Incidental Mutation 'R0499:Dop1b'
| ID |
47062 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dop1b
|
| Ensembl Gene |
ENSMUSG00000022946 |
| Gene Name |
DOP1 leucine zipper like protein B |
| Synonyms |
Dopey2, 0610038M01Rik, 2610510B01Rik |
| MMRRC Submission |
038695-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0499 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
93508795-93607476 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 93567325 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Serine
at position 1251
(T1251S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000154771
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045004]
[ENSMUST00000227156]
|
| AlphaFold |
Q3UHQ6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000045004
AA Change: T1369S
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000044437
Gene: ENSMUSG00000022946
AA Change: T1369S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Dopey_N
|
11 |
308 |
3.9e-104 |
PFAM |
|
low complexity region
|
651 |
666 |
N/A |
INTRINSIC |
|
low complexity region
|
709 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
747 |
759 |
N/A |
INTRINSIC |
|
low complexity region
|
1186 |
1199 |
N/A |
INTRINSIC |
|
low complexity region
|
1436 |
1451 |
N/A |
INTRINSIC |
|
low complexity region
|
1893 |
1908 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000226215
AA Change: T579S
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000226535
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000226836
AA Change: T531S
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000227156
AA Change: T1251S
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.2%
|
| Validation Efficiency |
99% (97/98) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acad9 |
T |
C |
3: 36,139,564 (GRCm39) |
V388A |
probably damaging |
Het |
| Acp3 |
T |
C |
9: 104,197,201 (GRCm39) |
E146G |
probably damaging |
Het |
| Adap2 |
A |
T |
11: 80,066,905 (GRCm39) |
R276S |
probably damaging |
Het |
| Agbl3 |
A |
T |
6: 34,816,270 (GRCm39) |
M727L |
probably benign |
Het |
| Ahnak |
T |
A |
19: 8,977,628 (GRCm39) |
|
probably benign |
Het |
| Ankmy1 |
G |
T |
1: 92,813,948 (GRCm39) |
D410E |
probably damaging |
Het |
| Ankra2 |
T |
C |
13: 98,402,962 (GRCm39) |
S70P |
probably damaging |
Het |
| Aox4 |
T |
C |
1: 58,302,556 (GRCm39) |
|
probably null |
Het |
| Arl13b |
G |
A |
16: 62,622,096 (GRCm39) |
T399I |
probably benign |
Het |
| Atad2 |
A |
T |
15: 57,966,636 (GRCm39) |
D652E |
possibly damaging |
Het |
| Atad2 |
T |
G |
15: 57,984,345 (GRCm39) |
M328L |
probably benign |
Het |
| Ccnb1 |
T |
C |
13: 100,916,642 (GRCm39) |
|
probably null |
Het |
| Ccr2 |
G |
C |
9: 123,905,976 (GRCm39) |
K85N |
possibly damaging |
Het |
| Ccr2 |
A |
T |
9: 123,906,163 (GRCm39) |
T148S |
possibly damaging |
Het |
| Cdc20b |
T |
C |
13: 113,192,484 (GRCm39) |
V59A |
probably benign |
Het |
| Cdin1 |
C |
T |
2: 115,473,172 (GRCm39) |
R101W |
probably damaging |
Het |
| Cdkl3 |
T |
C |
11: 51,923,243 (GRCm39) |
S507P |
possibly damaging |
Het |
| Celf6 |
C |
A |
9: 59,510,161 (GRCm39) |
T86K |
probably benign |
Het |
| Ces1g |
A |
G |
8: 94,060,317 (GRCm39) |
F101L |
probably benign |
Het |
| Cimap1d |
T |
C |
10: 79,476,099 (GRCm39) |
D155G |
probably damaging |
Het |
| Cntnap3 |
C |
T |
13: 65,006,492 (GRCm39) |
D107N |
probably benign |
Het |
| Col15a1 |
A |
T |
4: 47,262,950 (GRCm39) |
D534V |
probably damaging |
Het |
| Col27a1 |
A |
G |
4: 63,218,978 (GRCm39) |
|
probably benign |
Het |
| Csmd3 |
T |
C |
15: 47,710,527 (GRCm39) |
T1687A |
probably benign |
Het |
| Cstf3 |
A |
G |
2: 104,479,950 (GRCm39) |
I272M |
possibly damaging |
Het |
| Cyp2d40 |
T |
C |
15: 82,645,418 (GRCm39) |
T150A |
probably benign |
Het |
| Dnah8 |
T |
A |
17: 30,934,483 (GRCm39) |
F1489L |
possibly damaging |
Het |
| Dtx2 |
G |
A |
5: 136,057,957 (GRCm39) |
G421R |
probably damaging |
Het |
| Epb41l3 |
T |
A |
17: 69,554,654 (GRCm39) |
D251E |
probably benign |
Het |
| Erg |
A |
C |
16: 95,161,842 (GRCm39) |
Y305* |
probably null |
Het |
| Exosc4 |
G |
A |
15: 76,213,766 (GRCm39) |
A197T |
probably benign |
Het |
| Fam227b |
T |
A |
2: 125,942,829 (GRCm39) |
I323L |
probably benign |
Het |
| Far1 |
G |
T |
7: 113,153,503 (GRCm39) |
|
probably benign |
Het |
| Fmod |
A |
G |
1: 133,968,934 (GRCm39) |
I325V |
possibly damaging |
Het |
| Fshr |
C |
G |
17: 89,316,713 (GRCm39) |
S169T |
probably benign |
Het |
| Gm4076 |
G |
T |
13: 85,275,345 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5134 |
A |
T |
10: 75,828,359 (GRCm39) |
Y313F |
probably benign |
Het |
| H2-Q6 |
T |
A |
17: 35,644,179 (GRCm39) |
F54I |
probably damaging |
Het |
| Hcrtr2 |
C |
A |
9: 76,161,954 (GRCm39) |
L145F |
probably damaging |
Het |
| Hepacam2 |
A |
G |
6: 3,476,121 (GRCm39) |
L268P |
probably damaging |
Het |
| Herc2 |
C |
A |
7: 55,834,117 (GRCm39) |
C3107* |
probably null |
Het |
| Herc4 |
T |
C |
10: 63,099,811 (GRCm39) |
V78A |
probably damaging |
Het |
| Hyal5 |
T |
C |
6: 24,877,920 (GRCm39) |
W339R |
probably damaging |
Het |
| Igfbp6 |
T |
A |
15: 102,056,419 (GRCm39) |
|
probably null |
Het |
| Il18rap |
A |
T |
1: 40,564,218 (GRCm39) |
H112L |
probably benign |
Het |
| Il1r2 |
T |
A |
1: 40,162,309 (GRCm39) |
Y317* |
probably null |
Het |
| Ints8 |
C |
A |
4: 11,246,097 (GRCm39) |
V190L |
probably benign |
Het |
| Ipo11 |
T |
C |
13: 107,061,595 (GRCm39) |
T22A |
probably benign |
Het |
| Itgb4 |
C |
A |
11: 115,870,521 (GRCm39) |
R117S |
probably benign |
Het |
| Lcorl |
C |
G |
5: 45,891,711 (GRCm39) |
G214A |
probably benign |
Het |
| Lgals3bp |
T |
A |
11: 118,289,019 (GRCm39) |
|
probably null |
Het |
| Lyst |
T |
A |
13: 13,791,298 (GRCm39) |
L54I |
probably damaging |
Het |
| Mcm9 |
T |
C |
10: 53,414,250 (GRCm39) |
T1015A |
probably benign |
Het |
| Mef2d |
T |
A |
3: 88,063,825 (GRCm39) |
I84N |
probably damaging |
Het |
| Mmrn2 |
A |
G |
14: 34,119,913 (GRCm39) |
N261S |
probably damaging |
Het |
| Mpdz |
T |
C |
4: 81,210,768 (GRCm39) |
T1693A |
probably benign |
Het |
| Mss51 |
T |
A |
14: 20,534,756 (GRCm39) |
Q338L |
possibly damaging |
Het |
| Mstn |
T |
A |
1: 53,103,143 (GRCm39) |
Y160N |
probably damaging |
Het |
| Muc6 |
T |
C |
7: 141,226,735 (GRCm39) |
T1431A |
probably benign |
Het |
| Nek9 |
A |
T |
12: 85,348,657 (GRCm39) |
M959K |
probably benign |
Het |
| Or2ak6 |
G |
A |
11: 58,593,069 (GRCm39) |
V181I |
probably benign |
Het |
| Or4f58 |
A |
T |
2: 111,851,777 (GRCm39) |
C141S |
probably damaging |
Het |
| Or8b47 |
A |
T |
9: 38,435,801 (GRCm39) |
M258L |
probably benign |
Het |
| Otog |
G |
T |
7: 45,923,256 (GRCm39) |
G1044W |
probably damaging |
Het |
| Pcdh9 |
G |
A |
14: 94,123,671 (GRCm39) |
T833M |
probably damaging |
Het |
| Pdcd10 |
T |
C |
3: 75,434,958 (GRCm39) |
K111R |
probably damaging |
Het |
| Pde5a |
A |
G |
3: 122,542,107 (GRCm39) |
N199S |
probably damaging |
Het |
| Plekhg1 |
T |
C |
10: 3,887,971 (GRCm39) |
V355A |
probably damaging |
Het |
| Podn |
G |
T |
4: 107,878,791 (GRCm39) |
L359I |
probably damaging |
Het |
| Psd |
T |
C |
19: 46,310,600 (GRCm39) |
E483G |
probably damaging |
Het |
| Ptch2 |
T |
A |
4: 116,968,340 (GRCm39) |
L905* |
probably null |
Het |
| Rxfp2 |
T |
A |
5: 149,989,880 (GRCm39) |
N420K |
probably damaging |
Het |
| Scpppq1 |
C |
A |
5: 104,222,747 (GRCm39) |
G24* |
probably null |
Het |
| Sde2 |
T |
A |
1: 180,689,992 (GRCm39) |
D237E |
probably benign |
Het |
| Serpina1d |
A |
T |
12: 103,732,016 (GRCm39) |
L281Q |
probably damaging |
Het |
| Serpina9 |
T |
C |
12: 103,967,729 (GRCm39) |
N222S |
probably benign |
Het |
| Sh3bgrl2 |
A |
G |
9: 83,459,612 (GRCm39) |
K57E |
probably damaging |
Het |
| Shc3 |
C |
T |
13: 51,634,264 (GRCm39) |
|
probably benign |
Het |
| Sik3 |
T |
C |
9: 46,120,038 (GRCm39) |
M659T |
possibly damaging |
Het |
| Slc23a2 |
A |
G |
2: 131,913,937 (GRCm39) |
L280P |
probably damaging |
Het |
| Smchd1 |
G |
T |
17: 71,694,083 (GRCm39) |
Q1221K |
probably benign |
Het |
| Spmip2 |
T |
A |
3: 79,313,093 (GRCm39) |
W56R |
probably damaging |
Het |
| Spocd1 |
A |
G |
4: 129,849,263 (GRCm39) |
N694S |
possibly damaging |
Het |
| Styxl2 |
C |
A |
1: 165,926,670 (GRCm39) |
V981L |
probably benign |
Het |
| Tecta |
T |
C |
9: 42,263,359 (GRCm39) |
D1409G |
probably damaging |
Het |
| Tmem131 |
A |
T |
1: 36,880,754 (GRCm39) |
V172D |
probably damaging |
Het |
| Trpm3 |
T |
C |
19: 22,964,237 (GRCm39) |
M1244T |
possibly damaging |
Het |
| Ugcg |
G |
C |
4: 59,217,036 (GRCm39) |
V187L |
possibly damaging |
Het |
| Usp17le |
T |
C |
7: 104,417,708 (GRCm39) |
N478S |
probably benign |
Het |
| Usp36 |
A |
G |
11: 118,164,397 (GRCm39) |
V205A |
probably damaging |
Het |
| Vmn1r25 |
T |
A |
6: 57,955,494 (GRCm39) |
Q265L |
probably damaging |
Het |
| Vwf |
A |
T |
6: 125,615,077 (GRCm39) |
H1176L |
probably benign |
Het |
| Zfyve28 |
C |
T |
5: 34,389,550 (GRCm39) |
D217N |
possibly damaging |
Het |
| Zranb3 |
A |
C |
1: 127,882,817 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Dop1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dop1b
|
APN |
16 |
93,596,914 (GRCm39) |
unclassified |
probably benign |
|
|
IGL00492:Dop1b
|
APN |
16 |
93,577,670 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00753:Dop1b
|
APN |
16 |
93,566,512 (GRCm39) |
missense |
probably benign |
|
|
IGL00832:Dop1b
|
APN |
16 |
93,560,289 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00939:Dop1b
|
APN |
16 |
93,570,971 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL01019:Dop1b
|
APN |
16 |
93,607,117 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL01288:Dop1b
|
APN |
16 |
93,536,181 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL01505:Dop1b
|
APN |
16 |
93,554,004 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01535:Dop1b
|
APN |
16 |
93,566,846 (GRCm39) |
nonsense |
probably null |
|
|
IGL01696:Dop1b
|
APN |
16 |
93,567,128 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02077:Dop1b
|
APN |
16 |
93,577,648 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02163:Dop1b
|
APN |
16 |
93,559,315 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02234:Dop1b
|
APN |
16 |
93,549,039 (GRCm39) |
missense |
probably benign |
|
|
IGL02302:Dop1b
|
APN |
16 |
93,607,005 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL02485:Dop1b
|
APN |
16 |
93,567,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02563:Dop1b
|
APN |
16 |
93,574,293 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02733:Dop1b
|
APN |
16 |
93,536,079 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02792:Dop1b
|
APN |
16 |
93,598,460 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL02941:Dop1b
|
APN |
16 |
93,552,361 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03143:Dop1b
|
APN |
16 |
93,556,543 (GRCm39) |
missense |
probably benign |
|
|
PIT4519001:Dop1b
|
UTSW |
16 |
93,558,942 (GRCm39) |
missense |
probably benign |
|
|
R0320:Dop1b
|
UTSW |
16 |
93,607,035 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0501:Dop1b
|
UTSW |
16 |
93,549,750 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0534:Dop1b
|
UTSW |
16 |
93,559,393 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0583:Dop1b
|
UTSW |
16 |
93,552,374 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0626:Dop1b
|
UTSW |
16 |
93,560,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0724:Dop1b
|
UTSW |
16 |
93,559,213 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0907:Dop1b
|
UTSW |
16 |
93,598,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1263:Dop1b
|
UTSW |
16 |
93,574,274 (GRCm39) |
missense |
probably benign |
|
|
R1378:Dop1b
|
UTSW |
16 |
93,567,280 (GRCm39) |
missense |
probably benign |
|
|
R1572:Dop1b
|
UTSW |
16 |
93,567,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1604:Dop1b
|
UTSW |
16 |
93,559,458 (GRCm39) |
missense |
probably benign |
|
|
R1642:Dop1b
|
UTSW |
16 |
93,559,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1668:Dop1b
|
UTSW |
16 |
93,562,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1669:Dop1b
|
UTSW |
16 |
93,566,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1702:Dop1b
|
UTSW |
16 |
93,544,509 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1711:Dop1b
|
UTSW |
16 |
93,596,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1917:Dop1b
|
UTSW |
16 |
93,513,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Dop1b
|
UTSW |
16 |
93,579,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1988:Dop1b
|
UTSW |
16 |
93,563,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2029:Dop1b
|
UTSW |
16 |
93,566,323 (GRCm39) |
missense |
probably benign |
0.36 |
|
R2139:Dop1b
|
UTSW |
16 |
93,567,895 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R2355:Dop1b
|
UTSW |
16 |
93,567,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3609:Dop1b
|
UTSW |
16 |
93,536,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3792:Dop1b
|
UTSW |
16 |
93,568,734 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R4364:Dop1b
|
UTSW |
16 |
93,567,812 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4380:Dop1b
|
UTSW |
16 |
93,513,120 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4455:Dop1b
|
UTSW |
16 |
93,563,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4779:Dop1b
|
UTSW |
16 |
93,553,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4820:Dop1b
|
UTSW |
16 |
93,589,978 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4834:Dop1b
|
UTSW |
16 |
93,536,892 (GRCm39) |
start codon destroyed |
probably null |
0.70 |
|
R4866:Dop1b
|
UTSW |
16 |
93,560,318 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4882:Dop1b
|
UTSW |
16 |
93,549,802 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4900:Dop1b
|
UTSW |
16 |
93,560,318 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5153:Dop1b
|
UTSW |
16 |
93,570,891 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5176:Dop1b
|
UTSW |
16 |
93,536,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5206:Dop1b
|
UTSW |
16 |
93,598,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5320:Dop1b
|
UTSW |
16 |
93,536,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5361:Dop1b
|
UTSW |
16 |
93,567,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5380:Dop1b
|
UTSW |
16 |
93,560,298 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5476:Dop1b
|
UTSW |
16 |
93,570,801 (GRCm39) |
splice site |
probably null |
|
|
R5502:Dop1b
|
UTSW |
16 |
93,590,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5543:Dop1b
|
UTSW |
16 |
93,595,808 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5557:Dop1b
|
UTSW |
16 |
93,560,819 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5901:Dop1b
|
UTSW |
16 |
93,566,639 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5907:Dop1b
|
UTSW |
16 |
93,598,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6174:Dop1b
|
UTSW |
16 |
93,563,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6256:Dop1b
|
UTSW |
16 |
93,604,102 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6383:Dop1b
|
UTSW |
16 |
93,579,136 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6525:Dop1b
|
UTSW |
16 |
93,606,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6554:Dop1b
|
UTSW |
16 |
93,557,346 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6823:Dop1b
|
UTSW |
16 |
93,552,373 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7036:Dop1b
|
UTSW |
16 |
93,574,378 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7058:Dop1b
|
UTSW |
16 |
93,573,878 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7061:Dop1b
|
UTSW |
16 |
93,558,951 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7209:Dop1b
|
UTSW |
16 |
93,566,733 (GRCm39) |
missense |
probably benign |
|
|
R7214:Dop1b
|
UTSW |
16 |
93,607,023 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7232:Dop1b
|
UTSW |
16 |
93,557,373 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7255:Dop1b
|
UTSW |
16 |
93,567,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7335:Dop1b
|
UTSW |
16 |
93,544,396 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7535:Dop1b
|
UTSW |
16 |
93,603,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7700:Dop1b
|
UTSW |
16 |
93,595,649 (GRCm39) |
splice site |
probably null |
|
|
R7763:Dop1b
|
UTSW |
16 |
93,552,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7814:Dop1b
|
UTSW |
16 |
93,596,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7839:Dop1b
|
UTSW |
16 |
93,560,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7862:Dop1b
|
UTSW |
16 |
93,546,851 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7894:Dop1b
|
UTSW |
16 |
93,607,092 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7952:Dop1b
|
UTSW |
16 |
93,546,848 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7956:Dop1b
|
UTSW |
16 |
93,567,916 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8033:Dop1b
|
UTSW |
16 |
93,566,371 (GRCm39) |
missense |
probably benign |
|
|
R8061:Dop1b
|
UTSW |
16 |
93,546,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8067:Dop1b
|
UTSW |
16 |
93,562,336 (GRCm39) |
nonsense |
probably null |
|
|
R8146:Dop1b
|
UTSW |
16 |
93,546,827 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8184:Dop1b
|
UTSW |
16 |
93,573,881 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8221:Dop1b
|
UTSW |
16 |
93,546,847 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8263:Dop1b
|
UTSW |
16 |
93,559,083 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8329:Dop1b
|
UTSW |
16 |
93,568,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8555:Dop1b
|
UTSW |
16 |
93,568,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8683:Dop1b
|
UTSW |
16 |
93,570,809 (GRCm39) |
missense |
probably benign |
|
|
R8683:Dop1b
|
UTSW |
16 |
93,568,699 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8716:Dop1b
|
UTSW |
16 |
93,577,673 (GRCm39) |
nonsense |
probably null |
|
|
R8807:Dop1b
|
UTSW |
16 |
93,558,973 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8840:Dop1b
|
UTSW |
16 |
93,607,005 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8851:Dop1b
|
UTSW |
16 |
93,559,398 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8884:Dop1b
|
UTSW |
16 |
93,556,550 (GRCm39) |
missense |
probably benign |
|
|
R8976:Dop1b
|
UTSW |
16 |
93,558,969 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9219:Dop1b
|
UTSW |
16 |
93,567,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9238:Dop1b
|
UTSW |
16 |
93,546,018 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9284:Dop1b
|
UTSW |
16 |
93,557,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9289:Dop1b
|
UTSW |
16 |
93,568,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9298:Dop1b
|
UTSW |
16 |
93,597,087 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9338:Dop1b
|
UTSW |
16 |
93,600,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9346:Dop1b
|
UTSW |
16 |
93,577,702 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9444:Dop1b
|
UTSW |
16 |
93,607,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9500:Dop1b
|
UTSW |
16 |
93,607,171 (GRCm39) |
missense |
probably benign |
|
|
R9601:Dop1b
|
UTSW |
16 |
93,544,531 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9793:Dop1b
|
UTSW |
16 |
93,598,503 (GRCm39) |
missense |
probably benign |
0.30 |
|
Z1088:Dop1b
|
UTSW |
16 |
93,560,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Dop1b
|
UTSW |
16 |
93,604,756 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
Z1176:Dop1b
|
UTSW |
16 |
93,600,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dop1b
|
UTSW |
16 |
93,566,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dop1b
|
UTSW |
16 |
93,560,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCCGTGCTTAAGACCAATCCCAAG -3'
(R):5'- ATGAGGCTCTCCTCAAAGAGGCTG -3'
Sequencing Primer
(F):5'- TCCCAAGGAGTTCATTGAGGC -3'
(R):5'- CTCAAAGAGGCTGTCCTCC -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation