Incidental Mutation 'R5907:Adamts16'
| ID |
460738 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamts16
|
| Ensembl Gene |
ENSMUSG00000049538 |
| Gene Name |
ADAM metallopeptidase with thrombospondin type 1 motif 16 |
| Synonyms |
|
| MMRRC Submission |
044104-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5907 (G1)
|
| Quality Score |
118 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
70875921-70989930 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 70877029 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Phenylalanine
at position 1204
(C1204F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000079041
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000080145]
[ENSMUST00000123552]
|
| AlphaFold |
Q69Z28 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000080145
AA Change: C1204F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000079041
Gene: ENSMUSG00000049538
AA Change: C1204F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
57 |
203 |
7.8e-34 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
2.9e-13 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
1.2e-8 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
5.4e-32 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
3.7e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
6.4e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
Pfam:ADAM_spacer1
|
744 |
856 |
1.3e-37 |
PFAM |
|
TSP1
|
872 |
926 |
3.48e0 |
SMART |
|
TSP1
|
928 |
985 |
4.84e-3 |
SMART |
|
TSP1
|
987 |
1046 |
1.49e-3 |
SMART |
|
TSP1
|
1052 |
1113 |
3.19e-2 |
SMART |
|
TSP1
|
1127 |
1179 |
7.68e-6 |
SMART |
|
Pfam:PLAC
|
1188 |
1218 |
2.9e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000123552
|
| SMART Domains |
Protein: ENSMUSP00000122031
Gene: ENSMUSG00000049538
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
56 |
203 |
5.9e-33 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
5.1e-14 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
2.2e-9 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
1.2e-33 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
1.2e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
9.7e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000222750
|
| Meta Mutation Damage Score |
0.9495 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.5%
- 10x: 97.9%
- 20x: 93.7%
|
| Validation Efficiency |
93% (92/99) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is co-expressed with the Wilms tumor protein, Wt1, in the developing glomeruli of embryonic kidneys. The encoded preproprotein undergoes proteolytic processing to generate an active enzyme. [provided by RefSeq, Jul 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931429L15Rik |
A |
T |
9: 46,218,120 (GRCm39) |
I206N |
probably damaging |
Het |
| Aadac |
T |
A |
3: 59,947,248 (GRCm39) |
D315E |
probably damaging |
Het |
| Abcc8 |
A |
G |
7: 45,773,330 (GRCm39) |
F800L |
probably benign |
Het |
| Adcy7 |
A |
G |
8: 89,038,856 (GRCm39) |
T291A |
possibly damaging |
Het |
| AI182371 |
G |
T |
2: 34,976,134 (GRCm39) |
Q255K |
possibly damaging |
Het |
| Aig1 |
A |
T |
10: 13,677,528 (GRCm39) |
|
probably benign |
Het |
| Ak5 |
T |
C |
3: 152,321,589 (GRCm39) |
D266G |
probably damaging |
Het |
| Ank1 |
A |
T |
8: 23,630,220 (GRCm39) |
E93D |
probably damaging |
Het |
| Bop1 |
T |
C |
15: 76,340,117 (GRCm39) |
D153G |
probably damaging |
Het |
| Bub1 |
G |
T |
2: 127,661,142 (GRCm39) |
N316K |
probably benign |
Het |
| Capn1 |
T |
C |
19: 6,047,827 (GRCm39) |
N412S |
probably benign |
Het |
| Cdca4 |
A |
G |
12: 112,785,339 (GRCm39) |
S130P |
probably benign |
Het |
| Cdh23 |
A |
T |
10: 60,264,158 (GRCm39) |
D663E |
probably damaging |
Het |
| Clca3a1 |
T |
C |
3: 144,455,403 (GRCm39) |
|
probably benign |
Het |
| Csmd2 |
C |
T |
4: 128,091,178 (GRCm39) |
P239L |
probably damaging |
Het |
| Dlg2 |
A |
T |
7: 91,646,579 (GRCm39) |
|
probably benign |
Het |
| Dnpep |
C |
T |
1: 75,288,635 (GRCm39) |
|
probably null |
Het |
| Dop1b |
A |
T |
16: 93,598,469 (GRCm39) |
H1878L |
probably damaging |
Het |
| Dscam |
C |
T |
16: 96,622,120 (GRCm39) |
D444N |
probably damaging |
Het |
| Emc9 |
C |
T |
14: 55,819,569 (GRCm39) |
|
probably null |
Het |
| Ero1b |
T |
A |
13: 12,615,207 (GRCm39) |
I346N |
probably damaging |
Het |
| Etv3 |
A |
G |
3: 87,442,850 (GRCm39) |
T145A |
probably benign |
Het |
| Fam170a |
T |
A |
18: 50,415,321 (GRCm39) |
|
probably null |
Het |
| Fap |
A |
T |
2: 62,374,700 (GRCm39) |
I261N |
probably damaging |
Het |
| Fbn2 |
T |
C |
18: 58,178,409 (GRCm39) |
N1943S |
probably damaging |
Het |
| Glb1l3 |
A |
T |
9: 26,737,679 (GRCm39) |
V466E |
probably damaging |
Het |
| Gm10521 |
A |
T |
1: 171,724,070 (GRCm39) |
H127L |
unknown |
Het |
| Gm8186 |
G |
T |
17: 26,318,130 (GRCm39) |
N22K |
probably damaging |
Het |
| Gpr132 |
A |
C |
12: 112,815,717 (GRCm39) |
L370V |
probably benign |
Het |
| Hectd1 |
A |
T |
12: 51,845,537 (GRCm39) |
H449Q |
probably damaging |
Het |
| Hook3 |
A |
G |
8: 26,534,306 (GRCm39) |
|
probably benign |
Het |
| Ift140 |
A |
G |
17: 25,311,345 (GRCm39) |
D1180G |
probably benign |
Het |
| Isoc2b |
A |
T |
7: 4,852,577 (GRCm39) |
|
probably null |
Het |
| Itga4 |
C |
T |
2: 79,153,000 (GRCm39) |
H896Y |
probably benign |
Het |
| Itga7 |
T |
C |
10: 128,778,850 (GRCm39) |
Y326H |
probably damaging |
Het |
| Itpr3 |
A |
T |
17: 27,336,867 (GRCm39) |
E2397V |
probably damaging |
Het |
| Jtb |
T |
G |
3: 90,142,884 (GRCm39) |
|
probably null |
Het |
| Klk15 |
A |
G |
7: 43,588,183 (GRCm39) |
T164A |
probably benign |
Het |
| Kmt2e |
C |
A |
5: 23,669,704 (GRCm39) |
H64N |
probably damaging |
Het |
| Lamtor3 |
T |
A |
3: 137,633,054 (GRCm39) |
|
probably benign |
Het |
| Laptm4b |
A |
G |
15: 34,258,830 (GRCm39) |
I35V |
possibly damaging |
Het |
| Lrrc1 |
A |
C |
9: 77,341,379 (GRCm39) |
L393R |
probably damaging |
Het |
| Ltn1 |
A |
G |
16: 87,178,391 (GRCm39) |
S1613P |
possibly damaging |
Het |
| Mtmr4 |
T |
A |
11: 87,502,876 (GRCm39) |
W920R |
probably damaging |
Het |
| Nbeal1 |
T |
C |
1: 60,267,950 (GRCm39) |
|
probably benign |
Het |
| Nup133 |
A |
G |
8: 124,643,038 (GRCm39) |
Y761H |
possibly damaging |
Het |
| Nwd2 |
T |
A |
5: 63,963,326 (GRCm39) |
V970D |
probably damaging |
Het |
| Or4c126 |
A |
G |
2: 89,824,301 (GRCm39) |
H188R |
probably benign |
Het |
| Or6n1 |
T |
C |
1: 173,916,785 (GRCm39) |
Y60H |
probably benign |
Het |
| Or8k24 |
A |
T |
2: 86,216,218 (GRCm39) |
S181R |
probably damaging |
Het |
| Osbp |
C |
T |
19: 11,951,240 (GRCm39) |
L262F |
probably damaging |
Het |
| Phf8-ps |
G |
T |
17: 33,285,124 (GRCm39) |
D559E |
probably benign |
Het |
| Phldb2 |
G |
T |
16: 45,645,551 (GRCm39) |
D343E |
probably damaging |
Het |
| Phrf1 |
T |
A |
7: 140,840,453 (GRCm39) |
M1216K |
possibly damaging |
Het |
| Phyh |
A |
T |
2: 4,935,462 (GRCm39) |
|
probably null |
Het |
| Plekhf1 |
A |
T |
7: 37,921,594 (GRCm39) |
|
probably null |
Het |
| Rars1 |
T |
C |
11: 35,719,475 (GRCm39) |
N116D |
probably damaging |
Het |
| Rnf44 |
T |
A |
13: 54,830,621 (GRCm39) |
Q181L |
possibly damaging |
Het |
| Rpe65 |
T |
C |
3: 159,321,319 (GRCm39) |
|
probably null |
Het |
| Scaf1 |
A |
G |
7: 44,663,016 (GRCm39) |
|
probably benign |
Het |
| Serpinb11 |
A |
T |
1: 107,299,919 (GRCm39) |
R88S |
probably benign |
Het |
| Slc7a7 |
T |
C |
14: 54,616,560 (GRCm39) |
N174S |
probably damaging |
Het |
| Slc9a5 |
T |
C |
8: 106,083,807 (GRCm39) |
|
probably null |
Het |
| Slfn1 |
C |
A |
11: 83,012,002 (GRCm39) |
N39K |
possibly damaging |
Het |
| Snx20 |
G |
A |
8: 89,353,923 (GRCm39) |
A269V |
possibly damaging |
Het |
| Snx6 |
A |
G |
12: 54,801,104 (GRCm39) |
Y298H |
probably damaging |
Het |
| Stk32c |
C |
T |
7: 138,700,590 (GRCm39) |
R213Q |
probably benign |
Het |
| Tgfbr1 |
A |
T |
4: 47,396,555 (GRCm39) |
I190F |
probably damaging |
Het |
| Ube2d2b |
T |
A |
5: 107,978,498 (GRCm39) |
F50I |
probably damaging |
Het |
| Ubl5 |
G |
A |
9: 20,557,830 (GRCm39) |
|
probably benign |
Het |
| Ubqln5 |
T |
G |
7: 103,777,781 (GRCm39) |
T348P |
possibly damaging |
Het |
| Usp46 |
T |
C |
5: 74,197,746 (GRCm39) |
D22G |
probably benign |
Het |
| Vars1 |
A |
G |
17: 35,231,352 (GRCm39) |
N655S |
probably damaging |
Het |
| Vmn2r103 |
A |
C |
17: 20,032,715 (GRCm39) |
I830L |
possibly damaging |
Het |
| Vmn2r26 |
T |
A |
6: 124,016,830 (GRCm39) |
N431K |
probably benign |
Het |
| Vmn2r4 |
G |
T |
3: 64,298,487 (GRCm39) |
P547Q |
probably damaging |
Het |
| Yy1 |
T |
A |
12: 108,772,354 (GRCm39) |
|
probably benign |
Het |
| Zbtb2 |
A |
T |
10: 4,318,592 (GRCm39) |
L478Q |
possibly damaging |
Het |
| Zfp12 |
T |
C |
5: 143,225,743 (GRCm39) |
F17S |
probably damaging |
Het |
| Zfp219 |
T |
A |
14: 52,244,606 (GRCm39) |
|
probably null |
Het |
| Zfp629 |
G |
A |
7: 127,209,542 (GRCm39) |
H756Y |
probably damaging |
Het |
| Zfp748 |
T |
C |
13: 67,689,292 (GRCm39) |
K656R |
possibly damaging |
Het |
| Zfp958 |
T |
A |
8: 4,679,072 (GRCm39) |
Y366N |
probably benign |
Het |
| Zp3 |
C |
T |
5: 136,017,377 (GRCm39) |
T396I |
probably benign |
Het |
|
| Other mutations in Adamts16 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01024:Adamts16
|
APN |
13 |
70,943,603 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01338:Adamts16
|
APN |
13 |
70,984,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01663:Adamts16
|
APN |
13 |
70,941,260 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01804:Adamts16
|
APN |
13 |
70,949,080 (GRCm39) |
nonsense |
probably null |
|
|
IGL01874:Adamts16
|
APN |
13 |
70,916,823 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL01984:Adamts16
|
APN |
13 |
70,935,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02305:Adamts16
|
APN |
13 |
70,921,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02350:Adamts16
|
APN |
13 |
70,886,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02357:Adamts16
|
APN |
13 |
70,886,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02429:Adamts16
|
APN |
13 |
70,935,289 (GRCm39) |
splice site |
probably benign |
|
|
IGL02450:Adamts16
|
APN |
13 |
70,984,419 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02807:Adamts16
|
APN |
13 |
70,886,897 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03356:Adamts16
|
APN |
13 |
70,901,410 (GRCm39) |
missense |
probably benign |
0.00 |
|
swap
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
switcheroo
|
UTSW |
13 |
70,949,073 (GRCm39) |
missense |
probably benign |
|
|
R0046:Adamts16
|
UTSW |
13 |
70,911,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0046:Adamts16
|
UTSW |
13 |
70,911,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0201:Adamts16
|
UTSW |
13 |
70,927,763 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0326:Adamts16
|
UTSW |
13 |
70,927,730 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0336:Adamts16
|
UTSW |
13 |
70,939,913 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R0369:Adamts16
|
UTSW |
13 |
70,927,671 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0422:Adamts16
|
UTSW |
13 |
70,887,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0507:Adamts16
|
UTSW |
13 |
70,916,766 (GRCm39) |
missense |
probably benign |
|
|
R0524:Adamts16
|
UTSW |
13 |
70,949,013 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0590:Adamts16
|
UTSW |
13 |
70,949,073 (GRCm39) |
missense |
probably benign |
|
|
R0734:Adamts16
|
UTSW |
13 |
70,886,600 (GRCm39) |
splice site |
probably benign |
|
|
R0787:Adamts16
|
UTSW |
13 |
70,886,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0826:Adamts16
|
UTSW |
13 |
70,916,811 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0920:Adamts16
|
UTSW |
13 |
70,911,680 (GRCm39) |
splice site |
probably benign |
|
|
R1027:Adamts16
|
UTSW |
13 |
70,915,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1462:Adamts16
|
UTSW |
13 |
70,984,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1462:Adamts16
|
UTSW |
13 |
70,984,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1535:Adamts16
|
UTSW |
13 |
70,939,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1617:Adamts16
|
UTSW |
13 |
70,946,154 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1700:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1734:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1736:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1737:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1738:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1746:Adamts16
|
UTSW |
13 |
70,927,717 (GRCm39) |
splice site |
probably null |
|
|
R1869:Adamts16
|
UTSW |
13 |
70,883,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1944:Adamts16
|
UTSW |
13 |
70,940,005 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1997:Adamts16
|
UTSW |
13 |
70,901,386 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2018:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R2135:Adamts16
|
UTSW |
13 |
70,949,126 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2219:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R2228:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R3410:Adamts16
|
UTSW |
13 |
70,901,345 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3411:Adamts16
|
UTSW |
13 |
70,901,345 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3842:Adamts16
|
UTSW |
13 |
70,887,010 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4117:Adamts16
|
UTSW |
13 |
70,916,111 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4435:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4436:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4526:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4552:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4555:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4556:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4557:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4579:Adamts16
|
UTSW |
13 |
70,927,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4639:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4640:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4641:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4642:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4672:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R5350:Adamts16
|
UTSW |
13 |
70,901,315 (GRCm39) |
nonsense |
probably null |
|
|
R5464:Adamts16
|
UTSW |
13 |
70,909,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5613:Adamts16
|
UTSW |
13 |
70,878,253 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5667:Adamts16
|
UTSW |
13 |
70,984,494 (GRCm39) |
nonsense |
probably null |
|
|
R5735:Adamts16
|
UTSW |
13 |
70,984,337 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5762:Adamts16
|
UTSW |
13 |
70,886,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6169:Adamts16
|
UTSW |
13 |
70,918,393 (GRCm39) |
nonsense |
probably null |
|
|
R6351:Adamts16
|
UTSW |
13 |
70,984,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6665:Adamts16
|
UTSW |
13 |
70,927,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6913:Adamts16
|
UTSW |
13 |
70,877,017 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6982:Adamts16
|
UTSW |
13 |
70,916,639 (GRCm39) |
splice site |
probably null |
|
|
R6996:Adamts16
|
UTSW |
13 |
70,946,157 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7313:Adamts16
|
UTSW |
13 |
70,921,074 (GRCm39) |
nonsense |
probably null |
|
|
R7356:Adamts16
|
UTSW |
13 |
70,984,399 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7509:Adamts16
|
UTSW |
13 |
70,935,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7595:Adamts16
|
UTSW |
13 |
70,878,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Adamts16
|
UTSW |
13 |
70,984,265 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7968:Adamts16
|
UTSW |
13 |
70,886,701 (GRCm39) |
missense |
probably benign |
|
|
R8231:Adamts16
|
UTSW |
13 |
70,925,599 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8232:Adamts16
|
UTSW |
13 |
70,941,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8470:Adamts16
|
UTSW |
13 |
70,984,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Adamts16
|
UTSW |
13 |
70,886,794 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8772:Adamts16
|
UTSW |
13 |
70,984,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Adamts16
|
UTSW |
13 |
70,941,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8921:Adamts16
|
UTSW |
13 |
70,939,910 (GRCm39) |
splice site |
probably benign |
|
|
R8973:Adamts16
|
UTSW |
13 |
70,886,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9132:Adamts16
|
UTSW |
13 |
70,901,408 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9149:Adamts16
|
UTSW |
13 |
70,883,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9159:Adamts16
|
UTSW |
13 |
70,901,408 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9312:Adamts16
|
UTSW |
13 |
70,949,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Adamts16
|
UTSW |
13 |
70,949,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adamts16
|
UTSW |
13 |
70,909,892 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGATCCACTCTAGGTCAAAAGACC -3'
(R):5'- CAAGGCCCCTTTAACAGCTC -3'
Sequencing Primer
(F):5'- TCTAGGTCAAAAGACCCACAGTC -3'
(R):5'- AGCCTCAAGACCCACATTTTCTAGTG -3'
|
| Posted On |
2017-02-28 |
Incidental Mutation