Incidental Mutation 'R4899:Rnf123'
| ID |
472512 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rnf123
|
| Ensembl Gene |
ENSMUSG00000041528 |
| Gene Name |
ring finger protein 123 |
| Synonyms |
KPC1 |
| MMRRC Submission |
042503-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.163)
|
| Stock # |
R4899 (G1)
|
| Quality Score |
205 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
107928869-107957183 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 107940879 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Histidine
at position 654
(R654H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125495
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047746]
[ENSMUST00000160249]
[ENSMUST00000160649]
[ENSMUST00000178267]
[ENSMUST00000162355]
[ENSMUST00000162753]
|
| AlphaFold |
Q5XPI3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000047746
AA Change: R660H
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000040803
Gene: ENSMUSG00000041528
AA Change: R660H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1047 |
1067 |
N/A |
INTRINSIC |
|
low complexity region
|
1242 |
1251 |
N/A |
INTRINSIC |
|
RING
|
1260 |
1297 |
5.27e-4 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159136
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159306
|
| SMART Domains |
Protein: ENSMUSP00000125695
Gene: ENSMUSG00000041528
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
172 |
192 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000160249
AA Change: R654H
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000124548
Gene: ENSMUSG00000041528
AA Change: R654H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1245 |
N/A |
INTRINSIC |
|
RING
|
1254 |
1291 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000160649
AA Change: R654H
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000125495
Gene: ENSMUSG00000041528
AA Change: R654H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000160841
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000161673
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000178267
AA Change: R654H
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000136953
Gene: ENSMUSG00000041528
AA Change: R654H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1041 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1236 |
1245 |
N/A |
INTRINSIC |
|
RING
|
1254 |
1291 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000162355
AA Change: R660H
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000125745
Gene: ENSMUSG00000041528
AA Change: R660H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
104 |
115 |
N/A |
INTRINSIC |
|
SPRY
|
132 |
253 |
1.52e-28 |
SMART |
|
low complexity region
|
471 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
coiled coil region
|
1047 |
1067 |
N/A |
INTRINSIC |
|
low complexity region
|
1242 |
1251 |
N/A |
INTRINSIC |
|
RING
|
1260 |
1297 |
5.27e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162753
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abhd18 |
C |
G |
3: 40,860,304 (GRCm39) |
|
probably null |
Het |
| Adra2c |
A |
T |
5: 35,437,705 (GRCm39) |
Y159F |
probably damaging |
Het |
| Alkal2 |
T |
A |
12: 30,934,972 (GRCm39) |
S64T |
probably benign |
Het |
| Apbb1ip |
T |
C |
2: 22,713,361 (GRCm39) |
V72A |
unknown |
Het |
| Atp13a5 |
A |
G |
16: 29,197,318 (GRCm39) |
L13P |
probably damaging |
Het |
| Azin2 |
G |
A |
4: 128,828,446 (GRCm39) |
P254S |
probably benign |
Het |
| Bmpr1b |
T |
C |
3: 141,546,444 (GRCm39) |
R481G |
probably damaging |
Het |
| Cacna2d4 |
G |
A |
6: 119,245,157 (GRCm39) |
W288* |
probably null |
Het |
| Cass4 |
A |
G |
2: 172,269,789 (GRCm39) |
T626A |
probably benign |
Het |
| Cep112 |
T |
A |
11: 108,497,110 (GRCm39) |
D683E |
probably damaging |
Het |
| Cfap300 |
A |
T |
9: 8,022,494 (GRCm39) |
S243T |
possibly damaging |
Het |
| Chat |
G |
T |
14: 32,170,934 (GRCm39) |
S188R |
possibly damaging |
Het |
| Cit |
A |
G |
5: 116,001,087 (GRCm39) |
Y162C |
possibly damaging |
Het |
| Clca3a1 |
T |
A |
3: 144,443,722 (GRCm39) |
Y676F |
probably damaging |
Het |
| Clec2h |
A |
G |
6: 128,652,787 (GRCm39) |
N185D |
probably benign |
Het |
| Cnbd2 |
G |
T |
2: 156,181,141 (GRCm39) |
V192F |
probably benign |
Het |
| Col6a3 |
C |
A |
1: 90,730,149 (GRCm39) |
G1112V |
probably damaging |
Het |
| Csta2 |
A |
T |
16: 36,077,731 (GRCm39) |
Y96F |
possibly damaging |
Het |
| Cyp3a25 |
A |
G |
5: 145,914,481 (GRCm39) |
F483S |
possibly damaging |
Het |
| Dscam |
T |
C |
16: 96,485,018 (GRCm39) |
E1103G |
probably benign |
Het |
| Dync2h1 |
G |
A |
9: 7,131,921 (GRCm39) |
Q1629* |
probably null |
Het |
| Enpp6 |
A |
G |
8: 47,440,118 (GRCm39) |
Y38C |
probably damaging |
Het |
| Epg5 |
T |
A |
18: 78,028,272 (GRCm39) |
L1271Q |
probably damaging |
Het |
| Fam47e |
G |
A |
5: 92,722,528 (GRCm39) |
V75I |
probably benign |
Het |
| Fat3 |
T |
C |
9: 15,881,095 (GRCm39) |
D3259G |
probably damaging |
Het |
| Fbxw28 |
T |
C |
9: 109,159,921 (GRCm39) |
D211G |
probably damaging |
Het |
| Flnc |
A |
G |
6: 29,446,842 (GRCm39) |
N990D |
probably benign |
Het |
| Frat1 |
T |
G |
19: 41,818,761 (GRCm39) |
L52R |
probably damaging |
Het |
| Ftmt |
C |
G |
18: 52,464,658 (GRCm39) |
|
probably benign |
Het |
| H2-M1 |
C |
T |
17: 36,982,112 (GRCm39) |
G163D |
probably benign |
Het |
| Hapln1 |
A |
G |
13: 89,749,769 (GRCm39) |
K105E |
possibly damaging |
Het |
| Igkv17-127 |
G |
T |
6: 67,838,381 (GRCm39) |
A31S |
probably benign |
Het |
| Il6st |
T |
C |
13: 112,637,695 (GRCm39) |
L628P |
probably damaging |
Het |
| Kcnj6 |
A |
G |
16: 94,633,472 (GRCm39) |
I213T |
probably damaging |
Het |
| Kidins220 |
T |
C |
12: 25,063,442 (GRCm39) |
|
probably null |
Het |
| Lama2 |
TTTGCGCATT |
TTT |
10: 26,919,639 (GRCm39) |
|
probably null |
Het |
| Llgl1 |
C |
T |
11: 60,600,394 (GRCm39) |
P581L |
probably benign |
Het |
| Mertk |
C |
A |
2: 128,625,845 (GRCm39) |
P660Q |
probably damaging |
Het |
| Mrtfa |
A |
G |
15: 80,902,587 (GRCm39) |
Y241H |
probably damaging |
Het |
| Mtarc2 |
A |
T |
1: 184,577,821 (GRCm39) |
I65N |
probably damaging |
Het |
| Napepld |
A |
G |
5: 21,888,438 (GRCm39) |
Y4H |
probably benign |
Het |
| Ncam1 |
T |
A |
9: 49,456,551 (GRCm39) |
|
probably null |
Het |
| Nuak2 |
A |
T |
1: 132,252,724 (GRCm39) |
K93* |
probably null |
Het |
| Oat |
A |
T |
7: 132,165,951 (GRCm39) |
D211E |
probably benign |
Het |
| Or1j19 |
A |
G |
2: 36,676,810 (GRCm39) |
Q91R |
probably benign |
Het |
| Or2aj6 |
G |
A |
16: 19,442,950 (GRCm39) |
A300V |
probably benign |
Het |
| Or4c109 |
A |
C |
2: 88,818,454 (GRCm39) |
L31V |
probably null |
Het |
| Or51b17 |
A |
G |
7: 103,542,672 (GRCm39) |
I90T |
possibly damaging |
Het |
| Or7a39 |
A |
T |
10: 78,715,041 (GRCm39) |
S12C |
probably benign |
Het |
| Pde4dip |
C |
A |
3: 97,616,874 (GRCm39) |
K1789N |
probably damaging |
Het |
| Piezo2 |
T |
C |
18: 63,211,862 (GRCm39) |
I1322V |
possibly damaging |
Het |
| Pih1d1 |
A |
G |
7: 44,803,951 (GRCm39) |
|
probably benign |
Het |
| Plekhd1 |
T |
C |
12: 80,769,101 (GRCm39) |
S454P |
probably damaging |
Het |
| Polr2h |
G |
A |
16: 20,539,303 (GRCm39) |
V89M |
probably damaging |
Het |
| Pptc7 |
G |
A |
5: 122,422,780 (GRCm39) |
G17S |
possibly damaging |
Het |
| Pramel55 |
T |
C |
5: 95,949,586 (GRCm39) |
V111A |
probably benign |
Het |
| Ptpra |
T |
C |
2: 130,386,356 (GRCm39) |
V602A |
probably damaging |
Het |
| Rufy4 |
T |
C |
1: 74,186,822 (GRCm39) |
C537R |
probably damaging |
Het |
| Samsn1 |
A |
G |
16: 75,675,991 (GRCm39) |
S135P |
probably damaging |
Het |
| Sgsm3 |
A |
G |
15: 80,890,980 (GRCm39) |
N147S |
probably benign |
Het |
| Shoc1 |
T |
C |
4: 59,062,640 (GRCm39) |
Y872C |
probably damaging |
Het |
| Slc22a29 |
T |
C |
19: 8,138,933 (GRCm39) |
T510A |
probably benign |
Het |
| Smc4 |
T |
A |
3: 68,939,144 (GRCm39) |
H978Q |
probably damaging |
Het |
| Sox7 |
G |
A |
14: 64,185,927 (GRCm39) |
R321H |
probably damaging |
Het |
| Spred3 |
T |
C |
7: 28,861,258 (GRCm39) |
D307G |
probably damaging |
Het |
| Syne2 |
T |
A |
12: 75,900,875 (GRCm39) |
D11E |
probably benign |
Het |
| Tob1 |
ACAGCAGCAGCAGCAGCAGCAGCAGCA |
ACAGCAGCAGCAGCAGCAGCAGCA |
11: 94,105,278 (GRCm39) |
|
probably benign |
Het |
| Top2b |
A |
T |
14: 16,387,313 (GRCm38) |
I134F |
probably damaging |
Het |
| Tspan1 |
T |
A |
4: 116,020,563 (GRCm39) |
R206* |
probably null |
Het |
| Ttc3 |
A |
T |
16: 94,230,314 (GRCm39) |
N837I |
probably damaging |
Het |
| Vmn1r36 |
T |
C |
6: 66,693,549 (GRCm39) |
T72A |
possibly damaging |
Het |
| Vmn2r10 |
A |
G |
5: 109,151,324 (GRCm39) |
S97P |
probably damaging |
Het |
| Zfp2 |
T |
A |
11: 50,790,841 (GRCm39) |
I401F |
probably damaging |
Het |
| Zfp629 |
T |
C |
7: 127,210,190 (GRCm39) |
T540A |
possibly damaging |
Het |
| Zfr |
G |
A |
15: 12,166,231 (GRCm39) |
V834I |
probably benign |
Het |
|
| Other mutations in Rnf123 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00950:Rnf123
|
APN |
9 |
107,944,594 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01358:Rnf123
|
APN |
9 |
107,946,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01464:Rnf123
|
APN |
9 |
107,929,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01637:Rnf123
|
APN |
9 |
107,935,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01669:Rnf123
|
APN |
9 |
107,935,555 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01905:Rnf123
|
APN |
9 |
107,948,569 (GRCm39) |
splice site |
probably benign |
|
|
IGL02070:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02072:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02073:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02074:Rnf123
|
APN |
9 |
107,944,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02079:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02080:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02231:Rnf123
|
APN |
9 |
107,943,598 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02281:Rnf123
|
APN |
9 |
107,948,651 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02336:Rnf123
|
APN |
9 |
107,939,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02543:Rnf123
|
APN |
9 |
107,943,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02565:Rnf123
|
APN |
9 |
107,929,411 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02571:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02572:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02574:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02586:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02589:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02600:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02601:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02602:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02603:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02609:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02628:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02629:Rnf123
|
APN |
9 |
107,947,988 (GRCm39) |
splice site |
probably benign |
|
|
IGL02629:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02630:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02631:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02632:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02650:Rnf123
|
APN |
9 |
107,946,947 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL02690:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02691:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02692:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02693:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02713:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02736:Rnf123
|
APN |
9 |
107,945,501 (GRCm39) |
nonsense |
probably null |
|
|
IGL02929:Rnf123
|
APN |
9 |
107,946,275 (GRCm39) |
missense |
probably benign |
|
|
R1175:Rnf123
|
UTSW |
9 |
107,954,572 (GRCm39) |
missense |
probably benign |
|
|
R1465:Rnf123
|
UTSW |
9 |
107,948,665 (GRCm39) |
splice site |
probably benign |
|
|
R1502:Rnf123
|
UTSW |
9 |
107,945,709 (GRCm39) |
splice site |
probably null |
|
|
R1682:Rnf123
|
UTSW |
9 |
107,954,597 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1817:Rnf123
|
UTSW |
9 |
107,940,125 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1855:Rnf123
|
UTSW |
9 |
107,938,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2394:Rnf123
|
UTSW |
9 |
107,940,735 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2483:Rnf123
|
UTSW |
9 |
107,940,720 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3896:Rnf123
|
UTSW |
9 |
107,946,302 (GRCm39) |
splice site |
probably benign |
|
|
R3940:Rnf123
|
UTSW |
9 |
107,941,234 (GRCm39) |
splice site |
probably benign |
|
|
R4206:Rnf123
|
UTSW |
9 |
107,941,162 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4641:Rnf123
|
UTSW |
9 |
107,935,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4714:Rnf123
|
UTSW |
9 |
107,929,638 (GRCm39) |
splice site |
probably null |
|
|
R4767:Rnf123
|
UTSW |
9 |
107,929,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4849:Rnf123
|
UTSW |
9 |
107,933,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5274:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5275:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5276:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5294:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5295:Rnf123
|
UTSW |
9 |
107,941,202 (GRCm39) |
frame shift |
probably null |
|
|
R5394:Rnf123
|
UTSW |
9 |
107,947,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5717:Rnf123
|
UTSW |
9 |
107,944,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6186:Rnf123
|
UTSW |
9 |
107,947,157 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R6449:Rnf123
|
UTSW |
9 |
107,933,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6502:Rnf123
|
UTSW |
9 |
107,945,531 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6944:Rnf123
|
UTSW |
9 |
107,940,822 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7003:Rnf123
|
UTSW |
9 |
107,940,882 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7088:Rnf123
|
UTSW |
9 |
107,935,735 (GRCm39) |
missense |
probably null |
1.00 |
|
R7092:Rnf123
|
UTSW |
9 |
107,945,799 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7100:Rnf123
|
UTSW |
9 |
107,933,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7257:Rnf123
|
UTSW |
9 |
107,946,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7453:Rnf123
|
UTSW |
9 |
107,947,607 (GRCm39) |
splice site |
probably null |
|
|
R7468:Rnf123
|
UTSW |
9 |
107,946,208 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7517:Rnf123
|
UTSW |
9 |
107,947,473 (GRCm39) |
nonsense |
probably null |
|
|
R7577:Rnf123
|
UTSW |
9 |
107,947,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8296:Rnf123
|
UTSW |
9 |
107,940,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8322:Rnf123
|
UTSW |
9 |
107,945,706 (GRCm39) |
missense |
probably benign |
0.26 |
|
R8754:Rnf123
|
UTSW |
9 |
107,948,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8783:Rnf123
|
UTSW |
9 |
107,946,272 (GRCm39) |
missense |
probably benign |
|
|
R9052:Rnf123
|
UTSW |
9 |
107,936,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9156:Rnf123
|
UTSW |
9 |
107,940,227 (GRCm39) |
splice site |
probably benign |
|
|
R9170:Rnf123
|
UTSW |
9 |
107,948,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Rnf123
|
UTSW |
9 |
107,944,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9385:Rnf123
|
UTSW |
9 |
107,929,467 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9394:Rnf123
|
UTSW |
9 |
107,942,905 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9432:Rnf123
|
UTSW |
9 |
107,937,008 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9717:Rnf123
|
UTSW |
9 |
107,954,963 (GRCm39) |
missense |
probably benign |
0.43 |
|
Z1176:Rnf123
|
UTSW |
9 |
107,940,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Rnf123
|
UTSW |
9 |
107,935,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATTCAGTGAGCGAACTTTGAC -3'
(R):5'- GACAGGTAGAGGCTGCTTCATG -3'
Sequencing Primer
(F):5'- GACTTTCTCCATGGTGCTCAGAAG -3'
(R):5'- CTGTAGGCAGGGGTATGACC -3'
|
| Posted On |
2017-04-14 |
Incidental Mutation