Incidental Mutation 'R5964:Slit3'
| ID |
471965 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Slit3
|
| Ensembl Gene |
ENSMUSG00000056427 |
| Gene Name |
slit guidance ligand 3 |
| Synonyms |
Slit1, b2b2362.1Clo |
| MMRRC Submission |
044149-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.871)
|
| Stock # |
R5964 (G1)
|
| Quality Score |
170 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
35012283-35599334 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 35591063 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Cysteine
at position 1292
(R1292C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066857
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000069837]
|
| AlphaFold |
Q9WVB4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000069837
AA Change: R1292C
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000066857
Gene: ENSMUSG00000056427
AA Change: R1292C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
23 |
N/A |
INTRINSIC |
|
LRRNT
|
33 |
65 |
2.12e-8 |
SMART |
|
LRR
|
59 |
83 |
1.37e2 |
SMART |
|
LRR_TYP
|
84 |
107 |
1.12e-3 |
SMART |
|
LRR_TYP
|
108 |
131 |
7.78e-3 |
SMART |
|
LRR_TYP
|
132 |
155 |
5.42e-2 |
SMART |
|
LRR
|
156 |
179 |
5.88e0 |
SMART |
|
LRR
|
180 |
203 |
7.55e-1 |
SMART |
|
LRRCT
|
215 |
264 |
1.33e-6 |
SMART |
|
LRRNT
|
279 |
311 |
6.79e-7 |
SMART |
|
LRR
|
305 |
329 |
1.16e2 |
SMART |
|
LRR
|
330 |
353 |
1.26e1 |
SMART |
|
LRR_TYP
|
354 |
377 |
2.79e-4 |
SMART |
|
LRR
|
378 |
401 |
4.05e-1 |
SMART |
|
LRR
|
402 |
425 |
4.05e-1 |
SMART |
|
LRRCT
|
437 |
486 |
7.75e-8 |
SMART |
|
LRRNT
|
504 |
536 |
1.95e-7 |
SMART |
|
LRR_TYP
|
556 |
579 |
7.49e-5 |
SMART |
|
LRR
|
581 |
603 |
6.41e1 |
SMART |
|
LRR_TYP
|
604 |
627 |
2.53e-2 |
SMART |
|
LRR
|
628 |
651 |
1.76e-1 |
SMART |
|
LRRCT
|
663 |
712 |
2.52e-7 |
SMART |
|
LRRNT
|
724 |
756 |
3e-8 |
SMART |
|
LRR
|
774 |
797 |
2.14e0 |
SMART |
|
LRR_TYP
|
798 |
821 |
2.95e-3 |
SMART |
|
LRR_TYP
|
822 |
845 |
2.43e-4 |
SMART |
|
LRRCT
|
857 |
906 |
1.12e-13 |
SMART |
|
EGF
|
919 |
953 |
6.86e-4 |
SMART |
|
EGF
|
958 |
994 |
8.84e-7 |
SMART |
|
EGF
|
999 |
1032 |
1.13e-4 |
SMART |
|
EGF
|
1037 |
1072 |
2.3e-5 |
SMART |
|
EGF_CA
|
1074 |
1110 |
5.92e-8 |
SMART |
|
EGF
|
1122 |
1155 |
3.79e-6 |
SMART |
|
LamG
|
1178 |
1314 |
3.16e-34 |
SMART |
|
EGF
|
1331 |
1365 |
2.19e-2 |
SMART |
|
EGF
|
1371 |
1403 |
1.13e-4 |
SMART |
|
EGF
|
1411 |
1444 |
5.57e-4 |
SMART |
|
CT
|
1455 |
1523 |
4.56e-5 |
SMART |
|
| Meta Mutation Damage Score |
0.5689 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.5%
- 10x: 97.5%
- 20x: 92.2%
|
| Validation Efficiency |
96% (87/91) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
PHENOTYPE: Mice homozygous for a gene trap allele show congenital diaphragmatic hernia (CDH), variable renal defects and enlarged heart right ventricles. Mice homozygous for either of two reporter alleles show diaphragm dysgenesis and die prematurely; those with end-stage CDH show dyspnea and lung congestion. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam15 |
G |
A |
3: 89,250,874 (GRCm39) |
Q581* |
probably null |
Het |
| Agl |
A |
G |
3: 116,587,423 (GRCm39) |
V44A |
probably damaging |
Het |
| Alpk3 |
T |
A |
7: 80,742,008 (GRCm39) |
D608E |
possibly damaging |
Het |
| Aspm |
C |
A |
1: 139,382,965 (GRCm39) |
|
probably benign |
Het |
| Bbs2 |
T |
C |
8: 94,794,995 (GRCm39) |
N692S |
probably benign |
Het |
| Bend4 |
A |
G |
5: 67,575,161 (GRCm39) |
I240T |
probably benign |
Het |
| Casp8 |
G |
T |
1: 58,872,895 (GRCm39) |
R277L |
possibly damaging |
Het |
| Ccdc61 |
A |
T |
7: 18,634,865 (GRCm39) |
I123N |
probably damaging |
Het |
| Ccr9 |
T |
G |
9: 123,608,499 (GRCm39) |
I60M |
probably benign |
Het |
| Cd163 |
T |
A |
6: 124,303,531 (GRCm39) |
W1066R |
probably benign |
Het |
| Cd226 |
A |
T |
18: 89,225,307 (GRCm39) |
H68L |
probably benign |
Het |
| Cdkn3 |
T |
A |
14: 47,004,674 (GRCm39) |
C79S |
probably null |
Het |
| Cnnm1 |
A |
T |
19: 43,458,162 (GRCm39) |
E658V |
probably benign |
Het |
| Cog7 |
T |
C |
7: 121,555,252 (GRCm39) |
R304G |
probably damaging |
Het |
| Cpt1a |
T |
A |
19: 3,415,760 (GRCm39) |
V286E |
possibly damaging |
Het |
| Creg2 |
C |
A |
1: 39,664,122 (GRCm39) |
R212L |
probably benign |
Het |
| Cyp26a1 |
T |
G |
19: 37,688,410 (GRCm39) |
S311A |
probably damaging |
Het |
| Cyp2b10 |
T |
C |
7: 25,625,648 (GRCm39) |
Y484H |
probably benign |
Het |
| Cyp3a44 |
T |
A |
5: 145,725,277 (GRCm39) |
Y308F |
possibly damaging |
Het |
| Dlg5 |
A |
G |
14: 24,214,157 (GRCm39) |
V744A |
probably benign |
Het |
| Dlgap2 |
T |
A |
8: 14,777,128 (GRCm39) |
Y124* |
probably null |
Het |
| Dnah3 |
T |
C |
7: 119,522,103 (GRCm39) |
D4030G |
probably benign |
Het |
| Dnah5 |
A |
G |
15: 28,458,730 (GRCm39) |
T4456A |
possibly damaging |
Het |
| Dtx2 |
T |
A |
5: 136,052,553 (GRCm39) |
V347D |
probably benign |
Het |
| Gigyf2 |
C |
T |
1: 87,334,889 (GRCm39) |
T294M |
probably damaging |
Het |
| Gli3 |
C |
G |
13: 15,900,747 (GRCm39) |
S1378* |
probably null |
Het |
| Gnao1 |
G |
A |
8: 94,693,627 (GRCm39) |
D337N |
probably benign |
Het |
| Gp2 |
T |
A |
7: 119,048,352 (GRCm39) |
Q422L |
probably benign |
Het |
| Ifit1 |
T |
A |
19: 34,625,869 (GRCm39) |
M335K |
possibly damaging |
Het |
| Ism1 |
T |
C |
2: 139,520,677 (GRCm39) |
S30P |
probably benign |
Het |
| Itgax |
A |
G |
7: 127,739,619 (GRCm39) |
D677G |
probably damaging |
Het |
| Kansl1l |
G |
A |
1: 66,765,081 (GRCm39) |
A442V |
probably damaging |
Het |
| Kif13a |
T |
C |
13: 46,925,000 (GRCm39) |
I311M |
probably damaging |
Het |
| Lrrc37 |
A |
G |
11: 103,432,946 (GRCm39) |
S1232P |
possibly damaging |
Het |
| Lsm14b |
T |
A |
2: 179,673,218 (GRCm39) |
S84R |
probably benign |
Het |
| Lzts3 |
A |
G |
2: 130,478,208 (GRCm39) |
Y297H |
probably damaging |
Het |
| Map4k3 |
A |
G |
17: 80,952,191 (GRCm39) |
I205T |
probably damaging |
Het |
| Matn2 |
A |
T |
15: 34,410,311 (GRCm39) |
N501I |
probably damaging |
Het |
| Mctp2 |
T |
C |
7: 71,752,925 (GRCm39) |
E776G |
probably damaging |
Het |
| Mex3d |
A |
T |
10: 80,218,421 (GRCm39) |
N265K |
probably damaging |
Het |
| Myo5a |
A |
G |
9: 75,111,115 (GRCm39) |
T1534A |
probably benign |
Het |
| Ncoa7 |
T |
C |
10: 30,580,632 (GRCm39) |
M35V |
probably damaging |
Het |
| Nek4 |
G |
A |
14: 30,679,036 (GRCm39) |
|
probably null |
Het |
| Ngrn |
T |
C |
7: 79,911,681 (GRCm39) |
|
probably null |
Het |
| Nlrp1a |
T |
A |
11: 71,013,846 (GRCm39) |
Q468L |
probably benign |
Het |
| Or11g27 |
T |
A |
14: 50,771,655 (GRCm39) |
M262K |
probably damaging |
Het |
| Or5b98 |
A |
C |
19: 12,931,895 (GRCm39) |
Q314P |
probably benign |
Het |
| Phtf2 |
T |
C |
5: 20,980,932 (GRCm39) |
D433G |
probably damaging |
Het |
| Prdm13 |
G |
A |
4: 21,683,852 (GRCm39) |
Q140* |
probably null |
Het |
| Prtg |
G |
A |
9: 72,799,536 (GRCm39) |
G778E |
probably benign |
Het |
| Pum3 |
T |
C |
19: 27,397,451 (GRCm39) |
E308G |
probably damaging |
Het |
| Pwp1 |
T |
G |
10: 85,718,750 (GRCm39) |
F306V |
probably damaging |
Het |
| Rab24 |
A |
T |
13: 55,469,389 (GRCm39) |
Y27N |
probably damaging |
Het |
| Rnf215 |
T |
C |
11: 4,085,898 (GRCm39) |
F126L |
probably benign |
Het |
| Samd13 |
A |
T |
3: 146,386,451 (GRCm39) |
|
probably benign |
Het |
| Serac1 |
T |
A |
17: 6,115,324 (GRCm39) |
H213L |
probably benign |
Het |
| Slc45a3 |
A |
G |
1: 131,905,811 (GRCm39) |
E278G |
probably damaging |
Het |
| Slx4 |
A |
T |
16: 3,818,815 (GRCm39) |
|
probably null |
Het |
| Smarca4 |
C |
A |
9: 21,558,726 (GRCm39) |
T631K |
probably benign |
Het |
| Snx16 |
C |
T |
3: 10,499,541 (GRCm39) |
R163Q |
possibly damaging |
Het |
| Stk40 |
T |
C |
4: 126,022,688 (GRCm39) |
V140A |
probably damaging |
Het |
| Tcf12 |
A |
T |
9: 71,775,522 (GRCm39) |
D409E |
probably damaging |
Het |
| Tgfbr2 |
G |
T |
9: 115,939,323 (GRCm39) |
T168K |
possibly damaging |
Het |
| Ticam1 |
G |
T |
17: 56,578,703 (GRCm39) |
H131N |
probably damaging |
Het |
| Ttn |
C |
A |
2: 76,543,855 (GRCm39) |
E31298* |
probably null |
Het |
| Ttn |
C |
A |
2: 76,660,232 (GRCm39) |
R7458I |
possibly damaging |
Het |
| Usp7 |
A |
G |
16: 8,529,966 (GRCm39) |
V133A |
possibly damaging |
Het |
| Wbp1l |
C |
T |
19: 46,642,619 (GRCm39) |
R191* |
probably null |
Het |
| Wdfy4 |
T |
C |
14: 32,827,968 (GRCm39) |
E1118G |
probably damaging |
Het |
| Zfp81 |
G |
C |
17: 33,555,819 (GRCm39) |
P3A |
probably damaging |
Het |
| Znhit6 |
A |
G |
3: 145,282,688 (GRCm39) |
K21R |
possibly damaging |
Het |
|
| Other mutations in Slit3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00731:Slit3
|
APN |
11 |
35,512,981 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01324:Slit3
|
APN |
11 |
35,501,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01612:Slit3
|
APN |
11 |
35,591,211 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02145:Slit3
|
APN |
11 |
35,520,569 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02146:Slit3
|
APN |
11 |
35,125,675 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02430:Slit3
|
APN |
11 |
35,068,601 (GRCm39) |
splice site |
probably null |
|
|
IGL02528:Slit3
|
APN |
11 |
35,469,801 (GRCm39) |
missense |
probably benign |
|
|
IGL02530:Slit3
|
APN |
11 |
35,598,969 (GRCm39) |
makesense |
probably null |
|
|
IGL02640:Slit3
|
APN |
11 |
35,591,172 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02819:Slit3
|
APN |
11 |
35,062,417 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02839:Slit3
|
APN |
11 |
35,539,874 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL03150:Slit3
|
APN |
11 |
35,399,084 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL03161:Slit3
|
APN |
11 |
35,591,241 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03336:Slit3
|
APN |
11 |
35,560,928 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Bloated
|
UTSW |
11 |
35,524,779 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
Quellung
|
UTSW |
11 |
35,542,647 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02988:Slit3
|
UTSW |
11 |
35,598,890 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4791001:Slit3
|
UTSW |
11 |
35,552,072 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0013:Slit3
|
UTSW |
11 |
35,598,745 (GRCm39) |
missense |
probably benign |
|
|
R0013:Slit3
|
UTSW |
11 |
35,598,745 (GRCm39) |
missense |
probably benign |
|
|
R0334:Slit3
|
UTSW |
11 |
35,469,928 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0385:Slit3
|
UTSW |
11 |
35,591,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0840:Slit3
|
UTSW |
11 |
35,514,263 (GRCm39) |
splice site |
probably benign |
|
|
R1065:Slit3
|
UTSW |
11 |
35,012,462 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1364:Slit3
|
UTSW |
11 |
35,560,934 (GRCm39) |
missense |
probably benign |
|
|
R1476:Slit3
|
UTSW |
11 |
35,577,126 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1508:Slit3
|
UTSW |
11 |
35,461,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1665:Slit3
|
UTSW |
11 |
35,125,733 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1692:Slit3
|
UTSW |
11 |
35,550,171 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1696:Slit3
|
UTSW |
11 |
35,566,750 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1727:Slit3
|
UTSW |
11 |
35,520,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1752:Slit3
|
UTSW |
11 |
35,455,480 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1970:Slit3
|
UTSW |
11 |
35,521,668 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2077:Slit3
|
UTSW |
11 |
35,435,575 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2126:Slit3
|
UTSW |
11 |
35,579,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Slit3
|
UTSW |
11 |
35,503,088 (GRCm39) |
splice site |
probably null |
|
|
R2162:Slit3
|
UTSW |
11 |
35,579,509 (GRCm39) |
missense |
probably null |
1.00 |
|
R2873:Slit3
|
UTSW |
11 |
35,435,620 (GRCm39) |
nonsense |
probably null |
|
|
R3813:Slit3
|
UTSW |
11 |
35,566,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3831:Slit3
|
UTSW |
11 |
35,579,509 (GRCm39) |
missense |
probably null |
1.00 |
|
R3832:Slit3
|
UTSW |
11 |
35,579,509 (GRCm39) |
missense |
probably null |
1.00 |
|
R3833:Slit3
|
UTSW |
11 |
35,579,509 (GRCm39) |
missense |
probably null |
1.00 |
|
R3839:Slit3
|
UTSW |
11 |
35,399,064 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4152:Slit3
|
UTSW |
11 |
35,589,147 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4387:Slit3
|
UTSW |
11 |
35,574,875 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4795:Slit3
|
UTSW |
11 |
35,542,647 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4910:Slit3
|
UTSW |
11 |
35,523,549 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4933:Slit3
|
UTSW |
11 |
35,579,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5048:Slit3
|
UTSW |
11 |
35,479,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5106:Slit3
|
UTSW |
11 |
35,503,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5138:Slit3
|
UTSW |
11 |
35,479,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5218:Slit3
|
UTSW |
11 |
35,575,002 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5338:Slit3
|
UTSW |
11 |
35,512,975 (GRCm39) |
missense |
probably benign |
|
|
R5354:Slit3
|
UTSW |
11 |
35,566,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5436:Slit3
|
UTSW |
11 |
35,598,738 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5896:Slit3
|
UTSW |
11 |
35,598,932 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5933:Slit3
|
UTSW |
11 |
35,520,578 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5963:Slit3
|
UTSW |
11 |
35,591,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6125:Slit3
|
UTSW |
11 |
35,461,560 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6153:Slit3
|
UTSW |
11 |
35,591,310 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6484:Slit3
|
UTSW |
11 |
35,552,125 (GRCm39) |
missense |
probably benign |
|
|
R6526:Slit3
|
UTSW |
11 |
35,552,119 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6797:Slit3
|
UTSW |
11 |
35,524,779 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R6887:Slit3
|
UTSW |
11 |
35,435,633 (GRCm39) |
splice site |
probably null |
|
|
R7067:Slit3
|
UTSW |
11 |
35,399,057 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7150:Slit3
|
UTSW |
11 |
35,461,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7228:Slit3
|
UTSW |
11 |
35,490,245 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7232:Slit3
|
UTSW |
11 |
35,501,516 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7418:Slit3
|
UTSW |
11 |
35,577,255 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R7545:Slit3
|
UTSW |
11 |
35,591,139 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7727:Slit3
|
UTSW |
11 |
35,574,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7820:Slit3
|
UTSW |
11 |
35,591,235 (GRCm39) |
missense |
probably benign |
0.23 |
|
R8177:Slit3
|
UTSW |
11 |
35,469,919 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8179:Slit3
|
UTSW |
11 |
35,554,903 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8416:Slit3
|
UTSW |
11 |
35,399,062 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8417:Slit3
|
UTSW |
11 |
35,501,438 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8476:Slit3
|
UTSW |
11 |
35,520,596 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8785:Slit3
|
UTSW |
11 |
35,560,968 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8955:Slit3
|
UTSW |
11 |
35,589,207 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9040:Slit3
|
UTSW |
11 |
35,594,136 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9068:Slit3
|
UTSW |
11 |
35,574,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9088:Slit3
|
UTSW |
11 |
35,012,463 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9266:Slit3
|
UTSW |
11 |
35,598,808 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9539:Slit3
|
UTSW |
11 |
35,589,155 (GRCm39) |
nonsense |
probably null |
|
|
R9636:Slit3
|
UTSW |
11 |
35,594,088 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0028:Slit3
|
UTSW |
11 |
35,455,464 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Slit3
|
UTSW |
11 |
35,598,751 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGGATAAGGCCAGGGCTTTG -3'
(R):5'- CCGAGCTTCCTGATCACATAGC -3'
Sequencing Primer
(F):5'- TTGGCCTGCTAACCCTGAG -3'
(R):5'- TTCCTGATCACATAGCGGACCG -3'
|
| Posted On |
2017-03-31 |
Incidental Mutation