Incidental Mutation 'R0544:Atrn'
| ID |
44656 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atrn
|
| Ensembl Gene |
ENSMUSG00000027312 |
| Gene Name |
attractin |
| Synonyms |
Mgca |
| MMRRC Submission |
038736-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0544 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
130748415-130872253 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 130828746 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Aspartic acid
at position 1097
(G1097D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028781
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028781]
|
| AlphaFold |
Q9WU60 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000028781
AA Change: G1097D
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000028781
Gene: ENSMUSG00000027312
AA Change: G1097D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
9 |
N/A |
INTRINSIC |
|
low complexity region
|
51 |
97 |
N/A |
INTRINSIC |
|
EGF
|
99 |
129 |
9.85e-5 |
SMART |
|
CUB
|
131 |
247 |
7.85e-18 |
SMART |
|
EGF
|
248 |
282 |
1.47e1 |
SMART |
|
Pfam:Kelch_1
|
339 |
382 |
1.1e-7 |
PFAM |
|
Pfam:Kelch_5
|
389 |
434 |
2.5e-7 |
PFAM |
|
Pfam:Kelch_6
|
390 |
439 |
3.3e-8 |
PFAM |
|
Pfam:Kelch_1
|
553 |
606 |
8.4e-8 |
PFAM |
|
PSI
|
646 |
693 |
7.41e-7 |
SMART |
|
PSI
|
702 |
747 |
8.64e-8 |
SMART |
|
PSI
|
754 |
799 |
2.11e-2 |
SMART |
|
CLECT
|
787 |
918 |
6.14e-20 |
SMART |
|
PSI
|
931 |
982 |
1.11e-5 |
SMART |
|
PSI
|
985 |
1060 |
1.2e-6 |
SMART |
|
EGF_Lam
|
1062 |
1105 |
1.97e-4 |
SMART |
|
EGF_like
|
1108 |
1154 |
3.9e0 |
SMART |
|
transmembrane domain
|
1278 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1310 |
1322 |
N/A |
INTRINSIC |
|
low complexity region
|
1373 |
1385 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000121009
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132557
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134964
|
| Meta Mutation Damage Score |
0.8357 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
98% (97/99) |
| MGI Phenotype |
FUNCTION: This gene encodes a widely expressed transmembrane glycoprotein that plays important roles in diverse physiological processes such as regulation of hair pigmentation, monocyte-T cell interaction and control of energy homeostasis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the mahogany mouse phenotype of dark brown or black coat on a normally agouti background. Mice with loss-of-function mutations in this gene exhibit black coat color, tremor, adiposity, higher basal metabolic rate, juvenile-onset hypomyelination and age-dependent spongiform neurodegeneration of the central nervous system. [provided by RefSeq, Jul 2016]
PHENOTYPE: Some mutant homozygotes exhibit decreases in phaeomelanin synthesis, body weight, and adiposity; increases in locomotion, and abnormal myelination and vacuolation of the central nervous system resulting in tremors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9930012K11Rik |
A |
T |
14: 70,394,763 (GRCm39) |
F130L |
probably benign |
Het |
| Aatf |
C |
T |
11: 84,313,831 (GRCm39) |
R511Q |
probably benign |
Het |
| Acot12 |
A |
T |
13: 91,932,775 (GRCm39) |
D516V |
probably benign |
Het |
| Adgrb2 |
T |
C |
4: 129,911,335 (GRCm39) |
V1207A |
probably damaging |
Het |
| Akap9 |
A |
G |
5: 4,119,185 (GRCm39) |
D3564G |
probably benign |
Het |
| Arl8b |
C |
T |
6: 108,760,189 (GRCm39) |
|
probably benign |
Het |
| Atf6b |
T |
C |
17: 34,867,273 (GRCm39) |
|
probably null |
Het |
| Btbd6 |
A |
G |
12: 112,940,702 (GRCm39) |
E61G |
probably damaging |
Het |
| Car15 |
A |
G |
16: 17,653,680 (GRCm39) |
|
probably benign |
Het |
| Car5b |
G |
A |
X: 162,762,297 (GRCm39) |
R282C |
probably damaging |
Het |
| Carmil2 |
C |
T |
8: 106,417,867 (GRCm39) |
A654V |
probably damaging |
Het |
| Ccdc88b |
A |
G |
19: 6,834,634 (GRCm39) |
L124P |
probably damaging |
Het |
| Ccnd1 |
A |
G |
7: 144,491,023 (GRCm39) |
|
probably benign |
Het |
| Cenph |
A |
G |
13: 100,909,249 (GRCm39) |
S53P |
probably damaging |
Het |
| Chrm3 |
T |
A |
13: 9,927,615 (GRCm39) |
I474F |
probably damaging |
Het |
| Cln8 |
T |
A |
8: 14,946,769 (GRCm39) |
V261E |
probably benign |
Het |
| Coa6 |
A |
G |
8: 127,149,499 (GRCm39) |
D25G |
probably benign |
Het |
| Col4a1 |
T |
G |
8: 11,276,487 (GRCm39) |
|
probably benign |
Het |
| Cpxm1 |
T |
C |
2: 130,235,055 (GRCm39) |
H588R |
probably damaging |
Het |
| Cul7 |
T |
C |
17: 46,974,470 (GRCm39) |
L1516P |
possibly damaging |
Het |
| Dcdc5 |
A |
G |
2: 106,181,909 (GRCm39) |
|
noncoding transcript |
Het |
| Ddx5 |
T |
C |
11: 106,673,288 (GRCm39) |
|
probably benign |
Het |
| Dhx16 |
C |
A |
17: 36,192,551 (GRCm39) |
P161Q |
probably benign |
Het |
| Dpy19l1 |
A |
T |
9: 24,396,406 (GRCm39) |
|
probably benign |
Het |
| Fastkd5 |
A |
G |
2: 130,457,216 (GRCm39) |
V458A |
probably damaging |
Het |
| Fhit |
A |
G |
14: 9,870,172 (GRCm38) |
V99A |
probably damaging |
Het |
| Fndc3a |
A |
T |
14: 72,795,062 (GRCm39) |
|
probably benign |
Het |
| Foxd4 |
A |
T |
19: 24,877,182 (GRCm39) |
S339R |
possibly damaging |
Het |
| Gm10842 |
T |
A |
11: 105,037,880 (GRCm39) |
D54E |
unknown |
Het |
| Gns |
T |
A |
10: 121,212,172 (GRCm39) |
Y94* |
probably null |
Het |
| Gp2 |
A |
G |
7: 119,053,719 (GRCm39) |
W81R |
probably benign |
Het |
| Hdac5 |
T |
G |
11: 102,086,922 (GRCm39) |
Q46P |
probably damaging |
Het |
| Homer2 |
A |
C |
7: 81,299,426 (GRCm39) |
V13G |
probably damaging |
Het |
| Irs3 |
A |
G |
5: 137,642,101 (GRCm39) |
S446P |
probably benign |
Het |
| Ism2 |
G |
T |
12: 87,332,113 (GRCm39) |
D141E |
probably damaging |
Het |
| Jak1 |
T |
A |
4: 101,048,822 (GRCm39) |
M19L |
probably benign |
Het |
| Kcnd3 |
C |
A |
3: 105,566,075 (GRCm39) |
R419S |
probably damaging |
Het |
| Lamb1 |
T |
C |
12: 31,332,694 (GRCm39) |
F272S |
probably damaging |
Het |
| Ldlrad2 |
T |
G |
4: 137,299,579 (GRCm39) |
T82P |
possibly damaging |
Het |
| Lrp2 |
T |
C |
2: 69,322,275 (GRCm39) |
K1885E |
probably benign |
Het |
| Mbd5 |
T |
C |
2: 49,147,221 (GRCm39) |
V477A |
possibly damaging |
Het |
| Mrps33 |
A |
T |
6: 39,782,488 (GRCm39) |
M11K |
possibly damaging |
Het |
| Mylk |
G |
C |
16: 34,699,845 (GRCm39) |
E403Q |
possibly damaging |
Het |
| Myom2 |
T |
A |
8: 15,119,796 (GRCm39) |
V184E |
probably damaging |
Het |
| Ncor1 |
C |
A |
11: 62,224,602 (GRCm39) |
G1210V |
probably damaging |
Het |
| Ncor1 |
C |
T |
11: 62,224,603 (GRCm39) |
G1210R |
probably damaging |
Het |
| Nlrp4a |
A |
G |
7: 26,156,555 (GRCm39) |
D760G |
probably benign |
Het |
| Noc4l |
A |
G |
5: 110,798,989 (GRCm39) |
V231A |
possibly damaging |
Het |
| Or2at1 |
T |
C |
7: 99,416,867 (GRCm39) |
I166T |
probably benign |
Het |
| Or4c112 |
T |
C |
2: 88,854,170 (GRCm39) |
Y59C |
probably damaging |
Het |
| Or4f14 |
A |
T |
2: 111,742,905 (GRCm39) |
Y123* |
probably null |
Het |
| Or4n4b |
A |
T |
14: 50,536,139 (GRCm39) |
V209E |
probably benign |
Het |
| Or52ab7 |
T |
A |
7: 102,977,858 (GRCm39) |
I55N |
probably damaging |
Het |
| Or5b98 |
A |
G |
19: 12,931,066 (GRCm39) |
T38A |
possibly damaging |
Het |
| Or5h25 |
T |
A |
16: 58,930,588 (GRCm39) |
K128N |
probably benign |
Het |
| Or8k23 |
T |
C |
2: 86,186,007 (GRCm39) |
T240A |
probably damaging |
Het |
| Padi4 |
GCTGCGTACCTCCAC |
GC |
4: 140,475,760 (GRCm39) |
|
probably benign |
Het |
| Patj |
T |
A |
4: 98,457,347 (GRCm39) |
M1283K |
probably damaging |
Het |
| Pkd1 |
C |
T |
17: 24,804,657 (GRCm39) |
T790I |
probably damaging |
Het |
| Plod3 |
C |
A |
5: 137,020,465 (GRCm39) |
T526K |
probably benign |
Het |
| Plxnb2 |
C |
A |
15: 89,042,816 (GRCm39) |
|
probably benign |
Het |
| Polr1g |
G |
T |
7: 19,093,066 (GRCm39) |
P38Q |
probably damaging |
Het |
| Pramel1 |
T |
A |
4: 143,124,175 (GRCm39) |
D283E |
possibly damaging |
Het |
| Prpf40a |
T |
C |
2: 53,031,663 (GRCm39) |
|
probably benign |
Het |
| Psg23 |
A |
T |
7: 18,348,607 (GRCm39) |
Y67N |
probably damaging |
Het |
| Rftn1 |
T |
A |
17: 50,301,289 (GRCm39) |
Q242L |
possibly damaging |
Het |
| Rp1l1 |
A |
T |
14: 64,269,515 (GRCm39) |
E1700D |
probably benign |
Het |
| Scube3 |
T |
C |
17: 28,383,127 (GRCm39) |
F435S |
probably damaging |
Het |
| Sdk2 |
T |
C |
11: 113,671,836 (GRCm39) |
Y2104C |
probably damaging |
Het |
| Septin11 |
A |
G |
5: 93,313,227 (GRCm39) |
E358G |
possibly damaging |
Het |
| Sh3bp1 |
T |
C |
15: 78,789,975 (GRCm39) |
L246P |
probably damaging |
Het |
| Sis |
T |
C |
3: 72,858,975 (GRCm39) |
Y352C |
probably damaging |
Het |
| Skint1 |
T |
C |
4: 111,878,562 (GRCm39) |
S165P |
probably damaging |
Het |
| Skint10 |
C |
T |
4: 112,586,008 (GRCm39) |
|
probably benign |
Het |
| Slc1a2 |
A |
T |
2: 102,586,417 (GRCm39) |
R340S |
probably damaging |
Het |
| Slc26a3 |
C |
A |
12: 31,497,739 (GRCm39) |
Q48K |
probably benign |
Het |
| Slc5a2 |
A |
T |
7: 127,869,171 (GRCm39) |
Y317F |
probably damaging |
Het |
| Sorbs3 |
T |
A |
14: 70,431,375 (GRCm39) |
T262S |
probably benign |
Het |
| Tas2r118 |
G |
T |
6: 23,969,400 (GRCm39) |
S220R |
probably damaging |
Het |
| Terf2ip |
C |
A |
8: 112,741,974 (GRCm39) |
Q223K |
possibly damaging |
Het |
| Tespa1 |
A |
G |
10: 130,196,680 (GRCm39) |
Q206R |
probably damaging |
Het |
| Tex10 |
T |
C |
4: 48,462,766 (GRCm39) |
|
probably null |
Het |
| Tle1 |
T |
A |
4: 72,043,227 (GRCm39) |
K547N |
probably damaging |
Het |
| Tmem131l |
T |
A |
3: 83,805,853 (GRCm39) |
Q1530L |
probably damaging |
Het |
| Tomm20l |
A |
G |
12: 71,169,851 (GRCm39) |
E145G |
possibly damaging |
Het |
| Tra2a |
C |
T |
6: 49,227,885 (GRCm39) |
|
probably benign |
Het |
| Trim32 |
G |
A |
4: 65,531,491 (GRCm39) |
R16Q |
probably damaging |
Het |
| Trim37 |
T |
A |
11: 87,036,328 (GRCm39) |
Y121* |
probably null |
Het |
| Tube1 |
C |
T |
10: 39,016,941 (GRCm39) |
|
probably null |
Het |
| Usp6nl |
T |
A |
2: 6,425,820 (GRCm39) |
V187D |
probably damaging |
Het |
| Vmn1r13 |
T |
C |
6: 57,187,248 (GRCm39) |
F136L |
probably benign |
Het |
| Vmn1r201 |
A |
T |
13: 22,659,316 (GRCm39) |
I177F |
probably benign |
Het |
| Vmn1r203 |
A |
T |
13: 22,708,443 (GRCm39) |
T75S |
possibly damaging |
Het |
| Vmn1r225 |
C |
T |
17: 20,722,718 (GRCm39) |
S53L |
probably benign |
Het |
| Xab2 |
A |
T |
8: 3,660,994 (GRCm39) |
W707R |
probably damaging |
Het |
| Zfp808 |
T |
C |
13: 62,317,248 (GRCm39) |
|
probably benign |
Het |
| Zng1 |
A |
G |
19: 24,926,575 (GRCm39) |
Y159H |
possibly damaging |
Het |
|
| Other mutations in Atrn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Atrn
|
APN |
2 |
130,799,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00571:Atrn
|
APN |
2 |
130,836,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01092:Atrn
|
APN |
2 |
130,789,556 (GRCm39) |
nonsense |
probably null |
|
|
IGL01572:Atrn
|
APN |
2 |
130,844,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01924:Atrn
|
APN |
2 |
130,777,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02116:Atrn
|
APN |
2 |
130,800,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02372:Atrn
|
APN |
2 |
130,844,674 (GRCm39) |
splice site |
probably benign |
|
|
IGL02390:Atrn
|
APN |
2 |
130,862,897 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02548:Atrn
|
APN |
2 |
130,814,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02749:Atrn
|
APN |
2 |
130,789,654 (GRCm39) |
splice site |
probably benign |
|
|
IGL02749:Atrn
|
APN |
2 |
130,812,064 (GRCm39) |
nonsense |
probably null |
|
|
BB010:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB020:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0026:Atrn
|
UTSW |
2 |
130,799,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0403:Atrn
|
UTSW |
2 |
130,748,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0479:Atrn
|
UTSW |
2 |
130,841,085 (GRCm39) |
nonsense |
probably null |
|
|
R0570:Atrn
|
UTSW |
2 |
130,822,054 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0606:Atrn
|
UTSW |
2 |
130,748,776 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0617:Atrn
|
UTSW |
2 |
130,837,005 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0658:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1108:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1112:Atrn
|
UTSW |
2 |
130,841,081 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1219:Atrn
|
UTSW |
2 |
130,862,927 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1422:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1524:Atrn
|
UTSW |
2 |
130,799,000 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1653:Atrn
|
UTSW |
2 |
130,777,544 (GRCm39) |
missense |
probably benign |
|
|
R1795:Atrn
|
UTSW |
2 |
130,814,208 (GRCm39) |
missense |
probably benign |
|
|
R1807:Atrn
|
UTSW |
2 |
130,824,692 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1920:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1921:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1935:Atrn
|
UTSW |
2 |
130,799,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1982:Atrn
|
UTSW |
2 |
130,812,142 (GRCm39) |
missense |
probably benign |
|
|
R2000:Atrn
|
UTSW |
2 |
130,777,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Atrn
|
UTSW |
2 |
130,799,916 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2336:Atrn
|
UTSW |
2 |
130,799,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2679:Atrn
|
UTSW |
2 |
130,803,595 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3426:Atrn
|
UTSW |
2 |
130,862,876 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3909:Atrn
|
UTSW |
2 |
130,836,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4077:Atrn
|
UTSW |
2 |
130,806,850 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4162:Atrn
|
UTSW |
2 |
130,836,148 (GRCm39) |
splice site |
probably benign |
|
|
R4195:Atrn
|
UTSW |
2 |
130,775,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4364:Atrn
|
UTSW |
2 |
130,812,128 (GRCm39) |
missense |
probably benign |
0.39 |
|
R4465:Atrn
|
UTSW |
2 |
130,802,388 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4510:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4511:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4527:Atrn
|
UTSW |
2 |
130,815,424 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4586:Atrn
|
UTSW |
2 |
130,823,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4592:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R4658:Atrn
|
UTSW |
2 |
130,775,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4735:Atrn
|
UTSW |
2 |
130,862,910 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4960:Atrn
|
UTSW |
2 |
130,836,967 (GRCm39) |
nonsense |
probably null |
|
|
R4999:Atrn
|
UTSW |
2 |
130,817,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5066:Atrn
|
UTSW |
2 |
130,836,113 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5080:Atrn
|
UTSW |
2 |
130,812,044 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5141:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R5256:Atrn
|
UTSW |
2 |
130,787,939 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5494:Atrn
|
UTSW |
2 |
130,864,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5678:Atrn
|
UTSW |
2 |
130,811,936 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5752:Atrn
|
UTSW |
2 |
130,748,464 (GRCm39) |
unclassified |
probably benign |
|
|
R5931:Atrn
|
UTSW |
2 |
130,775,356 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6023:Atrn
|
UTSW |
2 |
130,862,900 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6176:Atrn
|
UTSW |
2 |
130,788,011 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6377:Atrn
|
UTSW |
2 |
130,821,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6433:Atrn
|
UTSW |
2 |
130,864,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7226:Atrn
|
UTSW |
2 |
130,828,664 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7402:Atrn
|
UTSW |
2 |
130,789,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7541:Atrn
|
UTSW |
2 |
130,803,491 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7587:Atrn
|
UTSW |
2 |
130,822,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7910:Atrn
|
UTSW |
2 |
130,806,807 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7913:Atrn
|
UTSW |
2 |
130,812,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7933:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8044:Atrn
|
UTSW |
2 |
130,777,449 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8079:Atrn
|
UTSW |
2 |
130,855,561 (GRCm39) |
missense |
probably null |
1.00 |
|
R8093:Atrn
|
UTSW |
2 |
130,817,908 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8203:Atrn
|
UTSW |
2 |
130,802,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8234:Atrn
|
UTSW |
2 |
130,864,920 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8462:Atrn
|
UTSW |
2 |
130,777,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,846,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,748,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8831:Atrn
|
UTSW |
2 |
130,748,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8937:Atrn
|
UTSW |
2 |
130,841,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9161:Atrn
|
UTSW |
2 |
130,777,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9722:Atrn
|
UTSW |
2 |
130,803,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9786:Atrn
|
UTSW |
2 |
130,786,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF009:Atrn
|
UTSW |
2 |
130,748,842 (GRCm39) |
missense |
probably benign |
0.12 |
|
X0024:Atrn
|
UTSW |
2 |
130,800,059 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Atrn
|
UTSW |
2 |
130,815,319 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Atrn
|
UTSW |
2 |
130,788,113 (GRCm39) |
missense |
probably benign |
0.27 |
|
Z1177:Atrn
|
UTSW |
2 |
130,787,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- aaATCCACACCCAATACTTTGTCCTCTC -3'
(R):5'- ccacatttctagccccTCAGTTAAACTT -3'
Sequencing Primer
(F):5'- aggctgacctgaaacttctg -3'
(R):5'- CCAAGAGGCCTTTTCCCTTT -3'
|
| Posted On |
2013-06-11 |
Incidental Mutation