Incidental Mutation 'R0506:Parp14'
| ID |
47619 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Parp14
|
| Ensembl Gene |
ENSMUSG00000034422 |
| Gene Name |
poly (ADP-ribose) polymerase family, member 14 |
| Synonyms |
CoaSt6, collaborator of Stat6, 1600029O10Rik |
| MMRRC Submission |
038701-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.466)
|
| Stock # |
R0506 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
35653244-35691914 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 35661779 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 1419
(S1419T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037657
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042665]
|
| AlphaFold |
Q2EMV9 |
| PDB Structure |
Solution structure of WWE domain in Parp14 protein [SOLUTION NMR]
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000042665
AA Change: S1419T
PolyPhen 2
Score 0.700 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000037657
Gene: ENSMUSG00000034422
AA Change: S1419T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
38 |
49 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
115 |
N/A |
INTRINSIC |
|
RRM
|
228 |
297 |
4.71e-2 |
SMART |
|
coiled coil region
|
443 |
468 |
N/A |
INTRINSIC |
|
Blast:A1pp
|
693 |
746 |
6e-6 |
BLAST |
|
low complexity region
|
771 |
795 |
N/A |
INTRINSIC |
|
A1pp
|
814 |
948 |
7.62e-41 |
SMART |
|
A1pp
|
1026 |
1160 |
5.88e-24 |
SMART |
|
A1pp
|
1239 |
1358 |
6.82e-20 |
SMART |
|
PDB:1X4R|A
|
1532 |
1619 |
9e-53 |
PDB |
|
Pfam:PARP
|
1632 |
1817 |
2.5e-29 |
PFAM |
|
| Meta Mutation Damage Score |
0.2085 |
| Coding Region Coverage |
- 1x: 99.6%
- 3x: 98.8%
- 10x: 96.7%
- 20x: 93.3%
|
| Validation Efficiency |
100% (100/100) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the poly(ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit altered B cell subsets and inability to respond to the apoptosis protective affects of IL4. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acsm5 |
T |
A |
7: 119,137,319 (GRCm39) |
C378* |
probably null |
Het |
| Ago3 |
T |
C |
4: 126,311,045 (GRCm39) |
D56G |
possibly damaging |
Het |
| Ahnak |
G |
T |
19: 8,986,492 (GRCm39) |
G2592V |
probably damaging |
Het |
| Aldh6a1 |
C |
T |
12: 84,480,300 (GRCm39) |
G470D |
probably damaging |
Het |
| Ankub1 |
T |
A |
3: 57,597,796 (GRCm39) |
N58I |
probably damaging |
Het |
| Apol7b |
G |
T |
15: 77,309,728 (GRCm39) |
T23K |
probably benign |
Het |
| Arap2 |
G |
A |
5: 62,763,474 (GRCm39) |
P1557S |
possibly damaging |
Het |
| Arhgap24 |
T |
C |
5: 103,023,643 (GRCm39) |
Y136H |
probably damaging |
Het |
| Atp1a1 |
A |
G |
3: 101,497,128 (GRCm39) |
F393L |
probably damaging |
Het |
| Bcdin3d |
A |
T |
15: 99,368,873 (GRCm39) |
C109S |
probably damaging |
Het |
| Catsperd |
A |
G |
17: 56,965,078 (GRCm39) |
K475R |
possibly damaging |
Het |
| Cblb |
A |
G |
16: 52,024,843 (GRCm39) |
T913A |
probably benign |
Het |
| Cbx6 |
A |
G |
15: 79,712,404 (GRCm39) |
L341P |
probably benign |
Het |
| Cd177 |
T |
C |
7: 24,457,781 (GRCm39) |
Y159C |
probably damaging |
Het |
| Cdh20 |
A |
G |
1: 110,027,844 (GRCm39) |
N530D |
probably damaging |
Het |
| Cdk8 |
T |
C |
5: 146,235,682 (GRCm39) |
F270L |
probably damaging |
Het |
| Ces2c |
A |
T |
8: 105,574,656 (GRCm39) |
T38S |
probably damaging |
Het |
| Chst14 |
T |
C |
2: 118,758,202 (GRCm39) |
L357P |
probably damaging |
Het |
| Clca3b |
T |
A |
3: 144,528,627 (GRCm39) |
|
probably benign |
Het |
| Cluh |
A |
G |
11: 74,555,720 (GRCm39) |
S839G |
probably benign |
Het |
| Cnga4 |
T |
A |
7: 105,056,947 (GRCm39) |
V350E |
probably damaging |
Het |
| Creb1 |
G |
A |
1: 64,609,426 (GRCm39) |
G180R |
probably damaging |
Het |
| Csmd3 |
T |
C |
15: 48,320,907 (GRCm39) |
E301G |
probably benign |
Het |
| Cyp4f18 |
A |
T |
8: 72,749,844 (GRCm39) |
D268E |
probably benign |
Het |
| Dock5 |
A |
G |
14: 68,022,241 (GRCm39) |
|
probably benign |
Het |
| Dpy19l4 |
T |
A |
4: 11,289,715 (GRCm39) |
H332L |
probably benign |
Het |
| Dync2h1 |
T |
A |
9: 7,113,153 (GRCm39) |
H224L |
probably benign |
Het |
| Dzip1l |
C |
A |
9: 99,545,134 (GRCm39) |
Q585K |
possibly damaging |
Het |
| Erf |
C |
T |
7: 24,943,801 (GRCm39) |
G510D |
probably damaging |
Het |
| Fanci |
T |
C |
7: 79,081,926 (GRCm39) |
L623P |
probably benign |
Het |
| Fat1 |
T |
C |
8: 45,475,988 (GRCm39) |
V1655A |
probably damaging |
Het |
| Fat4 |
T |
C |
3: 38,942,463 (GRCm39) |
V452A |
probably benign |
Het |
| Gal3st4 |
C |
T |
5: 138,264,151 (GRCm39) |
G283S |
probably benign |
Het |
| Gm5422 |
A |
G |
10: 31,126,318 (GRCm39) |
|
noncoding transcript |
Het |
| Gnal |
C |
T |
18: 67,221,744 (GRCm39) |
T49I |
unknown |
Het |
| Gng5 |
A |
G |
3: 146,209,103 (GRCm39) |
N57S |
probably damaging |
Het |
| Herc1 |
A |
G |
9: 66,355,441 (GRCm39) |
I2231V |
probably damaging |
Het |
| Hgfac |
G |
T |
5: 35,201,584 (GRCm39) |
G272W |
probably damaging |
Het |
| Hmcn1 |
T |
A |
1: 150,618,092 (GRCm39) |
D1265V |
possibly damaging |
Het |
| Ifi207 |
T |
A |
1: 173,563,878 (GRCm39) |
Q47L |
possibly damaging |
Het |
| Klhl40 |
G |
A |
9: 121,607,133 (GRCm39) |
E98K |
probably damaging |
Het |
| Lepr |
G |
T |
4: 101,630,207 (GRCm39) |
|
probably benign |
Het |
| Lyst |
A |
G |
13: 13,812,600 (GRCm39) |
H1004R |
probably benign |
Het |
| Map3k1 |
T |
A |
13: 111,892,298 (GRCm39) |
R986* |
probably null |
Het |
| Mmp1b |
C |
A |
9: 7,387,013 (GRCm39) |
Q66H |
possibly damaging |
Het |
| Mpo |
T |
C |
11: 87,694,330 (GRCm39) |
S107P |
probably benign |
Het |
| Mroh9 |
T |
C |
1: 162,888,205 (GRCm39) |
H290R |
possibly damaging |
Het |
| Myo7b |
A |
G |
18: 32,097,439 (GRCm39) |
|
probably null |
Het |
| Myom1 |
T |
C |
17: 71,399,215 (GRCm39) |
|
probably benign |
Het |
| Nalcn |
C |
T |
14: 123,834,026 (GRCm39) |
V50I |
possibly damaging |
Het |
| Negr1 |
A |
G |
3: 156,866,385 (GRCm39) |
|
probably benign |
Het |
| Nlrc5 |
T |
G |
8: 95,219,753 (GRCm39) |
|
probably benign |
Het |
| Nyap2 |
G |
A |
1: 81,065,029 (GRCm39) |
D14N |
probably damaging |
Het |
| Or10w1 |
T |
A |
19: 13,632,261 (GRCm39) |
I151N |
possibly damaging |
Het |
| Or2h1 |
C |
A |
17: 37,404,203 (GRCm39) |
G188W |
probably damaging |
Het |
| Or5b105 |
G |
A |
19: 13,080,642 (GRCm39) |
R3C |
possibly damaging |
Het |
| Piezo2 |
A |
G |
18: 63,160,615 (GRCm39) |
F2347S |
probably damaging |
Het |
| Pigf |
A |
G |
17: 87,316,337 (GRCm39) |
V147A |
probably benign |
Het |
| Pkhd1 |
A |
T |
1: 20,629,693 (GRCm39) |
M637K |
probably benign |
Het |
| Plce1 |
T |
C |
19: 38,748,582 (GRCm39) |
I1771T |
probably benign |
Het |
| Ppp6c |
A |
T |
2: 39,096,660 (GRCm39) |
|
probably benign |
Het |
| Prag1 |
T |
C |
8: 36,570,854 (GRCm39) |
V479A |
possibly damaging |
Het |
| Prss33 |
A |
T |
17: 24,054,079 (GRCm39) |
D42E |
probably benign |
Het |
| Psmb10 |
A |
G |
8: 106,664,177 (GRCm39) |
V64A |
possibly damaging |
Het |
| Psmd14 |
A |
G |
2: 61,630,407 (GRCm39) |
T306A |
probably benign |
Het |
| Psmg1 |
C |
T |
16: 95,790,687 (GRCm39) |
|
probably benign |
Het |
| Rc3h2 |
A |
T |
2: 37,266,671 (GRCm39) |
|
probably null |
Het |
| Reln |
C |
T |
5: 22,125,494 (GRCm39) |
V2730I |
probably damaging |
Het |
| Sec24a |
A |
T |
11: 51,634,622 (GRCm39) |
H101Q |
probably benign |
Het |
| Selenoi |
A |
G |
5: 30,471,954 (GRCm39) |
N385S |
probably benign |
Het |
| Slc24a4 |
T |
C |
12: 102,097,882 (GRCm39) |
|
probably null |
Het |
| Slc4a10 |
G |
A |
2: 62,080,877 (GRCm39) |
S338N |
probably benign |
Het |
| Slfn3 |
A |
T |
11: 83,103,986 (GRCm39) |
T286S |
probably damaging |
Het |
| Snx29 |
A |
G |
16: 11,213,167 (GRCm39) |
D111G |
probably benign |
Het |
| Sp8 |
T |
C |
12: 118,812,300 (GRCm39) |
S52P |
possibly damaging |
Het |
| Srek1 |
G |
T |
13: 103,897,098 (GRCm39) |
T81K |
probably damaging |
Het |
| Sry |
C |
G |
Y: 2,662,864 (GRCm39) |
Q265H |
unknown |
Het |
| Taf3 |
A |
G |
2: 9,945,804 (GRCm39) |
V600A |
probably benign |
Het |
| Tatdn2 |
C |
A |
6: 113,679,550 (GRCm39) |
D298E |
probably benign |
Het |
| Tmem253 |
A |
T |
14: 52,254,663 (GRCm39) |
|
probably benign |
Het |
| Tmem63a |
T |
A |
1: 180,785,614 (GRCm39) |
|
probably null |
Het |
| Tmprss11b |
T |
C |
5: 86,809,499 (GRCm39) |
D331G |
probably damaging |
Het |
| Tor1aip1 |
T |
A |
1: 155,883,420 (GRCm39) |
K143* |
probably null |
Het |
| Trappc8 |
A |
T |
18: 20,977,245 (GRCm39) |
N841K |
possibly damaging |
Het |
| Trio |
T |
C |
15: 27,855,049 (GRCm39) |
Q711R |
probably benign |
Het |
| Trmt10b |
C |
A |
4: 45,304,306 (GRCm39) |
T114N |
probably damaging |
Het |
| Trpv2 |
C |
A |
11: 62,473,732 (GRCm39) |
A129D |
probably benign |
Het |
| Ttll4 |
T |
G |
1: 74,727,777 (GRCm39) |
D846E |
probably benign |
Het |
| Ugt2a3 |
A |
G |
5: 87,484,508 (GRCm39) |
L172P |
possibly damaging |
Het |
| Usp19 |
T |
A |
9: 108,371,686 (GRCm39) |
F355Y |
probably damaging |
Het |
| Vmn1r209 |
C |
T |
13: 22,990,114 (GRCm39) |
G192D |
probably damaging |
Het |
| Vmn2r107 |
T |
G |
17: 20,578,021 (GRCm39) |
D443E |
probably benign |
Het |
| Wee2 |
A |
T |
6: 40,440,187 (GRCm39) |
E445V |
probably benign |
Het |
| Zer1 |
A |
T |
2: 29,991,819 (GRCm39) |
I680N |
probably damaging |
Het |
| Zfhx4 |
T |
C |
3: 5,467,795 (GRCm39) |
L2651P |
probably damaging |
Het |
| Zfp692 |
C |
T |
11: 58,199,881 (GRCm39) |
Q157* |
probably null |
Het |
| Zfp964 |
T |
A |
8: 70,116,587 (GRCm39) |
C396S |
unknown |
Het |
|
| Other mutations in Parp14 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Parp14
|
APN |
16 |
35,661,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00497:Parp14
|
APN |
16 |
35,655,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00754:Parp14
|
APN |
16 |
35,659,741 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL00960:Parp14
|
APN |
16 |
35,661,589 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01321:Parp14
|
APN |
16 |
35,676,929 (GRCm39) |
missense |
probably benign |
|
|
IGL01397:Parp14
|
APN |
16 |
35,679,098 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01591:Parp14
|
APN |
16 |
35,678,877 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL01728:Parp14
|
APN |
16 |
35,677,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01734:Parp14
|
APN |
16 |
35,678,970 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02156:Parp14
|
APN |
16 |
35,678,967 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02951:Parp14
|
APN |
16 |
35,678,903 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03067:Parp14
|
APN |
16 |
35,676,878 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03135:Parp14
|
APN |
16 |
35,678,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03141:Parp14
|
APN |
16 |
35,659,663 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03146:Parp14
|
APN |
16 |
35,678,823 (GRCm39) |
nonsense |
probably null |
|
|
IGL03333:Parp14
|
APN |
16 |
35,661,800 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL03391:Parp14
|
APN |
16 |
35,678,640 (GRCm39) |
missense |
probably benign |
|
|
thurston
|
UTSW |
16 |
35,664,785 (GRCm39) |
splice site |
probably benign |
|
|
PIT4585001:Parp14
|
UTSW |
16 |
35,678,975 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0306:Parp14
|
UTSW |
16 |
35,676,944 (GRCm39) |
missense |
probably benign |
|
|
R0586:Parp14
|
UTSW |
16 |
35,661,382 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0606:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0612:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0699:Parp14
|
UTSW |
16 |
35,680,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0786:Parp14
|
UTSW |
16 |
35,661,172 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0883:Parp14
|
UTSW |
16 |
35,678,888 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0900:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1087:Parp14
|
UTSW |
16 |
35,678,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1104:Parp14
|
UTSW |
16 |
35,664,785 (GRCm39) |
splice site |
probably benign |
|
|
R1120:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1134:Parp14
|
UTSW |
16 |
35,655,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1153:Parp14
|
UTSW |
16 |
35,678,041 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1159:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1160:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1237:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1238:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1239:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1423:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1511:Parp14
|
UTSW |
16 |
35,677,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1518:Parp14
|
UTSW |
16 |
35,677,008 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1619:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1707:Parp14
|
UTSW |
16 |
35,678,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1792:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1831:Parp14
|
UTSW |
16 |
35,678,958 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1840:Parp14
|
UTSW |
16 |
35,683,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1902:Parp14
|
UTSW |
16 |
35,673,888 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1943:Parp14
|
UTSW |
16 |
35,656,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1954:Parp14
|
UTSW |
16 |
35,678,671 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2115:Parp14
|
UTSW |
16 |
35,678,904 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2216:Parp14
|
UTSW |
16 |
35,677,575 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2519:Parp14
|
UTSW |
16 |
35,678,573 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3851:Parp14
|
UTSW |
16 |
35,674,118 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4052:Parp14
|
UTSW |
16 |
35,678,771 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4671:Parp14
|
UTSW |
16 |
35,678,691 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4867:Parp14
|
UTSW |
16 |
35,677,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4941:Parp14
|
UTSW |
16 |
35,666,403 (GRCm39) |
missense |
probably benign |
|
|
R4992:Parp14
|
UTSW |
16 |
35,661,512 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5055:Parp14
|
UTSW |
16 |
35,664,733 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5073:Parp14
|
UTSW |
16 |
35,655,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5170:Parp14
|
UTSW |
16 |
35,677,649 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5422:Parp14
|
UTSW |
16 |
35,686,545 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5543:Parp14
|
UTSW |
16 |
35,655,137 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5549:Parp14
|
UTSW |
16 |
35,661,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5553:Parp14
|
UTSW |
16 |
35,677,306 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5691:Parp14
|
UTSW |
16 |
35,683,909 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5774:Parp14
|
UTSW |
16 |
35,678,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5855:Parp14
|
UTSW |
16 |
35,661,297 (GRCm39) |
nonsense |
probably null |
|
|
R5942:Parp14
|
UTSW |
16 |
35,659,737 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5990:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5991:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6018:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6022:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6075:Parp14
|
UTSW |
16 |
35,677,389 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6395:Parp14
|
UTSW |
16 |
35,676,918 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6525:Parp14
|
UTSW |
16 |
35,680,811 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6683:Parp14
|
UTSW |
16 |
35,655,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7525:Parp14
|
UTSW |
16 |
35,677,861 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8011:Parp14
|
UTSW |
16 |
35,677,004 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8192:Parp14
|
UTSW |
16 |
35,691,584 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8367:Parp14
|
UTSW |
16 |
35,678,124 (GRCm39) |
missense |
probably benign |
0.36 |
|
R8526:Parp14
|
UTSW |
16 |
35,661,307 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8751:Parp14
|
UTSW |
16 |
35,677,181 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8962:Parp14
|
UTSW |
16 |
35,677,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Parp14
|
UTSW |
16 |
35,661,583 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9363:Parp14
|
UTSW |
16 |
35,678,586 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9366:Parp14
|
UTSW |
16 |
35,659,630 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9379:Parp14
|
UTSW |
16 |
35,680,853 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9562:Parp14
|
UTSW |
16 |
35,677,775 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9565:Parp14
|
UTSW |
16 |
35,677,775 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9696:Parp14
|
UTSW |
16 |
35,661,252 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9696:Parp14
|
UTSW |
16 |
35,661,251 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
X0026:Parp14
|
UTSW |
16 |
35,677,527 (GRCm39) |
nonsense |
probably null |
|
|
X0060:Parp14
|
UTSW |
16 |
35,655,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1088:Parp14
|
UTSW |
16 |
35,661,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Parp14
|
UTSW |
16 |
35,665,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Parp14
|
UTSW |
16 |
35,691,573 (GRCm39) |
missense |
probably benign |
0.16 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGTCATTGGTGTAGGAAAGCTGCTC -3'
(R):5'- TGAAGGAAATGCTCAACAGGACCC -3'
Sequencing Primer
(F):5'- TGGTAATCAGTTCCTTTAGCCAG -3'
(R):5'- CAAAAGCGATAATAGATGCCATTG -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation