Incidental Mutation 'R5875:Abcc1'
| ID |
455497 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abcc1
|
| Ensembl Gene |
ENSMUSG00000023088 |
| Gene Name |
ATP-binding cassette, sub-family C member 1 |
| Synonyms |
Mdrap, Mrp1, MRP, Abcc1b, Abcc1a |
| MMRRC Submission |
044082-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.164)
|
| Stock # |
R5875 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
14179317-14292743 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 14284901 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 1250
(E1250G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097743
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100167]
[ENSMUST00000130671]
[ENSMUST00000133454]
[ENSMUST00000147759]
|
| AlphaFold |
O35379 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000100167
AA Change: E1250G
PolyPhen 2
Score 0.938 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000097743
Gene: ENSMUSG00000023088
AA Change: E1250G
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
38 |
57 |
N/A |
INTRINSIC |
|
transmembrane domain
|
77 |
94 |
N/A |
INTRINSIC |
|
transmembrane domain
|
104 |
126 |
N/A |
INTRINSIC |
|
transmembrane domain
|
139 |
161 |
N/A |
INTRINSIC |
|
transmembrane domain
|
176 |
198 |
N/A |
INTRINSIC |
|
low complexity region
|
279 |
290 |
N/A |
INTRINSIC |
|
Pfam:ABC_membrane
|
326 |
597 |
7.8e-44 |
PFAM |
|
AAA
|
670 |
845 |
4.07e-8 |
SMART |
|
Pfam:ABC_membrane
|
971 |
1243 |
3e-52 |
PFAM |
|
AAA
|
1316 |
1501 |
5.8e-13 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000130671
|
| SMART Domains |
Protein: ENSMUSP00000116714
Gene: ENSMUSG00000023088
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
38 |
57 |
N/A |
INTRINSIC |
|
transmembrane domain
|
77 |
94 |
N/A |
INTRINSIC |
|
transmembrane domain
|
104 |
126 |
N/A |
INTRINSIC |
|
transmembrane domain
|
139 |
161 |
N/A |
INTRINSIC |
|
transmembrane domain
|
176 |
198 |
N/A |
INTRINSIC |
|
low complexity region
|
279 |
290 |
N/A |
INTRINSIC |
|
Pfam:ABC_membrane
|
326 |
597 |
1.6e-48 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000133454
|
| SMART Domains |
Protein: ENSMUSP00000122656
Gene: ENSMUSG00000023088
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
38 |
57 |
N/A |
INTRINSIC |
|
transmembrane domain
|
77 |
94 |
N/A |
INTRINSIC |
|
transmembrane domain
|
104 |
126 |
N/A |
INTRINSIC |
|
transmembrane domain
|
139 |
161 |
N/A |
INTRINSIC |
|
transmembrane domain
|
176 |
198 |
N/A |
INTRINSIC |
|
low complexity region
|
279 |
290 |
N/A |
INTRINSIC |
|
Pfam:ABC_membrane
|
326 |
597 |
1.6e-48 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134960
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146032
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000147759
|
| SMART Domains |
Protein: ENSMUSP00000115627
Gene: ENSMUSG00000023088
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
38 |
57 |
N/A |
INTRINSIC |
|
transmembrane domain
|
77 |
94 |
N/A |
INTRINSIC |
|
transmembrane domain
|
104 |
126 |
N/A |
INTRINSIC |
|
transmembrane domain
|
139 |
161 |
N/A |
INTRINSIC |
|
transmembrane domain
|
176 |
198 |
N/A |
INTRINSIC |
|
low complexity region
|
279 |
290 |
N/A |
INTRINSIC |
|
Pfam:ABC_membrane
|
326 |
597 |
1.6e-48 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.4%
- 10x: 97.4%
- 20x: 91.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein plays an essential role in the defense against toxic compounds and serves as the major high-affinity transporter of leukotriene C4. The encoded protein may also play an essential role in steroid hormone homeostasis as a transporter for steroid hormones and their metabolites. [provided by RefSeq, Nov 2011]
PHENOTYPE: Mice homozygous for targeted mutations that inactivate the gene have a reduced response to inflammatory stimulus, increased levels of glutathione due to impaired metabolism, and are hypersensitive to the anticancer drug etoposide. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1810024B03Rik |
A |
G |
2: 127,028,737 (GRCm39) |
V154A |
possibly damaging |
Het |
| Ajap1 |
A |
C |
4: 153,516,798 (GRCm39) |
I181R |
probably damaging |
Het |
| Akap9 |
A |
G |
5: 4,127,285 (GRCm39) |
Y3711C |
probably benign |
Het |
| Ark2c |
T |
C |
18: 77,650,877 (GRCm39) |
|
probably benign |
Het |
| Arl1 |
T |
C |
10: 88,577,841 (GRCm39) |
S137P |
probably benign |
Het |
| Atp6v0a2 |
G |
A |
5: 124,793,391 (GRCm39) |
V583I |
probably benign |
Het |
| Cdca7 |
T |
A |
2: 72,313,901 (GRCm39) |
M230K |
probably benign |
Het |
| Chd9 |
A |
T |
8: 91,778,464 (GRCm39) |
D2841V |
probably damaging |
Het |
| Chp1 |
T |
A |
2: 119,402,296 (GRCm39) |
F90Y |
probably damaging |
Het |
| Ckap5 |
A |
G |
2: 91,391,206 (GRCm39) |
T345A |
probably benign |
Het |
| Clca4b |
A |
C |
3: 144,628,650 (GRCm39) |
S352R |
probably benign |
Het |
| Cmya5 |
A |
G |
13: 93,231,692 (GRCm39) |
V1132A |
probably benign |
Het |
| Crb2 |
T |
A |
2: 37,677,266 (GRCm39) |
|
probably null |
Het |
| Crhbp |
A |
G |
13: 95,580,304 (GRCm39) |
F99L |
probably benign |
Het |
| Dnmt3l |
A |
T |
10: 77,889,772 (GRCm39) |
M210L |
probably benign |
Het |
| Dyrk2 |
T |
A |
10: 118,696,602 (GRCm39) |
R219W |
probably damaging |
Het |
| Exosc1 |
A |
G |
19: 41,916,542 (GRCm39) |
I78T |
probably damaging |
Het |
| Exosc9 |
T |
C |
3: 36,615,342 (GRCm39) |
|
probably null |
Het |
| Frmd5 |
A |
G |
2: 121,388,959 (GRCm39) |
|
probably benign |
Het |
| Gata2 |
T |
C |
6: 88,179,473 (GRCm39) |
L315P |
probably damaging |
Het |
| Gm17067 |
G |
A |
7: 42,357,470 (GRCm39) |
T344I |
probably benign |
Het |
| Gm4884 |
A |
T |
7: 40,692,360 (GRCm39) |
T110S |
possibly damaging |
Het |
| Hapln3 |
T |
C |
7: 78,771,721 (GRCm39) |
E56G |
probably benign |
Het |
| Helq |
A |
C |
5: 100,944,336 (GRCm39) |
I258S |
probably damaging |
Het |
| Hoxd10 |
T |
C |
2: 74,522,426 (GRCm39) |
Y35H |
possibly damaging |
Het |
| Inpp5b |
T |
C |
4: 124,674,199 (GRCm39) |
V302A |
possibly damaging |
Het |
| Inpp5d |
T |
A |
1: 87,645,696 (GRCm39) |
I1027N |
possibly damaging |
Het |
| Ints2 |
T |
C |
11: 86,129,138 (GRCm39) |
S482G |
probably benign |
Het |
| Itih1 |
C |
T |
14: 30,651,487 (GRCm39) |
V902I |
probably benign |
Het |
| Jkampl |
T |
C |
6: 73,446,028 (GRCm39) |
I174V |
possibly damaging |
Het |
| Kctd16 |
T |
A |
18: 40,390,447 (GRCm39) |
|
probably benign |
Het |
| Kif27 |
T |
C |
13: 58,458,918 (GRCm39) |
N971S |
probably benign |
Het |
| Klra17 |
T |
C |
6: 129,851,791 (GRCm39) |
D27G |
probably benign |
Het |
| Leo1 |
G |
C |
9: 75,357,842 (GRCm39) |
R412S |
probably damaging |
Het |
| Lonrf2 |
T |
C |
1: 38,846,128 (GRCm39) |
N348S |
probably benign |
Het |
| Lpp |
G |
A |
16: 24,427,059 (GRCm39) |
G62E |
probably benign |
Het |
| Lyn |
G |
A |
4: 3,745,631 (GRCm39) |
|
probably null |
Het |
| Macf1 |
T |
A |
4: 123,326,107 (GRCm39) |
N5128I |
possibly damaging |
Het |
| Mapk7 |
T |
A |
11: 61,384,524 (GRCm39) |
I61L |
probably benign |
Het |
| Mindy1 |
T |
C |
3: 95,202,125 (GRCm39) |
V334A |
probably damaging |
Het |
| Muc20 |
G |
A |
16: 32,614,189 (GRCm39) |
T396I |
possibly damaging |
Het |
| Myo5b |
A |
T |
18: 74,840,973 (GRCm39) |
|
probably null |
Het |
| Noc4l |
A |
C |
5: 110,799,176 (GRCm39) |
|
probably null |
Het |
| Oas1c |
A |
G |
5: 120,943,627 (GRCm39) |
Y171H |
probably damaging |
Het |
| Pclo |
A |
T |
5: 14,730,614 (GRCm39) |
|
probably benign |
Het |
| Pmpcb |
G |
A |
5: 21,947,944 (GRCm39) |
E216K |
probably benign |
Het |
| Pskh1 |
G |
A |
8: 106,639,731 (GRCm39) |
R137Q |
possibly damaging |
Het |
| Ptprb |
T |
G |
10: 116,184,071 (GRCm39) |
W1628G |
probably benign |
Het |
| Ranbp3 |
T |
A |
17: 57,014,955 (GRCm39) |
|
probably null |
Het |
| Sart1 |
T |
C |
19: 5,433,823 (GRCm39) |
D338G |
probably damaging |
Het |
| Scn8a |
T |
A |
15: 100,870,703 (GRCm39) |
Y251* |
probably null |
Het |
| Sdk2 |
G |
T |
11: 113,720,885 (GRCm39) |
T1348K |
probably benign |
Het |
| Sec16a |
A |
G |
2: 26,323,379 (GRCm39) |
Y1272H |
probably damaging |
Het |
| Slc26a1 |
A |
T |
5: 108,819,903 (GRCm39) |
L432Q |
probably damaging |
Het |
| Susd1 |
A |
T |
4: 59,412,203 (GRCm39) |
F117I |
possibly damaging |
Het |
| Taf5 |
A |
T |
19: 47,064,549 (GRCm39) |
Y465F |
probably damaging |
Het |
| Tcstv1a |
T |
A |
13: 120,355,630 (GRCm39) |
M1L |
probably benign |
Het |
| Tectb |
A |
G |
19: 55,178,058 (GRCm39) |
D193G |
possibly damaging |
Het |
| Tex56 |
T |
G |
13: 35,116,429 (GRCm39) |
C59W |
probably damaging |
Het |
| Tirap |
G |
A |
9: 35,100,465 (GRCm39) |
P73L |
probably damaging |
Het |
| Tm6sf2 |
A |
G |
8: 70,528,039 (GRCm39) |
D86G |
possibly damaging |
Het |
| Tmem161b |
A |
T |
13: 84,442,977 (GRCm39) |
H481L |
probably damaging |
Het |
| Tnrc6c |
G |
A |
11: 117,650,534 (GRCm39) |
V1763I |
probably damaging |
Het |
| Ubxn1 |
T |
C |
19: 8,849,584 (GRCm39) |
S75P |
probably benign |
Het |
| Uhrf2 |
A |
G |
19: 30,066,702 (GRCm39) |
K709E |
probably damaging |
Het |
| Vmn2r101 |
T |
A |
17: 19,809,092 (GRCm39) |
Y74N |
probably damaging |
Het |
| Xirp2 |
A |
G |
2: 67,335,424 (GRCm39) |
E81G |
probably benign |
Het |
| Zbtb45 |
A |
G |
7: 12,742,237 (GRCm39) |
V7A |
possibly damaging |
Het |
| Zfp668 |
C |
A |
7: 127,465,474 (GRCm39) |
R570L |
possibly damaging |
Het |
| Zmiz1 |
T |
A |
14: 25,636,390 (GRCm39) |
M125K |
possibly damaging |
Het |
| Zmiz2 |
T |
C |
11: 6,355,072 (GRCm39) |
L913P |
probably damaging |
Het |
|
| Other mutations in Abcc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:Abcc1
|
APN |
16 |
14,278,847 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL00094:Abcc1
|
APN |
16 |
14,288,398 (GRCm39) |
missense |
probably null |
0.00 |
|
IGL00475:Abcc1
|
APN |
16 |
14,254,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00516:Abcc1
|
APN |
16 |
14,231,176 (GRCm39) |
nonsense |
probably null |
|
|
IGL00765:Abcc1
|
APN |
16 |
14,229,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00792:Abcc1
|
APN |
16 |
14,228,790 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL01678:Abcc1
|
APN |
16 |
14,222,883 (GRCm39) |
missense |
probably null |
0.96 |
|
IGL01683:Abcc1
|
APN |
16 |
14,214,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01955:Abcc1
|
APN |
16 |
14,228,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02048:Abcc1
|
APN |
16 |
14,229,383 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02345:Abcc1
|
APN |
16 |
14,214,215 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02366:Abcc1
|
APN |
16 |
14,285,843 (GRCm39) |
splice site |
probably benign |
|
|
IGL02431:Abcc1
|
APN |
16 |
14,237,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02480:Abcc1
|
APN |
16 |
14,221,869 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02651:Abcc1
|
APN |
16 |
14,283,990 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02902:Abcc1
|
APN |
16 |
14,240,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03101:Abcc1
|
APN |
16 |
14,207,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03230:Abcc1
|
APN |
16 |
14,275,811 (GRCm39) |
missense |
probably benign |
|
|
IGL03308:Abcc1
|
APN |
16 |
14,288,475 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
gloom
|
UTSW |
16 |
14,229,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
loom
|
UTSW |
16 |
14,290,794 (GRCm39) |
missense |
probably damaging |
0.96 |
|
PIT4544001:Abcc1
|
UTSW |
16 |
14,222,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0310:Abcc1
|
UTSW |
16 |
14,228,791 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0594:Abcc1
|
UTSW |
16 |
14,207,744 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0894:Abcc1
|
UTSW |
16 |
14,283,001 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0928:Abcc1
|
UTSW |
16 |
14,207,849 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1367:Abcc1
|
UTSW |
16 |
14,261,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1496:Abcc1
|
UTSW |
16 |
14,266,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1643:Abcc1
|
UTSW |
16 |
14,231,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1795:Abcc1
|
UTSW |
16 |
14,283,001 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1834:Abcc1
|
UTSW |
16 |
14,240,981 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1847:Abcc1
|
UTSW |
16 |
14,263,313 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1959:Abcc1
|
UTSW |
16 |
14,214,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1961:Abcc1
|
UTSW |
16 |
14,214,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2017:Abcc1
|
UTSW |
16 |
14,279,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2224:Abcc1
|
UTSW |
16 |
14,289,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2377:Abcc1
|
UTSW |
16 |
14,285,787 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2513:Abcc1
|
UTSW |
16 |
14,290,873 (GRCm39) |
splice site |
probably null |
|
|
R2876:Abcc1
|
UTSW |
16 |
14,275,824 (GRCm39) |
missense |
probably benign |
|
|
R3003:Abcc1
|
UTSW |
16 |
14,254,393 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3941:Abcc1
|
UTSW |
16 |
14,214,263 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4119:Abcc1
|
UTSW |
16 |
14,211,877 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4191:Abcc1
|
UTSW |
16 |
14,207,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4369:Abcc1
|
UTSW |
16 |
14,278,857 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4428:Abcc1
|
UTSW |
16 |
14,263,164 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4589:Abcc1
|
UTSW |
16 |
14,211,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4779:Abcc1
|
UTSW |
16 |
14,228,635 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5027:Abcc1
|
UTSW |
16 |
14,221,917 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5275:Abcc1
|
UTSW |
16 |
14,284,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5418:Abcc1
|
UTSW |
16 |
14,278,996 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5490:Abcc1
|
UTSW |
16 |
14,228,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5527:Abcc1
|
UTSW |
16 |
14,278,842 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5641:Abcc1
|
UTSW |
16 |
14,289,877 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5642:Abcc1
|
UTSW |
16 |
14,261,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5916:Abcc1
|
UTSW |
16 |
14,283,006 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6112:Abcc1
|
UTSW |
16 |
14,278,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6331:Abcc1
|
UTSW |
16 |
14,282,920 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6464:Abcc1
|
UTSW |
16 |
14,265,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6950:Abcc1
|
UTSW |
16 |
14,229,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7024:Abcc1
|
UTSW |
16 |
14,231,247 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7115:Abcc1
|
UTSW |
16 |
14,255,589 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7187:Abcc1
|
UTSW |
16 |
14,284,861 (GRCm39) |
missense |
probably benign |
|
|
R7298:Abcc1
|
UTSW |
16 |
14,214,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7342:Abcc1
|
UTSW |
16 |
14,283,033 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7474:Abcc1
|
UTSW |
16 |
14,290,850 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7488:Abcc1
|
UTSW |
16 |
14,207,763 (GRCm39) |
nonsense |
probably null |
|
|
R7583:Abcc1
|
UTSW |
16 |
14,221,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7619:Abcc1
|
UTSW |
16 |
14,263,283 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7971:Abcc1
|
UTSW |
16 |
14,266,443 (GRCm39) |
missense |
probably benign |
|
|
R8048:Abcc1
|
UTSW |
16 |
14,228,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8138:Abcc1
|
UTSW |
16 |
14,290,751 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8159:Abcc1
|
UTSW |
16 |
14,290,794 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8319:Abcc1
|
UTSW |
16 |
14,214,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8859:Abcc1
|
UTSW |
16 |
14,214,225 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8980:Abcc1
|
UTSW |
16 |
14,278,961 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9480:Abcc1
|
UTSW |
16 |
14,211,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9519:Abcc1
|
UTSW |
16 |
14,207,681 (GRCm39) |
missense |
probably benign |
|
|
R9653:Abcc1
|
UTSW |
16 |
14,214,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9708:Abcc1
|
UTSW |
16 |
14,254,417 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9725:Abcc1
|
UTSW |
16 |
14,290,797 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9786:Abcc1
|
UTSW |
16 |
14,222,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Abcc1
|
UTSW |
16 |
14,277,766 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Z1088:Abcc1
|
UTSW |
16 |
14,228,673 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Abcc1
|
UTSW |
16 |
14,229,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCGTGTGGACCATGTGTCAC -3'
(R):5'- CAATCCCAAGAGGTCCTGGAAG -3'
Sequencing Primer
(F):5'- ACCATGTGTCACCTTGGAAG -3'
(R):5'- AGGCACTTAGCTCACCCTC -3'
|
| Posted On |
2017-02-10 |
Incidental Mutation