Mutagenetix > Incidental Mutation

Incidental Mutation 'R5874:Ankrd17'

455374

Institutional Source

Beutler Lab

Gene Symbol

Ankrd17

Ensembl Gene

ENSMUSG00000055204

Gene Name

ankyrin repeat domain 17

Synonyms

Gtar, A130069E23Rik, 4933425K22Rik

MMRRC Submission

044081-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R5874 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

90375025-90514436 bp(-) (GRCm39)

Type of Mutation

intron

DNA Base Change (assembly)

T to C at 90416656 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000151446 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000014421] [ENSMUST00000081914] [ENSMUST00000168058] [ENSMUST00000197021] [ENSMUST00000218526]

AlphaFold

Q99NH0

Predicted Effect

probably benign
Transcript: ENSMUST00000014421

SMART Domains

Protein: ENSMUSP00000014421
Gene: ENSMUSG00000055204

Domain	Start	End	E-Value	Type
low complexity region	6	40	N/A	INTRINSIC
low complexity region	55	71	N/A	INTRINSIC
low complexity region	82	130	N/A	INTRINSIC
ANK	229	258	8.62e1	SMART
ANK	262	291	3.31e-1	SMART
ANK	296	325	3.51e-5	SMART
ANK	329	358	1.33e-5	SMART
ANK	362	391	3.46e-4	SMART
ANK	396	425	3.23e-4	SMART
ANK	429	458	1.61e-4	SMART
ANK	462	491	1.46e-2	SMART
ANK	495	524	3.88e-7	SMART
ANK	529	558	4.19e-3	SMART
ANK	559	588	1.76e-5	SMART
ANK	592	621	3.51e-5	SMART
ANK	625	654	5.62e-4	SMART
ANK	659	688	1.29e-3	SMART
ANK	692	721	1.44e-1	SMART
coiled coil region	800	883	N/A	INTRINSIC
low complexity region	890	903	N/A	INTRINSIC
low complexity region	955	968	N/A	INTRINSIC
low complexity region	986	997	N/A	INTRINSIC
low complexity region	1046	1060	N/A	INTRINSIC
ANK	1078	1107	2.13e-4	SMART
ANK	1111	1140	8.19e-6	SMART
ANK	1145	1174	1.68e-2	SMART
ANK	1178	1207	1.61e-4	SMART
ANK	1213	1242	1.43e-5	SMART
ANK	1247	1276	1.83e-3	SMART
ANK	1280	1309	3.91e-3	SMART
ANK	1315	1344	1.93e-2	SMART
ANK	1348	1377	8.78e-6	SMART
ANK	1381	1410	7.59e-1	SMART
coiled coil region	1454	1522	N/A	INTRINSIC
low complexity region	1597	1611	N/A	INTRINSIC
low complexity region	1616	1636	N/A	INTRINSIC
KH	1720	1790	8.31e-14	SMART
low complexity region	1816	1827	N/A	INTRINSIC
low complexity region	1834	1850	N/A	INTRINSIC
low complexity region	1946	1989	N/A	INTRINSIC
low complexity region	1996	2024	N/A	INTRINSIC
low complexity region	2035	2052	N/A	INTRINSIC
low complexity region	2068	2077	N/A	INTRINSIC
low complexity region	2086	2110	N/A	INTRINSIC
low complexity region	2175	2189	N/A	INTRINSIC
low complexity region	2348	2365	N/A	INTRINSIC
low complexity region	2392	2411	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000081914

SMART Domains

Protein: ENSMUSP00000080587
Gene: ENSMUSG00000055204

Domain	Start	End	E-Value	Type
low complexity region	6	40	N/A	INTRINSIC
low complexity region	55	71	N/A	INTRINSIC
low complexity region	82	130	N/A	INTRINSIC
ANK	229	258	8.62e1	SMART
ANK	262	291	3.31e-1	SMART
ANK	296	325	3.51e-5	SMART
ANK	329	358	1.33e-5	SMART
ANK	362	391	3.46e-4	SMART
ANK	396	425	3.23e-4	SMART
ANK	429	458	1.61e-4	SMART
ANK	462	491	1.46e-2	SMART
ANK	495	524	3.88e-7	SMART
ANK	529	558	4.19e-3	SMART
ANK	559	588	1.76e-5	SMART
ANK	592	621	3.51e-5	SMART
ANK	625	654	5.62e-4	SMART
ANK	659	688	1.29e-3	SMART
ANK	692	721	1.44e-1	SMART
low complexity region	795	809	N/A	INTRINSIC
ANK	827	856	2.13e-4	SMART
ANK	860	889	8.19e-6	SMART
ANK	894	923	1.68e-2	SMART
ANK	927	956	1.61e-4	SMART
ANK	962	991	1.43e-5	SMART
ANK	996	1025	1.83e-3	SMART
ANK	1029	1058	3.91e-3	SMART
ANK	1064	1093	1.93e-2	SMART
ANK	1097	1126	8.78e-6	SMART
ANK	1130	1159	7.59e-1	SMART
coiled coil region	1203	1271	N/A	INTRINSIC
low complexity region	1346	1360	N/A	INTRINSIC
low complexity region	1365	1385	N/A	INTRINSIC
KH	1469	1539	8.31e-14	SMART
low complexity region	1565	1576	N/A	INTRINSIC
low complexity region	1583	1599	N/A	INTRINSIC
low complexity region	1695	1738	N/A	INTRINSIC
low complexity region	1745	1773	N/A	INTRINSIC
low complexity region	1784	1801	N/A	INTRINSIC
low complexity region	1817	1826	N/A	INTRINSIC
low complexity region	1835	1859	N/A	INTRINSIC
low complexity region	1924	1938	N/A	INTRINSIC
low complexity region	2097	2114	N/A	INTRINSIC
low complexity region	2141	2160	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000168058

SMART Domains

Protein: ENSMUSP00000128960
Gene: ENSMUSG00000055204

Domain	Start	End	E-Value	Type
low complexity region	6	40	N/A	INTRINSIC
low complexity region	55	71	N/A	INTRINSIC
low complexity region	82	130	N/A	INTRINSIC
ANK	229	258	8.62e1	SMART
ANK	262	291	3.31e-1	SMART
ANK	296	325	3.51e-5	SMART
ANK	329	358	1.33e-5	SMART
ANK	362	391	3.46e-4	SMART
ANK	396	425	3.23e-4	SMART
ANK	429	458	1.61e-4	SMART
ANK	462	491	1.46e-2	SMART
ANK	495	524	3.88e-7	SMART
ANK	529	558	4.19e-3	SMART
ANK	559	588	1.76e-5	SMART
ANK	592	621	3.51e-5	SMART
ANK	625	654	5.62e-4	SMART
ANK	659	688	1.29e-3	SMART
ANK	692	721	1.44e-1	SMART
coiled coil region	800	883	N/A	INTRINSIC
low complexity region	890	903	N/A	INTRINSIC
low complexity region	955	968	N/A	INTRINSIC
low complexity region	986	997	N/A	INTRINSIC
low complexity region	1046	1060	N/A	INTRINSIC
ANK	1078	1107	2.13e-4	SMART
ANK	1111	1140	8.19e-6	SMART
ANK	1145	1174	1.68e-2	SMART
ANK	1178	1207	1.61e-4	SMART
ANK	1213	1242	1.43e-5	SMART
ANK	1247	1276	1.83e-3	SMART
ANK	1280	1309	3.91e-3	SMART
ANK	1315	1344	1.93e-2	SMART
ANK	1348	1377	8.78e-6	SMART
ANK	1381	1410	7.59e-1	SMART
coiled coil region	1454	1522	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000197021

SMART Domains

Protein: ENSMUSP00000142575
Gene: ENSMUSG00000055204

Domain	Start	End	E-Value	Type
ANK	120	149	5.4e-1	SMART
ANK	153	182	2e-3	SMART
ANK	187	216	2.2e-7	SMART
ANK	220	249	8.2e-8	SMART
ANK	253	282	2.2e-6	SMART
ANK	287	316	2.1e-6	SMART
ANK	320	349	9.9e-7	SMART
ANK	353	382	9.5e-5	SMART
ANK	386	415	2.4e-9	SMART
ANK	420	449	2.6e-5	SMART
ANK	450	479	1.1e-7	SMART
ANK	483	512	2.2e-7	SMART
ANK	516	545	3.5e-6	SMART
ANK	550	579	7.9e-6	SMART
ANK	583	612	8.9e-4	SMART
coiled coil region	691	774	N/A	INTRINSIC
low complexity region	781	794	N/A	INTRINSIC
low complexity region	846	859	N/A	INTRINSIC
low complexity region	877	888	N/A	INTRINSIC
low complexity region	937	951	N/A	INTRINSIC
ANK	969	998	1.4e-6	SMART
ANK	1002	1031	5.3e-8	SMART
ANK	1036	1065	1e-4	SMART
ANK	1069	1098	1e-6	SMART
ANK	1104	1133	9.1e-8	SMART
ANK	1138	1167	1.2e-5	SMART
ANK	1171	1200	2.5e-5	SMART
ANK	1206	1235	1.2e-4	SMART
ANK	1239	1268	5.5e-8	SMART
ANK	1272	1301	4.7e-3	SMART
coiled coil region	1345	1413	N/A	INTRINSIC
low complexity region	1488	1502	N/A	INTRINSIC
low complexity region	1507	1527	N/A	INTRINSIC
KH	1611	1681	5.1e-16	SMART
low complexity region	1707	1718	N/A	INTRINSIC
low complexity region	1725	1741	N/A	INTRINSIC
low complexity region	1837	1880	N/A	INTRINSIC
low complexity region	1887	1915	N/A	INTRINSIC
low complexity region	1926	1943	N/A	INTRINSIC
low complexity region	1959	1968	N/A	INTRINSIC
low complexity region	1977	2001	N/A	INTRINSIC
low complexity region	2066	2080	N/A	INTRINSIC
low complexity region	2239	2256	N/A	INTRINSIC
low complexity region	2283	2302	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000197037

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000199424

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000200012

Predicted Effect

probably benign
Transcript: ENSMUST00000218526

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.9%
3x: 99.5%
10x: 97.8%
20x: 93.6%

Validation Efficiency

98% (86/88)

MGI Phenotype

FUNCTION: This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies suggest that this protein is involved in liver development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality during organogenesis with hemorrhages, impaired vascular smooth muscle cell development, impaired vascular integrity, and growth retardation. [provided by MGI curators]

Allele List at MGI

All alleles(133) : Targeted(4) Gene trapped(129)

Other mutations in this stock

Total: 73 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930432E11Rik	G	A	7: 29,280,610 (GRCm39)		noncoding transcript	Het
Adam17	T	C	12: 21,379,087 (GRCm39)	D654G	possibly damaging	Het
Ankhd1	A	T	18: 36,773,322 (GRCm39)	H1373L	possibly damaging	Het
Calu	A	G	6: 29,372,617 (GRCm39)	D112G	probably damaging	Het
Camk2a	G	C	18: 61,076,272 (GRCm39)		probably benign	Het
Cpn1	C	A	19: 43,944,951 (GRCm39)	R452L	probably benign	Het
Csmd3	T	A	15: 47,507,666 (GRCm39)	E2780V	probably damaging	Het
Ctnna2	T	C	6: 76,879,413 (GRCm39)	T824A	probably benign	Het
Cuedc2	C	T	19: 46,319,824 (GRCm39)	V164M	possibly damaging	Het
Cyp2d34	T	A	15: 82,503,243 (GRCm39)	D74V	probably benign	Het
Ddi2	A	G	4: 141,422,780 (GRCm39)	S311P	probably damaging	Het
Ddx10	A	C	9: 53,140,498 (GRCm39)	I301R	possibly damaging	Het
Dmpk	T	C	7: 18,826,007 (GRCm39)		probably benign	Het
Dnah7b	C	T	1: 46,230,885 (GRCm39)	T1381I	probably damaging	Het
Dst	T	A	1: 34,218,670 (GRCm39)	N1703K	probably damaging	Het
Dtwd1	T	A	2: 126,000,359 (GRCm39)	H98Q	probably damaging	Het
Ecel1	A	C	1: 87,075,731 (GRCm39)	V769G	probably benign	Het
Eno4	T	C	19: 58,935,238 (GRCm39)	V150A	probably benign	Het
Evc2	C	T	5: 37,574,883 (GRCm39)		probably benign	Het
Ext1	T	A	15: 52,965,148 (GRCm39)	Q406L	possibly damaging	Het
Foxf2	A	G	13: 31,810,775 (GRCm39)	H238R	probably benign	Het
Frem2	C	G	3: 53,444,910 (GRCm39)	G2407A	probably benign	Het
Fzd10	A	G	5: 128,678,364 (GRCm39)	E28G	probably benign	Het
Galnt15	T	C	14: 31,774,324 (GRCm39)	F363L	probably damaging	Het
Gm1758	C	T	16: 14,325,037 (GRCm39)		noncoding transcript	Het
Gm5866	C	T	5: 52,739,956 (GRCm39)		noncoding transcript	Het
Heatr9	T	A	11: 83,405,426 (GRCm39)	M345L	probably benign	Het
Il23r	A	T	6: 67,408,629 (GRCm39)	F404Y	possibly damaging	Het
Lrrc8a	T	C	2: 30,147,148 (GRCm39)	I654T	probably damaging	Het
Napg	A	T	18: 63,111,091 (GRCm39)	K18*	probably null	Het
Ndst3	A	T	3: 123,355,556 (GRCm39)	W573R	probably damaging	Het
Nin	T	C	12: 70,077,692 (GRCm39)	S1038G	possibly damaging	Het
Nudt12	T	A	17: 59,317,279 (GRCm39)	R123*	probably null	Het
Oas1g	T	A	5: 121,015,081 (GRCm39)	N361Y	probably benign	Het
Or5p51	T	A	7: 107,444,377 (GRCm39)	I188L	probably benign	Het
Or7a35	T	A	10: 78,853,191 (GRCm39)	F12I	possibly damaging	Het
Or8h10	A	T	2: 86,808,786 (GRCm39)	M118K	probably damaging	Het
Osbpl10	T	C	9: 115,055,828 (GRCm39)	F667L	probably damaging	Het
Phldb2	T	C	16: 45,621,988 (GRCm39)	D664G	probably damaging	Het
Piezo2	C	T	18: 63,160,972 (GRCm39)	V2263M	probably damaging	Het
Pkd1l1	A	G	11: 8,858,688 (GRCm39)	L615P	probably damaging	Het
Pnpla7	G	A	2: 24,901,661 (GRCm39)	M562I	probably benign	Het
Pou2af2	A	T	9: 51,201,672 (GRCm39)	L128*	probably null	Het
Ppp1r13b	C	A	12: 111,811,423 (GRCm39)	R155L	probably damaging	Het
Pygb	C	T	2: 150,628,798 (GRCm39)	P4L	probably benign	Het
Rbm44	T	C	1: 91,084,562 (GRCm39)		probably null	Het
Rilpl2	T	C	5: 124,607,876 (GRCm39)	T115A	probably benign	Het
Rin3	A	G	12: 102,356,102 (GRCm39)	Y801C	probably damaging	Het
Rnf112	A	G	11: 61,340,273 (GRCm39)	V619A	probably damaging	Het
Rnf182	A	G	13: 43,821,563 (GRCm39)	E38G	probably benign	Het
Scgb2b24	T	A	7: 33,436,830 (GRCm39)	Y94F	probably damaging	Het
Serac1	C	A	17: 6,094,188 (GRCm39)		probably benign	Het
Shld2	T	C	14: 33,967,215 (GRCm39)	T114A	probably benign	Het
Slc6a19	A	T	13: 73,832,487 (GRCm39)	V402D	probably damaging	Het
Slco1a8	A	T	6: 141,917,961 (GRCm39)	H638Q	probably benign	Het
Slco2b1	T	A	7: 99,316,301 (GRCm39)	M410L	probably benign	Het
Smarca2	T	C	19: 26,753,469 (GRCm39)		probably benign	Het
Sned1	A	G	1: 93,193,067 (GRCm39)	Y409C	probably damaging	Het
Sorcs2	A	G	5: 36,386,555 (GRCm39)	V161A	probably damaging	Het
Spring1	T	C	5: 118,397,504 (GRCm39)	V162A	probably damaging	Het
Sptb	T	C	12: 76,645,501 (GRCm39)	E2029G	possibly damaging	Het
Stx7	T	A	10: 24,058,659 (GRCm39)		probably null	Het
Taf4b	T	C	18: 14,937,611 (GRCm39)	V228A	probably benign	Het
Tbc1d1	A	G	5: 64,507,273 (GRCm39)	*1163W	probably null	Het
Tor4a	G	A	2: 25,084,847 (GRCm39)	A352V	probably damaging	Het
Trpm4	A	G	7: 44,977,173 (GRCm39)	F81S	probably damaging	Het
Ttn	T	A	2: 76,780,436 (GRCm39)	D1105V	probably damaging	Het
Vcf1	T	A	11: 113,568,220 (GRCm39)	R78S	probably damaging	Het
Yju2b	T	A	8: 84,985,177 (GRCm39)	D364V	possibly damaging	Het
Zfp551	A	G	7: 12,150,101 (GRCm39)	L436P	probably damaging	Het
Zfp975	G	T	7: 42,312,312 (GRCm39)	D100E	probably benign	Het
Zswim3	A	G	2: 164,662,032 (GRCm39)	I171V	probably benign	Het
Zwint	C	T	10: 72,492,294 (GRCm39)		probably benign	Het

Other mutations in Ankrd17

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00236:Ankrd17	APN	5	90,381,787 (GRCm39)	missense	probably damaging	0.98
IGL00484:Ankrd17	APN	5	90,416,220 (GRCm39)	missense	probably damaging	0.99
IGL01320:Ankrd17	APN	5	90,407,988 (GRCm39)	missense	probably damaging	0.99
IGL01776:Ankrd17	APN	5	90,431,223 (GRCm39)	nonsense	probably null
IGL02093:Ankrd17	APN	5	90,390,822 (GRCm39)	missense	possibly damaging	0.93
IGL02292:Ankrd17	APN	5	90,400,718 (GRCm39)	unclassified	probably benign
IGL02302:Ankrd17	APN	5	90,431,057 (GRCm39)	missense	probably benign	0.23
IGL02472:Ankrd17	APN	5	90,412,010 (GRCm39)	missense	probably damaging	1.00
IGL02705:Ankrd17	APN	5	90,430,974 (GRCm39)	missense	probably benign	0.15
IGL02727:Ankrd17	APN	5	90,392,151 (GRCm39)	missense	possibly damaging	0.93
IGL02884:Ankrd17	APN	5	90,412,616 (GRCm39)	missense	probably damaging	1.00
3-1:Ankrd17	UTSW	5	90,391,013 (GRCm39)	missense	probably damaging	0.99
PIT1430001:Ankrd17	UTSW	5	90,400,832 (GRCm39)	missense	possibly damaging	0.91
R0025:Ankrd17	UTSW	5	90,398,264 (GRCm39)	missense	probably damaging	0.99
R0076:Ankrd17	UTSW	5	90,392,265 (GRCm39)	nonsense	probably null
R0076:Ankrd17	UTSW	5	90,392,265 (GRCm39)	nonsense	probably null
R0271:Ankrd17	UTSW	5	90,402,658 (GRCm39)	missense	possibly damaging	0.90
R0684:Ankrd17	UTSW	5	90,411,857 (GRCm39)	missense	probably damaging	0.99
R1239:Ankrd17	UTSW	5	90,436,535 (GRCm39)	missense	probably damaging	0.99
R1457:Ankrd17	UTSW	5	90,433,705 (GRCm39)	missense	possibly damaging	0.92
R1505:Ankrd17	UTSW	5	90,447,885 (GRCm39)	missense	possibly damaging	0.53
R1766:Ankrd17	UTSW	5	90,412,656 (GRCm39)	missense	possibly damaging	0.95
R1770:Ankrd17	UTSW	5	90,391,235 (GRCm39)	missense	possibly damaging	0.84
R1780:Ankrd17	UTSW	5	90,380,274 (GRCm39)	missense	probably damaging	0.96
R1916:Ankrd17	UTSW	5	90,408,000 (GRCm39)	missense	probably damaging	1.00
R1926:Ankrd17	UTSW	5	90,392,028 (GRCm39)	missense	probably damaging	1.00
R2090:Ankrd17	UTSW	5	90,445,905 (GRCm39)	missense	possibly damaging	0.92
R2153:Ankrd17	UTSW	5	90,381,918 (GRCm39)	missense	probably damaging	0.98
R2279:Ankrd17	UTSW	5	90,412,576 (GRCm39)	missense	probably damaging	1.00
R2420:Ankrd17	UTSW	5	90,437,179 (GRCm39)	missense	possibly damaging	0.94
R3012:Ankrd17	UTSW	5	90,378,727 (GRCm39)	missense	probably damaging	1.00
R3417:Ankrd17	UTSW	5	90,391,772 (GRCm39)	missense	possibly damaging	0.86
R3704:Ankrd17	UTSW	5	90,391,828 (GRCm39)	missense	possibly damaging	0.72
R4581:Ankrd17	UTSW	5	90,430,979 (GRCm39)	missense	possibly damaging	0.67
R4850:Ankrd17	UTSW	5	90,412,645 (GRCm39)	missense	probably damaging	1.00
R4926:Ankrd17	UTSW	5	90,447,891 (GRCm39)	missense	probably damaging	1.00
R5023:Ankrd17	UTSW	5	90,430,727 (GRCm39)	missense	probably damaging	1.00
R5068:Ankrd17	UTSW	5	90,402,667 (GRCm39)	missense	probably damaging	0.96
R5109:Ankrd17	UTSW	5	90,391,395 (GRCm39)	missense	possibly damaging	0.83
R5111:Ankrd17	UTSW	5	90,390,858 (GRCm39)	missense	possibly damaging	0.85
R5214:Ankrd17	UTSW	5	90,431,319 (GRCm39)	missense	possibly damaging	0.48
R5362:Ankrd17	UTSW	5	90,413,404 (GRCm39)	missense	probably damaging	1.00
R5576:Ankrd17	UTSW	5	90,391,083 (GRCm39)	missense	probably benign	0.00
R5615:Ankrd17	UTSW	5	90,431,295 (GRCm39)	missense	possibly damaging	0.88
R5932:Ankrd17	UTSW	5	90,413,295 (GRCm39)	missense	probably damaging	1.00
R5944:Ankrd17	UTSW	5	90,433,702 (GRCm39)	missense	probably damaging	1.00
R5993:Ankrd17	UTSW	5	90,487,531 (GRCm39)	intron	probably benign
R6052:Ankrd17	UTSW	5	90,401,691 (GRCm39)	missense	probably benign	0.03
R6088:Ankrd17	UTSW	5	90,401,547 (GRCm39)	missense	possibly damaging	0.95
R6306:Ankrd17	UTSW	5	90,392,013 (GRCm39)	missense	probably benign	0.03
R6418:Ankrd17	UTSW	5	90,426,204 (GRCm39)	missense	possibly damaging	0.89
R6663:Ankrd17	UTSW	5	90,411,923 (GRCm39)	missense	probably damaging	1.00
R6758:Ankrd17	UTSW	5	90,411,172 (GRCm39)	missense	probably damaging	1.00
R6782:Ankrd17	UTSW	5	90,402,597 (GRCm39)	missense	possibly damaging	0.91
R6793:Ankrd17	UTSW	5	90,413,371 (GRCm39)	missense	probably damaging	1.00
R6929:Ankrd17	UTSW	5	90,433,384 (GRCm39)	missense	possibly damaging	0.86
R7008:Ankrd17	UTSW	5	90,407,955 (GRCm39)	missense	possibly damaging	0.93
R7051:Ankrd17	UTSW	5	90,514,310 (GRCm39)	unclassified	probably benign
R7077:Ankrd17	UTSW	5	90,433,723 (GRCm39)	missense	possibly damaging	0.92
R7134:Ankrd17	UTSW	5	90,433,382 (GRCm39)	missense	probably benign	0.03
R7134:Ankrd17	UTSW	5	90,380,173 (GRCm39)	missense	probably damaging	0.99
R7138:Ankrd17	UTSW	5	90,390,836 (GRCm39)	missense	probably benign	0.38
R7143:Ankrd17	UTSW	5	90,433,820 (GRCm39)	missense	possibly damaging	0.85
R7173:Ankrd17	UTSW	5	90,407,976 (GRCm39)	missense	possibly damaging	0.95
R7176:Ankrd17	UTSW	5	90,416,594 (GRCm39)	missense	probably damaging	0.99
R7365:Ankrd17	UTSW	5	90,439,010 (GRCm39)	missense	possibly damaging	0.45
R7390:Ankrd17	UTSW	5	90,430,779 (GRCm39)	missense	probably benign	0.13
R7430:Ankrd17	UTSW	5	90,443,516 (GRCm39)	missense	possibly damaging	0.80
R7468:Ankrd17	UTSW	5	90,390,902 (GRCm39)	missense	probably benign
R7483:Ankrd17	UTSW	5	90,447,855 (GRCm39)	missense	probably benign	0.00
R7492:Ankrd17	UTSW	5	90,381,807 (GRCm39)	missense	possibly damaging	0.85
R7610:Ankrd17	UTSW	5	90,380,222 (GRCm39)	missense	possibly damaging	0.93
R7636:Ankrd17	UTSW	5	90,380,239 (GRCm39)	missense	possibly damaging	0.53
R7790:Ankrd17	UTSW	5	90,408,011 (GRCm39)	missense	possibly damaging	0.61
R7839:Ankrd17	UTSW	5	90,411,213 (GRCm39)	missense	probably damaging	0.97
R7853:Ankrd17	UTSW	5	90,386,825 (GRCm39)	missense	possibly damaging	0.91
R7976:Ankrd17	UTSW	5	90,431,451 (GRCm39)	nonsense	probably null
R8054:Ankrd17	UTSW	5	90,438,914 (GRCm39)	missense	probably benign	0.43
R8230:Ankrd17	UTSW	5	90,391,835 (GRCm39)	missense	possibly damaging	0.86
R8274:Ankrd17	UTSW	5	90,430,718 (GRCm39)	missense	probably benign	0.15
R8365:Ankrd17	UTSW	5	90,398,378 (GRCm39)	missense	possibly damaging	0.95
R8532:Ankrd17	UTSW	5	90,412,679 (GRCm39)	missense	probably damaging	1.00
R8729:Ankrd17	UTSW	5	90,443,452 (GRCm39)	missense	probably benign
R8812:Ankrd17	UTSW	5	90,441,062 (GRCm39)	missense	probably benign	0.09
R8933:Ankrd17	UTSW	5	90,406,325 (GRCm39)	missense	probably damaging	0.99
R9051:Ankrd17	UTSW	5	90,411,134 (GRCm39)	missense	probably damaging	0.99
R9055:Ankrd17	UTSW	5	90,380,168 (GRCm39)	missense	probably benign	0.33
R9136:Ankrd17	UTSW	5	90,392,278 (GRCm39)	missense	probably damaging	0.96
R9158:Ankrd17	UTSW	5	90,416,575 (GRCm39)	missense	probably damaging	1.00
R9201:Ankrd17	UTSW	5	90,378,798 (GRCm39)	missense	possibly damaging	0.84
R9315:Ankrd17	UTSW	5	90,398,360 (GRCm39)	missense	probably damaging	0.97
R9364:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9366:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9368:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9368:Ankrd17	UTSW	5	90,391,986 (GRCm39)	missense	possibly damaging	0.91
R9369:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9381:Ankrd17	UTSW	5	90,416,508 (GRCm39)	missense	probably damaging	1.00
R9570:Ankrd17	UTSW	5	90,401,536 (GRCm39)	missense
X0019:Ankrd17	UTSW	5	90,446,513 (GRCm39)	missense	probably damaging	1.00
Z1177:Ankrd17	UTSW	5	90,437,184 (GRCm39)	missense	possibly damaging	0.86
Z1177:Ankrd17	UTSW	5	90,431,364 (GRCm39)	missense	possibly damaging	0.83

Predicted Primers

PCR Primer
(F):5'- CCAATACTTGGCTATAAGCTGTTG -3'
(R):5'- GTTTGGCTAGTCATTGATAGAAGAG -3'

Sequencing Primer
(F):5'- AACTGACAAAAATAAGGGCTACC -3'
(R):5'- GTTGTTAGTAAACCACATAGCATCC -3'

Posted On

2017-02-10