Mutagenetix > Incidental Mutation

Incidental Mutation 'R4732:Pkd1l2'

470502

Institutional Source

Beutler Lab

Gene Symbol

Pkd1l2

Ensembl Gene

ENSMUSG00000034416

Gene Name

polycystic kidney disease 1 like 2

Synonyms

1700126L06Rik

MMRRC Submission

042022-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4732 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

117722418-117809188 bp(-) (GRCm39)

Type of Mutation

critical splice acceptor site

DNA Base Change (assembly)

T to A at 117722581 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000104721 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000040484] [ENSMUST00000098375] [ENSMUST00000109093]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000040484

SMART Domains

Protein: ENSMUSP00000037131
Gene: ENSMUSG00000034424

Domain	Start	End	E-Value	Type
Pfam:GCV_H	48	168	1.2e-51	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000098375

SMART Domains

Protein: ENSMUSP00000095977
Gene: ENSMUSG00000034416

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
CLECT	26	152	1.56e-21	SMART
Pfam:Gal_Lectin	168	250	1.8e-18	PFAM
PKD	260	341	3.84e-1	SMART
low complexity region	496	507	N/A	INTRINSIC
Pfam:REJ	510	886	1.8e-13	PFAM
low complexity region	1050	1060	N/A	INTRINSIC
GPS	1278	1327	1.61e-11	SMART
transmembrane domain	1346	1365	N/A	INTRINSIC
LH2	1390	1509	6.05e-13	SMART
transmembrane domain	1552	1574	N/A	INTRINSIC
transmembrane domain	1589	1611	N/A	INTRINSIC
transmembrane domain	1815	1837	N/A	INTRINSIC
transmembrane domain	1852	1874	N/A	INTRINSIC
transmembrane domain	1940	1962	N/A	INTRINSIC
Pfam:PKD_channel	1980	2403	6.4e-107	PFAM
Pfam:Ion_trans	2187	2396	2.5e-12	PFAM
low complexity region	2441	2458	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000109093

SMART Domains

Protein: ENSMUSP00000104721
Gene: ENSMUSG00000034416

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
CLECT	26	152	1.56e-21	SMART
Pfam:Gal_Lectin	168	250	6.9e-19	PFAM
PKD	260	341	3.84e-1	SMART
low complexity region	496	507	N/A	INTRINSIC
Pfam:REJ	519	883	7e-11	PFAM
low complexity region	1051	1061	N/A	INTRINSIC
GPS	1279	1328	1.61e-11	SMART
transmembrane domain	1347	1366	N/A	INTRINSIC
LH2	1391	1510	6.05e-13	SMART
transmembrane domain	1553	1575	N/A	INTRINSIC
transmembrane domain	1590	1612	N/A	INTRINSIC
transmembrane domain	1816	1838	N/A	INTRINSIC
transmembrane domain	1853	1875	N/A	INTRINSIC
transmembrane domain	1941	1963	N/A	INTRINSIC
Pfam:PKD_channel	1981	2403	5.9e-106	PFAM
Pfam:Ion_trans	2138	2409	3.4e-12	PFAM
low complexity region	2442	2459	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000162548

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.2%
20x: 95.1%

Validation Efficiency

99% (110/111)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. This gene appears to be a polymorphic pseudogene in humans, where some individuals contain a non-functional allele. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Allele List at MGI

Other mutations in this stock

Total: 192 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700128F08Rik	T	A	9: 8,222,174 (GRCm39)		noncoding transcript	Het
4933409G03Rik	A	G	2: 68,445,065 (GRCm39)		probably benign	Het
Acan	T	C	7: 78,748,357 (GRCm39)	S1043P	probably damaging	Het
Ackr2	A	G	9: 121,738,249 (GRCm39)	Y208C	probably damaging	Het
Actg1	C	T	11: 120,238,305 (GRCm39)		probably benign	Het
Actmap	T	A	7: 26,900,468 (GRCm39)	M149K	probably damaging	Het
Adam1a	T	A	5: 121,657,497 (GRCm39)	T599S	probably benign	Het
Adamts12	A	T	15: 11,270,748 (GRCm39)	S668C	probably damaging	Het
Adcy8	A	G	15: 64,626,711 (GRCm39)	V709A	possibly damaging	Het
Adgrf2	A	C	17: 43,021,645 (GRCm39)	I393S	probably damaging	Het
Ahnak	G	T	19: 8,984,665 (GRCm39)	G1983V	probably damaging	Het
Aim2	T	A	1: 173,291,442 (GRCm39)	D282E	possibly damaging	Het
Ak8	A	G	2: 28,650,083 (GRCm39)	Y370C	probably damaging	Het
Akap9	A	G	5: 4,063,901 (GRCm39)	D1750G	probably damaging	Het
Als2cl	T	A	9: 110,718,204 (GRCm39)	V315E	probably damaging	Het
Ankrd28	A	C	14: 31,477,698 (GRCm39)	C115G	probably benign	Het
Ap3b2	C	T	7: 81,121,680 (GRCm39)	A519T	probably damaging	Het
Apool	C	T	X: 111,281,897 (GRCm39)	T166I	probably damaging	Het
Arhgef2	A	T	3: 88,539,247 (GRCm39)	K65*	probably null	Het
Arhgef38	G	T	3: 132,838,030 (GRCm39)	Y633*	probably null	Het
Asah2	T	C	19: 31,972,758 (GRCm39)	N659S	probably benign	Het
Atf7ip2	A	G	16: 10,059,750 (GRCm39)	D430G	possibly damaging	Het
Atp8a1	G	A	5: 67,970,463 (GRCm39)	S92L	probably benign	Het
Bag4	C	T	8: 26,259,516 (GRCm39)	A228T	probably benign	Het
C130073F10Rik	C	A	4: 101,747,907 (GRCm39)	S89I	probably benign	Het
Cacna1g	T	C	11: 94,334,041 (GRCm39)	T867A	probably damaging	Het
Ccdc88a	T	G	11: 29,435,906 (GRCm39)	N1276K	probably benign	Het
Cdc42bpg	T	A	19: 6,361,221 (GRCm39)	V282E	probably damaging	Het
Cdipt	T	A	7: 126,577,530 (GRCm39)	L92H	probably damaging	Het
Celsr2	T	A	3: 108,306,268 (GRCm39)	D2012V	probably damaging	Het
Cenpt	A	G	8: 106,573,768 (GRCm39)	V254A	probably benign	Het
Cep104	T	A	4: 154,072,883 (GRCm39)	D380E	probably damaging	Het
Cers5	C	T	15: 99,639,518 (GRCm39)	R123Q	probably benign	Het
Ces2h	A	G	8: 105,741,236 (GRCm39)	E76G	probably damaging	Het
Cfap77	T	A	2: 28,874,400 (GRCm39)	E143D	probably benign	Het
Chmp7	C	A	14: 69,969,745 (GRCm39)	R65L	probably damaging	Het
Cldnd2	T	A	7: 43,091,613 (GRCm39)	C65S	possibly damaging	Het
Clec2g	C	A	6: 128,958,842 (GRCm39)	Y142*	probably null	Het
Coch	A	T	12: 51,651,802 (GRCm39)	E549V	probably benign	Het
Cog7	T	C	7: 121,563,467 (GRCm39)	D215G	probably benign	Het
Col4a2	T	C	8: 11,464,779 (GRCm39)	V348A	probably benign	Het
Col4a2	A	G	8: 11,496,197 (GRCm39)	H1606R	probably benign	Het
Cpd	T	C	11: 76,702,620 (GRCm39)	N583D	probably damaging	Het
Cyp2d11	T	A	15: 82,273,428 (GRCm39)	Y481F	probably benign	Het
D130043K22Rik	T	C	13: 25,083,648 (GRCm39)	S1038P	probably damaging	Het
Deptor	C	A	15: 55,044,406 (GRCm39)	H191N	probably benign	Het
Dgkz	A	T	2: 91,768,684 (GRCm39)	I699N	probably damaging	Het
Dnah12	C	T	14: 26,503,741 (GRCm39)	T1653I	probably damaging	Het
Dnah7c	T	A	1: 46,809,333 (GRCm39)	N3550K	probably damaging	Het
Dnah8	A	G	17: 30,994,035 (GRCm39)	K3384R	probably null	Het
Dnajc11	A	G	4: 152,055,424 (GRCm39)		probably benign	Het
Dnajc13	CT	C	9: 104,064,004 (GRCm39)		probably benign	Het
Dnhd1	C	A	7: 105,323,056 (GRCm39)	N521K	probably benign	Het
Drg2	T	C	11: 60,352,222 (GRCm39)		probably null	Het
Dync1h1	C	T	12: 110,615,941 (GRCm39)	Q3030*	probably null	Het
Efhb	G	A	17: 53,733,272 (GRCm39)	T533I	probably damaging	Het
Eif2d	T	C	1: 131,092,464 (GRCm39)	V374A	probably damaging	Het
Etfb	T	C	7: 43,093,624 (GRCm39)	V17A	probably damaging	Het
F5	C	T	1: 164,009,226 (GRCm39)	T332M	probably damaging	Het
Fcho1	T	C	8: 72,169,439 (GRCm39)	T156A	probably benign	Het
Fn1	A	T	1: 71,641,671 (GRCm39)		probably null	Het
Fnip2	A	T	3: 79,388,959 (GRCm39)	S561T	probably damaging	Het
Frs2	T	A	10: 116,909,998 (GRCm39)	T455S	probably benign	Het
Fry	G	A	5: 150,309,472 (GRCm39)	E639K		Het
Fto	T	A	8: 92,136,342 (GRCm39)	D205E	probably damaging	Het
Galnt2l	A	G	8: 122,997,013 (GRCm39)		probably benign	Het
Galntl6	G	A	8: 58,880,847 (GRCm39)	P147L	probably damaging	Het
Gigyf1	T	A	5: 137,523,032 (GRCm39)	D844E	probably benign	Het
Gle1	T	C	2: 29,830,244 (GRCm39)	S267P	probably damaging	Het
Glg1	G	A	8: 111,914,387 (GRCm39)	R466W	probably damaging	Het
Gm10277	T	C	11: 77,676,923 (GRCm39)		probably benign	Het
Gm6871	T	C	7: 41,196,173 (GRCm39)	I39V	probably benign	Het
Gm9970	A	G	5: 31,398,410 (GRCm39)		probably benign	Het
Gpr35	T	G	1: 92,911,107 (GRCm39)	I57S	probably damaging	Het
Gprin1	C	T	13: 54,887,770 (GRCm39)	G168E	possibly damaging	Het
Gtdc1	A	G	2: 44,679,067 (GRCm39)		probably benign	Het
Gtf3c2	G	T	5: 31,317,401 (GRCm39)	P586T	probably damaging	Het
Gucy1a2	A	T	9: 3,759,424 (GRCm39)	H410L	probably benign	Het
Gucy2c	A	G	6: 136,744,150 (GRCm39)	S150P	probably damaging	Het
Ifi214	T	C	1: 173,354,157 (GRCm39)	Q171R	probably benign	Het
Ifit1bl1	T	C	19: 34,571,721 (GRCm39)	I245M	probably benign	Het
Igkv4-50	T	C	6: 69,677,984 (GRCm39)	K40R	probably benign	Het
Igkv8-18	T	A	6: 70,333,280 (GRCm39)	I74N	probably damaging	Het
Il2ra	T	A	2: 11,681,731 (GRCm39)	M112K	probably benign	Het
Itpr2	A	G	6: 146,274,671 (GRCm39)	F837S	probably damaging	Het
Kbtbd7	T	C	14: 79,666,240 (GRCm39)	*691Q	probably null	Het
Kcnn2	T	A	18: 45,693,416 (GRCm39)	S331T	possibly damaging	Het
Khnyn	T	A	14: 56,123,946 (GRCm39)		probably null	Het
Kif26a	G	A	12: 112,142,007 (GRCm39)	A754T	probably benign	Het
Klra3	T	A	6: 130,304,095 (GRCm39)	Y199F	possibly damaging	Het
Lhx2	A	G	2: 38,250,003 (GRCm39)	K274R	probably damaging	Het
Lrp2	T	C	2: 69,363,899 (GRCm39)	I313V	probably benign	Het
Lrrfip1	A	T	1: 91,043,369 (GRCm39)	E591D	probably benign	Het
Lrrk2	A	C	15: 91,573,052 (GRCm39)	E200A	probably damaging	Het
Lrrk2	G	A	15: 91,649,950 (GRCm39)	E1696K	probably damaging	Het
Mast4	A	T	13: 102,909,080 (GRCm39)	M465K	probably damaging	Het
Moxd2	T	G	6: 40,855,793 (GRCm39)	I599L	probably benign	Het
Mug2	T	C	6: 122,048,831 (GRCm39)	S866P	probably damaging	Het
Ncam2	A	G	16: 81,231,772 (GRCm39)	T79A	possibly damaging	Het
Ncoa6	C	A	2: 155,263,221 (GRCm39)	Q404H	probably damaging	Het
Neb	A	G	2: 52,169,091 (GRCm39)	Y1815H	probably damaging	Het
Nell1	A	G	7: 50,505,965 (GRCm39)	D724G	probably damaging	Het
Nkx3-2	A	G	5: 41,919,487 (GRCm39)	V167A	probably benign	Het
Nsun3	C	A	16: 62,555,482 (GRCm39)	C348F	possibly damaging	Het
Obox6	A	T	7: 15,568,697 (GRCm39)	S60T	possibly damaging	Het
Oog2	T	A	4: 143,920,511 (GRCm39)		probably benign	Het
Or10g9b	A	T	9: 39,917,564 (GRCm39)	I227N	probably damaging	Het
Or11g2	T	A	14: 50,856,026 (GRCm39)	C116S	probably benign	Het
Or1ad6	G	A	11: 50,860,093 (GRCm39)	V83M	possibly damaging	Het
Or1e16	T	C	11: 73,286,521 (GRCm39)	D109G	probably benign	Het
Or2i1	T	C	17: 37,507,915 (GRCm39)	T315A	probably damaging	Het
Or2n1e	T	A	17: 38,586,438 (GRCm39)	Y259N	probably damaging	Het
Or9s18	T	C	13: 65,300,467 (GRCm39)	V143A	possibly damaging	Het
Pabpc1	A	T	15: 36,599,528 (GRCm39)	V389E	probably benign	Het
Pank4	A	T	4: 155,055,847 (GRCm39)	M291L	probably benign	Het
Pcf11	T	C	7: 92,308,041 (GRCm39)	D709G	probably benign	Het
Pcgf1	T	A	6: 83,056,938 (GRCm39)		probably benign	Het
Pcnx1	A	G	12: 82,042,525 (GRCm39)	I2256V	probably benign	Het
Pex6	A	G	17: 47,035,633 (GRCm39)		probably null	Het
Pex6	A	G	17: 47,033,214 (GRCm39)	D579G	probably benign	Het
Piezo2	C	T	18: 63,163,472 (GRCm39)	A2149T	probably damaging	Het
Pik3c2g	A	G	6: 139,881,711 (GRCm39)	E781G	probably benign	Het
Pik3r4	G	A	9: 105,555,375 (GRCm39)	V1111I	possibly damaging	Het
Plekhg1	T	A	10: 3,907,506 (GRCm39)	S808T	probably benign	Het
Pnkp	T	A	7: 44,509,878 (GRCm39)		probably benign	Het
Polr3c	A	T	3: 96,630,977 (GRCm39)	F148I	probably damaging	Het
Ppard	A	T	17: 28,505,417 (GRCm39)	T35S	probably benign	Het
Ptov1	T	C	7: 44,516,533 (GRCm39)	D134G	probably benign	Het
Ptprz1	T	A	6: 23,002,609 (GRCm39)	S1566R	probably benign	Het
Pum1	T	C	4: 130,445,504 (GRCm39)	S158P	probably benign	Het
Qki	T	C	17: 10,435,217 (GRCm39)	H269R	probably damaging	Het
Qrsl1	T	C	10: 43,752,659 (GRCm39)	Y388C	probably damaging	Het
Rapgef1	T	G	2: 29,579,172 (GRCm39)	I182S	probably damaging	Het
Ret	T	C	6: 118,140,154 (GRCm39)	S1013G	possibly damaging	Het
Rimbp3	A	G	16: 17,028,465 (GRCm39)	R630G	possibly damaging	Het
Rnmt	A	T	18: 68,451,031 (GRCm39)		probably benign	Het
Ryr2	A	T	13: 11,592,795 (GRCm39)	M4653K	possibly damaging	Het
Sacm1l	G	A	9: 123,419,895 (GRCm39)	V553I	probably benign	Het
Sec31b	A	T	19: 44,521,116 (GRCm39)	S110T	probably damaging	Het
Serpina3k	G	A	12: 104,307,119 (GRCm39)	G117D	probably damaging	Het
Sesn2	T	C	4: 132,221,902 (GRCm39)	Y410C	probably damaging	Het
Slc24a1	G	A	9: 64,856,836 (GRCm39)	R24C	probably benign	Het
Slc35g2	A	C	9: 100,434,555 (GRCm39)	V372G	probably benign	Het
Slc7a7	T	C	14: 54,646,190 (GRCm39)	Y91C	probably damaging	Het
Slc7a9	T	A	7: 35,152,988 (GRCm39)	Y135*	probably null	Het
Slco1a7	A	T	6: 141,668,905 (GRCm39)	M509K	probably benign	Het
Slco4a1	A	G	2: 180,115,408 (GRCm39)	N662D	probably damaging	Het
Slfn4	T	A	11: 83,080,108 (GRCm39)		probably benign	Het
Slmap	T	C	14: 26,189,690 (GRCm39)	N156S	probably damaging	Het
Smim29	A	G	17: 27,784,244 (GRCm39)		probably benign	Het
Snx18	A	G	13: 113,754,310 (GRCm39)	S208P	probably benign	Het
Sorbs1	T	A	19: 40,303,133 (GRCm39)	R485S	probably benign	Het
Spib	A	G	7: 44,178,309 (GRCm39)	S154P	probably damaging	Het
Spty2d1	T	C	7: 46,645,858 (GRCm39)	D595G	probably damaging	Het
St7	T	A	6: 17,906,515 (GRCm39)		probably null	Het
Susd1	T	C	4: 59,428,029 (GRCm39)	T52A	possibly damaging	Het
Svs5	T	A	2: 164,079,043 (GRCm39)	D288V	possibly damaging	Het
Syt7	T	A	19: 10,420,288 (GRCm39)	I355N	probably damaging	Het
Tarm1	G	A	7: 3,545,416 (GRCm39)	Q145*	probably null	Het
Teddm2	T	A	1: 153,726,487 (GRCm39)	E76V	probably damaging	Het
Thsd7b	T	C	1: 129,540,923 (GRCm39)	S343P	probably damaging	Het
Tigd2	T	A	6: 59,188,400 (GRCm39)	H422Q	probably benign	Het
Tle1	T	C	4: 72,043,256 (GRCm39)	N538D	possibly damaging	Het
Tmc2	A	G	2: 130,103,317 (GRCm39)		probably null	Het
Tmtc1	A	C	6: 148,186,478 (GRCm39)		probably null	Het
Tns3	C	T	11: 8,400,986 (GRCm39)	R1104H	probably benign	Het
Trim6	T	C	7: 103,881,855 (GRCm39)	Y369H	probably damaging	Het
Triobp	G	A	15: 78,851,313 (GRCm39)	R489K	probably damaging	Het
Trpv4	T	C	5: 114,760,814 (GRCm39)	D732G	possibly damaging	Het
Trrap	G	A	5: 144,753,380 (GRCm39)	V1883I	probably damaging	Het
Tsc2	C	A	17: 24,822,249 (GRCm39)	V1141F	possibly damaging	Het
Ttn	A	G	2: 76,730,171 (GRCm39)		probably benign	Het
Ttn	A	T	2: 76,773,355 (GRCm39)	M2395K	unknown	Het
Tyrp1	A	T	4: 80,763,172 (GRCm39)	D353V	possibly damaging	Het
Ubd	A	C	17: 37,506,593 (GRCm39)	T160P	probably benign	Het
Ugt2b36	G	T	5: 87,229,397 (GRCm39)	Y156*	probably null	Het
Ulk4	G	A	9: 121,092,704 (GRCm39)	R178*	probably null	Het
Unc13d	A	G	11: 115,964,408 (GRCm39)	V312A	possibly damaging	Het
Urb2	G	T	8: 124,755,636 (GRCm39)	A448S	probably damaging	Het
Urod	G	A	4: 116,848,870 (GRCm39)	A92V	possibly damaging	Het
Vmn1r33	T	A	6: 66,588,803 (GRCm39)	R250S	probably benign	Het
Vmn1r87	A	T	7: 12,866,254 (GRCm39)	M11K	possibly damaging	Het
Vmn2r77	C	T	7: 86,450,195 (GRCm39)	T147I	probably benign	Het
Vstm4	A	G	14: 32,639,859 (GRCm39)	K96E	possibly damaging	Het
Vxn	T	C	1: 9,677,201 (GRCm39)	S24P	probably benign	Het
Washc4	A	T	10: 83,410,343 (GRCm39)	M644L	probably benign	Het
Wwp1	T	C	4: 19,661,990 (GRCm39)	D172G	probably benign	Het
Zbtb38	A	T	9: 96,569,737 (GRCm39)	V449E	probably damaging	Het
Zfhx4	T	C	3: 5,279,867 (GRCm39)		probably benign	Het
Zfp229	C	T	17: 21,964,267 (GRCm39)	H166Y	possibly damaging	Het
Zfp512b	A	G	2: 181,230,532 (GRCm39)	S453P	probably benign	Het
Zp2	C	A	7: 119,737,343 (GRCm39)	V282L	probably damaging	Het

Other mutations in Pkd1l2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01338:Pkd1l2	APN	8	117,786,259 (GRCm39)	nonsense	probably null
IGL01353:Pkd1l2	APN	8	117,784,182 (GRCm39)	missense	probably benign	0.24
IGL01362:Pkd1l2	APN	8	117,748,595 (GRCm39)	missense	probably damaging	1.00
IGL01486:Pkd1l2	APN	8	117,786,331 (GRCm39)	missense	probably benign
IGL01672:Pkd1l2	APN	8	117,807,471 (GRCm39)	missense	possibly damaging	0.94
IGL01696:Pkd1l2	APN	8	117,783,126 (GRCm39)	missense	probably benign	0.12
IGL01819:Pkd1l2	APN	8	117,724,913 (GRCm39)	missense	probably damaging	1.00
IGL01833:Pkd1l2	APN	8	117,787,264 (GRCm39)	missense	probably benign	0.00
IGL01981:Pkd1l2	APN	8	117,743,655 (GRCm39)	missense	probably benign	0.04
IGL02066:Pkd1l2	APN	8	117,736,303 (GRCm39)	splice site	probably benign
IGL02381:Pkd1l2	APN	8	117,762,539 (GRCm39)	splice site	probably benign
IGL02416:Pkd1l2	APN	8	117,767,574 (GRCm39)	missense	possibly damaging	0.82
IGL02736:Pkd1l2	APN	8	117,767,405 (GRCm39)	missense	probably benign	0.00
IGL02828:Pkd1l2	APN	8	117,756,298 (GRCm39)	missense	probably benign
IGL02861:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL02862:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL02883:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL02884:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL02894:Pkd1l2	APN	8	117,740,630 (GRCm39)	missense	probably damaging	0.97
IGL02900:Pkd1l2	APN	8	117,750,830 (GRCm39)	missense	probably benign	0.03
IGL02901:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL02929:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL02941:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL02957:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL02969:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03028:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03059:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03065:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03066:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03083:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03084:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03124:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03162:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03165:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03335:Pkd1l2	APN	8	117,792,484 (GRCm39)	missense	probably benign	0.07
IGL03357:Pkd1l2	APN	8	117,722,548 (GRCm39)	missense	probably damaging	1.00
IGL02835:Pkd1l2	UTSW	8	117,792,484 (GRCm39)	missense	probably benign	0.07
PIT4453001:Pkd1l2	UTSW	8	117,748,761 (GRCm39)	missense	probably benign	0.00
R0127:Pkd1l2	UTSW	8	117,776,787 (GRCm39)	splice site	probably benign
R0309:Pkd1l2	UTSW	8	117,724,315 (GRCm39)	missense	probably damaging	0.99
R0365:Pkd1l2	UTSW	8	117,748,589 (GRCm39)	missense	probably benign	0.02
R0526:Pkd1l2	UTSW	8	117,808,999 (GRCm39)	missense	probably damaging	1.00
R0571:Pkd1l2	UTSW	8	117,808,957 (GRCm39)	missense	probably benign	0.01
R0716:Pkd1l2	UTSW	8	117,777,839 (GRCm39)	missense	probably damaging	1.00
R0787:Pkd1l2	UTSW	8	117,802,916 (GRCm39)	missense	possibly damaging	0.90
R0893:Pkd1l2	UTSW	8	117,771,231 (GRCm39)	missense	probably damaging	0.99
R1256:Pkd1l2	UTSW	8	117,746,282 (GRCm39)	critical splice acceptor site	probably null
R1391:Pkd1l2	UTSW	8	117,781,673 (GRCm39)	missense	possibly damaging	0.87
R1474:Pkd1l2	UTSW	8	117,792,236 (GRCm39)	splice site	probably benign
R1491:Pkd1l2	UTSW	8	117,755,147 (GRCm39)	missense	probably damaging	1.00
R1520:Pkd1l2	UTSW	8	117,772,898 (GRCm39)	missense	probably benign	0.00
R1521:Pkd1l2	UTSW	8	117,792,239 (GRCm39)	splice site	probably null
R1544:Pkd1l2	UTSW	8	117,764,974 (GRCm39)	frame shift	probably null
R1558:Pkd1l2	UTSW	8	117,808,991 (GRCm39)	missense	possibly damaging	0.94
R1673:Pkd1l2	UTSW	8	117,767,514 (GRCm39)	missense	probably benign	0.00
R1691:Pkd1l2	UTSW	8	117,783,158 (GRCm39)	missense	possibly damaging	0.60
R1754:Pkd1l2	UTSW	8	117,757,458 (GRCm39)	missense	possibly damaging	0.81
R1857:Pkd1l2	UTSW	8	117,767,408 (GRCm39)	missense	possibly damaging	0.70
R1939:Pkd1l2	UTSW	8	117,772,921 (GRCm39)	nonsense	probably null
R1955:Pkd1l2	UTSW	8	117,770,100 (GRCm39)	missense	probably benign
R1957:Pkd1l2	UTSW	8	117,757,421 (GRCm39)	missense	probably damaging	1.00
R1959:Pkd1l2	UTSW	8	117,769,970 (GRCm39)	critical splice donor site	probably null
R2024:Pkd1l2	UTSW	8	117,746,272 (GRCm39)	missense	probably benign
R2046:Pkd1l2	UTSW	8	117,726,694 (GRCm39)	missense	probably damaging	1.00
R2102:Pkd1l2	UTSW	8	117,808,208 (GRCm39)	missense	probably damaging	0.98
R2116:Pkd1l2	UTSW	8	117,757,461 (GRCm39)	missense	possibly damaging	0.93
R2148:Pkd1l2	UTSW	8	117,783,064 (GRCm39)	missense	probably damaging	0.98
R2251:Pkd1l2	UTSW	8	117,784,177 (GRCm39)	missense	probably damaging	1.00
R2252:Pkd1l2	UTSW	8	117,784,177 (GRCm39)	missense	probably damaging	1.00
R2366:Pkd1l2	UTSW	8	117,770,056 (GRCm39)	missense	probably benign	0.01
R2566:Pkd1l2	UTSW	8	117,746,233 (GRCm39)	missense	probably damaging	1.00
R2872:Pkd1l2	UTSW	8	117,764,903 (GRCm39)	missense	probably benign	0.10
R2872:Pkd1l2	UTSW	8	117,764,903 (GRCm39)	missense	probably benign	0.10
R2985:Pkd1l2	UTSW	8	117,792,290 (GRCm39)	missense	probably benign	0.00
R3055:Pkd1l2	UTSW	8	117,795,054 (GRCm39)	critical splice acceptor site	probably null
R3436:Pkd1l2	UTSW	8	117,767,478 (GRCm39)	missense	probably benign	0.01
R4733:Pkd1l2	UTSW	8	117,722,581 (GRCm39)	critical splice acceptor site	probably null
R4763:Pkd1l2	UTSW	8	117,746,168 (GRCm39)	missense	probably damaging	0.96
R4789:Pkd1l2	UTSW	8	117,738,314 (GRCm39)	missense	probably damaging	0.99
R4921:Pkd1l2	UTSW	8	117,781,624 (GRCm39)	missense	probably benign	0.03
R4921:Pkd1l2	UTSW	8	117,799,288 (GRCm39)	missense	probably damaging	0.97
R4999:Pkd1l2	UTSW	8	117,774,113 (GRCm39)	splice site	probably null
R5057:Pkd1l2	UTSW	8	117,781,747 (GRCm39)	missense	probably benign	0.21
R5209:Pkd1l2	UTSW	8	117,783,181 (GRCm39)	missense	probably benign	0.23
R5241:Pkd1l2	UTSW	8	117,761,857 (GRCm39)	missense	probably damaging	1.00
R5480:Pkd1l2	UTSW	8	117,757,388 (GRCm39)	missense	probably damaging	0.99
R5501:Pkd1l2	UTSW	8	117,792,569 (GRCm39)	missense	probably damaging	0.98
R5533:Pkd1l2	UTSW	8	117,794,855 (GRCm39)	missense	probably benign	0.03
R5582:Pkd1l2	UTSW	8	117,767,522 (GRCm39)	nonsense	probably null
R5610:Pkd1l2	UTSW	8	117,769,059 (GRCm39)	missense	probably benign	0.04
R5770:Pkd1l2	UTSW	8	117,781,757 (GRCm39)	missense	probably damaging	1.00
R5854:Pkd1l2	UTSW	8	117,792,485 (GRCm39)	missense	possibly damaging	0.48
R5867:Pkd1l2	UTSW	8	117,781,750 (GRCm39)	missense	probably damaging	0.96
R5881:Pkd1l2	UTSW	8	117,724,321 (GRCm39)	missense	probably damaging	0.99
R5906:Pkd1l2	UTSW	8	117,756,387 (GRCm39)	missense	probably damaging	1.00
R5909:Pkd1l2	UTSW	8	117,750,795 (GRCm39)	missense	probably benign	0.00
R6030:Pkd1l2	UTSW	8	117,769,976 (GRCm39)	missense	probably damaging	1.00
R6030:Pkd1l2	UTSW	8	117,769,976 (GRCm39)	missense	probably damaging	1.00
R6084:Pkd1l2	UTSW	8	117,740,726 (GRCm39)	missense	probably damaging	1.00
R6122:Pkd1l2	UTSW	8	117,809,107 (GRCm39)	missense	probably benign	0.02
R6216:Pkd1l2	UTSW	8	117,808,209 (GRCm39)	missense	probably damaging	1.00
R6406:Pkd1l2	UTSW	8	117,762,586 (GRCm39)	missense	probably damaging	0.99
R6417:Pkd1l2	UTSW	8	117,740,638 (GRCm39)	missense	probably damaging	1.00
R6420:Pkd1l2	UTSW	8	117,740,638 (GRCm39)	missense	probably damaging	1.00
R6601:Pkd1l2	UTSW	8	117,767,405 (GRCm39)	missense	probably benign	0.00
R6743:Pkd1l2	UTSW	8	117,757,370 (GRCm39)	missense	probably damaging	1.00
R7053:Pkd1l2	UTSW	8	117,740,681 (GRCm39)	missense	probably damaging	1.00
R7144:Pkd1l2	UTSW	8	117,802,870 (GRCm39)	nonsense	probably null
R7148:Pkd1l2	UTSW	8	117,807,525 (GRCm39)	missense	probably benign	0.00
R7169:Pkd1l2	UTSW	8	117,767,574 (GRCm39)	missense	possibly damaging	0.82
R7217:Pkd1l2	UTSW	8	117,722,536 (GRCm39)	missense	probably benign	0.24
R7310:Pkd1l2	UTSW	8	117,750,773 (GRCm39)	missense	probably benign
R7382:Pkd1l2	UTSW	8	117,781,610 (GRCm39)	missense	possibly damaging	0.95
R7397:Pkd1l2	UTSW	8	117,762,641 (GRCm39)	missense	possibly damaging	0.94
R7408:Pkd1l2	UTSW	8	117,755,218 (GRCm39)	missense	possibly damaging	0.77
R7437:Pkd1l2	UTSW	8	117,757,421 (GRCm39)	missense	probably damaging	0.96
R7492:Pkd1l2	UTSW	8	117,794,849 (GRCm39)	missense	probably damaging	1.00
R7496:Pkd1l2	UTSW	8	117,787,333 (GRCm39)	missense	possibly damaging	0.89
R7519:Pkd1l2	UTSW	8	117,792,268 (GRCm39)	missense	probably benign
R7590:Pkd1l2	UTSW	8	117,807,525 (GRCm39)	missense	probably benign	0.00
R7623:Pkd1l2	UTSW	8	117,756,384 (GRCm39)	missense	probably damaging	1.00
R7768:Pkd1l2	UTSW	8	117,781,599 (GRCm39)	critical splice donor site	probably null
R7897:Pkd1l2	UTSW	8	117,724,827 (GRCm39)	missense	possibly damaging	0.69
R7982:Pkd1l2	UTSW	8	117,777,926 (GRCm39)	missense	possibly damaging	0.70
R8024:Pkd1l2	UTSW	8	117,802,921 (GRCm39)	missense	possibly damaging	0.85
R8140:Pkd1l2	UTSW	8	117,774,236 (GRCm39)	missense	probably benign
R8145:Pkd1l2	UTSW	8	117,781,742 (GRCm39)	missense	probably benign
R8228:Pkd1l2	UTSW	8	117,792,514 (GRCm39)	missense	probably damaging	0.97
R8252:Pkd1l2	UTSW	8	117,767,472 (GRCm39)	missense	probably benign	0.29
R8500:Pkd1l2	UTSW	8	117,774,302 (GRCm39)	critical splice acceptor site	probably null
R8732:Pkd1l2	UTSW	8	117,792,311 (GRCm39)	missense	probably benign	0.28
R8809:Pkd1l2	UTSW	8	117,726,660 (GRCm39)	missense	probably damaging	1.00
R8896:Pkd1l2	UTSW	8	117,740,615 (GRCm39)	missense	possibly damaging	0.91
R8961:Pkd1l2	UTSW	8	117,726,717 (GRCm39)	missense	possibly damaging	0.52
R8985:Pkd1l2	UTSW	8	117,764,849 (GRCm39)	missense	probably benign	0.01
R9008:Pkd1l2	UTSW	8	117,769,037 (GRCm39)	missense	probably benign	0.32
R9091:Pkd1l2	UTSW	8	117,759,433 (GRCm39)	missense	probably damaging	1.00
R9138:Pkd1l2	UTSW	8	117,781,748 (GRCm39)	missense	probably benign	0.43
R9160:Pkd1l2	UTSW	8	117,767,408 (GRCm39)	missense	possibly damaging	0.70
R9249:Pkd1l2	UTSW	8	117,746,159 (GRCm39)	missense	probably damaging	0.99
R9270:Pkd1l2	UTSW	8	117,759,433 (GRCm39)	missense	probably damaging	1.00
R9735:Pkd1l2	UTSW	8	117,772,820 (GRCm39)	missense	possibly damaging	0.94
Z1176:Pkd1l2	UTSW	8	117,781,653 (GRCm39)	missense	probably damaging	1.00
Z1177:Pkd1l2	UTSW	8	117,757,430 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

Posted On

2017-03-08