Incidental Mutation 'R5914:Zgrf1'
| ID |
461177 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zgrf1
|
| Ensembl Gene |
ENSMUSG00000051278 |
| Gene Name |
zinc finger, GRF-type containing 1 |
| Synonyms |
4930422G04Rik |
| MMRRC Submission |
044111-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.081)
|
| Stock # |
R5914 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
127347138-127411672 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 127354672 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Histidine
at position 97
(L97H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143585
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043108]
[ENSMUST00000195955]
[ENSMUST00000196141]
[ENSMUST00000199888]
[ENSMUST00000200490]
|
| AlphaFold |
Q0VGT4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000043108
AA Change: L97H
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000044432
Gene: ENSMUSG00000051278
AA Change: L97H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
81 |
3.7e-23 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
906 |
N/A |
INTRINSIC |
|
Pfam:zf-GRF
|
1109 |
1153 |
1.5e-17 |
PFAM |
|
low complexity region
|
1316 |
1328 |
N/A |
INTRINSIC |
|
Pfam:AAA_11
|
1501 |
1608 |
1.6e-21 |
PFAM |
|
Pfam:AAA_12
|
1616 |
1802 |
1.3e-51 |
PFAM |
|
coiled coil region
|
1833 |
1861 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000195955
AA Change: L97H
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000142886
Gene: ENSMUSG00000051278
AA Change: L97H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
82 |
1.6e-25 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000196141
AA Change: L97H
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000143761
Gene: ENSMUSG00000051278
AA Change: L97H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
81 |
3.7e-23 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
906 |
N/A |
INTRINSIC |
|
Pfam:zf-GRF
|
1109 |
1153 |
1.5e-17 |
PFAM |
|
low complexity region
|
1316 |
1328 |
N/A |
INTRINSIC |
|
Pfam:AAA_11
|
1501 |
1608 |
1.6e-21 |
PFAM |
|
Pfam:AAA_12
|
1616 |
1802 |
1.3e-51 |
PFAM |
|
coiled coil region
|
1833 |
1861 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000196949
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000199888
AA Change: L97H
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000142693
Gene: ENSMUSG00000051278
AA Change: L97H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
82 |
3.5e-22 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000200490
AA Change: L97H
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000143585
Gene: ENSMUSG00000051278
AA Change: L97H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF2439
|
3 |
81 |
3.4e-20 |
PFAM |
|
low complexity region
|
92 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
628 |
639 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.4%
- 20x: 95.5%
|
| Validation Efficiency |
95% (87/92) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgrb1 |
G |
A |
15: 74,410,219 (GRCm39) |
R286H |
possibly damaging |
Het |
| Ank3 |
A |
T |
10: 69,828,774 (GRCm39) |
|
probably benign |
Het |
| Arhgap24 |
G |
A |
5: 102,700,025 (GRCm39) |
|
probably null |
Het |
| Arhgef2 |
T |
C |
3: 88,543,176 (GRCm39) |
Y396H |
probably benign |
Het |
| Asap3 |
G |
T |
4: 135,968,720 (GRCm39) |
G722C |
probably benign |
Het |
| Birc2 |
A |
C |
9: 7,857,343 (GRCm39) |
*377E |
probably null |
Het |
| Cdc123 |
G |
T |
2: 5,803,174 (GRCm39) |
Q282K |
possibly damaging |
Het |
| Cdkl4 |
C |
T |
17: 80,855,120 (GRCm39) |
|
probably null |
Het |
| Cep97 |
T |
C |
16: 55,725,820 (GRCm39) |
N689S |
probably benign |
Het |
| Cfap97 |
T |
G |
8: 46,634,895 (GRCm39) |
S407A |
probably damaging |
Het |
| Cfh |
A |
T |
1: 140,063,967 (GRCm39) |
N436K |
probably benign |
Het |
| Chpf2 |
A |
T |
5: 24,797,421 (GRCm39) |
|
probably benign |
Het |
| Cnnm2 |
A |
G |
19: 46,751,616 (GRCm39) |
T469A |
probably benign |
Het |
| Col6a3 |
T |
A |
1: 90,703,922 (GRCm39) |
I2275F |
unknown |
Het |
| Ctdspl2 |
A |
T |
2: 121,809,414 (GRCm39) |
N122Y |
probably damaging |
Het |
| Dcaf6 |
A |
T |
1: 165,178,724 (GRCm39) |
C602S |
probably benign |
Het |
| Dda1 |
T |
A |
8: 71,927,294 (GRCm39) |
|
probably benign |
Het |
| Dixdc1 |
T |
C |
9: 50,609,888 (GRCm39) |
|
probably benign |
Het |
| Dnah2 |
C |
T |
11: 69,349,746 (GRCm39) |
R2399Q |
probably benign |
Het |
| Emilin3 |
T |
A |
2: 160,750,990 (GRCm39) |
N253I |
probably damaging |
Het |
| Epg5 |
T |
A |
18: 78,002,847 (GRCm39) |
|
probably null |
Het |
| Fam204a |
A |
T |
19: 60,209,525 (GRCm39) |
Y68* |
probably null |
Het |
| Fbln5 |
T |
G |
12: 101,727,002 (GRCm39) |
D329A |
possibly damaging |
Het |
| Fkbp15 |
T |
A |
4: 62,246,047 (GRCm39) |
|
probably null |
Het |
| Fnbp4 |
C |
G |
2: 90,605,137 (GRCm39) |
|
probably benign |
Het |
| Foxn2 |
C |
A |
17: 88,770,138 (GRCm39) |
|
probably null |
Het |
| Frem1 |
T |
C |
4: 82,920,012 (GRCm39) |
D448G |
probably damaging |
Het |
| Fzd9 |
T |
C |
5: 135,278,199 (GRCm39) |
Y562C |
probably benign |
Het |
| Gcn1 |
A |
G |
5: 115,748,194 (GRCm39) |
|
silent |
Het |
| Gm6003 |
A |
G |
7: 32,864,691 (GRCm39) |
|
noncoding transcript |
Het |
| Gnl3 |
C |
A |
14: 30,738,853 (GRCm39) |
E65D |
possibly damaging |
Het |
| Hax1 |
GTCATCATCATCATCATC |
GTCATCATCATCATCATCATC |
3: 89,905,247 (GRCm39) |
|
probably benign |
Het |
| Hk2 |
C |
T |
6: 82,713,615 (GRCm39) |
R461K |
probably benign |
Het |
| Ice1 |
A |
G |
13: 70,754,496 (GRCm39) |
F530S |
possibly damaging |
Het |
| Ing3 |
T |
A |
6: 21,968,904 (GRCm39) |
S129T |
probably benign |
Het |
| Ino80 |
G |
A |
2: 119,288,697 (GRCm39) |
S3L |
probably damaging |
Het |
| Ints2 |
T |
A |
11: 86,113,000 (GRCm39) |
Q839H |
probably benign |
Het |
| Kcnrg |
T |
C |
14: 61,849,280 (GRCm39) |
M247T |
probably benign |
Het |
| Kpna6 |
T |
C |
4: 129,566,485 (GRCm39) |
|
probably benign |
Het |
| Krtap28-13 |
T |
A |
1: 83,039,044 (GRCm39) |
|
probably benign |
Het |
| Lgr4 |
T |
A |
2: 109,748,617 (GRCm39) |
V51E |
possibly damaging |
Het |
| Map3k5 |
A |
C |
10: 19,980,001 (GRCm39) |
E836D |
probably benign |
Het |
| Mapk11 |
T |
C |
15: 89,030,038 (GRCm39) |
I193V |
probably benign |
Het |
| Marchf10 |
A |
T |
11: 105,276,308 (GRCm39) |
V660E |
probably damaging |
Het |
| Matn4 |
T |
C |
2: 164,235,144 (GRCm39) |
E435G |
probably damaging |
Het |
| Mre11a |
G |
T |
9: 14,723,232 (GRCm39) |
R402M |
probably damaging |
Het |
| Msr1 |
C |
T |
8: 40,034,868 (GRCm39) |
G428R |
probably damaging |
Het |
| Ndufv3 |
C |
T |
17: 31,750,206 (GRCm39) |
R99* |
probably null |
Het |
| Nkx6-1 |
C |
T |
5: 101,811,847 (GRCm39) |
S85N |
unknown |
Het |
| Nop2 |
A |
T |
6: 125,111,691 (GRCm39) |
E141D |
probably benign |
Het |
| Or5b3 |
A |
G |
19: 13,388,326 (GRCm39) |
H131R |
probably benign |
Het |
| Or8b1 |
G |
C |
9: 38,399,657 (GRCm39) |
E111Q |
probably damaging |
Het |
| Paox |
T |
C |
7: 139,709,101 (GRCm39) |
S205P |
probably damaging |
Het |
| Pcdh15 |
T |
C |
10: 74,466,768 (GRCm39) |
V995A |
probably benign |
Het |
| Pdcd1 |
T |
A |
1: 93,968,550 (GRCm39) |
K161N |
probably benign |
Het |
| Pfkfb2 |
C |
A |
1: 130,627,832 (GRCm39) |
V372L |
probably damaging |
Het |
| Phldb1 |
G |
A |
9: 44,622,948 (GRCm39) |
T19I |
probably damaging |
Het |
| Pik3c2g |
G |
T |
6: 139,599,477 (GRCm39) |
V198L |
probably benign |
Het |
| Pnpla8 |
T |
A |
12: 44,342,753 (GRCm39) |
L41* |
probably null |
Het |
| Postn |
C |
T |
3: 54,281,221 (GRCm39) |
Q449* |
probably null |
Het |
| Ppp1r3a |
C |
T |
6: 14,718,988 (GRCm39) |
S642N |
probably benign |
Het |
| Ptpn23 |
G |
A |
9: 110,214,511 (GRCm39) |
|
probably benign |
Het |
| Ptprj |
T |
C |
2: 90,283,684 (GRCm39) |
N923S |
possibly damaging |
Het |
| Rai1 |
T |
C |
11: 60,078,630 (GRCm39) |
V898A |
probably benign |
Het |
| Rasgef1a |
A |
T |
6: 118,057,515 (GRCm39) |
Y72F |
possibly damaging |
Het |
| Serpinb7 |
T |
C |
1: 107,379,580 (GRCm39) |
V329A |
probably damaging |
Het |
| Slc24a4 |
T |
A |
12: 102,201,049 (GRCm39) |
I311N |
probably damaging |
Het |
| Slc45a1 |
C |
A |
4: 150,713,997 (GRCm39) |
L749F |
possibly damaging |
Het |
| Spon1 |
G |
A |
7: 113,630,056 (GRCm39) |
D428N |
probably damaging |
Het |
| Tcf7l2 |
G |
A |
19: 55,886,992 (GRCm39) |
E2K |
probably benign |
Het |
| Thoc5 |
A |
G |
11: 4,870,416 (GRCm39) |
M472V |
possibly damaging |
Het |
| Tm6sf2 |
T |
C |
8: 70,528,213 (GRCm39) |
Y121H |
probably damaging |
Het |
| Tmc4 |
T |
A |
7: 3,675,008 (GRCm39) |
D221V |
probably benign |
Het |
| Trim30b |
A |
T |
7: 104,006,572 (GRCm39) |
S95T |
probably damaging |
Het |
| Trip12 |
T |
C |
1: 84,741,179 (GRCm39) |
E571G |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,781,656 (GRCm39) |
|
probably null |
Het |
| Ubp1 |
A |
T |
9: 113,785,807 (GRCm39) |
R161W |
probably benign |
Het |
| Usp21 |
G |
A |
1: 171,109,745 (GRCm39) |
|
probably benign |
Het |
| Vmn1r61 |
T |
A |
7: 5,613,529 (GRCm39) |
R262W |
probably damaging |
Het |
| Vmn2r67 |
A |
T |
7: 84,801,044 (GRCm39) |
D297E |
probably damaging |
Het |
| Vwa5a |
T |
C |
9: 38,653,038 (GRCm39) |
L784S |
probably benign |
Het |
| Vwc2 |
G |
A |
11: 11,104,244 (GRCm39) |
V259M |
probably damaging |
Het |
| Zeb2 |
T |
C |
2: 44,887,064 (GRCm39) |
I596M |
probably benign |
Het |
|
| Other mutations in Zgrf1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01088:Zgrf1
|
APN |
3 |
127,381,790 (GRCm39) |
splice site |
probably benign |
|
|
IGL01153:Zgrf1
|
APN |
3 |
127,396,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01330:Zgrf1
|
APN |
3 |
127,377,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01501:Zgrf1
|
APN |
3 |
127,396,211 (GRCm39) |
splice site |
probably null |
|
|
IGL01827:Zgrf1
|
APN |
3 |
127,409,930 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02600:Zgrf1
|
APN |
3 |
127,394,623 (GRCm39) |
splice site |
probably benign |
|
|
IGL03122:Zgrf1
|
APN |
3 |
127,381,782 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03365:Zgrf1
|
APN |
3 |
127,392,423 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R0015_Zgrf1_014
|
UTSW |
3 |
127,349,046 (GRCm39) |
splice site |
probably benign |
|
|
R1298_Zgrf1_204
|
UTSW |
3 |
127,377,538 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7175_zgrf1_533
|
UTSW |
3 |
127,357,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0015:Zgrf1
|
UTSW |
3 |
127,349,046 (GRCm39) |
splice site |
probably benign |
|
|
R0243:Zgrf1
|
UTSW |
3 |
127,409,095 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0468:Zgrf1
|
UTSW |
3 |
127,355,690 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R0497:Zgrf1
|
UTSW |
3 |
127,378,299 (GRCm39) |
splice site |
probably benign |
|
|
R0505:Zgrf1
|
UTSW |
3 |
127,366,887 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0511:Zgrf1
|
UTSW |
3 |
127,378,309 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0539:Zgrf1
|
UTSW |
3 |
127,408,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0617:Zgrf1
|
UTSW |
3 |
127,381,687 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1298:Zgrf1
|
UTSW |
3 |
127,377,538 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1353:Zgrf1
|
UTSW |
3 |
127,405,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1593:Zgrf1
|
UTSW |
3 |
127,354,675 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1846:Zgrf1
|
UTSW |
3 |
127,409,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1912:Zgrf1
|
UTSW |
3 |
127,356,786 (GRCm39) |
missense |
probably benign |
|
|
R2062:Zgrf1
|
UTSW |
3 |
127,406,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2064:Zgrf1
|
UTSW |
3 |
127,406,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2065:Zgrf1
|
UTSW |
3 |
127,406,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2066:Zgrf1
|
UTSW |
3 |
127,406,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2067:Zgrf1
|
UTSW |
3 |
127,406,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2256:Zgrf1
|
UTSW |
3 |
127,355,646 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2321:Zgrf1
|
UTSW |
3 |
127,356,056 (GRCm39) |
nonsense |
probably null |
|
|
R2381:Zgrf1
|
UTSW |
3 |
127,349,863 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2913:Zgrf1
|
UTSW |
3 |
127,392,356 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R3147:Zgrf1
|
UTSW |
3 |
127,377,797 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R3236:Zgrf1
|
UTSW |
3 |
127,407,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3237:Zgrf1
|
UTSW |
3 |
127,407,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4433:Zgrf1
|
UTSW |
3 |
127,355,727 (GRCm39) |
missense |
probably benign |
|
|
R4441:Zgrf1
|
UTSW |
3 |
127,379,786 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R4457:Zgrf1
|
UTSW |
3 |
127,389,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4498:Zgrf1
|
UTSW |
3 |
127,379,749 (GRCm39) |
nonsense |
probably null |
|
|
R4598:Zgrf1
|
UTSW |
3 |
127,394,679 (GRCm39) |
missense |
probably benign |
0.14 |
|
R4701:Zgrf1
|
UTSW |
3 |
127,392,353 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4898:Zgrf1
|
UTSW |
3 |
127,396,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4944:Zgrf1
|
UTSW |
3 |
127,355,517 (GRCm39) |
nonsense |
probably null |
|
|
R5256:Zgrf1
|
UTSW |
3 |
127,396,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5294:Zgrf1
|
UTSW |
3 |
127,394,629 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5358:Zgrf1
|
UTSW |
3 |
127,361,352 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5359:Zgrf1
|
UTSW |
3 |
127,394,814 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5447:Zgrf1
|
UTSW |
3 |
127,356,768 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5569:Zgrf1
|
UTSW |
3 |
127,354,674 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5887:Zgrf1
|
UTSW |
3 |
127,378,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5925:Zgrf1
|
UTSW |
3 |
127,366,853 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5936:Zgrf1
|
UTSW |
3 |
127,355,902 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6087:Zgrf1
|
UTSW |
3 |
127,409,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6089:Zgrf1
|
UTSW |
3 |
127,389,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6181:Zgrf1
|
UTSW |
3 |
127,381,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6277:Zgrf1
|
UTSW |
3 |
127,392,461 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6441:Zgrf1
|
UTSW |
3 |
127,381,683 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6659:Zgrf1
|
UTSW |
3 |
127,410,155 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6857:Zgrf1
|
UTSW |
3 |
127,375,096 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6932:Zgrf1
|
UTSW |
3 |
127,353,281 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7008:Zgrf1
|
UTSW |
3 |
127,355,421 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7175:Zgrf1
|
UTSW |
3 |
127,357,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7264:Zgrf1
|
UTSW |
3 |
127,357,218 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7272:Zgrf1
|
UTSW |
3 |
127,392,409 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7298:Zgrf1
|
UTSW |
3 |
127,377,299 (GRCm39) |
nonsense |
probably null |
|
|
R7412:Zgrf1
|
UTSW |
3 |
127,356,720 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7836:Zgrf1
|
UTSW |
3 |
127,357,080 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7945:Zgrf1
|
UTSW |
3 |
127,356,409 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7996:Zgrf1
|
UTSW |
3 |
127,389,573 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8165:Zgrf1
|
UTSW |
3 |
127,357,032 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R8198:Zgrf1
|
UTSW |
3 |
127,389,673 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8296:Zgrf1
|
UTSW |
3 |
127,377,644 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8298:Zgrf1
|
UTSW |
3 |
127,408,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8341:Zgrf1
|
UTSW |
3 |
127,354,564 (GRCm39) |
nonsense |
probably null |
|
|
R8445:Zgrf1
|
UTSW |
3 |
127,379,854 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9088:Zgrf1
|
UTSW |
3 |
127,377,326 (GRCm39) |
missense |
probably benign |
0.21 |
|
R9236:Zgrf1
|
UTSW |
3 |
127,378,312 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9250:Zgrf1
|
UTSW |
3 |
127,379,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9253:Zgrf1
|
UTSW |
3 |
127,392,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9464:Zgrf1
|
UTSW |
3 |
127,377,741 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9647:Zgrf1
|
UTSW |
3 |
127,355,251 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9680:Zgrf1
|
UTSW |
3 |
127,409,216 (GRCm39) |
missense |
probably benign |
0.38 |
|
RF015:Zgrf1
|
UTSW |
3 |
127,356,882 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTGCTTGAATAGTTGAATGTTCACTGC -3'
(R):5'- GTTCCTAAGTAAACAATGAAGCACC -3'
Sequencing Primer
(F):5'- AGTTGAATGTTCACTGCATCTTG -3'
(R):5'- TGAAGCACCATTTTAACAGCAAC -3'
|
| Posted On |
2017-02-28 |
Incidental Mutation