Incidental Mutation 'R0505:Nwd2'
| ID |
47461 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nwd2
|
| Ensembl Gene |
ENSMUSG00000090061 |
| Gene Name |
NACHT and WD repeat domain containing 2 |
| Synonyms |
3110047P20Rik, B830017A01Rik |
| MMRRC Submission |
038700-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.119)
|
| Stock # |
R0505 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
63806446-63967889 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 63962454 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 679
(D679E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124712
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000159584]
[ENSMUST00000162166]
|
| AlphaFold |
Q6P5U7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000159584
AA Change: D679E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000124712
Gene: ENSMUSG00000090061
AA Change: D679E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4062
|
42 |
145 |
1.5e-8 |
PFAM |
|
Blast:AAA
|
408 |
691 |
3e-29 |
BLAST |
|
WD40
|
939 |
995 |
1.06e2 |
SMART |
|
WD40
|
998 |
1037 |
8.96e-2 |
SMART |
|
Blast:WD40
|
1091 |
1126 |
9e-19 |
BLAST |
|
Blast:WD40
|
1129 |
1170 |
1e-17 |
BLAST |
|
Blast:WD40
|
1220 |
1260 |
3e-16 |
BLAST |
|
WD40
|
1263 |
1302 |
3.4e-2 |
SMART |
|
WD40
|
1347 |
1385 |
2.65e1 |
SMART |
|
WD40
|
1386 |
1425 |
1.58e2 |
SMART |
|
Blast:WD40
|
1466 |
1507 |
3e-19 |
BLAST |
|
Blast:WD40
|
1606 |
1644 |
4e-18 |
BLAST |
|
Blast:KR
|
1686 |
1730 |
2e-16 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162166
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162757
|
| Meta Mutation Damage Score |
0.1843 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.1%
|
| Validation Efficiency |
98% (119/121) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 117 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
T |
C |
11: 9,241,058 (GRCm39) |
Y974H |
probably benign |
Het |
| Abca2 |
G |
T |
2: 25,324,906 (GRCm39) |
G300V |
probably benign |
Het |
| Abi1 |
A |
G |
2: 22,852,516 (GRCm39) |
|
probably benign |
Het |
| Actr10 |
T |
A |
12: 71,006,738 (GRCm39) |
Y332N |
probably damaging |
Het |
| Adam25 |
G |
T |
8: 41,208,261 (GRCm39) |
C509F |
probably damaging |
Het |
| Adck1 |
A |
T |
12: 88,338,461 (GRCm39) |
|
probably benign |
Het |
| Adgra3 |
A |
G |
5: 50,166,676 (GRCm39) |
|
probably null |
Het |
| Adgrl1 |
G |
T |
8: 84,661,279 (GRCm39) |
|
probably benign |
Het |
| Akr1c21 |
A |
G |
13: 4,626,306 (GRCm39) |
Y110C |
probably damaging |
Het |
| Arhgef25 |
T |
C |
10: 127,019,566 (GRCm39) |
I463V |
probably null |
Het |
| Atp6v1e2 |
C |
T |
17: 87,252,006 (GRCm39) |
V131M |
probably benign |
Het |
| Bdnf |
A |
G |
2: 109,505,688 (GRCm39) |
|
probably null |
Het |
| Bltp3b |
T |
C |
10: 89,627,305 (GRCm39) |
S145P |
probably damaging |
Het |
| C7 |
A |
T |
15: 5,023,624 (GRCm39) |
|
probably benign |
Het |
| Cdc27 |
T |
C |
11: 104,419,114 (GRCm39) |
T273A |
probably benign |
Het |
| Cdo1 |
T |
A |
18: 46,848,678 (GRCm39) |
I187F |
probably benign |
Het |
| Cep104 |
A |
T |
4: 154,080,761 (GRCm39) |
T742S |
probably benign |
Het |
| Ckm |
A |
T |
7: 19,153,377 (GRCm39) |
K223* |
probably null |
Het |
| Cmtr1 |
C |
T |
17: 29,895,259 (GRCm39) |
P586L |
probably benign |
Het |
| Csmd1 |
C |
T |
8: 16,042,758 (GRCm39) |
R2325Q |
probably damaging |
Het |
| Dcpp1 |
A |
T |
17: 24,101,568 (GRCm39) |
I106L |
possibly damaging |
Het |
| Diaph3 |
A |
C |
14: 87,328,400 (GRCm39) |
|
probably benign |
Het |
| Dnah11 |
A |
G |
12: 118,070,245 (GRCm39) |
V1520A |
probably damaging |
Het |
| Dnajc25 |
T |
A |
4: 59,020,438 (GRCm39) |
M168K |
|
Het |
| Dpp3 |
T |
C |
19: 4,964,682 (GRCm39) |
N542D |
probably damaging |
Het |
| Ebf2 |
A |
T |
14: 67,609,185 (GRCm39) |
K199* |
probably null |
Het |
| Eeig2 |
T |
C |
3: 108,887,520 (GRCm39) |
E248G |
probably benign |
Het |
| Efcab11 |
T |
A |
12: 99,685,294 (GRCm39) |
Q160L |
probably benign |
Het |
| Eif2ak4 |
T |
A |
2: 118,261,517 (GRCm39) |
S686T |
probably benign |
Het |
| Epha6 |
C |
T |
16: 60,026,095 (GRCm39) |
S449N |
possibly damaging |
Het |
| Ercc4 |
T |
C |
16: 12,944,331 (GRCm39) |
V329A |
probably benign |
Het |
| Faf1 |
T |
C |
4: 109,697,600 (GRCm39) |
F309L |
possibly damaging |
Het |
| G6pd2 |
C |
A |
5: 61,966,910 (GRCm39) |
D228E |
probably benign |
Het |
| Ggt1 |
T |
G |
10: 75,421,791 (GRCm39) |
V546G |
probably damaging |
Het |
| Gpatch4 |
G |
T |
3: 87,958,524 (GRCm39) |
V3F |
probably damaging |
Het |
| Gprin3 |
A |
G |
6: 59,330,372 (GRCm39) |
L645P |
probably damaging |
Het |
| Hyal2 |
A |
G |
9: 107,449,270 (GRCm39) |
Y342C |
probably benign |
Het |
| Igf2bp2 |
A |
G |
16: 21,907,849 (GRCm39) |
I16T |
possibly damaging |
Het |
| Inca1 |
T |
C |
11: 70,581,025 (GRCm39) |
Y61C |
probably damaging |
Het |
| Ipo5 |
T |
C |
14: 121,180,145 (GRCm39) |
W860R |
possibly damaging |
Het |
| Kcnj9 |
C |
T |
1: 172,150,591 (GRCm39) |
A341T |
probably benign |
Het |
| Kdm5b |
T |
C |
1: 134,530,309 (GRCm39) |
V440A |
probably damaging |
Het |
| L3mbtl1 |
C |
T |
2: 162,789,255 (GRCm39) |
|
probably benign |
Het |
| Lin54 |
G |
A |
5: 100,600,152 (GRCm39) |
T307I |
probably damaging |
Het |
| Lrrc18 |
C |
A |
14: 32,731,096 (GRCm39) |
Q212K |
probably benign |
Het |
| Lrrc37a |
A |
G |
11: 103,393,851 (GRCm39) |
S525P |
probably benign |
Het |
| Lrrc71 |
T |
A |
3: 87,653,006 (GRCm39) |
S137C |
probably damaging |
Het |
| Lrrk1 |
A |
T |
7: 65,940,656 (GRCm39) |
|
probably null |
Het |
| Man2b2 |
G |
A |
5: 36,973,542 (GRCm39) |
S58L |
probably benign |
Het |
| Masp1 |
T |
A |
16: 23,276,888 (GRCm39) |
H539L |
probably benign |
Het |
| Med1 |
G |
A |
11: 98,047,730 (GRCm39) |
P1022L |
probably damaging |
Het |
| Meis1 |
T |
A |
11: 18,961,360 (GRCm39) |
H171L |
probably damaging |
Het |
| Mier1 |
T |
A |
4: 103,012,820 (GRCm39) |
|
probably benign |
Het |
| Mmp13 |
A |
T |
9: 7,272,929 (GRCm39) |
R96S |
probably damaging |
Het |
| Mms19 |
G |
A |
19: 41,942,173 (GRCm39) |
T38I |
probably damaging |
Het |
| Mrc1 |
G |
A |
2: 14,314,843 (GRCm39) |
C976Y |
probably damaging |
Het |
| Mrtfb |
C |
T |
16: 13,230,390 (GRCm39) |
T1025I |
possibly damaging |
Het |
| Naalad2 |
A |
G |
9: 18,297,191 (GRCm39) |
Y32H |
probably benign |
Het |
| Ndufs1 |
A |
G |
1: 63,183,085 (GRCm39) |
|
probably benign |
Het |
| Nefm |
C |
T |
14: 68,361,608 (GRCm39) |
D219N |
probably damaging |
Het |
| Nwd1 |
C |
T |
8: 73,388,965 (GRCm39) |
P172L |
probably damaging |
Het |
| Ogdh |
T |
A |
11: 6,289,936 (GRCm39) |
|
probably benign |
Het |
| Olfm3 |
T |
A |
3: 114,916,330 (GRCm39) |
S421T |
possibly damaging |
Het |
| Opn5 |
T |
G |
17: 42,903,844 (GRCm39) |
T164P |
possibly damaging |
Het |
| Or4k37 |
A |
T |
2: 111,159,673 (GRCm39) |
N303I |
probably benign |
Het |
| Or51a25 |
T |
A |
7: 102,373,236 (GRCm39) |
I154F |
probably damaging |
Het |
| Or52a24 |
T |
C |
7: 103,381,583 (GRCm39) |
V150A |
probably benign |
Het |
| Or5ak20 |
A |
G |
2: 85,184,093 (GRCm39) |
M59T |
possibly damaging |
Het |
| Or5b12b |
T |
C |
19: 12,861,443 (GRCm39) |
L66P |
probably damaging |
Het |
| Or5b12b |
A |
G |
19: 12,861,910 (GRCm39) |
T222A |
probably damaging |
Het |
| Pde7b |
C |
T |
10: 20,314,492 (GRCm39) |
V166M |
probably damaging |
Het |
| Peds1 |
A |
T |
2: 167,486,907 (GRCm39) |
|
probably benign |
Het |
| Pik3ap1 |
T |
C |
19: 41,313,003 (GRCm39) |
N370S |
probably damaging |
Het |
| Pkhd1l1 |
A |
T |
15: 44,452,814 (GRCm39) |
D3913V |
probably damaging |
Het |
| Pld1 |
A |
G |
3: 28,174,971 (GRCm39) |
I90V |
possibly damaging |
Het |
| Plxna2 |
A |
G |
1: 194,326,656 (GRCm39) |
T197A |
possibly damaging |
Het |
| Plxna4 |
A |
T |
6: 32,179,054 (GRCm39) |
M987K |
probably benign |
Het |
| Pmch |
A |
G |
10: 87,927,221 (GRCm39) |
N75D |
probably benign |
Het |
| Prom2 |
T |
A |
2: 127,374,787 (GRCm39) |
Q583L |
possibly damaging |
Het |
| Pyroxd1 |
T |
A |
6: 142,299,288 (GRCm39) |
M148K |
possibly damaging |
Het |
| R3hdm2 |
C |
T |
10: 127,293,569 (GRCm39) |
L158F |
probably damaging |
Het |
| Rapgef6 |
A |
T |
11: 54,516,789 (GRCm39) |
T349S |
probably benign |
Het |
| Rfx5 |
C |
T |
3: 94,863,666 (GRCm39) |
T105I |
probably damaging |
Het |
| Rif1 |
C |
A |
2: 52,000,749 (GRCm39) |
P1401Q |
probably damaging |
Het |
| Robo3 |
G |
A |
9: 37,328,055 (GRCm39) |
|
probably benign |
Het |
| Rpn1 |
T |
A |
6: 88,067,224 (GRCm39) |
S195T |
probably benign |
Het |
| Rslcan18 |
C |
A |
13: 67,250,183 (GRCm39) |
K17N |
probably benign |
Het |
| Rsph3b |
A |
T |
17: 7,209,126 (GRCm39) |
I48N |
probably damaging |
Het |
| Sbf2 |
A |
T |
7: 109,998,550 (GRCm39) |
Y628N |
probably damaging |
Het |
| Sis |
T |
C |
3: 72,867,629 (GRCm39) |
T139A |
probably benign |
Het |
| Slc22a14 |
A |
G |
9: 119,001,100 (GRCm39) |
|
probably benign |
Het |
| Slitrk6 |
A |
T |
14: 110,987,364 (GRCm39) |
L781H |
probably damaging |
Het |
| Smarcb1 |
T |
C |
10: 75,732,900 (GRCm39) |
T372A |
probably damaging |
Het |
| Spidr |
T |
A |
16: 15,855,531 (GRCm39) |
H328L |
probably damaging |
Het |
| Sun5 |
T |
A |
2: 153,712,872 (GRCm39) |
D16V |
probably damaging |
Het |
| Syde2 |
G |
A |
3: 145,720,135 (GRCm39) |
E1053K |
possibly damaging |
Het |
| Syne2 |
T |
C |
12: 76,146,238 (GRCm39) |
S6419P |
probably damaging |
Het |
| Tenm3 |
G |
A |
8: 48,794,195 (GRCm39) |
|
probably benign |
Het |
| Timm44 |
C |
A |
8: 4,310,532 (GRCm39) |
E407* |
probably null |
Het |
| Tnpo2 |
A |
G |
8: 85,773,991 (GRCm39) |
T342A |
probably benign |
Het |
| Trio |
A |
G |
15: 27,767,993 (GRCm39) |
C1964R |
probably benign |
Het |
| Trip11 |
A |
C |
12: 101,851,931 (GRCm39) |
L711R |
probably damaging |
Het |
| Trp53bp1 |
A |
T |
2: 121,100,450 (GRCm39) |
H101Q |
probably damaging |
Het |
| Trpm6 |
A |
G |
19: 18,851,266 (GRCm39) |
|
probably benign |
Het |
| Ttn |
A |
T |
2: 76,680,335 (GRCm39) |
|
probably benign |
Het |
| Ucp1 |
T |
A |
8: 84,021,936 (GRCm39) |
M256K |
possibly damaging |
Het |
| Unc5a |
T |
A |
13: 55,152,767 (GRCm39) |
S838T |
probably damaging |
Het |
| Uxs1 |
T |
C |
1: 43,804,046 (GRCm39) |
|
probably null |
Het |
| Vmn2r108 |
A |
T |
17: 20,683,096 (GRCm39) |
C703S |
possibly damaging |
Het |
| Zc3hav1 |
C |
T |
6: 38,309,599 (GRCm39) |
G408R |
probably damaging |
Het |
| Zfp1004 |
T |
A |
2: 150,035,000 (GRCm39) |
C471* |
probably null |
Het |
| Zfp609 |
G |
A |
9: 65,610,744 (GRCm39) |
L740F |
possibly damaging |
Het |
| Zfp69 |
T |
C |
4: 120,788,292 (GRCm39) |
E341G |
probably damaging |
Het |
| Zfp707 |
A |
T |
15: 75,847,105 (GRCm39) |
H312L |
probably damaging |
Het |
| Zfp773 |
T |
C |
7: 7,136,023 (GRCm39) |
D191G |
probably benign |
Het |
| Zgrf1 |
C |
A |
3: 127,366,887 (GRCm39) |
D755E |
probably benign |
Het |
| Zscan5b |
T |
A |
7: 6,242,074 (GRCm39) |
I431N |
probably damaging |
Het |
|
| Other mutations in Nwd2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Nwd2
|
APN |
5 |
63,962,818 (GRCm39) |
missense |
probably benign |
|
|
IGL01111:Nwd2
|
APN |
5 |
63,964,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01152:Nwd2
|
APN |
5 |
63,963,872 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01307:Nwd2
|
APN |
5 |
63,965,626 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01449:Nwd2
|
APN |
5 |
63,962,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01624:Nwd2
|
APN |
5 |
63,964,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01997:Nwd2
|
APN |
5 |
63,961,938 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02007:Nwd2
|
APN |
5 |
63,962,042 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02143:Nwd2
|
APN |
5 |
63,948,996 (GRCm39) |
splice site |
probably null |
|
|
IGL02184:Nwd2
|
APN |
5 |
63,963,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02379:Nwd2
|
APN |
5 |
63,962,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02489:Nwd2
|
APN |
5 |
63,962,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02580:Nwd2
|
APN |
5 |
63,965,512 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02682:Nwd2
|
APN |
5 |
63,962,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02682:Nwd2
|
APN |
5 |
63,962,020 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02891:Nwd2
|
APN |
5 |
63,882,570 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03135:Nwd2
|
APN |
5 |
63,963,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03149:Nwd2
|
APN |
5 |
63,963,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0113:Nwd2
|
UTSW |
5 |
63,965,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0172:Nwd2
|
UTSW |
5 |
63,963,712 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0196:Nwd2
|
UTSW |
5 |
63,963,694 (GRCm39) |
missense |
probably benign |
0.37 |
|
R0239:Nwd2
|
UTSW |
5 |
63,957,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0239:Nwd2
|
UTSW |
5 |
63,957,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0309:Nwd2
|
UTSW |
5 |
63,964,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0311:Nwd2
|
UTSW |
5 |
63,962,341 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0335:Nwd2
|
UTSW |
5 |
63,962,116 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0384:Nwd2
|
UTSW |
5 |
63,963,025 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0496:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0497:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0498:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0655:Nwd2
|
UTSW |
5 |
63,948,928 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0762:Nwd2
|
UTSW |
5 |
63,957,757 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0835:Nwd2
|
UTSW |
5 |
63,957,473 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0926:Nwd2
|
UTSW |
5 |
63,965,234 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0948:Nwd2
|
UTSW |
5 |
63,964,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1015:Nwd2
|
UTSW |
5 |
63,964,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1086:Nwd2
|
UTSW |
5 |
63,963,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1186:Nwd2
|
UTSW |
5 |
63,807,367 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1305:Nwd2
|
UTSW |
5 |
63,902,540 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1542:Nwd2
|
UTSW |
5 |
63,964,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1548:Nwd2
|
UTSW |
5 |
63,957,525 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1553:Nwd2
|
UTSW |
5 |
63,957,848 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1636:Nwd2
|
UTSW |
5 |
63,964,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1658:Nwd2
|
UTSW |
5 |
63,964,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Nwd2
|
UTSW |
5 |
63,965,614 (GRCm39) |
missense |
probably benign |
|
|
R1800:Nwd2
|
UTSW |
5 |
63,962,917 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1813:Nwd2
|
UTSW |
5 |
63,962,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1861:Nwd2
|
UTSW |
5 |
63,962,197 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1889:Nwd2
|
UTSW |
5 |
63,965,009 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1896:Nwd2
|
UTSW |
5 |
63,962,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1919:Nwd2
|
UTSW |
5 |
63,963,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1922:Nwd2
|
UTSW |
5 |
63,951,585 (GRCm39) |
missense |
probably benign |
|
|
R2258:Nwd2
|
UTSW |
5 |
63,962,499 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2292:Nwd2
|
UTSW |
5 |
63,962,917 (GRCm39) |
missense |
probably benign |
0.15 |
|
R2504:Nwd2
|
UTSW |
5 |
63,961,717 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2869:Nwd2
|
UTSW |
5 |
63,957,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2869:Nwd2
|
UTSW |
5 |
63,957,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2958:Nwd2
|
UTSW |
5 |
63,963,325 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3034:Nwd2
|
UTSW |
5 |
63,957,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3422:Nwd2
|
UTSW |
5 |
63,882,536 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3423:Nwd2
|
UTSW |
5 |
63,957,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3439:Nwd2
|
UTSW |
5 |
63,961,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4193:Nwd2
|
UTSW |
5 |
63,964,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4254:Nwd2
|
UTSW |
5 |
63,963,889 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R4384:Nwd2
|
UTSW |
5 |
63,963,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Nwd2
|
UTSW |
5 |
63,951,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4713:Nwd2
|
UTSW |
5 |
63,961,803 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4735:Nwd2
|
UTSW |
5 |
63,965,594 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4744:Nwd2
|
UTSW |
5 |
63,964,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4795:Nwd2
|
UTSW |
5 |
63,962,776 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4835:Nwd2
|
UTSW |
5 |
63,965,189 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4839:Nwd2
|
UTSW |
5 |
63,962,893 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4896:Nwd2
|
UTSW |
5 |
63,962,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5017:Nwd2
|
UTSW |
5 |
63,807,484 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5170:Nwd2
|
UTSW |
5 |
63,963,380 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5312:Nwd2
|
UTSW |
5 |
63,963,415 (GRCm39) |
nonsense |
probably null |
|
|
R5330:Nwd2
|
UTSW |
5 |
63,963,859 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5331:Nwd2
|
UTSW |
5 |
63,963,859 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5419:Nwd2
|
UTSW |
5 |
63,965,051 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5434:Nwd2
|
UTSW |
5 |
63,964,991 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5445:Nwd2
|
UTSW |
5 |
63,962,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Nwd2
|
UTSW |
5 |
63,882,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5788:Nwd2
|
UTSW |
5 |
63,965,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5907:Nwd2
|
UTSW |
5 |
63,963,326 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5959:Nwd2
|
UTSW |
5 |
63,965,413 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6002:Nwd2
|
UTSW |
5 |
63,962,143 (GRCm39) |
missense |
probably benign |
|
|
R6027:Nwd2
|
UTSW |
5 |
63,965,563 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6082:Nwd2
|
UTSW |
5 |
63,962,374 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6163:Nwd2
|
UTSW |
5 |
63,963,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6172:Nwd2
|
UTSW |
5 |
63,964,249 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6334:Nwd2
|
UTSW |
5 |
63,957,596 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6447:Nwd2
|
UTSW |
5 |
63,964,898 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6649:Nwd2
|
UTSW |
5 |
63,882,527 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6855:Nwd2
|
UTSW |
5 |
63,961,794 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7034:Nwd2
|
UTSW |
5 |
63,962,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7168:Nwd2
|
UTSW |
5 |
63,964,837 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7326:Nwd2
|
UTSW |
5 |
63,957,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7561:Nwd2
|
UTSW |
5 |
63,964,434 (GRCm39) |
nonsense |
probably null |
|
|
R7576:Nwd2
|
UTSW |
5 |
63,964,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7580:Nwd2
|
UTSW |
5 |
63,965,624 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7723:Nwd2
|
UTSW |
5 |
63,965,347 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7769:Nwd2
|
UTSW |
5 |
63,961,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8293:Nwd2
|
UTSW |
5 |
63,962,663 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8517:Nwd2
|
UTSW |
5 |
63,948,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8782:Nwd2
|
UTSW |
5 |
63,882,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8792:Nwd2
|
UTSW |
5 |
63,963,047 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8888:Nwd2
|
UTSW |
5 |
63,963,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8895:Nwd2
|
UTSW |
5 |
63,963,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8901:Nwd2
|
UTSW |
5 |
63,963,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8913:Nwd2
|
UTSW |
5 |
63,963,440 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8920:Nwd2
|
UTSW |
5 |
63,948,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9052:Nwd2
|
UTSW |
5 |
63,961,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Nwd2
|
UTSW |
5 |
63,961,747 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9368:Nwd2
|
UTSW |
5 |
63,962,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9377:Nwd2
|
UTSW |
5 |
63,957,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9430:Nwd2
|
UTSW |
5 |
63,964,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Nwd2
|
UTSW |
5 |
63,964,568 (GRCm39) |
nonsense |
probably null |
|
|
R9661:Nwd2
|
UTSW |
5 |
63,957,780 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9736:Nwd2
|
UTSW |
5 |
63,951,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9793:Nwd2
|
UTSW |
5 |
63,964,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9795:Nwd2
|
UTSW |
5 |
63,964,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF020:Nwd2
|
UTSW |
5 |
63,963,066 (GRCm39) |
nonsense |
probably null |
|
|
X0023:Nwd2
|
UTSW |
5 |
63,964,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Nwd2
|
UTSW |
5 |
63,963,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Nwd2
|
UTSW |
5 |
63,882,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nwd2
|
UTSW |
5 |
63,964,669 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Nwd2
|
UTSW |
5 |
63,962,327 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGAGTCCTCCCTCTGTGTGACTG -3'
(R):5'- AAGTCGAGGCAGCCATTCAAGTAG -3'
Sequencing Primer
(F):5'- CTGTGTGACTGTCCACGAAAG -3'
(R):5'- CCATTCAAGTAGGGGTCTTCCAG -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation