Incidental Mutation 'R5933:Gapvd1'
| ID |
461978 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Gapvd1
|
| Ensembl Gene |
ENSMUSG00000026867 |
| Gene Name |
GTPase activating protein and VPS9 domains 1 |
| Synonyms |
2010005B09Rik, 4432404J10Rik |
| MMRRC Submission |
044127-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R5933 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
34566190-34645297 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 34574303 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 1265
(S1265G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000099864
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028224]
[ENSMUST00000102800]
[ENSMUST00000113099]
|
| AlphaFold |
Q6PAR5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000028224
AA Change: S1265G
PolyPhen 2
Score 0.268 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000028224
Gene: ENSMUSG00000026867
AA Change: S1265G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RasGAP
|
152 |
353 |
2.3e-36 |
PFAM |
|
internal_repeat_1
|
626 |
655 |
3.27e-5 |
PROSPERO |
|
low complexity region
|
664 |
678 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
686 |
717 |
3.27e-5 |
PROSPERO |
|
low complexity region
|
875 |
890 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
923 |
933 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
952 |
N/A |
INTRINSIC |
|
low complexity region
|
972 |
982 |
N/A |
INTRINSIC |
|
VPS9
|
1332 |
1437 |
1.08e-24 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102800
AA Change: S1265G
PolyPhen 2
Score 0.268 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000099864
Gene: ENSMUSG00000026867
AA Change: S1265G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RasGAP
|
152 |
353 |
2.3e-36 |
PFAM |
|
internal_repeat_1
|
626 |
655 |
3.27e-5 |
PROSPERO |
|
low complexity region
|
664 |
678 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
686 |
717 |
3.27e-5 |
PROSPERO |
|
low complexity region
|
875 |
890 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
923 |
933 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
952 |
N/A |
INTRINSIC |
|
low complexity region
|
972 |
982 |
N/A |
INTRINSIC |
|
VPS9
|
1332 |
1437 |
1.08e-24 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113099
AA Change: S1286G
PolyPhen 2
Score 0.188 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000108723
Gene: ENSMUSG00000026867
AA Change: S1286G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RasGAP
|
152 |
353 |
2.8e-37 |
PFAM |
|
internal_repeat_1
|
647 |
676 |
3.6e-5 |
PROSPERO |
|
low complexity region
|
685 |
699 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
707 |
738 |
3.6e-5 |
PROSPERO |
|
low complexity region
|
896 |
911 |
N/A |
INTRINSIC |
|
low complexity region
|
930 |
941 |
N/A |
INTRINSIC |
|
low complexity region
|
944 |
954 |
N/A |
INTRINSIC |
|
low complexity region
|
957 |
973 |
N/A |
INTRINSIC |
|
low complexity region
|
993 |
1003 |
N/A |
INTRINSIC |
|
VPS9
|
1353 |
1458 |
1.08e-24 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000113101
AA Change: S375G
|
| SMART Domains |
Protein: ENSMUSP00000108725
Gene: ENSMUSG00000026867
AA Change: S375G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
47 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
71 |
N/A |
INTRINSIC |
|
low complexity region
|
74 |
90 |
N/A |
INTRINSIC |
|
VPS9
|
443 |
548 |
1.08e-24 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000113111
AA Change: S723G
|
| SMART Domains |
Protein: ENSMUSP00000108735
Gene: ENSMUSG00000026867
AA Change: S723G
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
85 |
114 |
3.65e-6 |
PROSPERO |
|
low complexity region
|
123 |
137 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
145 |
176 |
3.65e-6 |
PROSPERO |
|
low complexity region
|
334 |
349 |
N/A |
INTRINSIC |
|
low complexity region
|
368 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
382 |
392 |
N/A |
INTRINSIC |
|
low complexity region
|
395 |
411 |
N/A |
INTRINSIC |
|
low complexity region
|
431 |
441 |
N/A |
INTRINSIC |
|
VPS9
|
791 |
896 |
1.08e-24 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000138203
AA Change: S1G
|
| Meta Mutation Damage Score |
0.2743 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.2%
- 20x: 95.1%
|
| Validation Efficiency |
94% (99/105) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
C |
T |
3: 137,776,109 (GRCm39) |
P1766L |
probably damaging |
Het |
| Abca13 |
A |
G |
11: 9,199,658 (GRCm39) |
Q119R |
possibly damaging |
Het |
| Acot11 |
C |
T |
4: 106,617,327 (GRCm39) |
G240R |
probably damaging |
Het |
| Aipl1 |
A |
C |
11: 71,921,108 (GRCm39) |
C237G |
probably benign |
Het |
| Ankdd1a |
C |
T |
9: 65,416,978 (GRCm39) |
A154T |
probably benign |
Het |
| Arglu1 |
T |
C |
8: 8,740,047 (GRCm39) |
S91G |
probably benign |
Het |
| Arhgef33 |
C |
A |
17: 80,644,709 (GRCm39) |
H13N |
probably benign |
Het |
| Atp1a4 |
A |
G |
1: 172,059,841 (GRCm39) |
I796T |
possibly damaging |
Het |
| Birc6 |
C |
G |
17: 74,906,232 (GRCm39) |
S1374R |
probably damaging |
Het |
| Birc6 |
T |
A |
17: 74,906,233 (GRCm39) |
S72T |
probably damaging |
Het |
| Bmpr1b |
T |
C |
3: 141,577,128 (GRCm39) |
*59W |
probably null |
Het |
| Btbd16 |
A |
T |
7: 130,386,011 (GRCm39) |
Q63L |
probably damaging |
Het |
| Cacna1c |
C |
T |
6: 118,589,541 (GRCm39) |
R1592H |
probably damaging |
Het |
| Caps2 |
G |
A |
10: 112,051,351 (GRCm39) |
E541K |
probably benign |
Het |
| Card9 |
T |
C |
2: 26,242,509 (GRCm39) |
E500G |
probably damaging |
Het |
| Carnmt1 |
T |
C |
19: 18,681,469 (GRCm39) |
V396A |
probably benign |
Het |
| Ccnl1 |
T |
A |
3: 65,855,763 (GRCm39) |
K320M |
probably damaging |
Het |
| Cdh20 |
A |
C |
1: 104,912,396 (GRCm39) |
D550A |
probably damaging |
Het |
| Cdhr1 |
T |
A |
14: 36,811,419 (GRCm39) |
T231S |
probably benign |
Het |
| Cenpe |
T |
C |
3: 134,967,389 (GRCm39) |
V2177A |
probably benign |
Het |
| Cfap69 |
A |
G |
5: 5,690,183 (GRCm39) |
C161R |
probably damaging |
Het |
| Ctsd |
C |
T |
7: 141,930,316 (GRCm39) |
V403I |
probably benign |
Het |
| Cyth1 |
C |
T |
11: 118,076,585 (GRCm39) |
|
probably null |
Het |
| Dazl |
A |
T |
17: 50,594,781 (GRCm39) |
|
probably null |
Het |
| Disp3 |
A |
T |
4: 148,325,770 (GRCm39) |
C1329* |
probably null |
Het |
| Dld |
C |
T |
12: 31,383,982 (GRCm39) |
V374I |
probably benign |
Het |
| Dnah7c |
T |
C |
1: 46,558,375 (GRCm39) |
Y494H |
probably damaging |
Het |
| Dnttip2 |
T |
A |
3: 122,069,217 (GRCm39) |
M144K |
probably benign |
Het |
| Drc1 |
A |
T |
5: 30,502,873 (GRCm39) |
D132V |
probably damaging |
Het |
| Enpp6 |
A |
G |
8: 47,519,039 (GRCm39) |
D269G |
probably benign |
Het |
| Ephx4 |
T |
A |
5: 107,551,631 (GRCm39) |
|
probably null |
Het |
| Evl |
T |
C |
12: 108,649,516 (GRCm39) |
S345P |
possibly damaging |
Het |
| Fam193a |
A |
T |
5: 34,623,024 (GRCm39) |
D1204V |
probably damaging |
Het |
| Fat2 |
A |
T |
11: 55,174,877 (GRCm39) |
D1945E |
probably damaging |
Het |
| Fat4 |
T |
C |
3: 39,005,524 (GRCm39) |
|
probably null |
Het |
| Fbln7 |
A |
T |
2: 128,719,418 (GRCm39) |
M72L |
probably benign |
Het |
| Flnc |
T |
C |
6: 29,441,105 (GRCm39) |
V353A |
probably damaging |
Het |
| Fry |
T |
C |
5: 150,314,265 (GRCm39) |
|
probably benign |
Het |
| Galnt14 |
A |
T |
17: 73,833,300 (GRCm39) |
C225S |
probably benign |
Het |
| Gm13030 |
A |
G |
4: 138,598,515 (GRCm39) |
F136S |
unknown |
Het |
| Gucy1a1 |
T |
C |
3: 82,002,114 (GRCm39) |
H655R |
probably damaging |
Het |
| Hk1 |
A |
G |
10: 62,105,773 (GRCm39) |
L890P |
probably damaging |
Het |
| Igfn1 |
T |
A |
1: 135,898,341 (GRCm39) |
R742* |
probably null |
Het |
| Igkv12-49 |
T |
C |
6: 69,693,553 (GRCm39) |
|
noncoding transcript |
Het |
| Igkv2-109 |
T |
A |
6: 68,279,965 (GRCm39) |
L62Q |
possibly damaging |
Het |
| Itgb3 |
A |
G |
11: 104,528,805 (GRCm39) |
T311A |
possibly damaging |
Het |
| Kl |
A |
G |
5: 150,912,948 (GRCm39) |
E899G |
probably damaging |
Het |
| Kyat3 |
A |
T |
3: 142,429,021 (GRCm39) |
D151V |
probably damaging |
Het |
| Morc2b |
A |
T |
17: 33,357,583 (GRCm39) |
M63K |
possibly damaging |
Het |
| Mtbp |
T |
A |
15: 55,434,723 (GRCm39) |
F298L |
possibly damaging |
Het |
| Mtmr3 |
C |
T |
11: 4,448,951 (GRCm39) |
V272I |
probably benign |
Het |
| Muc4 |
A |
G |
16: 32,574,480 (GRCm39) |
T977A |
probably benign |
Het |
| Nebl |
G |
A |
2: 17,408,998 (GRCm39) |
H367Y |
probably benign |
Het |
| Nop58 |
T |
A |
1: 59,743,824 (GRCm39) |
Y274* |
probably null |
Het |
| Nuak1 |
T |
A |
10: 84,210,666 (GRCm39) |
Q474L |
probably damaging |
Het |
| Obscn |
A |
G |
11: 58,889,331 (GRCm39) |
S7523P |
unknown |
Het |
| Oosp3 |
T |
A |
19: 11,682,753 (GRCm39) |
D140E |
probably benign |
Het |
| Or52z15 |
T |
A |
7: 103,332,680 (GRCm39) |
C242S |
probably damaging |
Het |
| Padi2 |
G |
A |
4: 140,644,952 (GRCm39) |
R62H |
probably benign |
Het |
| Patl1 |
A |
G |
19: 11,917,136 (GRCm39) |
N661S |
probably benign |
Het |
| Pcyox1l |
G |
T |
18: 61,831,544 (GRCm39) |
N238K |
probably benign |
Het |
| Pmch |
A |
G |
10: 87,927,011 (GRCm39) |
T5A |
probably benign |
Het |
| Polr3h |
A |
G |
15: 81,800,835 (GRCm39) |
L169P |
probably damaging |
Het |
| Ptpn4 |
A |
G |
1: 119,615,453 (GRCm39) |
V567A |
probably damaging |
Het |
| Rasgrp2 |
T |
G |
19: 6,452,543 (GRCm39) |
F39V |
probably damaging |
Het |
| Setd1b |
G |
A |
5: 123,296,815 (GRCm39) |
|
probably benign |
Het |
| Sh3glb2 |
A |
T |
2: 30,240,401 (GRCm39) |
|
probably null |
Het |
| Slc46a3 |
A |
T |
5: 147,830,700 (GRCm39) |
N44K |
probably benign |
Het |
| Slc9b1 |
T |
A |
3: 135,099,756 (GRCm39) |
N425K |
probably benign |
Het |
| Slfn14 |
A |
T |
11: 83,170,288 (GRCm39) |
V452E |
probably damaging |
Het |
| Slfn8 |
A |
T |
11: 82,894,161 (GRCm39) |
M826K |
probably benign |
Het |
| Slit3 |
G |
A |
11: 35,520,578 (GRCm39) |
V572M |
probably benign |
Het |
| Smr3a |
C |
A |
5: 88,155,873 (GRCm39) |
|
probably null |
Het |
| Snap29 |
T |
C |
16: 17,224,194 (GRCm39) |
S70P |
probably damaging |
Het |
| Svopl |
T |
A |
6: 37,993,949 (GRCm39) |
|
probably benign |
Het |
| Tbc1d17 |
A |
T |
7: 44,494,761 (GRCm39) |
F186I |
probably damaging |
Het |
| Tgm6 |
T |
C |
2: 129,983,176 (GRCm39) |
V255A |
probably damaging |
Het |
| Tjp1 |
G |
T |
7: 64,952,600 (GRCm39) |
T1498K |
probably benign |
Het |
| Tkfc |
C |
A |
19: 10,574,711 (GRCm39) |
E176D |
probably benign |
Het |
| Tmem102 |
C |
T |
11: 69,694,506 (GRCm39) |
V489I |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,551,781 (GRCm39) |
V22930A |
probably damaging |
Het |
| Tyms |
A |
T |
5: 30,278,357 (GRCm39) |
|
probably null |
Het |
| Uaca |
T |
A |
9: 60,748,238 (GRCm39) |
D67E |
probably damaging |
Het |
| Unc119b |
G |
A |
5: 115,265,508 (GRCm39) |
|
probably benign |
Het |
| Usp29 |
A |
T |
7: 6,964,744 (GRCm39) |
T196S |
probably benign |
Het |
| Usp37 |
A |
G |
1: 74,525,141 (GRCm39) |
S228P |
probably damaging |
Het |
| Usp42 |
C |
A |
5: 143,701,270 (GRCm39) |
A918S |
probably benign |
Het |
| Vmn2r72 |
T |
A |
7: 85,387,058 (GRCm39) |
L835F |
probably benign |
Het |
| Vps13a |
T |
C |
19: 16,637,894 (GRCm39) |
T2396A |
probably benign |
Het |
| Whrn |
A |
T |
4: 63,412,945 (GRCm39) |
S176T |
probably damaging |
Het |
| Zbtb42 |
T |
C |
12: 112,647,055 (GRCm39) |
F410S |
probably damaging |
Het |
| Zfp616 |
T |
C |
11: 73,973,952 (GRCm39) |
S74P |
probably damaging |
Het |
| Zswim6 |
A |
G |
13: 107,880,642 (GRCm39) |
|
noncoding transcript |
Het |
|
| Other mutations in Gapvd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00799:Gapvd1
|
APN |
2 |
34,589,872 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00985:Gapvd1
|
APN |
2 |
34,585,575 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01133:Gapvd1
|
APN |
2 |
34,615,410 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01347:Gapvd1
|
APN |
2 |
34,596,708 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01830:Gapvd1
|
APN |
2 |
34,578,968 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01865:Gapvd1
|
APN |
2 |
34,585,515 (GRCm39) |
missense |
probably null |
|
|
IGL02009:Gapvd1
|
APN |
2 |
34,594,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02014:Gapvd1
|
APN |
2 |
34,594,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02189:Gapvd1
|
APN |
2 |
34,618,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02418:Gapvd1
|
APN |
2 |
34,620,530 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02632:Gapvd1
|
APN |
2 |
34,574,186 (GRCm39) |
splice site |
probably benign |
|
|
IGL02636:Gapvd1
|
APN |
2 |
34,615,416 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02643:Gapvd1
|
APN |
2 |
34,594,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03271:Gapvd1
|
APN |
2 |
34,617,219 (GRCm39) |
unclassified |
probably benign |
|
|
P0023:Gapvd1
|
UTSW |
2 |
34,596,700 (GRCm39) |
splice site |
probably benign |
|
|
R0016:Gapvd1
|
UTSW |
2 |
34,589,925 (GRCm39) |
splice site |
probably benign |
|
|
R0016:Gapvd1
|
UTSW |
2 |
34,589,925 (GRCm39) |
splice site |
probably benign |
|
|
R0029:Gapvd1
|
UTSW |
2 |
34,568,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0029:Gapvd1
|
UTSW |
2 |
34,568,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0282:Gapvd1
|
UTSW |
2 |
34,578,972 (GRCm39) |
nonsense |
probably null |
|
|
R0414:Gapvd1
|
UTSW |
2 |
34,583,439 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0443:Gapvd1
|
UTSW |
2 |
34,594,633 (GRCm39) |
intron |
probably benign |
|
|
R0542:Gapvd1
|
UTSW |
2 |
34,615,048 (GRCm39) |
unclassified |
probably benign |
|
|
R0570:Gapvd1
|
UTSW |
2 |
34,618,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0840:Gapvd1
|
UTSW |
2 |
34,619,125 (GRCm39) |
missense |
probably benign |
0.29 |
|
R0866:Gapvd1
|
UTSW |
2 |
34,599,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0890:Gapvd1
|
UTSW |
2 |
34,602,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0926:Gapvd1
|
UTSW |
2 |
34,602,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0970:Gapvd1
|
UTSW |
2 |
34,620,625 (GRCm39) |
splice site |
probably null |
|
|
R1168:Gapvd1
|
UTSW |
2 |
34,594,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1391:Gapvd1
|
UTSW |
2 |
34,596,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1577:Gapvd1
|
UTSW |
2 |
34,599,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Gapvd1
|
UTSW |
2 |
34,602,207 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1669:Gapvd1
|
UTSW |
2 |
34,620,694 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1677:Gapvd1
|
UTSW |
2 |
34,590,773 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1812:Gapvd1
|
UTSW |
2 |
34,615,076 (GRCm39) |
nonsense |
probably null |
|
|
R1874:Gapvd1
|
UTSW |
2 |
34,596,033 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1878:Gapvd1
|
UTSW |
2 |
34,615,212 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1974:Gapvd1
|
UTSW |
2 |
34,590,853 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2111:Gapvd1
|
UTSW |
2 |
34,574,329 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2921:Gapvd1
|
UTSW |
2 |
34,578,875 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2923:Gapvd1
|
UTSW |
2 |
34,578,875 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3846:Gapvd1
|
UTSW |
2 |
34,619,084 (GRCm39) |
nonsense |
probably null |
|
|
R3894:Gapvd1
|
UTSW |
2 |
34,618,488 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4405:Gapvd1
|
UTSW |
2 |
34,618,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4605:Gapvd1
|
UTSW |
2 |
34,618,549 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4770:Gapvd1
|
UTSW |
2 |
34,581,193 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4935:Gapvd1
|
UTSW |
2 |
34,594,504 (GRCm39) |
nonsense |
probably null |
|
|
R5218:Gapvd1
|
UTSW |
2 |
34,618,488 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5490:Gapvd1
|
UTSW |
2 |
34,583,445 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5571:Gapvd1
|
UTSW |
2 |
34,605,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5588:Gapvd1
|
UTSW |
2 |
34,599,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6117:Gapvd1
|
UTSW |
2 |
34,580,471 (GRCm39) |
splice site |
probably null |
|
|
R6661:Gapvd1
|
UTSW |
2 |
34,618,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6857:Gapvd1
|
UTSW |
2 |
34,618,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6950:Gapvd1
|
UTSW |
2 |
34,574,257 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7009:Gapvd1
|
UTSW |
2 |
34,590,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7125:Gapvd1
|
UTSW |
2 |
34,585,612 (GRCm39) |
missense |
probably benign |
|
|
R7154:Gapvd1
|
UTSW |
2 |
34,615,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7316:Gapvd1
|
UTSW |
2 |
34,594,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7358:Gapvd1
|
UTSW |
2 |
34,580,473 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7363:Gapvd1
|
UTSW |
2 |
34,602,207 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7371:Gapvd1
|
UTSW |
2 |
34,607,385 (GRCm39) |
missense |
probably benign |
|
|
R7418:Gapvd1
|
UTSW |
2 |
34,615,130 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7690:Gapvd1
|
UTSW |
2 |
34,619,134 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7740:Gapvd1
|
UTSW |
2 |
34,590,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7742:Gapvd1
|
UTSW |
2 |
34,568,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7857:Gapvd1
|
UTSW |
2 |
34,619,079 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8062:Gapvd1
|
UTSW |
2 |
34,568,126 (GRCm39) |
missense |
probably benign |
0.37 |
|
R8113:Gapvd1
|
UTSW |
2 |
34,594,330 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8303:Gapvd1
|
UTSW |
2 |
34,602,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8558:Gapvd1
|
UTSW |
2 |
34,594,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8751:Gapvd1
|
UTSW |
2 |
34,568,078 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8781:Gapvd1
|
UTSW |
2 |
34,610,698 (GRCm39) |
missense |
probably benign |
0.37 |
|
R8794:Gapvd1
|
UTSW |
2 |
34,594,330 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8876:Gapvd1
|
UTSW |
2 |
34,568,560 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8942:Gapvd1
|
UTSW |
2 |
34,619,134 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8954:Gapvd1
|
UTSW |
2 |
34,568,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9066:Gapvd1
|
UTSW |
2 |
34,617,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9428:Gapvd1
|
UTSW |
2 |
34,607,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9470:Gapvd1
|
UTSW |
2 |
34,602,280 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9505:Gapvd1
|
UTSW |
2 |
34,613,026 (GRCm39) |
missense |
|
|
|
R9690:Gapvd1
|
UTSW |
2 |
34,618,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Gapvd1
|
UTSW |
2 |
34,589,876 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
| Predicted Primers |
PCR Primer
(F):5'- CACTCTGACCGTGAATGTGAATG -3'
(R):5'- ATAGGAGGTTGACTGTAATTCCCC -3'
Sequencing Primer
(F):5'- CTCTGACCGTGAATGTGAATGGTAAC -3'
(R):5'- AGGTTGACTGTAATTCCCCTTTAG -3'
|
| Posted On |
2017-02-28 |
Incidental Mutation