Incidental Mutation 'R5890:Zfp236'
| ID |
457133 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp236
|
| Ensembl Gene |
ENSMUSG00000041258 |
| Gene Name |
zinc finger protein 236 |
| Synonyms |
LOC240456 |
| MMRRC Submission |
044091-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R5890 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
82611718-82711008 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 82658276 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Serine
at position 614
(F614S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130004
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000171071]
[ENSMUST00000182122]
[ENSMUST00000183048]
|
| AlphaFold |
S4R299 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000171071
AA Change: F614S
PolyPhen 2
Score 0.873 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000130004
Gene: ENSMUSG00000041258
AA Change: F614S
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
low complexity region
|
290 |
309 |
N/A |
INTRINSIC |
|
low complexity region
|
403 |
426 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
436 |
458 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
464 |
486 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
492 |
514 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
520 |
542 |
1.18e-2 |
SMART |
|
low complexity region
|
592 |
605 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
611 |
633 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
639 |
661 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
667 |
689 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
695 |
717 |
7.37e-4 |
SMART |
|
low complexity region
|
720 |
733 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
922 |
944 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
950 |
972 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
978 |
1000 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1006 |
1028 |
2.75e-3 |
SMART |
|
low complexity region
|
1030 |
1039 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1122 |
1144 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1150 |
1172 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1178 |
1200 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1206 |
1228 |
5.42e-2 |
SMART |
|
low complexity region
|
1243 |
1258 |
N/A |
INTRINSIC |
|
low complexity region
|
1462 |
1477 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1612 |
1635 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1641 |
1663 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1677 |
1699 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1705 |
1727 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1733 |
1756 |
2.95e-3 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000182122
AA Change: F662S
PolyPhen 2
Score 0.679 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000138557
Gene: ENSMUSG00000041258
AA Change: F662S
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
474 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
484 |
506 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
512 |
534 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
540 |
562 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
568 |
590 |
1.18e-2 |
SMART |
|
low complexity region
|
640 |
653 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
659 |
681 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
687 |
709 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
715 |
737 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
743 |
765 |
7.37e-4 |
SMART |
|
low complexity region
|
768 |
781 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
970 |
992 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
998 |
1020 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
1026 |
1048 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1054 |
1076 |
2.75e-3 |
SMART |
|
low complexity region
|
1078 |
1087 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1170 |
1192 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1198 |
1220 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1226 |
1248 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1254 |
1276 |
5.42e-2 |
SMART |
|
low complexity region
|
1291 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1510 |
1525 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1660 |
1683 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1689 |
1711 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1725 |
1747 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1753 |
1775 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1781 |
1804 |
2.95e-3 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182759
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183048
|
| SMART Domains |
Protein: ENSMUSP00000138179
Gene: ENSMUSG00000041258
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
467 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.5%
- 10x: 97.6%
- 20x: 92.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 68 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc9 |
A |
G |
6: 142,550,554 (GRCm39) |
|
probably null |
Het |
| Acsm3 |
C |
A |
7: 119,374,457 (GRCm39) |
T303N |
probably benign |
Het |
| Adamts13 |
A |
T |
2: 26,876,603 (GRCm39) |
R506W |
probably damaging |
Het |
| Adck5 |
C |
T |
15: 76,477,785 (GRCm39) |
T166M |
probably damaging |
Het |
| Adcy8 |
T |
A |
15: 64,687,266 (GRCm39) |
I413F |
probably damaging |
Het |
| Adgrl2 |
A |
T |
3: 148,564,811 (GRCm39) |
D252E |
probably damaging |
Het |
| Aldh16a1 |
T |
A |
7: 44,793,969 (GRCm39) |
T636S |
probably benign |
Het |
| Ampd1 |
C |
A |
3: 102,997,391 (GRCm39) |
F264L |
probably damaging |
Het |
| Arhgap17 |
T |
C |
7: 122,885,981 (GRCm39) |
|
probably benign |
Het |
| Babam2 |
A |
G |
5: 32,222,151 (GRCm39) |
|
probably benign |
Het |
| Bltp2 |
C |
T |
11: 78,164,096 (GRCm39) |
Q40* |
probably null |
Het |
| Bod1l |
T |
A |
5: 41,977,921 (GRCm39) |
E1131V |
probably benign |
Het |
| Cbs |
C |
T |
17: 31,832,193 (GRCm39) |
V553M |
probably damaging |
Het |
| Cd72 |
T |
C |
4: 43,454,475 (GRCm39) |
K18R |
probably damaging |
Het |
| Cep89 |
A |
G |
7: 35,128,587 (GRCm39) |
Y580C |
probably damaging |
Het |
| Chrnb1 |
T |
A |
11: 69,683,555 (GRCm39) |
I264F |
possibly damaging |
Het |
| Cntf |
A |
G |
19: 12,741,357 (GRCm39) |
W168R |
probably damaging |
Het |
| Cxxc1 |
T |
A |
18: 74,354,237 (GRCm39) |
D648E |
possibly damaging |
Het |
| Cyp2c68 |
A |
T |
19: 39,700,936 (GRCm39) |
L294Q |
probably damaging |
Het |
| Dab2ip |
T |
C |
2: 35,605,414 (GRCm39) |
S532P |
probably damaging |
Het |
| Defb3 |
G |
A |
8: 19,345,200 (GRCm39) |
C52Y |
probably damaging |
Het |
| Dennd5a |
T |
G |
7: 109,533,428 (GRCm39) |
E114A |
probably benign |
Het |
| Dnah12 |
T |
C |
14: 26,428,039 (GRCm39) |
F222L |
probably benign |
Het |
| Dock9 |
A |
C |
14: 121,905,820 (GRCm39) |
|
probably null |
Het |
| Fras1 |
A |
T |
5: 96,793,807 (GRCm39) |
H1043L |
probably benign |
Het |
| Gamt |
C |
A |
10: 80,095,741 (GRCm39) |
R63L |
possibly damaging |
Het |
| Gm1527 |
A |
G |
3: 28,969,544 (GRCm39) |
H298R |
probably benign |
Het |
| Gphb5 |
C |
T |
12: 75,462,596 (GRCm39) |
|
probably null |
Het |
| Greb1 |
A |
T |
12: 16,783,422 (GRCm39) |
V104D |
possibly damaging |
Het |
| Hck |
A |
G |
2: 152,970,996 (GRCm39) |
D86G |
probably damaging |
Het |
| Jhy |
T |
A |
9: 40,833,958 (GRCm39) |
K321* |
probably null |
Het |
| Kcna5 |
C |
T |
6: 126,511,699 (GRCm39) |
R143H |
probably damaging |
Het |
| Kif19a |
G |
T |
11: 114,680,264 (GRCm39) |
W867L |
possibly damaging |
Het |
| Map3k4 |
G |
A |
17: 12,490,303 (GRCm39) |
A376V |
probably damaging |
Het |
| Mars1 |
A |
T |
10: 127,133,914 (GRCm39) |
M661K |
probably benign |
Het |
| Mecp2 |
C |
T |
X: 73,079,043 (GRCm39) |
V496M |
probably damaging |
Het |
| Mfsd2b |
A |
T |
12: 4,917,651 (GRCm39) |
C132S |
probably damaging |
Het |
| Mfsd4a |
T |
C |
1: 131,966,666 (GRCm39) |
Y356C |
probably damaging |
Het |
| Mif4gd |
G |
T |
11: 115,500,188 (GRCm39) |
A89E |
probably benign |
Het |
| Mkln1 |
A |
T |
6: 31,467,482 (GRCm39) |
E593D |
probably benign |
Het |
| Mlh1 |
G |
T |
9: 111,057,563 (GRCm39) |
N749K |
possibly damaging |
Het |
| Mrgprb2 |
T |
A |
7: 48,201,707 (GRCm39) |
*339C |
probably null |
Het |
| Nphp4 |
T |
C |
4: 152,631,536 (GRCm39) |
V812A |
probably benign |
Het |
| Nrcam |
G |
T |
12: 44,623,554 (GRCm39) |
V1048L |
probably benign |
Het |
| Obsl1 |
G |
A |
1: 75,470,503 (GRCm39) |
A856V |
probably damaging |
Het |
| Osgepl1 |
T |
A |
1: 53,357,326 (GRCm39) |
F163I |
probably damaging |
Het |
| Pcdha6 |
C |
A |
18: 37,102,121 (GRCm39) |
T438K |
possibly damaging |
Het |
| Pcdhb20 |
A |
T |
18: 37,638,286 (GRCm39) |
M271L |
probably benign |
Het |
| Phip |
T |
C |
9: 82,789,005 (GRCm39) |
T770A |
probably benign |
Het |
| Ppm1d |
A |
G |
11: 85,217,734 (GRCm39) |
T166A |
probably damaging |
Het |
| Ptprf |
A |
T |
4: 118,081,932 (GRCm39) |
I1102K |
probably benign |
Het |
| Sbsn |
T |
C |
7: 30,452,692 (GRCm39) |
V569A |
possibly damaging |
Het |
| Skida1 |
T |
A |
2: 18,050,814 (GRCm39) |
|
probably benign |
Het |
| Smg1 |
T |
A |
7: 117,789,809 (GRCm39) |
|
probably benign |
Het |
| Sorcs2 |
A |
G |
5: 36,386,535 (GRCm39) |
Y168H |
probably damaging |
Het |
| Sufu |
A |
T |
19: 46,443,172 (GRCm39) |
|
probably null |
Het |
| Tbc1d24 |
A |
T |
17: 24,404,500 (GRCm39) |
W215R |
probably damaging |
Het |
| Tenm4 |
T |
C |
7: 96,552,067 (GRCm39) |
L2502P |
probably damaging |
Het |
| Tgm4 |
A |
T |
9: 122,890,703 (GRCm39) |
E10V |
probably damaging |
Het |
| Trip11 |
T |
C |
12: 101,852,231 (GRCm39) |
E611G |
probably damaging |
Het |
| Ttn |
C |
A |
2: 76,540,243 (GRCm39) |
A34248S |
possibly damaging |
Het |
| Ube3a |
T |
A |
7: 58,921,776 (GRCm39) |
N49K |
probably damaging |
Het |
| Ube3c |
A |
G |
5: 29,863,290 (GRCm39) |
D855G |
possibly damaging |
Het |
| Ugt8a |
A |
G |
3: 125,669,202 (GRCm39) |
S301P |
probably benign |
Het |
| Wdfy4 |
T |
A |
14: 32,824,534 (GRCm39) |
N1295I |
possibly damaging |
Het |
| Wdr47 |
G |
T |
3: 108,517,328 (GRCm39) |
G43C |
probably damaging |
Het |
| Wdtc1 |
A |
C |
4: 133,021,673 (GRCm39) |
L601W |
unknown |
Het |
| Zfp637 |
T |
A |
6: 117,822,047 (GRCm39) |
D58E |
possibly damaging |
Het |
|
| Other mutations in Zfp236 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Zfp236
|
APN |
18 |
82,686,815 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01760:Zfp236
|
APN |
18 |
82,639,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01923:Zfp236
|
APN |
18 |
82,700,344 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01934:Zfp236
|
APN |
18 |
82,651,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01949:Zfp236
|
APN |
18 |
82,642,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02063:Zfp236
|
APN |
18 |
82,676,276 (GRCm39) |
missense |
probably benign |
|
|
IGL02496:Zfp236
|
APN |
18 |
82,648,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02513:Zfp236
|
APN |
18 |
82,648,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Zfp236
|
APN |
18 |
82,676,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL02880:Zfp236
|
APN |
18 |
82,642,584 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL03156:Zfp236
|
APN |
18 |
82,698,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03261:Zfp236
|
APN |
18 |
82,648,733 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0047:Zfp236
|
UTSW |
18 |
82,698,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0052:Zfp236
|
UTSW |
18 |
82,657,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0194:Zfp236
|
UTSW |
18 |
82,675,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0207:Zfp236
|
UTSW |
18 |
82,658,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0302:Zfp236
|
UTSW |
18 |
82,676,213 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0730:Zfp236
|
UTSW |
18 |
82,658,369 (GRCm39) |
splice site |
probably benign |
|
|
R0755:Zfp236
|
UTSW |
18 |
82,638,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1202:Zfp236
|
UTSW |
18 |
82,646,291 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1449:Zfp236
|
UTSW |
18 |
82,664,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1550:Zfp236
|
UTSW |
18 |
82,692,549 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1785:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1786:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2042:Zfp236
|
UTSW |
18 |
82,651,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2133:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2247:Zfp236
|
UTSW |
18 |
82,622,423 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2484:Zfp236
|
UTSW |
18 |
82,686,762 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3715:Zfp236
|
UTSW |
18 |
82,651,095 (GRCm39) |
splice site |
probably benign |
|
|
R4003:Zfp236
|
UTSW |
18 |
82,698,870 (GRCm39) |
nonsense |
probably null |
|
|
R4031:Zfp236
|
UTSW |
18 |
82,642,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4482:Zfp236
|
UTSW |
18 |
82,662,346 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4492:Zfp236
|
UTSW |
18 |
82,648,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4502:Zfp236
|
UTSW |
18 |
82,655,079 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4561:Zfp236
|
UTSW |
18 |
82,638,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4649:Zfp236
|
UTSW |
18 |
82,615,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Zfp236
|
UTSW |
18 |
82,627,543 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5064:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5084:Zfp236
|
UTSW |
18 |
82,627,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5090:Zfp236
|
UTSW |
18 |
82,637,006 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5191:Zfp236
|
UTSW |
18 |
82,639,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5264:Zfp236
|
UTSW |
18 |
82,676,198 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5264:Zfp236
|
UTSW |
18 |
82,648,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5339:Zfp236
|
UTSW |
18 |
82,642,491 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5375:Zfp236
|
UTSW |
18 |
82,615,813 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5445:Zfp236
|
UTSW |
18 |
82,700,281 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5513:Zfp236
|
UTSW |
18 |
82,676,147 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5527:Zfp236
|
UTSW |
18 |
82,676,159 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5628:Zfp236
|
UTSW |
18 |
82,675,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5758:Zfp236
|
UTSW |
18 |
82,689,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6137:Zfp236
|
UTSW |
18 |
82,689,919 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6193:Zfp236
|
UTSW |
18 |
82,622,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6198:Zfp236
|
UTSW |
18 |
82,675,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Zfp236
|
UTSW |
18 |
82,675,229 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6705:Zfp236
|
UTSW |
18 |
82,651,862 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6948:Zfp236
|
UTSW |
18 |
82,662,187 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6989:Zfp236
|
UTSW |
18 |
82,646,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7002:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7113:Zfp236
|
UTSW |
18 |
82,638,462 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7261:Zfp236
|
UTSW |
18 |
82,627,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7363:Zfp236
|
UTSW |
18 |
82,639,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7447:Zfp236
|
UTSW |
18 |
82,651,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7564:Zfp236
|
UTSW |
18 |
82,662,366 (GRCm39) |
nonsense |
probably null |
|
|
R7731:Zfp236
|
UTSW |
18 |
82,698,798 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7857:Zfp236
|
UTSW |
18 |
82,686,726 (GRCm39) |
nonsense |
probably null |
|
|
R7860:Zfp236
|
UTSW |
18 |
82,692,481 (GRCm39) |
nonsense |
probably null |
|
|
R7904:Zfp236
|
UTSW |
18 |
82,627,507 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7948:Zfp236
|
UTSW |
18 |
82,642,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Zfp236
|
UTSW |
18 |
82,657,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Zfp236
|
UTSW |
18 |
82,648,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8435:Zfp236
|
UTSW |
18 |
82,658,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Zfp236
|
UTSW |
18 |
82,664,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8878:Zfp236
|
UTSW |
18 |
82,617,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Zfp236
|
UTSW |
18 |
82,664,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9046:Zfp236
|
UTSW |
18 |
82,637,042 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9076:Zfp236
|
UTSW |
18 |
82,638,469 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9243:Zfp236
|
UTSW |
18 |
82,662,050 (GRCm39) |
intron |
probably benign |
|
|
R9594:Zfp236
|
UTSW |
18 |
82,664,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9642:Zfp236
|
UTSW |
18 |
82,622,384 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9707:Zfp236
|
UTSW |
18 |
82,664,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9748:Zfp236
|
UTSW |
18 |
82,637,008 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGGTCTTTGACACATGCTAGAAATTG -3'
(R):5'- TCACGCAATGCCTTTGACATG -3'
Sequencing Primer
(F):5'- GACACATGCTAGAAATTGCAAATAC -3'
(R):5'- CGCAATGCCTTTGACATGTTAGTAG -3'
|
| Posted On |
2017-02-15 |
Incidental Mutation