Incidental Mutation 'R2433:Krtap16-3'
ID476378
Institutional Source Beutler Lab
Gene Symbol Krtap16-3
Ensembl Gene ENSMUSG00000096534
Gene Namekeratin associated protein 16-3
Synonyms
MMRRC Submission 040394-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.247) question?
Stock #R2433 (G1)
Quality Score225
Status Not validated
Chromosome16
Chromosomal Location88962273-88962873 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 88962645 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Cysteine at position 60 (Y60C)
Ref Sequence ENSEMBL: ENSMUSP00000139557 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000179707]
Predicted Effect unknown
Transcript: ENSMUST00000179707
AA Change: Y60C
SMART Domains Protein: ENSMUSP00000139557
Gene: ENSMUSG00000096534
AA Change: Y60C

DomainStartEndE-ValueType
Pfam:KRTAP 1 54 1.6e-15 PFAM
Pfam:KRTAP 48 80 4.2e-9 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000202919
AA Change: Y51C
Coding Region Coverage
  • 1x: 99.1%
  • 3x: 98.5%
  • 10x: 97.1%
  • 20x: 94.3%
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Atp6v0a4 A G 6: 38,082,029 probably null Het
Bpifb4 A G 2: 153,959,677 K573E probably damaging Het
Capn10 T A 1: 92,942,525 D244E probably benign Het
Dhrs11 C A 11: 84,828,919 probably benign Het
Eipr1 G A 12: 28,863,043 G248R probably damaging Het
Fam120a A C 13: 48,933,968 D305E probably damaging Het
Hmgcr A G 13: 96,665,885 L97P probably damaging Het
Htt A T 5: 34,907,541 S3033C possibly damaging Het
Igkv10-94 T C 6: 68,704,575 T94A probably benign Het
Lrp4 G A 2: 91,506,015 V1724I probably benign Het
Myo5b A G 18: 74,759,087 Y1634C probably damaging Het
Nrxn3 A G 12: 89,976,392 Y96C probably damaging Het
Obscn A T 11: 59,039,086 probably null Het
Pde3b T C 7: 114,526,837 C769R probably benign Het
Phlpp2 T G 8: 109,940,002 C1054W probably damaging Het
Pttg1 A T 11: 43,420,351 V193D probably damaging Het
Robo1 T C 16: 72,970,239 L433S probably benign Het
Sema4f A T 6: 82,939,509 C13S possibly damaging Het
Slc12a3 T C 8: 94,346,316 L689P probably benign Het
Slc7a6os T C 8: 106,204,371 N211S possibly damaging Het
Smurf2 T A 11: 106,868,664 I69F probably benign Het
St8sia3 A T 18: 64,269,716 H198L probably benign Het
Tacc3 A G 5: 33,671,739 K594R possibly damaging Het
Trip12 A T 1: 84,743,823 I1396K possibly damaging Het
Ugcg A G 4: 59,207,876 T72A possibly damaging Het
Zfp944 A T 17: 22,339,212 Y351* probably null Het
Other mutations in Krtap16-3
AlleleSourceChrCoordTypePredicted EffectPPH Score
R6670:Krtap16-3 UTSW 16 88962652 missense unknown
R7098:Krtap16-3 UTSW 16 88962672 missense unknown
Predicted Primers
Posted On2017-05-11