Incidental Mutation 'R6029:Qars1'
| ID |
480274 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Qars1
|
| Ensembl Gene |
ENSMUSG00000032604 |
| Gene Name |
glutaminyl-tRNA synthetase 1 |
| Synonyms |
1200016L19Rik, Qars, 1110018N24Rik |
| MMRRC Submission |
044201-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.964)
|
| Stock # |
R6029 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
108385204-108393140 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 108390889 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Phenylalanine
at position 470
(L470F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000006838
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000006838]
[ENSMUST00000006851]
[ENSMUST00000112155]
[ENSMUST00000134939]
[ENSMUST00000193258]
[ENSMUST00000192819]
[ENSMUST00000192932]
[ENSMUST00000208214]
[ENSMUST00000208177]
[ENSMUST00000207862]
[ENSMUST00000208581]
[ENSMUST00000207790]
[ENSMUST00000207810]
[ENSMUST00000208162]
[ENSMUST00000207947]
[ENSMUST00000195513]
[ENSMUST00000194045]
[ENSMUST00000193348]
[ENSMUST00000194385]
[ENSMUST00000195563]
|
| AlphaFold |
Q8BML9 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000006838
AA Change: L470F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000006838
Gene: ENSMUSG00000032604
AA Change: L470F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:tRNA_synt_1c_R1
|
4 |
162 |
1.2e-54 |
PFAM |
|
Pfam:tRNA_synt_1c_R2
|
165 |
256 |
6.5e-31 |
PFAM |
|
Pfam:tRNA-synt_1c
|
263 |
563 |
4.5e-119 |
PFAM |
|
Pfam:tRNA-synt_1c_C
|
565 |
752 |
6.9e-48 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000006851
|
| SMART Domains |
Protein: ENSMUSP00000006851
Gene: ENSMUSG00000006673
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
79 |
123 |
N/A |
INTRINSIC |
|
low complexity region
|
128 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
419 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
478 |
N/A |
INTRINSIC |
|
Pfam:DUF3504
|
597 |
761 |
1.8e-65 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112155
|
| SMART Domains |
Protein: ENSMUSP00000107782
Gene: ENSMUSG00000006673
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
79 |
123 |
N/A |
INTRINSIC |
|
low complexity region
|
128 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
419 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
478 |
N/A |
INTRINSIC |
|
Pfam:DUF3504
|
600 |
760 |
2.3e-64 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000131005
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000134939
AA Change: L446F
|
| SMART Domains |
Protein: ENSMUSP00000122918
Gene: ENSMUSG00000032604
AA Change: L446F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:tRNA_synt_1c_R1
|
1 |
163 |
1.1e-55 |
PFAM |
|
Pfam:tRNA_synt_1c_R2
|
164 |
256 |
6.9e-31 |
PFAM |
|
Pfam:tRNA-synt_1c
|
263 |
563 |
2.5e-115 |
PFAM |
|
Pfam:tRNA-synt_1c_C
|
565 |
720 |
5.7e-35 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000136293
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000137655
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000141903
AA Change: L67F
|
| SMART Domains |
Protein: ENSMUSP00000121146
Gene: ENSMUSG00000032604
AA Change: L67F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:tRNA-synt_1c
|
2 |
148 |
2.1e-50 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141201
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192331
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192065
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000144253
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192627
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192659
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154311
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154324
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141780
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000137980
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193258
|
| SMART Domains |
Protein: ENSMUSP00000141267
Gene: ENSMUSG00000006673
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1dgna_
|
7 |
48 |
9e-3 |
SMART |
|
low complexity region
|
79 |
123 |
N/A |
INTRINSIC |
|
low complexity region
|
128 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
419 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
478 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192819
|
| SMART Domains |
Protein: ENSMUSP00000142027
Gene: ENSMUSG00000006673
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1dgna_
|
7 |
48 |
1e-3 |
SMART |
|
low complexity region
|
85 |
95 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192932
|
| SMART Domains |
Protein: ENSMUSP00000141215
Gene: ENSMUSG00000006673
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1dgna_
|
7 |
48 |
3e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208214
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208177
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208506
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000207126
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207862
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000207062
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208581
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208962
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207734
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207790
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208074
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207810
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000208102
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194743
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208162
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207947
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207180
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207713
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000208069
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195513
|
| SMART Domains |
Protein: ENSMUSP00000142025
Gene: ENSMUSG00000006673
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1dgna_
|
7 |
48 |
3e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194045
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193348
|
| SMART Domains |
Protein: ENSMUSP00000141691
Gene: ENSMUSG00000006673
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1dgna_
|
7 |
48 |
1e-3 |
SMART |
|
low complexity region
|
80 |
96 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194385
|
| SMART Domains |
Protein: ENSMUSP00000142211
Gene: ENSMUSG00000006673
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1cy5a_
|
9 |
45 |
8e-3 |
SMART |
|
low complexity region
|
79 |
134 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195563
|
| SMART Domains |
Protein: ENSMUSP00000141716
Gene: ENSMUSG00000006673
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1dgna_
|
7 |
48 |
9e-3 |
SMART |
|
low complexity region
|
79 |
123 |
N/A |
INTRINSIC |
|
low complexity region
|
128 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
192 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.5%
- 10x: 97.7%
- 20x: 92.7%
|
| Validation Efficiency |
97% (87/90) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
G |
A |
2: 68,524,370 (GRCm39) |
|
probably null |
Het |
| Adi1 |
G |
A |
12: 28,729,318 (GRCm39) |
|
probably benign |
Het |
| Afg3l2 |
G |
T |
18: 67,554,329 (GRCm39) |
L458M |
probably damaging |
Het |
| Apob |
A |
G |
12: 8,066,243 (GRCm39) |
E4371G |
probably damaging |
Het |
| Ash1l |
T |
C |
3: 88,892,326 (GRCm39) |
Y1402H |
probably damaging |
Het |
| Aspm |
T |
G |
1: 139,408,728 (GRCm39) |
C2538W |
possibly damaging |
Het |
| Brd10 |
A |
G |
19: 29,732,367 (GRCm39) |
|
probably benign |
Het |
| Btbd16 |
T |
C |
7: 130,420,802 (GRCm39) |
V353A |
probably benign |
Het |
| Cad |
C |
T |
5: 31,212,327 (GRCm39) |
S10L |
possibly damaging |
Het |
| Cdc42bpa |
T |
C |
1: 179,939,352 (GRCm39) |
S877P |
probably damaging |
Het |
| Cep152 |
A |
T |
2: 125,405,552 (GRCm39) |
V1660D |
probably benign |
Het |
| Clrn2 |
G |
T |
5: 45,617,528 (GRCm39) |
G133V |
probably damaging |
Het |
| Clstn2 |
T |
C |
9: 97,338,634 (GRCm39) |
I842V |
probably benign |
Het |
| Cpt1c |
C |
T |
7: 44,614,548 (GRCm39) |
A434T |
probably benign |
Het |
| D130052B06Rik |
G |
T |
11: 33,573,477 (GRCm39) |
V70L |
possibly damaging |
Het |
| Dlg1 |
T |
A |
16: 31,612,388 (GRCm39) |
V317E |
probably damaging |
Het |
| Dock10 |
T |
C |
1: 80,514,663 (GRCm39) |
E1084G |
possibly damaging |
Het |
| Dync2h1 |
A |
G |
9: 7,157,646 (GRCm39) |
V827A |
probably benign |
Het |
| E030030I06Rik |
A |
G |
10: 22,024,832 (GRCm39) |
L27P |
unknown |
Het |
| Ero1b |
T |
A |
13: 12,589,714 (GRCm39) |
L39Q |
probably damaging |
Het |
| Erp27 |
T |
C |
6: 136,888,609 (GRCm39) |
D123G |
probably damaging |
Het |
| Fasn |
G |
T |
11: 120,711,735 (GRCm39) |
F148L |
probably damaging |
Het |
| Fbxl5 |
T |
C |
5: 43,922,746 (GRCm39) |
E218G |
probably damaging |
Het |
| Fbxw28 |
A |
T |
9: 109,158,493 (GRCm39) |
D210E |
probably damaging |
Het |
| Gm10653 |
T |
A |
9: 62,748,796 (GRCm39) |
|
probably benign |
Het |
| Gm17067 |
A |
G |
7: 42,357,554 (GRCm39) |
L316S |
probably benign |
Het |
| Gm29106 |
T |
C |
1: 118,127,990 (GRCm39) |
S561P |
probably damaging |
Het |
| Hmcn1 |
C |
A |
1: 150,508,188 (GRCm39) |
K3699N |
probably benign |
Het |
| Itch |
T |
A |
2: 155,021,009 (GRCm39) |
|
probably null |
Het |
| Itpr3 |
C |
T |
17: 27,317,145 (GRCm39) |
A800V |
probably damaging |
Het |
| Kdm2b |
A |
T |
5: 123,017,650 (GRCm39) |
M1052K |
probably damaging |
Het |
| Kdm4b |
T |
C |
17: 56,703,576 (GRCm39) |
M712T |
probably damaging |
Het |
| Kmt5b |
A |
G |
19: 3,852,104 (GRCm39) |
E137G |
probably damaging |
Het |
| Krt33a |
G |
A |
11: 99,903,289 (GRCm39) |
T251I |
probably benign |
Het |
| Lrrc4b |
G |
T |
7: 44,111,754 (GRCm39) |
R542L |
probably benign |
Het |
| Macf1 |
C |
A |
4: 123,401,126 (GRCm39) |
S653I |
probably damaging |
Het |
| Macrod2 |
G |
A |
2: 142,160,367 (GRCm39) |
V408M |
probably damaging |
Het |
| Macroh2a2 |
T |
C |
10: 61,583,541 (GRCm39) |
T200A |
possibly damaging |
Het |
| Mapkapk3 |
G |
T |
9: 107,166,425 (GRCm39) |
A40E |
possibly damaging |
Het |
| Mmp20 |
G |
A |
9: 7,639,302 (GRCm39) |
V157I |
probably benign |
Het |
| Mrps28 |
T |
C |
3: 8,988,805 (GRCm39) |
R18G |
possibly damaging |
Het |
| Msrb2 |
T |
A |
2: 19,399,122 (GRCm39) |
C162S |
probably damaging |
Het |
| Naa80 |
A |
G |
9: 107,460,753 (GRCm39) |
Y216C |
probably damaging |
Het |
| Nckap5 |
T |
G |
1: 125,953,523 (GRCm39) |
T1078P |
possibly damaging |
Het |
| Nectin3 |
T |
C |
16: 46,256,763 (GRCm39) |
Y91C |
probably benign |
Het |
| Nf2 |
G |
T |
11: 4,734,566 (GRCm39) |
|
probably null |
Het |
| Or10d1b |
G |
A |
9: 39,613,696 (GRCm39) |
A123V |
probably damaging |
Het |
| Or13a23-ps1 |
A |
T |
7: 140,118,789 (GRCm39) |
M120L |
unknown |
Het |
| Or1e16 |
AGCGGTCGTAGGC |
AGC |
11: 73,286,480 (GRCm39) |
|
probably null |
Het |
| Or2y10 |
A |
T |
11: 49,455,428 (GRCm39) |
I227F |
possibly damaging |
Het |
| Or4c29 |
T |
C |
2: 88,740,380 (GRCm39) |
D119G |
probably damaging |
Het |
| Or4g7 |
T |
A |
2: 111,309,310 (GRCm39) |
Y60* |
probably null |
Het |
| Or8b36 |
ATTGCTGTTT |
ATTGCTGTTTGCTGTTT |
9: 37,937,836 (GRCm39) |
|
probably null |
Het |
| Oxr1 |
T |
G |
15: 41,689,297 (GRCm39) |
L507W |
probably damaging |
Het |
| Plxna2 |
A |
T |
1: 194,481,883 (GRCm39) |
K1451M |
probably damaging |
Het |
| Plxna2 |
A |
G |
1: 194,476,735 (GRCm39) |
M1184V |
probably benign |
Het |
| Pofut1 |
G |
A |
2: 153,101,713 (GRCm39) |
|
probably null |
Het |
| Ppp1r16b |
T |
C |
2: 158,597,137 (GRCm39) |
V257A |
possibly damaging |
Het |
| Prss56 |
G |
A |
1: 87,115,279 (GRCm39) |
W498* |
probably null |
Het |
| Ptpru |
A |
G |
4: 131,498,604 (GRCm39) |
F1329S |
probably damaging |
Het |
| Pusl1 |
A |
G |
4: 155,973,920 (GRCm39) |
F278S |
probably damaging |
Het |
| Rbm8a2 |
T |
C |
1: 175,806,312 (GRCm39) |
D55G |
probably benign |
Het |
| Rora |
T |
A |
9: 69,271,734 (GRCm39) |
N181K |
probably benign |
Het |
| Rufy3 |
A |
G |
5: 88,775,114 (GRCm39) |
D262G |
probably damaging |
Het |
| Sh3gl2 |
G |
A |
4: 85,299,651 (GRCm39) |
V212M |
probably damaging |
Het |
| Sis |
G |
A |
3: 72,835,641 (GRCm39) |
T907I |
probably benign |
Het |
| Slc38a3 |
A |
T |
9: 107,529,374 (GRCm39) |
I456N |
probably damaging |
Het |
| Slc4a8 |
T |
A |
15: 100,705,220 (GRCm39) |
C809S |
probably benign |
Het |
| Snap91 |
A |
T |
9: 86,707,133 (GRCm39) |
|
probably null |
Het |
| Spaca6 |
A |
G |
17: 18,051,458 (GRCm39) |
T45A |
probably benign |
Het |
| Speer1m |
A |
T |
5: 11,970,680 (GRCm39) |
L84F |
probably damaging |
Het |
| Spry1 |
T |
C |
3: 37,696,997 (GRCm39) |
I80T |
possibly damaging |
Het |
| St8sia2 |
A |
G |
7: 73,610,458 (GRCm39) |
L275P |
possibly damaging |
Het |
| Supt7l |
C |
A |
5: 31,684,331 (GRCm39) |
|
probably null |
Het |
| Tdo2 |
T |
A |
3: 81,868,747 (GRCm39) |
K304N |
probably damaging |
Het |
| Tdrd12 |
A |
T |
7: 35,184,655 (GRCm39) |
Y753N |
probably damaging |
Het |
| Topbp1 |
A |
T |
9: 103,222,152 (GRCm39) |
Q1341L |
probably benign |
Het |
| Trim14 |
G |
T |
4: 46,506,998 (GRCm39) |
A406E |
probably benign |
Het |
| Trp63 |
C |
T |
16: 25,686,964 (GRCm39) |
R393W |
probably damaging |
Het |
| Trrap |
T |
C |
5: 144,754,489 (GRCm39) |
V1932A |
possibly damaging |
Het |
| Trrap |
T |
C |
5: 144,762,724 (GRCm39) |
M2399T |
possibly damaging |
Het |
| Unc45b |
A |
G |
11: 82,804,153 (GRCm39) |
N110S |
probably damaging |
Het |
| Usp32 |
G |
T |
11: 84,916,408 (GRCm39) |
H845Q |
probably damaging |
Het |
| Usp44 |
G |
A |
10: 93,682,494 (GRCm39) |
D268N |
probably damaging |
Het |
| Vmn1r18 |
T |
G |
6: 57,367,451 (GRCm39) |
R34S |
possibly damaging |
Het |
| Vmn2r103 |
T |
A |
17: 20,014,478 (GRCm39) |
Y423* |
probably null |
Het |
| Wapl |
A |
T |
14: 34,461,204 (GRCm39) |
E1054V |
possibly damaging |
Het |
| Zbtb8b |
A |
G |
4: 129,322,286 (GRCm39) |
Y392H |
probably damaging |
Het |
| Zdhhc2 |
A |
T |
8: 40,925,968 (GRCm39) |
Q321L |
probably null |
Het |
| Zfp983 |
A |
G |
17: 21,881,401 (GRCm39) |
D443G |
probably benign |
Het |
|
| Other mutations in Qars1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01570:Qars1
|
APN |
9 |
108,388,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02336:Qars1
|
APN |
9 |
108,392,185 (GRCm39) |
nonsense |
probably null |
|
|
IGL02393:Qars1
|
APN |
9 |
108,391,528 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03102:Qars1
|
APN |
9 |
108,386,118 (GRCm39) |
missense |
probably benign |
0.35 |
|
R0576:Qars1
|
UTSW |
9 |
108,392,161 (GRCm39) |
intron |
probably benign |
|
|
R1777:Qars1
|
UTSW |
9 |
108,385,400 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1824:Qars1
|
UTSW |
9 |
108,391,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1871:Qars1
|
UTSW |
9 |
108,391,315 (GRCm39) |
splice site |
probably null |
|
|
R1897:Qars1
|
UTSW |
9 |
108,391,282 (GRCm39) |
nonsense |
probably null |
|
|
R1952:Qars1
|
UTSW |
9 |
108,390,380 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1981:Qars1
|
UTSW |
9 |
108,392,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2172:Qars1
|
UTSW |
9 |
108,386,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2698:Qars1
|
UTSW |
9 |
108,385,642 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4381:Qars1
|
UTSW |
9 |
108,387,382 (GRCm39) |
unclassified |
probably benign |
|
|
R4608:Qars1
|
UTSW |
9 |
108,386,625 (GRCm39) |
splice site |
probably null |
|
|
R4677:Qars1
|
UTSW |
9 |
108,386,889 (GRCm39) |
unclassified |
probably benign |
|
|
R4974:Qars1
|
UTSW |
9 |
108,386,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5234:Qars1
|
UTSW |
9 |
108,391,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5548:Qars1
|
UTSW |
9 |
108,390,117 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5817:Qars1
|
UTSW |
9 |
108,387,441 (GRCm39) |
unclassified |
probably benign |
|
|
R6110:Qars1
|
UTSW |
9 |
108,385,297 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6889:Qars1
|
UTSW |
9 |
108,390,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7034:Qars1
|
UTSW |
9 |
108,391,976 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7036:Qars1
|
UTSW |
9 |
108,391,976 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7136:Qars1
|
UTSW |
9 |
108,389,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7178:Qars1
|
UTSW |
9 |
108,392,322 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7192:Qars1
|
UTSW |
9 |
108,388,760 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7235:Qars1
|
UTSW |
9 |
108,387,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7813:Qars1
|
UTSW |
9 |
108,386,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8248:Qars1
|
UTSW |
9 |
108,386,651 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8558:Qars1
|
UTSW |
9 |
108,392,422 (GRCm39) |
missense |
probably benign |
|
|
R9126:Qars1
|
UTSW |
9 |
108,386,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9245:Qars1
|
UTSW |
9 |
108,386,132 (GRCm39) |
nonsense |
probably null |
|
|
R9632:Qars1
|
UTSW |
9 |
108,391,582 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTACCAAGGAGTTCCAGGC -3'
(R):5'- CCCTTTGGATAAGAGGGTGGTC -3'
Sequencing Primer
(F):5'- CAACTTGTGGAAGTCAGCTTTC -3'
(R):5'- TGGTCAGAAGATCTTAAACAGCAC -3'
|
| Posted On |
2017-06-26 |
Incidental Mutation