Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03138:4933416I08Rik'

453092

Institutional Source

Beutler Lab

Gene Symbol

4933416I08Rik

Ensembl Gene

ENSMUSG00000071763

Gene Name

RIKEN cDNA 4933416I08 gene

Synonyms

Gm14597

Accession Numbers

Essential gene?

Probably essential (E-score: 0.870) question?

Stock #

IGL03138 (G1)

Quality Score

215

Status

Validated

Chromosome

Chromosomal Location

52576567-52608981 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

TCC to TCCC at 52692862 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000125315

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000192662

Coding Region Coverage

1x: 0.0%
3x: 0.0%
10x: 0.0%
20x: 0.0%

Validation Efficiency

95% (40/42)

Allele List at MGI

Other mutations in this stock

Total: 28 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Casd1	A	G	6: 4,613,236 (GRCm39)	H118R	probably damaging	Het
Cilp	TGGG	TGG	9: 65,187,412 (GRCm39)		probably null	Het
Cmya5	T	C	13: 93,201,850 (GRCm39)	K3371E	probably damaging	Het
Crb1	CG	C	1: 139,164,824 (GRCm39)		probably null	Het
Dpysl3	T	C	18: 43,458,859 (GRCm39)	T632A	probably benign	Het
Elapor1	T	A	3: 108,379,309 (GRCm39)	N392Y	probably benign	Het
Fbh1	T	C	2: 11,754,320 (GRCm39)		probably benign	Het
Fcna	G	C	2: 25,520,693 (GRCm39)		probably benign	Het
Gbe1	T	A	16: 70,325,951 (GRCm39)		probably benign	Het
Gm4876	T	G	6: 17,171,736 (GRCm39)		noncoding transcript	Het
Gvin-ps6	G	T	7: 106,023,650 (GRCm39)		noncoding transcript	Het
Hsd17b7	C	T	1: 169,780,649 (GRCm39)	E320K	probably damaging	Het
Inhba	T	A	13: 16,192,099 (GRCm39)	D73E	probably benign	Het
Kndc1	A	G	7: 139,519,791 (GRCm39)	N1717D	possibly damaging	Het
Knl1	G	T	2: 118,902,840 (GRCm39)	V1514F	probably damaging	Het
Map1b	C	T	13: 99,562,334 (GRCm39)	A2459T	unknown	Het
Mmp1a	TG	TGG	9: 7,465,083 (GRCm38)		probably null	Het
Pias2	T	C	18: 77,237,796 (GRCm39)		probably null	Het
Polr1b	T	C	2: 128,944,908 (GRCm39)	F68S	probably benign	Het
Skic8	T	C	9: 54,635,447 (GRCm39)		probably benign	Het
Slamf1	C	A	1: 171,604,652 (GRCm39)	Q141K	possibly damaging	Het
Speer4c1	A	C	5: 15,919,214 (GRCm39)		probably benign	Het
Tpo	T	C	12: 30,124,170 (GRCm39)	T877A	probably benign	Het
Ugt1a1	AT	A	1: 88,140,093 (GRCm39)		probably null	Het
Vmn1r37	A	G	6: 66,709,172 (GRCm39)	K229R	possibly damaging	Het
Wdr17	T	C	8: 55,102,178 (GRCm39)	D947G	probably damaging	Het
Wiz	G	T	17: 32,578,093 (GRCm39)	T473K	probably damaging	Het
Zmynd12	A	G	4: 119,280,186 (GRCm39)	Y35C	probably damaging	Het

Other mutations in 4933416I08Rik

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02528:4933416I08Rik	APN	X	52,580,792 (GRCm39)	missense	probably damaging	1.00
IGL02984:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript
IGL02988:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript
IGL02991:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript
IGL03014:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript
IGL03050:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript
IGL03054:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript
IGL03055:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript
IGL03097:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript
IGL03098:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript
IGL03134:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript
IGL03147:4933416I08Rik	UTSW	X	52,692,862 (GRCm39)	unclassified	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- TTGTCAGTATAGCAGGCAGGAC -3'
(R):5'- GGCACTCTGTTGTCCTGAAAG -3'

Sequencing Primer
(F):5'- TATAGCAGGCAGGACAGGAAAGC -3'
(R):5'- GCACTAAATGAGGCCCTCTATTGG -3'

Posted On

2017-01-27