Mutagenetix > Incidental Mutation

Incidental Mutation 'R3958:Gm6522'

474933

Institutional Source

Beutler Lab

Gene Symbol

Gm6522

Ensembl Gene

Gene Name

predicted gene 6522

Synonyms

MMRRC Submission

040834-MU

Accession Numbers

Essential gene?

Not available question?

Stock #

R3958 (G1)

Quality Score

Status

Not validated

Chromosome

Chromosomal Location

106183060-106206343 bp(+) (GRCm39)

Type of Mutation

critical splice donor site

DNA Base Change (assembly)

T to C at 106206120 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000197160

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.8%
20x: 93.3%

Validation Efficiency

100% (37/37)

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Actl9	A	G	17: 33,652,738 (GRCm39)	K266R	probably benign	Het
Cebpd	T	C	16: 15,705,327 (GRCm39)	S47P	possibly damaging	Het
Celf4	A	G	18: 25,670,811 (GRCm39)	M124T	probably benign	Het
Ckap4	C	T	10: 84,364,028 (GRCm39)	R345H	probably benign	Het
Clasp1	T	C	1: 118,395,611 (GRCm39)	V183A	probably damaging	Het
Cyp2s1	C	T	7: 25,503,379 (GRCm39)	R424Q	probably null	Het
Espl1	A	G	15: 102,221,424 (GRCm39)	I944V	probably damaging	Het
Etl4	A	G	2: 20,344,854 (GRCm39)	T53A	probably benign	Het
Glyat	A	T	19: 12,617,197 (GRCm39)	K16N	probably benign	Het
Grin1	G	A	2: 25,203,465 (GRCm39)	T182M	probably damaging	Het
Hcn4	T	C	9: 58,751,331 (GRCm39)	V319A	unknown	Het
Hmgcs2	T	C	3: 98,204,793 (GRCm39)	F317S	possibly damaging	Het
Hoxd8	C	T	2: 74,536,884 (GRCm39)	Q18*	probably null	Het
Itpr2	C	T	6: 146,327,008 (GRCm39)	V120I	probably damaging	Het
Kmt2d	G	A	15: 98,753,430 (GRCm39)	T141M	possibly damaging	Het
Lrp1	A	G	10: 127,407,827 (GRCm39)	S1821P	probably benign	Het
Neb	T	C	2: 52,153,641 (GRCm39)	E2428G	probably damaging	Het
Nepn	T	C	10: 52,276,804 (GRCm39)	V119A	probably benign	Het
Or4k41	G	T	2: 111,280,230 (GRCm39)	L248F	possibly damaging	Het
Otogl	T	C	10: 107,657,786 (GRCm39)	D1048G	probably damaging	Het
Panx1	GTTCTTCT	GTTCT	9: 14,917,467 (GRCm39)		probably benign	Het
Ppp6r3	A	T	19: 3,546,583 (GRCm39)	V305D	probably damaging	Het
Prkg2	G	T	5: 99,145,354 (GRCm39)	T160K	possibly damaging	Het
Prmt8	G	A	6: 127,709,707 (GRCm39)	T51I	probably benign	Het
Rgl3	T	C	9: 21,886,885 (GRCm39)		probably benign	Het
Sec23ip	C	G	7: 128,378,574 (GRCm39)	T796S	probably benign	Het
Selp	T	C	1: 163,953,855 (GRCm39)	S52P	probably benign	Het
Slc44a2	T	C	9: 21,259,837 (GRCm39)	I615T	probably damaging	Het
Snap91	T	C	9: 86,720,183 (GRCm39)	Y118C	probably damaging	Het
Tmem106b	A	T	6: 13,081,587 (GRCm39)	N165Y	probably damaging	Het
Ucp3	A	G	7: 100,131,946 (GRCm39)	T266A	probably benign	Het
Ugcg	C	T	4: 59,207,798 (GRCm39)	P46S	probably benign	Het
Utrn	T	C	10: 12,625,852 (GRCm39)	I110V	probably damaging	Het

Other mutations in Gm6522

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R4865:Gm6522	UTSW	3	106,183,286 (GRCm39)	critical splice donor site	noncoding transcript

Predicted Primers

Posted On

2017-04-14