
67,245,588 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6244:Myh13
|
UTSW |
11 |
67,253,327 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6454:Myh13
|
UTSW |
11 |
67,241,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6617:Myh13
|
UTSW |
11 |
67,252,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6707:Myh13
|
UTSW |
11 |
67,241,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6747:Myh13
|
UTSW |
11 |
67,241,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6823:Myh13
|
UTSW |
11 |
67,246,984 (GRCm39) |
missense |
probably benign |
|
|
R6911:Myh13
|
UTSW |
11 |
67,245,753 (GRCm39) |
nonsense |
probably null |
|
|
R6997:Myh13
|
UTSW |
11 |
67,217,980 (GRCm39) |
nonsense |
probably null |
|
|
R7033:Myh13
|
UTSW |
11 |
67,260,142 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7145:Myh13
|
UTSW |
11 |
67,245,566 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7232:Myh13
|
UTSW |
11 |
67,239,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7428:Myh13
|
UTSW |
11 |
67,223,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7448:Myh13
|
UTSW |
11 |
67,255,286 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7474:Myh13
|
UTSW |
11 |
67,258,537 (GRCm39) |
missense |
|
|
|
R7474:Myh13
|
UTSW |
11 |
67,217,990 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7766:Myh13
|
UTSW |
11 |
67,249,155 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7809:Myh13
|
UTSW |
11 |
67,241,167 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7813:Myh13
|
UTSW |
11 |
67,218,056 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7953:Myh13
|
UTSW |
11 |
67,231,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8085:Myh13
|
UTSW |
11 |
67,225,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8397:Myh13
|
UTSW |
11 |
67,241,113 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8434:Myh13
|
UTSW |
11 |
67,254,011 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8490:Myh13
|
UTSW |
11 |
67,255,351 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8676:Myh13
|
UTSW |
11 |
67,233,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8681:Myh13
|
UTSW |
11 |
67,242,960 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8777:Myh13
|
UTSW |
11 |
67,252,161 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8777-TAIL:Myh13
|
UTSW |
11 |
67,252,161 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8965:Myh13
|
UTSW |
11 |
67,255,432 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9088:Myh13
|
UTSW |
11 |
67,242,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9151:Myh13
|
UTSW |
11 |
67,252,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Myh13
|
UTSW |
11 |
67,253,318 (GRCm39) |
missense |
probably benign |
|
|
R9182:Myh13
|
UTSW |
11 |
67,228,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Myh13
|
UTSW |
11 |
67,254,109 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9393:Myh13
|
UTSW |
11 |
67,242,894 (GRCm39) |
missense |
probably benign |
|
|
R9446:Myh13
|
UTSW |
11 |
67,255,325 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9474:Myh13
|
UTSW |
11 |
67,255,712 (GRCm39) |
missense |
|
|
|
R9690:Myh13
|
UTSW |
11 |
67,249,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9761:Myh13
|
UTSW |
11 |
67,251,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9778:Myh13
|
UTSW |
11 |
67,249,016 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Myh13
|
UTSW |
11 |
67,220,121 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Myh13
|
UTSW |
11 |
67,255,417 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Myh13
|
UTSW |
11 |
67,241,278 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCAGGTCAGAGAAGAGCCATTTCC -3'
(R):5'- TGCAAGACCAGGCTGCTCAAGTTG -3'
Sequencing Primer
(F):5'- AGAGCCATTTCCTCTGAAGG -3'
(R):5'- TTGACTGGAAGAAGAATGACCC -3'
|
| Posted On |
2013-05-29 |
Incidental Mutation