Mutagenetix > Incidental Mutation

Incidental Mutation 'R5719:Ptprd'

458120

Institutional Source

Beutler Lab

Gene Symbol

Ptprd

Ensembl Gene

ENSMUSG00000028399

Gene Name

protein tyrosine phosphatase receptor type D

Synonyms

1110002J03Rik, B230219D21Rik, 3000002J10Rik

MMRRC Submission

043339-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R5719 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

75859475-78130198 bp(-) (GRCm39)

Type of Mutation

critical splice acceptor site

DNA Base Change (assembly)

T to A at 75972839 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000148560 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000050757] [ENSMUST00000098005] [ENSMUST00000102834] [ENSMUST00000107289] [ENSMUST00000173376] [ENSMUST00000174023] [ENSMUST00000174180] [ENSMUST00000174831] [ENSMUST00000212365] [ENSMUST00000174531]

AlphaFold

Q64487

Predicted Effect

probably benign
Transcript: ENSMUST00000050757

SMART Domains

Protein: ENSMUSP00000058466
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	208	1.38e-15	SMART
IGc2	238	299	8.13e-4	SMART
FN3	313	392	7.92e-14	SMART
FN3	408	491	5.73e-11	SMART
IG_like	499	593	8.34e1	SMART
FN3	506	584	9.1e-14	SMART
FN3	597	674	1.21e0	SMART
transmembrane domain	847	869	N/A	INTRINSIC
low complexity region	870	882	N/A	INTRINSIC
PTPc	949	1207	6.38e-134	SMART
PTPc	1236	1498	9.17e-135	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000098005
AA Change: S882C

PolyPhen 2 Score 0.420 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000095614
Gene: ENSMUSG00000028399
AA Change: S882C

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	214	8.5e-16	SMART
low complexity region	225	237	N/A	INTRINSIC
IGc2	248	309	8.13e-4	SMART
FN3	323	402	7.92e-14	SMART
FN3	418	501	5.73e-11	SMART
IG_like	509	603	8.34e1	SMART
FN3	516	594	9.1e-14	SMART
FN3	607	684	1.21e0	SMART
transmembrane domain	857	879	N/A	INTRINSIC
low complexity region	886	897	N/A	INTRINSIC
PTPc	950	1208	6.38e-134	SMART
PTPc	1237	1499	9.17e-135	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000102834

SMART Domains

Protein: ENSMUSP00000099898
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	1	62	8.13e-4	SMART
FN3	76	155	7.92e-14	SMART
FN3	171	254	5.73e-11	SMART
IG_like	262	356	8.34e1	SMART
FN3	269	347	9.1e-14	SMART
FN3	360	437	1.21e0	SMART
transmembrane domain	610	632	N/A	INTRINSIC
low complexity region	633	645	N/A	INTRINSIC
PTPc	698	956	6.38e-134	SMART
PTPc	985	1247	9.17e-135	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000107289

SMART Domains

Protein: ENSMUSP00000102910
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	214	8.5e-16	SMART
low complexity region	225	237	N/A	INTRINSIC
IGc2	248	309	8.13e-4	SMART
FN3	323	402	7.92e-14	SMART
FN3	418	501	5.73e-11	SMART
IG_like	509	603	8.34e1	SMART
FN3	516	594	9.1e-14	SMART
FN3	609	696	2.72e-12	SMART
FN3	712	809	2.87e-11	SMART
FN3	824	904	4.96e-6	SMART
FN3	919	1003	4.12e-12	SMART
FN3	1018	1095	1.95e0	SMART
transmembrane domain	1268	1290	N/A	INTRINSIC
low complexity region	1291	1303	N/A	INTRINSIC
PTPc	1356	1614	6.38e-134	SMART
PTPc	1643	1905	9.17e-135	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000173376

SMART Domains

Protein: ENSMUSP00000133468
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	43	112	8.57e-12	SMART
IGc2	145	221	8.5e-16	SMART
low complexity region	232	244	N/A	INTRINSIC
IGc2	255	316	8.13e-4	SMART
FN3	330	409	7.92e-14	SMART
FN3	425	508	5.73e-11	SMART
IG_like	516	610	8.34e1	SMART
FN3	523	601	9.1e-14	SMART
FN3	614	691	1.21e0	SMART
transmembrane domain	864	886	N/A	INTRINSIC
low complexity region	887	899	N/A	INTRINSIC
PTPc	952	1210	6.38e-134	SMART
PTPc	1239	1501	9.17e-135	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000174023

SMART Domains

Protein: ENSMUSP00000133562
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	211	4.88e-16	SMART
low complexity region	222	234	N/A	INTRINSIC
IGc2	245	306	8.13e-4	SMART
FN3	320	399	7.92e-14	SMART
FN3	415	498	5.73e-11	SMART
IG_like	506	600	8.34e1	SMART
FN3	513	591	9.1e-14	SMART
FN3	604	681	1.21e0	SMART
transmembrane domain	853	875	N/A	INTRINSIC
low complexity region	882	893	N/A	INTRINSIC
PTPc	946	1204	6.38e-134	SMART
PTPc	1233	1495	9.17e-135	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000174180

SMART Domains

Protein: ENSMUSP00000133973
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	205	2.09e-15	SMART
IGc2	235	296	8.13e-4	SMART
FN3	310	389	7.92e-14	SMART
FN3	405	488	5.73e-11	SMART
IG_like	496	590	8.34e1	SMART
FN3	503	581	9.1e-14	SMART
FN3	596	683	2.72e-12	SMART
FN3	699	787	6.15e-11	SMART
FN3	802	882	4.96e-6	SMART
FN3	897	981	4.12e-12	SMART
FN3	996	1073	1.95e0	SMART
transmembrane domain	1246	1268	N/A	INTRINSIC
low complexity region	1269	1281	N/A	INTRINSIC
PTPc	1334	1592	6.38e-134	SMART
PTPc	1621	1883	9.17e-135	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000174831

SMART Domains

Protein: ENSMUSP00000133328
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	214	8.5e-16	SMART
low complexity region	225	237	N/A	INTRINSIC
IGc2	248	309	8.13e-4	SMART
FN3	323	402	7.92e-14	SMART
FN3	418	501	5.73e-11	SMART
IG_like	509	603	8.34e1	SMART
FN3	516	594	9.1e-14	SMART
FN3	607	684	1.21e0	SMART
transmembrane domain	856	878	N/A	INTRINSIC
low complexity region	885	896	N/A	INTRINSIC
PTPc	949	1207	6.38e-134	SMART
PTPc	1236	1498	9.17e-135	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000212365

Predicted Effect

probably benign
Transcript: ENSMUST00000174531

SMART Domains

Protein: ENSMUSP00000134229
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	208	1.38e-15	SMART
low complexity region	219	231	N/A	INTRINSIC
IGc2	242	303	8.13e-4	SMART
FN3	317	396	7.92e-14	SMART
FN3	412	495	5.73e-11	SMART
IG_like	503	597	8.34e1	SMART
FN3	510	588	9.1e-14	SMART
FN3	601	678	1.21e0	SMART
transmembrane domain	851	873	N/A	INTRINSIC
low complexity region	874	886	N/A	INTRINSIC
PTPc	939	1197	6.38e-134	SMART
PTPc	1226	1488	9.17e-135	SMART

Meta Mutation Damage Score

0.9709

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.3%

Validation Efficiency

98% (79/81)

MGI Phenotype

PHENOTYPE: Homozygotes for a targeted null mutation exhibit impaired learning of spatial tasks, enhanced long-term potentiation at hippocampal synapses, and high mortality associated with reduced food intake. [provided by MGI curators]

Allele List at MGI

All alleles(9) : Targeted(4) Gene trapped(5)

Other mutations in this stock

Total: 69 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A130051J06Rik	C	T	15: 95,688,641 (GRCm39)		probably benign	Het
A630001G21Rik	T	A	1: 85,651,106 (GRCm39)	R110W	probably benign	Het
Abca4	T	C	3: 121,928,915 (GRCm39)		probably null	Het
Abcc3	T	C	11: 94,241,894 (GRCm39)	N1379S	probably damaging	Het
Actrt3	A	C	3: 30,652,276 (GRCm39)	F273V	probably benign	Het
Adam22	T	C	5: 8,417,217 (GRCm39)	D75G	probably benign	Het
Ash1l	C	A	3: 88,961,805 (GRCm39)	D2392E	possibly damaging	Het
Ash1l	T	C	3: 88,965,933 (GRCm39)	I2445T	probably damaging	Het
Bltp2	T	A	11: 78,164,071 (GRCm39)	H1137Q	probably damaging	Het
Cacna2d2	A	G	9: 107,401,851 (GRCm39)	I762V	probably benign	Het
Ccdc127	T	A	13: 74,505,187 (GRCm39)		probably benign	Het
Ccdc91	C	G	6: 147,477,001 (GRCm39)	L230V	unknown	Het
Cdk13	A	G	13: 17,894,240 (GRCm39)	I1129T	probably damaging	Het
Cnot1	C	T	8: 96,470,924 (GRCm39)	R1308H	possibly damaging	Het
Crhr2	T	C	6: 55,080,207 (GRCm39)	H144R	probably damaging	Het
Dnmt1	T	C	9: 20,823,891 (GRCm39)	N993S	possibly damaging	Het
Eif4g1	T	A	16: 20,507,761 (GRCm39)	V1182D	probably damaging	Het
Eml2	G	A	7: 18,935,088 (GRCm39)	V432I	probably damaging	Het
Fam234a	T	A	17: 26,433,627 (GRCm39)	Q399L	possibly damaging	Het
Fyb1	A	T	15: 6,610,350 (GRCm39)	K308*	probably null	Het
Gfral	C	T	9: 76,104,328 (GRCm39)	R228Q	probably benign	Het
Gm10309	A	T	17: 86,806,421 (GRCm39)		probably benign	Het
Gm11595	G	A	11: 99,663,381 (GRCm39)	R100C	unknown	Het
Gm5501	G	A	18: 9,917,417 (GRCm39)		noncoding transcript	Het
Gm6309	A	T	5: 146,104,992 (GRCm39)	V307D	probably benign	Het
Gm9871	T	A	6: 101,773,148 (GRCm39)		noncoding transcript	Het
Greb1l	G	A	18: 10,542,427 (GRCm39)	E1341K	probably damaging	Het
Herc3	T	A	6: 58,871,528 (GRCm39)	V70E	possibly damaging	Het
Hes7	A	G	11: 69,012,415 (GRCm39)	E41G	probably damaging	Het
Ifi27l2b	T	C	12: 103,422,046 (GRCm39)	D106G	unknown	Het
Igfbp6	A	T	15: 102,056,616 (GRCm39)	Y184F	probably damaging	Het
Isyna1	A	G	8: 71,047,352 (GRCm39)	Y25C	probably damaging	Het
Kcng3	G	T	17: 83,938,563 (GRCm39)	T162K	possibly damaging	Het
Krt36	T	C	11: 99,994,987 (GRCm39)	D195G	possibly damaging	Het
Lrwd1	A	T	5: 136,161,093 (GRCm39)		probably null	Het
Lsg1	C	T	16: 30,380,593 (GRCm39)	A615T	probably benign	Het
Myo5a	A	T	9: 75,059,213 (GRCm39)	E480D	probably damaging	Het
Myrf	T	A	19: 10,194,087 (GRCm39)	D690V	probably damaging	Het
N4bp1	T	C	8: 87,578,312 (GRCm39)	I684M	probably damaging	Het
Nlrc3	C	T	16: 3,781,589 (GRCm39)	A607T	probably damaging	Het
Nuak1	A	T	10: 84,245,584 (GRCm39)	I87N	probably damaging	Het
Odad2	G	T	18: 7,211,496 (GRCm39)	Q793K	probably benign	Het
Or5p66	T	G	7: 107,885,599 (GRCm39)	T245P	probably damaging	Het
Or5w11	T	C	2: 87,459,475 (GRCm39)		probably null	Het
Or8b4	A	T	9: 37,830,647 (GRCm39)	E236D	probably damaging	Het
Osbpl9	T	A	4: 108,919,763 (GRCm39)	R689*	probably null	Het
Ppargc1b	T	A	18: 61,440,639 (GRCm39)	M744L	probably benign	Het
Prss40	A	T	1: 34,591,598 (GRCm39)		probably benign	Het
Rft1	T	C	14: 30,385,183 (GRCm39)		probably benign	Het
Rftn2	C	T	1: 55,253,445 (GRCm39)	V53I	probably damaging	Het
Rnaset2a	T	C	17: 8,350,879 (GRCm39)	Y167C	probably damaging	Het
Schip1	T	C	3: 68,315,560 (GRCm39)		probably benign	Het
Scn5a	A	C	9: 119,359,118 (GRCm39)	L643R	possibly damaging	Het
Shroom3	T	A	5: 93,090,877 (GRCm39)	M1128K	probably benign	Het
Skint8	C	A	4: 111,807,390 (GRCm39)	L359M	probably damaging	Het
Slc14a2	A	G	18: 78,252,257 (GRCm39)	L18P	probably benign	Het
Slc22a3	C	T	17: 12,642,691 (GRCm39)	V509M	probably damaging	Het
Slc7a5	A	C	8: 122,610,381 (GRCm39)	F478V	probably benign	Het
Smc1b	T	A	15: 84,980,859 (GRCm39)	N803I	probably benign	Het
Snf8	T	A	11: 95,932,551 (GRCm39)	N115K	probably damaging	Het
Stox2	T	A	8: 47,866,172 (GRCm39)	K57*	probably null	Het
Tmem248	T	A	5: 130,258,429 (GRCm39)	F41I	probably damaging	Het
Tmprss7	T	C	16: 45,506,793 (GRCm39)	S90G	probably damaging	Het
Top3b	T	C	16: 16,703,700 (GRCm39)	V285A	probably damaging	Het
Tsen15	T	C	1: 152,247,534 (GRCm39)	T153A	probably damaging	Het
Usp34	T	G	11: 23,304,846 (GRCm39)	S360A	probably benign	Het
Wdr24	T	C	17: 26,047,314 (GRCm39)		probably null	Het
Zbtb2	G	A	10: 4,319,456 (GRCm39)	T190I	probably benign	Het
Zranb3	T	C	1: 127,891,613 (GRCm39)	S788G	probably benign	Het

Other mutations in Ptprd

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00964:Ptprd	APN	4	75,916,793 (GRCm39)	nonsense	probably null
IGL01067:Ptprd	APN	4	75,977,922 (GRCm39)	missense	probably damaging	1.00
IGL01121:Ptprd	APN	4	75,872,438 (GRCm39)	splice site	probably benign
IGL01531:Ptprd	APN	4	76,003,757 (GRCm39)	missense	probably damaging	0.98
IGL01661:Ptprd	APN	4	75,872,320 (GRCm39)	missense	probably damaging	1.00
IGL01723:Ptprd	APN	4	76,161,910 (GRCm39)	missense	probably damaging	1.00
IGL01735:Ptprd	APN	4	76,055,057 (GRCm39)	splice site	probably null
IGL01810:Ptprd	APN	4	76,058,744 (GRCm39)	splice site	probably benign
IGL01834:Ptprd	APN	4	76,046,832 (GRCm39)	missense	probably damaging	1.00
IGL01835:Ptprd	APN	4	76,165,058 (GRCm39)	missense	probably benign	0.02
IGL01867:Ptprd	APN	4	76,161,884 (GRCm39)	missense	probably damaging	1.00
IGL02582:Ptprd	APN	4	75,865,361 (GRCm39)	missense	probably damaging	1.00
IGL02591:Ptprd	APN	4	75,900,287 (GRCm39)	missense	probably damaging	1.00
IGL02741:Ptprd	APN	4	76,051,521 (GRCm39)	missense	probably damaging	1.00
IGL02866:Ptprd	APN	4	75,968,674 (GRCm39)	missense	probably damaging	1.00
IGL02960:Ptprd	APN	4	76,047,105 (GRCm39)	missense	probably damaging	1.00
IGL03155:Ptprd	APN	4	75,984,456 (GRCm39)	missense	possibly damaging	0.95
IGL03230:Ptprd	APN	4	75,968,654 (GRCm39)	nonsense	probably null
IGL03343:Ptprd	APN	4	75,977,966 (GRCm39)	missense	probably damaging	1.00
unhurried	UTSW	4	76,018,870 (GRCm39)	nonsense	probably null
ANU22:Ptprd	UTSW	4	76,018,693 (GRCm39)	missense	probably damaging	0.99
F5493:Ptprd	UTSW	4	76,002,645 (GRCm39)	missense	probably damaging	1.00
P0033:Ptprd	UTSW	4	76,047,091 (GRCm39)	nonsense	probably null
R0044:Ptprd	UTSW	4	76,004,566 (GRCm39)	missense	probably benign	0.08
R0044:Ptprd	UTSW	4	76,004,566 (GRCm39)	missense	probably benign	0.08
R0076:Ptprd	UTSW	4	75,865,276 (GRCm39)	splice site	probably benign
R0137:Ptprd	UTSW	4	76,055,140 (GRCm39)	missense	probably benign	0.24
R0358:Ptprd	UTSW	4	75,863,226 (GRCm39)	missense	probably damaging	1.00
R0365:Ptprd	UTSW	4	76,055,083 (GRCm39)	missense	probably damaging	1.00
R0385:Ptprd	UTSW	4	76,046,902 (GRCm39)	missense	probably damaging	1.00
R0601:Ptprd	UTSW	4	76,018,711 (GRCm39)	missense	probably benign
R0646:Ptprd	UTSW	4	76,002,640 (GRCm39)	missense	probably damaging	0.99
R0667:Ptprd	UTSW	4	75,875,583 (GRCm39)	missense	probably damaging	1.00
R0707:Ptprd	UTSW	4	75,875,476 (GRCm39)	missense	probably damaging	1.00
R0734:Ptprd	UTSW	4	76,058,834 (GRCm39)	missense	probably damaging	1.00
R0827:Ptprd	UTSW	4	76,047,152 (GRCm39)	missense	probably damaging	0.98
R0932:Ptprd	UTSW	4	76,055,122 (GRCm39)	missense	probably damaging	1.00
R1069:Ptprd	UTSW	4	76,018,870 (GRCm39)	nonsense	probably null
R1069:Ptprd	UTSW	4	75,916,724 (GRCm39)	splice site	probably benign
R1086:Ptprd	UTSW	4	76,051,495 (GRCm39)	missense	probably damaging	1.00
R1439:Ptprd	UTSW	4	75,984,437 (GRCm39)	missense	probably damaging	1.00
R1440:Ptprd	UTSW	4	76,002,789 (GRCm39)	missense	probably damaging	0.98
R1688:Ptprd	UTSW	4	75,900,921 (GRCm39)	missense	probably damaging	1.00
R1858:Ptprd	UTSW	4	75,865,384 (GRCm39)	missense	probably damaging	1.00
R2001:Ptprd	UTSW	4	75,872,359 (GRCm39)	missense	probably damaging	1.00
R2020:Ptprd	UTSW	4	76,051,398 (GRCm39)	missense	probably damaging	1.00
R2023:Ptprd	UTSW	4	75,875,341 (GRCm39)	missense	probably damaging	1.00
R2413:Ptprd	UTSW	4	76,051,437 (GRCm39)	missense	probably damaging	1.00
R2510:Ptprd	UTSW	4	76,004,248 (GRCm39)	critical splice donor site	probably null
R2914:Ptprd	UTSW	4	75,865,338 (GRCm39)	missense	probably damaging	1.00
R2971:Ptprd	UTSW	4	76,025,561 (GRCm39)	missense	probably benign	0.10
R3051:Ptprd	UTSW	4	76,018,867 (GRCm39)	missense	probably damaging	1.00
R3433:Ptprd	UTSW	4	76,004,248 (GRCm39)	critical splice donor site	probably null
R3964:Ptprd	UTSW	4	75,978,073 (GRCm39)	splice site	probably benign
R4009:Ptprd	UTSW	4	75,874,634 (GRCm39)	missense	possibly damaging	0.94
R4394:Ptprd	UTSW	4	76,046,922 (GRCm39)	missense	probably damaging	1.00
R4420:Ptprd	UTSW	4	75,957,614 (GRCm39)	missense	possibly damaging	0.92
R4424:Ptprd	UTSW	4	76,021,200 (GRCm39)	missense	probably benign	0.22
R4575:Ptprd	UTSW	4	76,162,023 (GRCm39)	missense	possibly damaging	0.55
R4578:Ptprd	UTSW	4	76,162,023 (GRCm39)	missense	possibly damaging	0.55
R4715:Ptprd	UTSW	4	76,025,570 (GRCm39)	missense	probably benign	0.03
R4782:Ptprd	UTSW	4	76,009,769 (GRCm39)	missense	probably benign	0.01
R4785:Ptprd	UTSW	4	76,058,790 (GRCm39)	missense	probably benign	0.05
R4799:Ptprd	UTSW	4	76,009,769 (GRCm39)	missense	probably benign	0.01
R4944:Ptprd	UTSW	4	76,047,136 (GRCm39)	missense	probably damaging	1.00
R4950:Ptprd	UTSW	4	76,058,752 (GRCm39)	splice site	probably null
R4969:Ptprd	UTSW	4	76,051,542 (GRCm39)	missense	probably damaging	1.00
R5153:Ptprd	UTSW	4	75,930,339 (GRCm39)	missense	probably damaging	1.00
R5164:Ptprd	UTSW	4	76,018,995 (GRCm39)	splice site	probably null
R5287:Ptprd	UTSW	4	75,872,405 (GRCm39)	nonsense	probably null
R5305:Ptprd	UTSW	4	75,900,863 (GRCm39)	missense	probably damaging	1.00
R5362:Ptprd	UTSW	4	76,047,050 (GRCm39)	missense	probably damaging	1.00
R5403:Ptprd	UTSW	4	75,872,405 (GRCm39)	nonsense	probably null
R5531:Ptprd	UTSW	4	75,977,904 (GRCm39)	critical splice donor site	probably null
R5543:Ptprd	UTSW	4	75,977,990 (GRCm39)	missense	probably damaging	1.00
R5634:Ptprd	UTSW	4	75,990,255 (GRCm39)	missense	probably benign	0.01
R5884:Ptprd	UTSW	4	75,900,927 (GRCm39)	missense	probably damaging	1.00
R6247:Ptprd	UTSW	4	75,984,528 (GRCm39)	missense	probably benign	0.06
R6250:Ptprd	UTSW	4	76,047,232 (GRCm39)	missense	probably damaging	1.00
R6335:Ptprd	UTSW	4	75,872,420 (GRCm39)	missense	probably damaging	1.00
R6352:Ptprd	UTSW	4	76,009,789 (GRCm39)	splice site	probably null
R6533:Ptprd	UTSW	4	76,046,765 (GRCm39)	missense	probably damaging	1.00
R6756:Ptprd	UTSW	4	75,873,536 (GRCm39)	missense	probably damaging	1.00
R6782:Ptprd	UTSW	4	76,243,377 (GRCm39)	splice site	probably null
R7131:Ptprd	UTSW	4	75,984,577 (GRCm39)	missense	probably damaging	1.00
R7170:Ptprd	UTSW	4	75,990,199 (GRCm39)	missense	probably benign	0.06
R7233:Ptprd	UTSW	4	75,978,020 (GRCm39)	missense	probably benign	0.00
R7246:Ptprd	UTSW	4	76,046,913 (GRCm39)	missense	probably damaging	1.00
R7413:Ptprd	UTSW	4	76,165,076 (GRCm39)	missense	probably benign	0.00
R7428:Ptprd	UTSW	4	76,004,705 (GRCm39)	missense	probably benign	0.03
R7442:Ptprd	UTSW	4	75,978,058 (GRCm39)	nonsense	probably null
R7491:Ptprd	UTSW	4	76,051,392 (GRCm39)	missense	probably benign	0.23
R7526:Ptprd	UTSW	4	75,984,564 (GRCm39)	missense	probably benign	0.00
R7609:Ptprd	UTSW	4	75,990,240 (GRCm39)	missense	probably benign	0.03
R7612:Ptprd	UTSW	4	76,004,696 (GRCm39)	missense	probably benign	0.45
R7659:Ptprd	UTSW	4	76,047,153 (GRCm39)	missense	probably benign	0.03
R7743:Ptprd	UTSW	4	76,004,326 (GRCm39)	missense	probably damaging	1.00
R7748:Ptprd	UTSW	4	76,017,741 (GRCm39)	missense	probably null	0.39
R7788:Ptprd	UTSW	4	75,916,841 (GRCm39)	missense	probably damaging	1.00
R7836:Ptprd	UTSW	4	75,900,881 (GRCm39)	missense	probably damaging	0.99
R7937:Ptprd	UTSW	4	76,013,772 (GRCm39)	missense	probably benign	0.00
R8000:Ptprd	UTSW	4	75,984,479 (GRCm39)	missense	possibly damaging	0.95
R8018:Ptprd	UTSW	4	76,003,757 (GRCm39)	missense	probably damaging	0.98
R8072:Ptprd	UTSW	4	76,004,273 (GRCm39)	missense	probably benign	0.01
R8119:Ptprd	UTSW	4	76,047,263 (GRCm39)	missense	probably benign	0.00
R8350:Ptprd	UTSW	4	75,868,898 (GRCm39)	missense	probably damaging	1.00
R8387:Ptprd	UTSW	4	75,873,526 (GRCm39)	missense	probably damaging	1.00
R8458:Ptprd	UTSW	4	75,984,496 (GRCm39)	missense	probably benign	0.00
R8529:Ptprd	UTSW	4	76,047,262 (GRCm39)	missense	probably damaging	1.00
R8699:Ptprd	UTSW	4	75,959,629 (GRCm39)	missense	probably benign
R8924:Ptprd	UTSW	4	75,916,736 (GRCm39)	critical splice donor site	probably null
R8984:Ptprd	UTSW	4	75,863,251 (GRCm39)	missense	probably damaging	1.00
R9024:Ptprd	UTSW	4	75,874,567 (GRCm39)	missense	probably damaging	1.00
R9204:Ptprd	UTSW	4	75,872,315 (GRCm39)	missense	possibly damaging	0.46
R9206:Ptprd	UTSW	4	75,872,315 (GRCm39)	missense	possibly damaging	0.46
R9259:Ptprd	UTSW	4	75,990,200 (GRCm39)	missense	probably damaging	0.99
R9311:Ptprd	UTSW	4	76,051,320 (GRCm39)	missense	probably benign	0.25
R9417:Ptprd	UTSW	4	75,865,335 (GRCm39)	missense	probably damaging	0.99
R9427:Ptprd	UTSW	4	76,051,440 (GRCm39)	missense	probably benign	0.01
R9579:Ptprd	UTSW	4	75,872,315 (GRCm39)	missense	possibly damaging	0.46
R9580:Ptprd	UTSW	4	75,872,315 (GRCm39)	missense	possibly damaging	0.46
R9701:Ptprd	UTSW	4	75,916,896 (GRCm39)	missense	probably damaging	1.00
RF016:Ptprd	UTSW	4	76,046,892 (GRCm39)	missense	probably benign	0.01
RF023:Ptprd	UTSW	4	76,046,802 (GRCm39)	missense	probably damaging	0.98
Z1176:Ptprd	UTSW	4	76,051,451 (GRCm39)	missense	probably benign	0.00

Predicted Primers

PCR Primer
(F):5'- AGGAAACTCAGAGACTTGCTTTAC -3'
(R):5'- AGGCCCTTAAACATTTTGATGCAC -3'

Sequencing Primer
(F):5'- ACTCAGAGACTTGCTTTACTAGTTTC -3'
(R):5'- CCCTTAAACATTTTGATGCACTATTG -3'

Posted On

2017-02-16