Incidental Mutation 'R0544:Rp1l1'
| ID |
44715 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rp1l1
|
| Ensembl Gene |
ENSMUSG00000046049 |
| Gene Name |
retinitis pigmentosa 1 homolog like 1 |
| Synonyms |
Dcdc4, Rp1hl1 |
| MMRRC Submission |
038736-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.078)
|
| Stock # |
R0544 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
64229880-64270955 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 64269515 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 1700
(E1700D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000055449
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000058229]
|
| AlphaFold |
Q8CGM2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000058229
AA Change: E1700D
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000055449
Gene: ENSMUSG00000046049
AA Change: E1700D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
21 |
N/A |
INTRINSIC |
|
DCX
|
37 |
121 |
1.58e-13 |
SMART |
|
DCX
|
155 |
239 |
1e-15 |
SMART |
|
low complexity region
|
709 |
728 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
884 |
N/A |
INTRINSIC |
|
low complexity region
|
1159 |
1177 |
N/A |
INTRINSIC |
|
low complexity region
|
1228 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1612 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1642 |
1652 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000224314
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
98% (97/99) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the doublecortin family. This protein is a retinal-specific protein. It contains two N-terminal doublecortin domains, which can assemble and stabilize axonemal microtubules, but lacks the C-terminal repetitive regions including the 16aa repeat found in human RP1L1. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. [provided by RefSeq, Sep 2010]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit retinal photoreceptor abnormalities, including scattered outer segment disorganization, reduced electroretinogram amplitudes, and progressive retinal rod cell degeneration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9930012K11Rik |
A |
T |
14: 70,394,763 (GRCm39) |
F130L |
probably benign |
Het |
| Aatf |
C |
T |
11: 84,313,831 (GRCm39) |
R511Q |
probably benign |
Het |
| Acot12 |
A |
T |
13: 91,932,775 (GRCm39) |
D516V |
probably benign |
Het |
| Adgrb2 |
T |
C |
4: 129,911,335 (GRCm39) |
V1207A |
probably damaging |
Het |
| Akap9 |
A |
G |
5: 4,119,185 (GRCm39) |
D3564G |
probably benign |
Het |
| Arl8b |
C |
T |
6: 108,760,189 (GRCm39) |
|
probably benign |
Het |
| Atf6b |
T |
C |
17: 34,867,273 (GRCm39) |
|
probably null |
Het |
| Atrn |
G |
A |
2: 130,828,746 (GRCm39) |
G1097D |
probably damaging |
Het |
| Btbd6 |
A |
G |
12: 112,940,702 (GRCm39) |
E61G |
probably damaging |
Het |
| Car15 |
A |
G |
16: 17,653,680 (GRCm39) |
|
probably benign |
Het |
| Car5b |
G |
A |
X: 162,762,297 (GRCm39) |
R282C |
probably damaging |
Het |
| Carmil2 |
C |
T |
8: 106,417,867 (GRCm39) |
A654V |
probably damaging |
Het |
| Ccdc88b |
A |
G |
19: 6,834,634 (GRCm39) |
L124P |
probably damaging |
Het |
| Ccnd1 |
A |
G |
7: 144,491,023 (GRCm39) |
|
probably benign |
Het |
| Cenph |
A |
G |
13: 100,909,249 (GRCm39) |
S53P |
probably damaging |
Het |
| Chrm3 |
T |
A |
13: 9,927,615 (GRCm39) |
I474F |
probably damaging |
Het |
| Cln8 |
T |
A |
8: 14,946,769 (GRCm39) |
V261E |
probably benign |
Het |
| Coa6 |
A |
G |
8: 127,149,499 (GRCm39) |
D25G |
probably benign |
Het |
| Col4a1 |
T |
G |
8: 11,276,487 (GRCm39) |
|
probably benign |
Het |
| Cpxm1 |
T |
C |
2: 130,235,055 (GRCm39) |
H588R |
probably damaging |
Het |
| Cul7 |
T |
C |
17: 46,974,470 (GRCm39) |
L1516P |
possibly damaging |
Het |
| Dcdc5 |
A |
G |
2: 106,181,909 (GRCm39) |
|
noncoding transcript |
Het |
| Ddx5 |
T |
C |
11: 106,673,288 (GRCm39) |
|
probably benign |
Het |
| Dhx16 |
C |
A |
17: 36,192,551 (GRCm39) |
P161Q |
probably benign |
Het |
| Dpy19l1 |
A |
T |
9: 24,396,406 (GRCm39) |
|
probably benign |
Het |
| Fastkd5 |
A |
G |
2: 130,457,216 (GRCm39) |
V458A |
probably damaging |
Het |
| Fhit |
A |
G |
14: 9,870,172 (GRCm38) |
V99A |
probably damaging |
Het |
| Fndc3a |
A |
T |
14: 72,795,062 (GRCm39) |
|
probably benign |
Het |
| Foxd4 |
A |
T |
19: 24,877,182 (GRCm39) |
S339R |
possibly damaging |
Het |
| Gm10842 |
T |
A |
11: 105,037,880 (GRCm39) |
D54E |
unknown |
Het |
| Gns |
T |
A |
10: 121,212,172 (GRCm39) |
Y94* |
probably null |
Het |
| Gp2 |
A |
G |
7: 119,053,719 (GRCm39) |
W81R |
probably benign |
Het |
| Hdac5 |
T |
G |
11: 102,086,922 (GRCm39) |
Q46P |
probably damaging |
Het |
| Homer2 |
A |
C |
7: 81,299,426 (GRCm39) |
V13G |
probably damaging |
Het |
| Irs3 |
A |
G |
5: 137,642,101 (GRCm39) |
S446P |
probably benign |
Het |
| Ism2 |
G |
T |
12: 87,332,113 (GRCm39) |
D141E |
probably damaging |
Het |
| Jak1 |
T |
A |
4: 101,048,822 (GRCm39) |
M19L |
probably benign |
Het |
| Kcnd3 |
C |
A |
3: 105,566,075 (GRCm39) |
R419S |
probably damaging |
Het |
| Lamb1 |
T |
C |
12: 31,332,694 (GRCm39) |
F272S |
probably damaging |
Het |
| Ldlrad2 |
T |
G |
4: 137,299,579 (GRCm39) |
T82P |
possibly damaging |
Het |
| Lrp2 |
T |
C |
2: 69,322,275 (GRCm39) |
K1885E |
probably benign |
Het |
| Mbd5 |
T |
C |
2: 49,147,221 (GRCm39) |
V477A |
possibly damaging |
Het |
| Mrps33 |
A |
T |
6: 39,782,488 (GRCm39) |
M11K |
possibly damaging |
Het |
| Mylk |
G |
C |
16: 34,699,845 (GRCm39) |
E403Q |
possibly damaging |
Het |
| Myom2 |
T |
A |
8: 15,119,796 (GRCm39) |
V184E |
probably damaging |
Het |
| Ncor1 |
C |
A |
11: 62,224,602 (GRCm39) |
G1210V |
probably damaging |
Het |
| Ncor1 |
C |
T |
11: 62,224,603 (GRCm39) |
G1210R |
probably damaging |
Het |
| Nlrp4a |
A |
G |
7: 26,156,555 (GRCm39) |
D760G |
probably benign |
Het |
| Noc4l |
A |
G |
5: 110,798,989 (GRCm39) |
V231A |
possibly damaging |
Het |
| Or2at1 |
T |
C |
7: 99,416,867 (GRCm39) |
I166T |
probably benign |
Het |
| Or4c112 |
T |
C |
2: 88,854,170 (GRCm39) |
Y59C |
probably damaging |
Het |
| Or4f14 |
A |
T |
2: 111,742,905 (GRCm39) |
Y123* |
probably null |
Het |
| Or4n4b |
A |
T |
14: 50,536,139 (GRCm39) |
V209E |
probably benign |
Het |
| Or52ab7 |
T |
A |
7: 102,977,858 (GRCm39) |
I55N |
probably damaging |
Het |
| Or5b98 |
A |
G |
19: 12,931,066 (GRCm39) |
T38A |
possibly damaging |
Het |
| Or5h25 |
T |
A |
16: 58,930,588 (GRCm39) |
K128N |
probably benign |
Het |
| Or8k23 |
T |
C |
2: 86,186,007 (GRCm39) |
T240A |
probably damaging |
Het |
| Padi4 |
GCTGCGTACCTCCAC |
GC |
4: 140,475,760 (GRCm39) |
|
probably benign |
Het |
| Patj |
T |
A |
4: 98,457,347 (GRCm39) |
M1283K |
probably damaging |
Het |
| Pkd1 |
C |
T |
17: 24,804,657 (GRCm39) |
T790I |
probably damaging |
Het |
| Plod3 |
C |
A |
5: 137,020,465 (GRCm39) |
T526K |
probably benign |
Het |
| Plxnb2 |
C |
A |
15: 89,042,816 (GRCm39) |
|
probably benign |
Het |
| Polr1g |
G |
T |
7: 19,093,066 (GRCm39) |
P38Q |
probably damaging |
Het |
| Pramel1 |
T |
A |
4: 143,124,175 (GRCm39) |
D283E |
possibly damaging |
Het |
| Prpf40a |
T |
C |
2: 53,031,663 (GRCm39) |
|
probably benign |
Het |
| Psg23 |
A |
T |
7: 18,348,607 (GRCm39) |
Y67N |
probably damaging |
Het |
| Rftn1 |
T |
A |
17: 50,301,289 (GRCm39) |
Q242L |
possibly damaging |
Het |
| Scube3 |
T |
C |
17: 28,383,127 (GRCm39) |
F435S |
probably damaging |
Het |
| Sdk2 |
T |
C |
11: 113,671,836 (GRCm39) |
Y2104C |
probably damaging |
Het |
| Septin11 |
A |
G |
5: 93,313,227 (GRCm39) |
E358G |
possibly damaging |
Het |
| Sh3bp1 |
T |
C |
15: 78,789,975 (GRCm39) |
L246P |
probably damaging |
Het |
| Sis |
T |
C |
3: 72,858,975 (GRCm39) |
Y352C |
probably damaging |
Het |
| Skint1 |
T |
C |
4: 111,878,562 (GRCm39) |
S165P |
probably damaging |
Het |
| Skint10 |
C |
T |
4: 112,586,008 (GRCm39) |
|
probably benign |
Het |
| Slc1a2 |
A |
T |
2: 102,586,417 (GRCm39) |
R340S |
probably damaging |
Het |
| Slc26a3 |
C |
A |
12: 31,497,739 (GRCm39) |
Q48K |
probably benign |
Het |
| Slc5a2 |
A |
T |
7: 127,869,171 (GRCm39) |
Y317F |
probably damaging |
Het |
| Sorbs3 |
T |
A |
14: 70,431,375 (GRCm39) |
T262S |
probably benign |
Het |
| Tas2r118 |
G |
T |
6: 23,969,400 (GRCm39) |
S220R |
probably damaging |
Het |
| Terf2ip |
C |
A |
8: 112,741,974 (GRCm39) |
Q223K |
possibly damaging |
Het |
| Tespa1 |
A |
G |
10: 130,196,680 (GRCm39) |
Q206R |
probably damaging |
Het |
| Tex10 |
T |
C |
4: 48,462,766 (GRCm39) |
|
probably null |
Het |
| Tle1 |
T |
A |
4: 72,043,227 (GRCm39) |
K547N |
probably damaging |
Het |
| Tmem131l |
T |
A |
3: 83,805,853 (GRCm39) |
Q1530L |
probably damaging |
Het |
| Tomm20l |
A |
G |
12: 71,169,851 (GRCm39) |
E145G |
possibly damaging |
Het |
| Tra2a |
C |
T |
6: 49,227,885 (GRCm39) |
|
probably benign |
Het |
| Trim32 |
G |
A |
4: 65,531,491 (GRCm39) |
R16Q |
probably damaging |
Het |
| Trim37 |
T |
A |
11: 87,036,328 (GRCm39) |
Y121* |
probably null |
Het |
| Tube1 |
C |
T |
10: 39,016,941 (GRCm39) |
|
probably null |
Het |
| Usp6nl |
T |
A |
2: 6,425,820 (GRCm39) |
V187D |
probably damaging |
Het |
| Vmn1r13 |
T |
C |
6: 57,187,248 (GRCm39) |
F136L |
probably benign |
Het |
| Vmn1r201 |
A |
T |
13: 22,659,316 (GRCm39) |
I177F |
probably benign |
Het |
| Vmn1r203 |
A |
T |
13: 22,708,443 (GRCm39) |
T75S |
possibly damaging |
Het |
| Vmn1r225 |
C |
T |
17: 20,722,718 (GRCm39) |
S53L |
probably benign |
Het |
| Xab2 |
A |
T |
8: 3,660,994 (GRCm39) |
W707R |
probably damaging |
Het |
| Zfp808 |
T |
C |
13: 62,317,248 (GRCm39) |
|
probably benign |
Het |
| Zng1 |
A |
G |
19: 24,926,575 (GRCm39) |
Y159H |
possibly damaging |
Het |
|
| Other mutations in Rp1l1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00494:Rp1l1
|
APN |
14 |
64,266,174 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02063:Rp1l1
|
APN |
14 |
64,266,985 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02132:Rp1l1
|
APN |
14 |
64,266,259 (GRCm39) |
missense |
probably benign |
|
|
IGL02430:Rp1l1
|
APN |
14 |
64,266,735 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02977:Rp1l1
|
APN |
14 |
64,265,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03213:Rp1l1
|
APN |
14 |
64,265,864 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03346:Rp1l1
|
APN |
14 |
64,266,889 (GRCm39) |
missense |
probably benign |
|
|
R0085:Rp1l1
|
UTSW |
14 |
64,259,744 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0347:Rp1l1
|
UTSW |
14 |
64,268,253 (GRCm39) |
nonsense |
probably null |
|
|
R0362:Rp1l1
|
UTSW |
14 |
64,268,515 (GRCm39) |
nonsense |
probably null |
|
|
R0369:Rp1l1
|
UTSW |
14 |
64,266,837 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0538:Rp1l1
|
UTSW |
14 |
64,259,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0780:Rp1l1
|
UTSW |
14 |
64,267,800 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0944:Rp1l1
|
UTSW |
14 |
64,269,681 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1051:Rp1l1
|
UTSW |
14 |
64,269,984 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1126:Rp1l1
|
UTSW |
14 |
64,267,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1450:Rp1l1
|
UTSW |
14 |
64,265,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1483:Rp1l1
|
UTSW |
14 |
64,266,496 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R1508:Rp1l1
|
UTSW |
14 |
64,268,341 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1553:Rp1l1
|
UTSW |
14 |
64,269,343 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1651:Rp1l1
|
UTSW |
14 |
64,268,442 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1682:Rp1l1
|
UTSW |
14 |
64,266,417 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1809:Rp1l1
|
UTSW |
14 |
64,265,415 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1885:Rp1l1
|
UTSW |
14 |
64,265,839 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1887:Rp1l1
|
UTSW |
14 |
64,265,839 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1898:Rp1l1
|
UTSW |
14 |
64,269,039 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1924:Rp1l1
|
UTSW |
14 |
64,268,992 (GRCm39) |
missense |
probably benign |
|
|
R1939:Rp1l1
|
UTSW |
14 |
64,267,042 (GRCm39) |
missense |
probably benign |
|
|
R1941:Rp1l1
|
UTSW |
14 |
64,259,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2129:Rp1l1
|
UTSW |
14 |
64,266,415 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2363:Rp1l1
|
UTSW |
14 |
64,267,447 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R3894:Rp1l1
|
UTSW |
14 |
64,266,756 (GRCm39) |
missense |
probably benign |
|
|
R3974:Rp1l1
|
UTSW |
14 |
64,267,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3975:Rp1l1
|
UTSW |
14 |
64,267,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3976:Rp1l1
|
UTSW |
14 |
64,267,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4072:Rp1l1
|
UTSW |
14 |
64,265,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4672:Rp1l1
|
UTSW |
14 |
64,268,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4673:Rp1l1
|
UTSW |
14 |
64,268,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4749:Rp1l1
|
UTSW |
14 |
64,267,249 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4755:Rp1l1
|
UTSW |
14 |
64,267,519 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4877:Rp1l1
|
UTSW |
14 |
64,263,620 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4930:Rp1l1
|
UTSW |
14 |
64,269,655 (GRCm39) |
missense |
probably benign |
|
|
R5039:Rp1l1
|
UTSW |
14 |
64,268,805 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5106:Rp1l1
|
UTSW |
14 |
64,265,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5184:Rp1l1
|
UTSW |
14 |
64,267,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5215:Rp1l1
|
UTSW |
14 |
64,267,462 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5409:Rp1l1
|
UTSW |
14 |
64,268,070 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5575:Rp1l1
|
UTSW |
14 |
64,268,433 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5696:Rp1l1
|
UTSW |
14 |
64,267,195 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5739:Rp1l1
|
UTSW |
14 |
64,269,619 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5878:Rp1l1
|
UTSW |
14 |
64,266,355 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6133:Rp1l1
|
UTSW |
14 |
64,267,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6134:Rp1l1
|
UTSW |
14 |
64,267,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6135:Rp1l1
|
UTSW |
14 |
64,267,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Rp1l1
|
UTSW |
14 |
64,269,838 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6594:Rp1l1
|
UTSW |
14 |
64,269,126 (GRCm39) |
nonsense |
probably null |
|
|
R6736:Rp1l1
|
UTSW |
14 |
64,267,173 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6800:Rp1l1
|
UTSW |
14 |
64,268,599 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6848:Rp1l1
|
UTSW |
14 |
64,265,667 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6878:Rp1l1
|
UTSW |
14 |
64,269,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6922:Rp1l1
|
UTSW |
14 |
64,267,834 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6980:Rp1l1
|
UTSW |
14 |
64,266,169 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7053:Rp1l1
|
UTSW |
14 |
64,268,958 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7151:Rp1l1
|
UTSW |
14 |
64,266,475 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7291:Rp1l1
|
UTSW |
14 |
64,269,747 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7335:Rp1l1
|
UTSW |
14 |
64,269,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7344:Rp1l1
|
UTSW |
14 |
64,267,069 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7470:Rp1l1
|
UTSW |
14 |
64,266,015 (GRCm39) |
missense |
probably benign |
|
|
R7570:Rp1l1
|
UTSW |
14 |
64,269,023 (GRCm39) |
nonsense |
probably null |
|
|
R7585:Rp1l1
|
UTSW |
14 |
64,267,588 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7591:Rp1l1
|
UTSW |
14 |
64,263,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7667:Rp1l1
|
UTSW |
14 |
64,267,252 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7862:Rp1l1
|
UTSW |
14 |
64,265,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7935:Rp1l1
|
UTSW |
14 |
64,268,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8256:Rp1l1
|
UTSW |
14 |
64,265,602 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8403:Rp1l1
|
UTSW |
14 |
64,266,258 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8709:Rp1l1
|
UTSW |
14 |
64,269,295 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8817:Rp1l1
|
UTSW |
14 |
64,268,085 (GRCm39) |
missense |
probably benign |
|
|
R8971:Rp1l1
|
UTSW |
14 |
64,259,445 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9380:Rp1l1
|
UTSW |
14 |
64,266,475 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9438:Rp1l1
|
UTSW |
14 |
64,265,574 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9501:Rp1l1
|
UTSW |
14 |
64,266,039 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9652:Rp1l1
|
UTSW |
14 |
64,269,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9683:Rp1l1
|
UTSW |
14 |
64,269,126 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0057:Rp1l1
|
UTSW |
14 |
64,267,489 (GRCm39) |
missense |
probably benign |
0.14 |
|
X0063:Rp1l1
|
UTSW |
14 |
64,266,672 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1088:Rp1l1
|
UTSW |
14 |
64,267,827 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1088:Rp1l1
|
UTSW |
14 |
64,266,207 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
Z1176:Rp1l1
|
UTSW |
14 |
64,266,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Rp1l1
|
UTSW |
14 |
64,269,746 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGGGGAAATCTGCATCGGCAC -3'
(R):5'- TCTCTCTGGATACATCACGGGGAC -3'
Sequencing Primer
(F):5'- TCGGCACTGCCCAAGAAAG -3'
(R):5'- TCTGAGACACCTGTGAACTG -3'
|
| Posted On |
2013-06-11 |
Incidental Mutation