Mutagenetix > Incidental Mutation

Incidental Mutation 'R6000:Ankrd11'

480785

Institutional Source

Beutler Lab

Gene Symbol

Ankrd11

Ensembl Gene

ENSMUSG00000035569

Gene Name

ankyrin repeat domain 11

Synonyms

Yod, 3010027A04Rik, 2410104C19Rik, 9530048I21Rik

MMRRC Submission

044179-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R6000 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

123610561-123769016 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 123617934 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 1973 (S1973P)

Ref Sequence

ENSEMBL: ENSMUSP00000095938 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000098333] [ENSMUST00000098334] [ENSMUST00000127664] [ENSMUST00000172906]

AlphaFold

E9Q4F7

Predicted Effect

possibly damaging
Transcript: ENSMUST00000098333
AA Change: S1973P

PolyPhen 2 Score 0.727 (Sensitivity: 0.86; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000095938
Gene: ENSMUSG00000035569
AA Change: S1973P

Domain	Start	End	E-Value	Type
ANK	188	217	2.58e-3	SMART
ANK	221	250	1.31e-4	SMART
ANK	254	283	5.04e-6	SMART
low complexity region	311	324	N/A	INTRINSIC
low complexity region	366	377	N/A	INTRINSIC
low complexity region	429	440	N/A	INTRINSIC
low complexity region	470	487	N/A	INTRINSIC
low complexity region	499	521	N/A	INTRINSIC
low complexity region	534	549	N/A	INTRINSIC
low complexity region	596	609	N/A	INTRINSIC
low complexity region	649	669	N/A	INTRINSIC
coiled coil region	786	826	N/A	INTRINSIC
low complexity region	867	877	N/A	INTRINSIC
low complexity region	965	984	N/A	INTRINSIC
low complexity region	1040	1055	N/A	INTRINSIC
low complexity region	1058	1082	N/A	INTRINSIC
low complexity region	1187	1200	N/A	INTRINSIC
low complexity region	1204	1227	N/A	INTRINSIC
low complexity region	1268	1289	N/A	INTRINSIC
low complexity region	1294	1306	N/A	INTRINSIC
coiled coil region	1374	1406	N/A	INTRINSIC
low complexity region	1476	1496	N/A	INTRINSIC
low complexity region	1508	1523	N/A	INTRINSIC
low complexity region	1526	1547	N/A	INTRINSIC
coiled coil region	1598	1625	N/A	INTRINSIC
low complexity region	1770	1781	N/A	INTRINSIC
low complexity region	1874	1885	N/A	INTRINSIC
low complexity region	1913	1922	N/A	INTRINSIC
low complexity region	1969	1979	N/A	INTRINSIC
low complexity region	2035	2045	N/A	INTRINSIC
low complexity region	2057	2071	N/A	INTRINSIC
low complexity region	2162	2179	N/A	INTRINSIC
low complexity region	2191	2209	N/A	INTRINSIC
low complexity region	2224	2236	N/A	INTRINSIC
low complexity region	2250	2263	N/A	INTRINSIC
low complexity region	2294	2305	N/A	INTRINSIC
low complexity region	2391	2409	N/A	INTRINSIC
low complexity region	2445	2455	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000098334
AA Change: S1952P

PolyPhen 2 Score 0.373 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000095939
Gene: ENSMUSG00000035569
AA Change: S1952P

Domain	Start	End	E-Value	Type
ANK	167	196	2.58e-3	SMART
ANK	200	229	1.31e-4	SMART
ANK	233	262	5.04e-6	SMART
low complexity region	290	303	N/A	INTRINSIC
low complexity region	345	356	N/A	INTRINSIC
low complexity region	408	419	N/A	INTRINSIC
low complexity region	449	466	N/A	INTRINSIC
low complexity region	478	500	N/A	INTRINSIC
low complexity region	513	528	N/A	INTRINSIC
low complexity region	575	588	N/A	INTRINSIC
low complexity region	628	648	N/A	INTRINSIC
coiled coil region	765	805	N/A	INTRINSIC
low complexity region	846	856	N/A	INTRINSIC
low complexity region	944	963	N/A	INTRINSIC
low complexity region	1019	1034	N/A	INTRINSIC
low complexity region	1037	1061	N/A	INTRINSIC
low complexity region	1166	1179	N/A	INTRINSIC
low complexity region	1183	1206	N/A	INTRINSIC
low complexity region	1247	1268	N/A	INTRINSIC
low complexity region	1273	1285	N/A	INTRINSIC
coiled coil region	1353	1385	N/A	INTRINSIC
low complexity region	1455	1475	N/A	INTRINSIC
low complexity region	1487	1502	N/A	INTRINSIC
low complexity region	1505	1526	N/A	INTRINSIC
coiled coil region	1577	1604	N/A	INTRINSIC
low complexity region	1749	1760	N/A	INTRINSIC
low complexity region	1853	1864	N/A	INTRINSIC
low complexity region	1892	1901	N/A	INTRINSIC
low complexity region	1948	1958	N/A	INTRINSIC
low complexity region	2014	2024	N/A	INTRINSIC
low complexity region	2036	2050	N/A	INTRINSIC
low complexity region	2141	2158	N/A	INTRINSIC
low complexity region	2170	2188	N/A	INTRINSIC
low complexity region	2203	2215	N/A	INTRINSIC
low complexity region	2229	2242	N/A	INTRINSIC
low complexity region	2273	2284	N/A	INTRINSIC
low complexity region	2370	2388	N/A	INTRINSIC
low complexity region	2424	2434	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000127664

SMART Domains

Protein: ENSMUSP00000118564
Gene: ENSMUSG00000092329

Domain	Start	End	E-Value	Type
Pfam:Glycos_transf_2	104	287	7.4e-31	PFAM
Pfam:Glyco_transf_7C	261	331	4.9e-8	PFAM
RICIN	406	531	9.28e-27	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000172906

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000211940

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000212337

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000212728

Coding Region Coverage

1x: 99.9%
3x: 99.5%
10x: 97.4%
20x: 91.7%

Validation Efficiency

100% (64/64)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012]
PHENOTYPE: Mice homozygous for a spontaneous allele die by E9.5, are small and fail to turn. Mice heterozygous for a spontaneous allele exhibit craniofacial abnormalities, decreased weight, osteoporosis and osteopenia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 66 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310034C09Rik	T	C	16: 88,556,427 (GRCm39)	C214R	possibly damaging	Het
Ahnak	A	T	19: 8,990,475 (GRCm39)	K3920*	probably null	Het
Alox12b	A	G	11: 69,060,394 (GRCm39)	D650G	probably damaging	Het
Amt	A	T	9: 108,178,684 (GRCm39)	Y400F	probably benign	Het
Aoc1	A	T	6: 48,884,573 (GRCm39)	T539S	probably benign	Het
Arhgap44	CTGCT	CTGCTTGCT	11: 64,922,910 (GRCm39)		probably null	Het
Ccdc15	C	T	9: 37,227,060 (GRCm39)	G292S	probably benign	Het
Ccdc162	C	T	10: 41,437,159 (GRCm39)	C287Y	possibly damaging	Het
Ccn6	T	C	10: 39,034,296 (GRCm39)	Y102C	probably damaging	Het
Cdk15	G	A	1: 59,328,818 (GRCm39)	G244D	probably damaging	Het
Cep290	T	A	10: 100,377,649 (GRCm39)	Y1560N	probably damaging	Het
Cfap251	A	G	5: 123,392,435 (GRCm39)		probably benign	Het
Cic	A	C	7: 24,971,423 (GRCm39)	I385L	probably benign	Het
Cobl	A	T	11: 12,319,684 (GRCm39)	F231L	probably benign	Het
Cpeb1	T	C	7: 81,011,428 (GRCm39)	D171G	possibly damaging	Het
Csnk1g2	T	A	10: 80,474,778 (GRCm39)	V305E	probably damaging	Het
Cyp2c29	A	G	19: 39,296,050 (GRCm39)		probably null	Het
Dner	A	T	1: 84,361,650 (GRCm39)	M653K	possibly damaging	Het
Dst	T	A	1: 34,251,304 (GRCm39)	M4311K	possibly damaging	Het
Ep400	A	G	5: 110,831,067 (GRCm39)	S2200P	unknown	Het
Ephb2	A	T	4: 136,411,341 (GRCm39)	S440T	possibly damaging	Het
Ercc1	A	T	7: 19,081,086 (GRCm39)		probably benign	Het
Folh1	T	A	7: 86,375,142 (GRCm39)	N615Y	probably benign	Het
Gm7298	T	C	6: 121,742,038 (GRCm39)	Y487H	possibly damaging	Het
Gucy1b2	A	T	14: 62,656,499 (GRCm39)	I286N	probably benign	Het
Hr	A	G	14: 70,805,273 (GRCm39)	D1005G	probably damaging	Het
Ifrd1	C	A	12: 40,266,243 (GRCm39)	V117F	possibly damaging	Het
Ift140	A	T	17: 25,255,934 (GRCm39)	T210S	probably benign	Het
Igll1	C	A	16: 16,681,805 (GRCm39)		probably benign	Het
Ino80	G	T	2: 119,204,989 (GRCm39)	S1512R	probably benign	Het
Intu	A	T	3: 40,608,578 (GRCm39)	K197*	probably null	Het
Kdm6b	A	G	11: 69,294,424 (GRCm39)	L1216P	unknown	Het
Klrb1c	T	G	6: 128,761,120 (GRCm39)	D169A	probably damaging	Het
Lamp3	T	A	16: 19,519,698 (GRCm39)	T162S	possibly damaging	Het
Mapk10	G	A	5: 103,114,342 (GRCm39)	P319S	probably damaging	Het
Mapk10	G	A	5: 103,114,341 (GRCm39)	P319L	probably damaging	Het
Mical3	T	C	6: 120,998,281 (GRCm39)	T702A	probably benign	Het
Mstn	C	T	1: 53,100,828 (GRCm39)		probably benign	Het
Nckap1l	T	C	15: 103,387,242 (GRCm39)	S706P	probably benign	Het
Nckap5l	G	A	15: 99,324,766 (GRCm39)	T579I	probably damaging	Het
Or13p3	A	T	4: 118,567,441 (GRCm39)	N279I	probably damaging	Het
Or4a27	C	A	2: 88,559,575 (GRCm39)	A123S	probably damaging	Het
Or8s16	G	A	15: 98,211,317 (GRCm39)	T38I	probably benign	Het
Pcdh18	A	C	3: 49,708,913 (GRCm39)	S801A	probably damaging	Het
Pde11a	A	T	2: 75,848,204 (GRCm39)	D874E	probably damaging	Het
Pfdn6	G	T	17: 34,158,589 (GRCm39)	P62T	probably damaging	Het
Pkd1l1	A	G	11: 8,900,427 (GRCm39)	I38T	probably benign	Het
Prkdc	A	T	16: 15,647,561 (GRCm39)	I3662F	possibly damaging	Het
Psg26	A	T	7: 18,216,617 (GRCm39)	L74*	probably null	Het
Rassf6	A	G	5: 90,751,736 (GRCm39)	V341A	probably damaging	Het
Rsad2	C	A	12: 26,497,150 (GRCm39)		probably null	Het
Rwdd3	A	G	3: 120,950,162 (GRCm39)	Y95H	probably damaging	Het
Scfd1	A	G	12: 51,492,457 (GRCm39)	I589V	possibly damaging	Het
Sgsm1	A	T	5: 113,434,704 (GRCm39)	I131N	probably damaging	Het
Tecpr1	A	G	5: 144,148,239 (GRCm39)	S389P	probably benign	Het
Tle3	T	A	9: 61,281,296 (GRCm39)	I29N	probably damaging	Het
Tmem63c	C	A	12: 87,103,971 (GRCm39)	N73K	probably damaging	Het
Tpm2	T	A	4: 43,518,301 (GRCm39)		probably null	Het
Trak2	A	T	1: 58,950,971 (GRCm39)	D405E	possibly damaging	Het
Ttn	C	A	2: 76,575,516 (GRCm39)	A23380S	probably damaging	Het
Ttn	A	T	2: 76,715,495 (GRCm39)		probably benign	Het
Tub	T	C	7: 108,628,857 (GRCm39)	S391P	probably damaging	Het
Ush2a	G	T	1: 187,999,223 (GRCm39)	E178*	probably null	Het
Vamp9	G	T	5: 100,089,226 (GRCm39)	A164S	probably benign	Het
Ylpm1	C	A	12: 85,044,030 (GRCm39)	T256K	unknown	Het
Zfp1007	A	G	5: 109,824,730 (GRCm39)	V240A	probably benign	Het

Other mutations in Ankrd11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00949:Ankrd11	APN	8	123,635,467 (GRCm39)	missense	possibly damaging	0.59
IGL00971:Ankrd11	APN	8	123,622,092 (GRCm39)	missense	probably damaging	1.00
IGL01017:Ankrd11	APN	8	123,621,467 (GRCm39)	missense	probably damaging	1.00
IGL01137:Ankrd11	APN	8	123,611,075 (GRCm39)	missense	probably damaging	0.99
IGL01659:Ankrd11	APN	8	123,622,110 (GRCm39)	missense	probably damaging	1.00
IGL01920:Ankrd11	APN	8	123,642,636 (GRCm39)	splice site	probably benign
IGL01964:Ankrd11	APN	8	123,616,475 (GRCm39)	missense	probably damaging	0.97
IGL02131:Ankrd11	APN	8	123,621,149 (GRCm39)	missense	probably damaging	1.00
IGL02226:Ankrd11	APN	8	123,618,984 (GRCm39)	missense	probably damaging	1.00
IGL02549:Ankrd11	APN	8	123,618,032 (GRCm39)	missense	probably damaging	1.00
IGL02642:Ankrd11	APN	8	123,617,390 (GRCm39)	missense	probably damaging	1.00
IGL02643:Ankrd11	APN	8	123,619,061 (GRCm39)	missense	probably damaging	0.98
IGL02861:Ankrd11	APN	8	123,622,566 (GRCm39)	missense	probably damaging	0.99
IGL03086:Ankrd11	APN	8	123,621,249 (GRCm39)	missense	probably damaging	1.00
IGL03336:Ankrd11	APN	8	123,618,582 (GRCm39)	missense	probably benign	0.00
anchors	UTSW	8	123,622,509 (GRCm39)	missense	probably damaging	0.99
away	UTSW	8	123,618,692 (GRCm39)	missense	probably damaging	1.00
bluebell	UTSW	8	123,618,524 (GRCm39)	missense	probably damaging	0.97
Navy	UTSW	8	123,635,473 (GRCm39)	nonsense	probably null
BB001:Ankrd11	UTSW	8	123,622,641 (GRCm39)	missense	possibly damaging	0.95
BB011:Ankrd11	UTSW	8	123,622,641 (GRCm39)	missense	possibly damaging	0.95
R0051:Ankrd11	UTSW	8	123,616,481 (GRCm39)	missense	probably damaging	1.00
R0051:Ankrd11	UTSW	8	123,616,481 (GRCm39)	missense	probably damaging	1.00
R0110:Ankrd11	UTSW	8	123,618,914 (GRCm39)	missense	possibly damaging	0.95
R0281:Ankrd11	UTSW	8	123,622,307 (GRCm39)	missense	probably benign	0.01
R0450:Ankrd11	UTSW	8	123,618,914 (GRCm39)	missense	possibly damaging	0.95
R0481:Ankrd11	UTSW	8	123,626,775 (GRCm39)	missense	probably damaging	1.00
R0542:Ankrd11	UTSW	8	123,622,509 (GRCm39)	missense	probably damaging	0.99
R0606:Ankrd11	UTSW	8	123,619,571 (GRCm39)	missense	probably benign	0.04
R0702:Ankrd11	UTSW	8	123,616,505 (GRCm39)	missense	probably damaging	1.00
R0730:Ankrd11	UTSW	8	123,618,692 (GRCm39)	missense	probably damaging	1.00
R0737:Ankrd11	UTSW	8	123,622,575 (GRCm39)	missense	probably damaging	0.99
R1401:Ankrd11	UTSW	8	123,619,789 (GRCm39)	missense	probably benign	0.23
R1464:Ankrd11	UTSW	8	123,619,463 (GRCm39)	missense	probably damaging	1.00
R1464:Ankrd11	UTSW	8	123,619,463 (GRCm39)	missense	probably damaging	1.00
R1470:Ankrd11	UTSW	8	123,626,463 (GRCm39)	missense	probably damaging	0.98
R1470:Ankrd11	UTSW	8	123,626,463 (GRCm39)	missense	probably damaging	0.98
R1641:Ankrd11	UTSW	8	123,618,485 (GRCm39)	missense	probably benign	0.03
R1950:Ankrd11	UTSW	8	123,616,608 (GRCm39)	missense	probably damaging	1.00
R2004:Ankrd11	UTSW	8	123,629,161 (GRCm39)	critical splice donor site	probably null
R2401:Ankrd11	UTSW	8	123,635,473 (GRCm39)	nonsense	probably null
R2425:Ankrd11	UTSW	8	123,619,902 (GRCm39)	missense	possibly damaging	0.86
R2830:Ankrd11	UTSW	8	123,618,935 (GRCm39)	missense	probably damaging	1.00
R2910:Ankrd11	UTSW	8	123,635,537 (GRCm39)	missense	probably damaging	1.00
R2911:Ankrd11	UTSW	8	123,635,537 (GRCm39)	missense	probably damaging	1.00
R3736:Ankrd11	UTSW	8	123,618,524 (GRCm39)	missense	probably damaging	0.97
R3738:Ankrd11	UTSW	8	123,623,454 (GRCm39)	unclassified	probably benign
R3739:Ankrd11	UTSW	8	123,623,454 (GRCm39)	unclassified	probably benign
R3813:Ankrd11	UTSW	8	123,618,117 (GRCm39)	missense	probably benign
R4012:Ankrd11	UTSW	8	123,619,156 (GRCm39)	missense	probably damaging	0.98
R4183:Ankrd11	UTSW	8	123,626,415 (GRCm39)	missense	possibly damaging	0.88
R4213:Ankrd11	UTSW	8	123,617,765 (GRCm39)	missense	probably benign	0.00
R4469:Ankrd11	UTSW	8	123,623,326 (GRCm39)	missense	probably damaging	1.00
R4482:Ankrd11	UTSW	8	123,620,228 (GRCm39)	missense	probably damaging	1.00
R4935:Ankrd11	UTSW	8	123,626,922 (GRCm39)	missense	probably benign	0.02
R4940:Ankrd11	UTSW	8	123,616,560 (GRCm39)	missense	probably damaging	1.00
R5145:Ankrd11	UTSW	8	123,617,943 (GRCm39)	utr 3 prime	probably benign
R5154:Ankrd11	UTSW	8	123,619,878 (GRCm39)	missense	probably damaging	1.00
R5230:Ankrd11	UTSW	8	123,617,216 (GRCm39)	missense	probably benign	0.11
R5283:Ankrd11	UTSW	8	123,610,921 (GRCm39)	missense	probably damaging	1.00
R5377:Ankrd11	UTSW	8	123,620,453 (GRCm39)	splice site	probably null
R5513:Ankrd11	UTSW	8	123,619,259 (GRCm39)	missense	probably benign	0.38
R5518:Ankrd11	UTSW	8	123,617,733 (GRCm39)	missense	possibly damaging	0.93
R5549:Ankrd11	UTSW	8	123,617,117 (GRCm39)	missense	probably benign	0.02
R5579:Ankrd11	UTSW	8	123,610,970 (GRCm39)	missense	probably damaging	0.97
R5595:Ankrd11	UTSW	8	123,621,043 (GRCm39)	nonsense	probably null
R5650:Ankrd11	UTSW	8	123,614,136 (GRCm39)	missense	probably damaging	0.99
R5717:Ankrd11	UTSW	8	123,619,377 (GRCm39)	missense	possibly damaging	0.92
R5753:Ankrd11	UTSW	8	123,622,043 (GRCm39)	missense	possibly damaging	0.90
R5782:Ankrd11	UTSW	8	123,626,756 (GRCm39)	missense	probably damaging	1.00
R5812:Ankrd11	UTSW	8	123,620,544 (GRCm39)	splice site	probably null
R5823:Ankrd11	UTSW	8	123,622,529 (GRCm39)	missense	probably benign	0.12
R5900:Ankrd11	UTSW	8	123,617,805 (GRCm39)	missense	probably benign	0.00
R5975:Ankrd11	UTSW	8	123,616,488 (GRCm39)	missense	possibly damaging	0.93
R5979:Ankrd11	UTSW	8	123,619,139 (GRCm39)	missense	probably damaging	1.00
R6145:Ankrd11	UTSW	8	123,619,400 (GRCm39)	missense	probably damaging	1.00
R6252:Ankrd11	UTSW	8	123,620,561 (GRCm39)	missense	possibly damaging	0.87
R6302:Ankrd11	UTSW	8	123,616,728 (GRCm39)	missense	probably benign
R6457:Ankrd11	UTSW	8	123,635,503 (GRCm39)	missense	probably damaging	1.00
R6513:Ankrd11	UTSW	8	123,616,919 (GRCm39)	missense	probably benign	0.02
R6582:Ankrd11	UTSW	8	123,618,368 (GRCm39)	missense	probably benign	0.00
R6738:Ankrd11	UTSW	8	123,618,660 (GRCm39)	missense	probably damaging	0.99
R6865:Ankrd11	UTSW	8	123,621,683 (GRCm39)	missense	probably benign	0.41
R6913:Ankrd11	UTSW	8	123,621,650 (GRCm39)	missense	probably benign	0.01
R7101:Ankrd11	UTSW	8	123,622,194 (GRCm39)	missense	probably benign	0.35
R7116:Ankrd11	UTSW	8	123,622,869 (GRCm39)	missense	probably damaging	1.00
R7477:Ankrd11	UTSW	8	123,621,124 (GRCm39)	missense	possibly damaging	0.91
R7534:Ankrd11	UTSW	8	123,621,149 (GRCm39)	missense	probably damaging	1.00
R7555:Ankrd11	UTSW	8	123,614,145 (GRCm39)	missense	probably damaging	0.99
R7627:Ankrd11	UTSW	8	123,617,690 (GRCm39)	missense	possibly damaging	0.63
R7658:Ankrd11	UTSW	8	123,620,403 (GRCm39)	missense	probably benign
R7721:Ankrd11	UTSW	8	123,621,498 (GRCm39)	missense	probably damaging	1.00
R7731:Ankrd11	UTSW	8	123,622,172 (GRCm39)	missense	probably benign	0.12
R7792:Ankrd11	UTSW	8	123,610,970 (GRCm39)	missense	probably damaging	0.97
R7924:Ankrd11	UTSW	8	123,622,641 (GRCm39)	missense	possibly damaging	0.95
R7939:Ankrd11	UTSW	8	123,617,812 (GRCm39)	missense	probably damaging	1.00
R8022:Ankrd11	UTSW	8	123,614,332 (GRCm39)	missense	probably damaging	1.00
R8222:Ankrd11	UTSW	8	123,622,347 (GRCm39)	missense	probably damaging	0.98
R8362:Ankrd11	UTSW	8	123,618,797 (GRCm39)	missense	probably damaging	0.96
R8430:Ankrd11	UTSW	8	123,620,105 (GRCm39)	missense	probably benign	0.01
R8511:Ankrd11	UTSW	8	123,626,468 (GRCm39)	missense
R8726:Ankrd11	UTSW	8	123,620,765 (GRCm39)	missense	possibly damaging	0.90
R8888:Ankrd11	UTSW	8	123,621,014 (GRCm39)	missense	possibly damaging	0.87
R8895:Ankrd11	UTSW	8	123,621,014 (GRCm39)	missense	possibly damaging	0.87
R8928:Ankrd11	UTSW	8	123,622,718 (GRCm39)	missense	probably damaging	0.99
R8930:Ankrd11	UTSW	8	123,622,718 (GRCm39)	missense	probably damaging	0.99
R8931:Ankrd11	UTSW	8	123,622,718 (GRCm39)	missense	probably damaging	0.99
R8936:Ankrd11	UTSW	8	123,621,840 (GRCm39)	missense	possibly damaging	0.69
R9018:Ankrd11	UTSW	8	123,622,251 (GRCm39)	missense	probably damaging	1.00
R9113:Ankrd11	UTSW	8	123,614,072 (GRCm39)	missense	possibly damaging	0.60
R9399:Ankrd11	UTSW	8	123,618,179 (GRCm39)	missense	probably benign
R9644:Ankrd11	UTSW	8	123,617,682 (GRCm39)	missense	probably benign	0.00
R9645:Ankrd11	UTSW	8	123,617,682 (GRCm39)	missense	probably benign	0.00
R9647:Ankrd11	UTSW	8	123,617,682 (GRCm39)	missense	probably benign	0.00
R9683:Ankrd11	UTSW	8	123,617,682 (GRCm39)	missense	probably benign	0.00
RF019:Ankrd11	UTSW	8	123,623,373 (GRCm39)	missense	probably damaging	1.00
Z1176:Ankrd11	UTSW	8	123,622,542 (GRCm39)	missense	possibly damaging	0.68
Z1177:Ankrd11	UTSW	8	123,626,881 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CGGCAAAGGGTAAGATCCTG -3'
(R):5'- CCTAGAGGTGAACTGCTGAG -3'

Sequencing Primer
(F):5'- CAAAGGGTAAGATCCTGGAGAGAC -3'
(R):5'- TGAGCCCAGCCATTGAAG -3'

Posted On

2017-06-26