Incidental Mutation 'R0514:Anapc1'
| ID |
48080 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Anapc1
|
| Ensembl Gene |
ENSMUSG00000014355 |
| Gene Name |
anaphase promoting complex subunit 1 |
| Synonyms |
Apc1, tsg24, Mcpr, 2610021O03Rik |
| MMRRC Submission |
038708-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0514 (G1)
|
| Quality Score |
180 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
128452024-128529311 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 128474575 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Phenylalanine
at position 1413
(L1413F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000014499
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014499]
|
| AlphaFold |
P53995 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000014499
AA Change: L1413F
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000014499
Gene: ENSMUSG00000014355
AA Change: L1413F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ANAPC1
|
150 |
214 |
1.7e-13 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1415 |
N/A |
INTRINSIC |
|
Pfam:PC_rep
|
1467 |
1501 |
8.3e-8 |
PFAM |
|
low complexity region
|
1516 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1924 |
1936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154320
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154995
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acp3 |
T |
A |
9: 104,197,177 (GRCm39) |
Y154F |
probably damaging |
Het |
| Acsl6 |
A |
T |
11: 54,241,406 (GRCm39) |
D579V |
probably damaging |
Het |
| Adamts18 |
C |
T |
8: 114,465,401 (GRCm39) |
|
probably null |
Het |
| Adamts20 |
A |
T |
15: 94,168,257 (GRCm39) |
V1882D |
probably damaging |
Het |
| Add3 |
A |
T |
19: 53,225,274 (GRCm39) |
K465* |
probably null |
Het |
| Ago1 |
T |
G |
4: 126,333,388 (GRCm39) |
I524L |
probably benign |
Het |
| Akr1c18 |
A |
G |
13: 4,187,190 (GRCm39) |
M208T |
probably benign |
Het |
| Arid4b |
A |
T |
13: 14,358,902 (GRCm39) |
D646V |
probably damaging |
Het |
| Arnt2 |
T |
C |
7: 83,954,067 (GRCm39) |
E261G |
probably benign |
Het |
| Bccip |
C |
T |
7: 133,320,859 (GRCm39) |
T211I |
possibly damaging |
Het |
| Bsn |
T |
C |
9: 108,002,981 (GRCm39) |
S475G |
probably benign |
Het |
| Cdh26 |
G |
A |
2: 178,108,621 (GRCm39) |
|
probably null |
Het |
| Ceacam2 |
A |
G |
7: 25,220,356 (GRCm39) |
F414S |
probably benign |
Het |
| Cep43 |
A |
G |
17: 8,410,266 (GRCm39) |
N342S |
possibly damaging |
Het |
| Cfb |
T |
C |
17: 35,079,874 (GRCm39) |
R172G |
probably damaging |
Het |
| Cntnap5b |
A |
C |
1: 99,700,511 (GRCm39) |
T8P |
probably benign |
Het |
| Cpne9 |
A |
T |
6: 113,266,974 (GRCm39) |
I136L |
probably damaging |
Het |
| Crtc1 |
A |
T |
8: 70,855,079 (GRCm39) |
|
probably null |
Het |
| Dcdc2a |
A |
T |
13: 25,303,369 (GRCm39) |
H300L |
probably benign |
Het |
| Dhdh |
C |
T |
7: 45,138,130 (GRCm39) |
V20M |
probably benign |
Het |
| Dhx34 |
T |
C |
7: 15,944,462 (GRCm39) |
Q584R |
probably benign |
Het |
| Dis3l2 |
A |
G |
1: 86,974,814 (GRCm39) |
Y701C |
probably damaging |
Het |
| Dmrt2 |
T |
C |
19: 25,653,019 (GRCm39) |
|
probably null |
Het |
| Dnah5 |
A |
G |
15: 28,366,467 (GRCm39) |
T2727A |
probably damaging |
Het |
| Dop1a |
A |
G |
9: 86,402,787 (GRCm39) |
E1329G |
probably damaging |
Het |
| Evpl |
A |
G |
11: 116,114,117 (GRCm39) |
V1191A |
probably damaging |
Het |
| Fhl4 |
T |
C |
10: 84,934,250 (GRCm39) |
D177G |
probably damaging |
Het |
| Gask1a |
A |
G |
9: 121,807,418 (GRCm39) |
T521A |
possibly damaging |
Het |
| Heg1 |
A |
G |
16: 33,547,126 (GRCm39) |
T662A |
possibly damaging |
Het |
| Ifih1 |
A |
G |
2: 62,453,735 (GRCm39) |
|
probably null |
Het |
| Il13 |
T |
C |
11: 53,523,345 (GRCm39) |
R87G |
possibly damaging |
Het |
| Kcnc3 |
T |
A |
7: 44,245,352 (GRCm39) |
Y547* |
probably null |
Het |
| Krt81 |
C |
A |
15: 101,361,508 (GRCm39) |
R24L |
possibly damaging |
Het |
| Lama1 |
G |
A |
17: 68,071,693 (GRCm39) |
G860D |
probably benign |
Het |
| Lmo7 |
T |
C |
14: 102,124,609 (GRCm39) |
L356P |
probably damaging |
Het |
| Lmo7 |
A |
T |
14: 102,133,995 (GRCm39) |
K447I |
probably damaging |
Het |
| Lrp2bp |
A |
G |
8: 46,464,995 (GRCm39) |
H38R |
probably damaging |
Het |
| Magi3 |
G |
A |
3: 103,922,338 (GRCm39) |
P1460S |
probably damaging |
Het |
| Megf8 |
T |
A |
7: 25,063,728 (GRCm39) |
C2695S |
possibly damaging |
Het |
| Mrgprb2 |
T |
G |
7: 48,201,718 (GRCm39) |
S336R |
probably benign |
Het |
| Mrgprx2 |
C |
T |
7: 48,132,712 (GRCm39) |
M1I |
probably null |
Het |
| Mug2 |
T |
C |
6: 122,058,558 (GRCm39) |
L1320P |
probably damaging |
Het |
| Noxred1 |
A |
G |
12: 87,273,838 (GRCm39) |
S68P |
probably benign |
Het |
| Or51f5 |
T |
A |
7: 102,424,539 (GRCm39) |
H269Q |
probably benign |
Het |
| Or56b1b |
T |
A |
7: 108,164,879 (GRCm39) |
Y41F |
probably damaging |
Het |
| Os9 |
C |
T |
10: 126,955,508 (GRCm39) |
C123Y |
probably damaging |
Het |
| Ostf1 |
T |
A |
19: 18,573,723 (GRCm39) |
T42S |
probably benign |
Het |
| Parg |
C |
A |
14: 31,976,517 (GRCm39) |
T186K |
possibly damaging |
Het |
| Pcnx1 |
T |
A |
12: 82,041,884 (GRCm39) |
M2172K |
probably benign |
Het |
| Pip4k2a |
A |
G |
2: 18,850,747 (GRCm39) |
I360T |
probably damaging |
Het |
| Pkn2 |
T |
C |
3: 142,516,219 (GRCm39) |
D568G |
possibly damaging |
Het |
| Plch2 |
A |
G |
4: 155,083,343 (GRCm39) |
S431P |
probably damaging |
Het |
| Prl8a6 |
A |
T |
13: 27,616,990 (GRCm39) |
C233* |
probably null |
Het |
| Prox1 |
G |
A |
1: 189,893,653 (GRCm39) |
T264I |
probably damaging |
Het |
| Prr5 |
A |
G |
15: 84,586,967 (GRCm39) |
N248S |
probably benign |
Het |
| Psip1 |
A |
C |
4: 83,378,274 (GRCm39) |
S407R |
probably damaging |
Het |
| Rab32 |
A |
T |
10: 10,426,640 (GRCm39) |
V102E |
probably damaging |
Het |
| Rap1gap2 |
T |
G |
11: 74,279,680 (GRCm39) |
K687Q |
possibly damaging |
Het |
| Rbak |
A |
T |
5: 143,159,169 (GRCm39) |
V628E |
probably damaging |
Het |
| Rnf148 |
T |
C |
6: 23,654,792 (GRCm39) |
E68G |
possibly damaging |
Het |
| Rnf212 |
A |
T |
5: 108,897,308 (GRCm39) |
S3T |
probably damaging |
Het |
| Rrad |
T |
G |
8: 105,355,259 (GRCm39) |
I250L |
probably benign |
Het |
| Sall4 |
T |
C |
2: 168,597,625 (GRCm39) |
H405R |
probably damaging |
Het |
| Scn9a |
T |
C |
2: 66,314,022 (GRCm39) |
R1888G |
probably damaging |
Het |
| Setd5 |
G |
T |
6: 113,096,398 (GRCm39) |
E535* |
probably null |
Het |
| Slc20a1 |
C |
T |
2: 129,041,811 (GRCm39) |
S58L |
probably damaging |
Het |
| Slc31a1 |
A |
G |
4: 62,303,841 (GRCm39) |
|
probably benign |
Het |
| Slc38a11 |
G |
T |
2: 65,147,209 (GRCm39) |
Q423K |
probably benign |
Het |
| Snrpd1 |
A |
T |
18: 10,626,846 (GRCm39) |
T38S |
possibly damaging |
Het |
| Taar4 |
A |
G |
10: 23,836,780 (GRCm39) |
D130G |
probably damaging |
Het |
| Tfb2m |
C |
T |
1: 179,358,869 (GRCm39) |
R338H |
probably benign |
Het |
| Tm2d2 |
A |
G |
8: 25,512,742 (GRCm39) |
I197V |
possibly damaging |
Het |
| Tmem132a |
C |
T |
19: 10,836,355 (GRCm39) |
G725D |
probably damaging |
Het |
| Tmem67 |
T |
C |
4: 12,089,317 (GRCm39) |
T38A |
probably benign |
Het |
| Tmprss15 |
A |
T |
16: 78,765,155 (GRCm39) |
S816T |
probably benign |
Het |
| Tnfrsf11a |
A |
G |
1: 105,754,717 (GRCm39) |
E263G |
probably damaging |
Het |
| Tnfrsf17 |
C |
T |
16: 11,133,191 (GRCm39) |
L90F |
probably benign |
Het |
| Tpr |
A |
G |
1: 150,278,024 (GRCm39) |
K117E |
possibly damaging |
Het |
| Trim43a |
C |
T |
9: 88,466,389 (GRCm39) |
Q5* |
probably null |
Het |
| Ubn1 |
A |
T |
16: 4,890,935 (GRCm39) |
D498V |
probably damaging |
Het |
| Vipr1 |
T |
A |
9: 121,487,115 (GRCm39) |
C63S |
probably damaging |
Het |
| Vmn1r237 |
T |
A |
17: 21,534,932 (GRCm39) |
H218Q |
possibly damaging |
Het |
| Vmn2r100 |
C |
A |
17: 19,742,382 (GRCm39) |
P252Q |
possibly damaging |
Het |
| Vmn2r95 |
T |
C |
17: 18,671,844 (GRCm39) |
V527A |
probably benign |
Het |
| Vmn2r97 |
A |
T |
17: 19,134,734 (GRCm39) |
T51S |
probably benign |
Het |
| Vwa8 |
G |
A |
14: 79,184,629 (GRCm39) |
V376I |
probably benign |
Het |
| Wdfy4 |
T |
A |
14: 32,802,732 (GRCm39) |
T1838S |
probably benign |
Het |
| Zcwpw1 |
A |
T |
5: 137,794,945 (GRCm39) |
E47V |
probably benign |
Het |
| Zeb2 |
T |
C |
2: 44,892,659 (GRCm39) |
E130G |
possibly damaging |
Het |
| Zfp111 |
A |
G |
7: 23,898,568 (GRCm39) |
Y348H |
probably damaging |
Het |
| Zfp53 |
T |
C |
17: 21,729,271 (GRCm39) |
S435P |
probably damaging |
Het |
|
| Other mutations in Anapc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Anapc1
|
APN |
2 |
128,487,050 (GRCm39) |
splice site |
probably benign |
|
|
IGL00704:Anapc1
|
APN |
2 |
128,505,904 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01023:Anapc1
|
APN |
2 |
128,471,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01432:Anapc1
|
APN |
2 |
128,475,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Anapc1
|
APN |
2 |
128,495,090 (GRCm39) |
missense |
probably benign |
|
|
IGL02089:Anapc1
|
APN |
2 |
128,505,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02275:Anapc1
|
APN |
2 |
128,501,772 (GRCm39) |
missense |
probably benign |
|
|
IGL02570:Anapc1
|
APN |
2 |
128,487,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Anapc1
|
APN |
2 |
128,465,851 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02726:Anapc1
|
APN |
2 |
128,501,705 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03265:Anapc1
|
APN |
2 |
128,469,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03304:Anapc1
|
APN |
2 |
128,469,033 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Anapc1
|
APN |
2 |
128,465,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0023:Anapc1
|
UTSW |
2 |
128,520,138 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0084:Anapc1
|
UTSW |
2 |
128,465,886 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0255:Anapc1
|
UTSW |
2 |
128,476,631 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0377:Anapc1
|
UTSW |
2 |
128,483,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0467:Anapc1
|
UTSW |
2 |
128,510,963 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0591:Anapc1
|
UTSW |
2 |
128,461,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0919:Anapc1
|
UTSW |
2 |
128,459,651 (GRCm39) |
missense |
probably benign |
|
|
R1175:Anapc1
|
UTSW |
2 |
128,522,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Anapc1
|
UTSW |
2 |
128,459,617 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1547:Anapc1
|
UTSW |
2 |
128,459,476 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1556:Anapc1
|
UTSW |
2 |
128,466,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1567:Anapc1
|
UTSW |
2 |
128,459,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Anapc1
|
UTSW |
2 |
128,470,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1645:Anapc1
|
UTSW |
2 |
128,500,166 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1677:Anapc1
|
UTSW |
2 |
128,518,128 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1854:Anapc1
|
UTSW |
2 |
128,517,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1856:Anapc1
|
UTSW |
2 |
128,501,708 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1959:Anapc1
|
UTSW |
2 |
128,475,335 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1984:Anapc1
|
UTSW |
2 |
128,511,608 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2034:Anapc1
|
UTSW |
2 |
128,490,378 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2283:Anapc1
|
UTSW |
2 |
128,484,468 (GRCm39) |
missense |
probably benign |
0.23 |
|
R2928:Anapc1
|
UTSW |
2 |
128,522,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Anapc1
|
UTSW |
2 |
128,484,602 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R3904:Anapc1
|
UTSW |
2 |
128,484,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Anapc1
|
UTSW |
2 |
128,469,149 (GRCm39) |
intron |
probably benign |
|
|
R4359:Anapc1
|
UTSW |
2 |
128,465,476 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4392:Anapc1
|
UTSW |
2 |
128,518,169 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4574:Anapc1
|
UTSW |
2 |
128,469,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Anapc1
|
UTSW |
2 |
128,505,925 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4770:Anapc1
|
UTSW |
2 |
128,527,980 (GRCm39) |
splice site |
probably benign |
|
|
R4824:Anapc1
|
UTSW |
2 |
128,470,610 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4960:Anapc1
|
UTSW |
2 |
128,526,514 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5016:Anapc1
|
UTSW |
2 |
128,449,095 (GRCm39) |
unclassified |
probably benign |
|
|
R5063:Anapc1
|
UTSW |
2 |
128,471,469 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5128:Anapc1
|
UTSW |
2 |
128,501,837 (GRCm39) |
missense |
probably benign |
|
|
R5271:Anapc1
|
UTSW |
2 |
128,527,905 (GRCm39) |
nonsense |
probably null |
|
|
R5363:Anapc1
|
UTSW |
2 |
128,492,114 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5469:Anapc1
|
UTSW |
2 |
128,517,621 (GRCm39) |
nonsense |
probably null |
|
|
R5473:Anapc1
|
UTSW |
2 |
128,449,115 (GRCm39) |
unclassified |
probably benign |
|
|
R5559:Anapc1
|
UTSW |
2 |
128,522,354 (GRCm39) |
nonsense |
probably null |
|
|
R5631:Anapc1
|
UTSW |
2 |
128,499,137 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5747:Anapc1
|
UTSW |
2 |
128,466,836 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5840:Anapc1
|
UTSW |
2 |
128,448,957 (GRCm39) |
unclassified |
probably benign |
|
|
R6226:Anapc1
|
UTSW |
2 |
128,492,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Anapc1
|
UTSW |
2 |
128,514,055 (GRCm39) |
nonsense |
probably null |
|
|
R6561:Anapc1
|
UTSW |
2 |
128,505,919 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6743:Anapc1
|
UTSW |
2 |
128,526,454 (GRCm39) |
nonsense |
probably null |
|
|
R6799:Anapc1
|
UTSW |
2 |
128,501,657 (GRCm39) |
missense |
probably null |
0.38 |
|
R6887:Anapc1
|
UTSW |
2 |
128,501,688 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6978:Anapc1
|
UTSW |
2 |
128,511,820 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7011:Anapc1
|
UTSW |
2 |
128,490,601 (GRCm39) |
splice site |
probably null |
|
|
R7041:Anapc1
|
UTSW |
2 |
128,470,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7047:Anapc1
|
UTSW |
2 |
128,457,350 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7074:Anapc1
|
UTSW |
2 |
128,520,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Anapc1
|
UTSW |
2 |
128,516,522 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7123:Anapc1
|
UTSW |
2 |
128,454,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7309:Anapc1
|
UTSW |
2 |
128,516,604 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7693:Anapc1
|
UTSW |
2 |
128,483,457 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7839:Anapc1
|
UTSW |
2 |
128,526,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7847:Anapc1
|
UTSW |
2 |
128,511,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7960:Anapc1
|
UTSW |
2 |
128,516,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Anapc1
|
UTSW |
2 |
128,490,408 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8127:Anapc1
|
UTSW |
2 |
128,474,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8228:Anapc1
|
UTSW |
2 |
128,461,837 (GRCm39) |
nonsense |
probably null |
|
|
R8402:Anapc1
|
UTSW |
2 |
128,472,148 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8422:Anapc1
|
UTSW |
2 |
128,517,757 (GRCm39) |
missense |
probably benign |
|
|
R8425:Anapc1
|
UTSW |
2 |
128,511,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8469:Anapc1
|
UTSW |
2 |
128,500,264 (GRCm39) |
splice site |
probably null |
|
|
R8553:Anapc1
|
UTSW |
2 |
128,461,833 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8688:Anapc1
|
UTSW |
2 |
128,527,748 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8699:Anapc1
|
UTSW |
2 |
128,483,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8719:Anapc1
|
UTSW |
2 |
128,483,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8775-TAIL:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8806:Anapc1
|
UTSW |
2 |
128,464,333 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8973:Anapc1
|
UTSW |
2 |
128,505,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8977:Anapc1
|
UTSW |
2 |
128,483,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9000:Anapc1
|
UTSW |
2 |
128,476,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9080:Anapc1
|
UTSW |
2 |
128,464,426 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9203:Anapc1
|
UTSW |
2 |
128,465,422 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9314:Anapc1
|
UTSW |
2 |
128,464,420 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9386:Anapc1
|
UTSW |
2 |
128,459,642 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9415:Anapc1
|
UTSW |
2 |
128,476,598 (GRCm39) |
missense |
probably benign |
|
|
R9436:Anapc1
|
UTSW |
2 |
128,518,045 (GRCm39) |
missense |
probably benign |
|
|
R9516:Anapc1
|
UTSW |
2 |
128,517,633 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9563:Anapc1
|
UTSW |
2 |
128,505,980 (GRCm39) |
nonsense |
probably null |
|
|
R9572:Anapc1
|
UTSW |
2 |
128,505,976 (GRCm39) |
missense |
probably benign |
|
|
R9757:Anapc1
|
UTSW |
2 |
128,517,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9766:Anapc1
|
UTSW |
2 |
128,500,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Anapc1
|
UTSW |
2 |
128,516,621 (GRCm39) |
missense |
probably benign |
0.10 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGGAAGACCTGGACATTTTAGCTGTG -3'
(R):5'- CTCCAAACCCTCAATACTTGGATCGTG -3'
Sequencing Primer
(F):5'- tccttacgcaccagcatc -3'
(R):5'- GTTGTTAGTTGGGAACGAATTCTTAG -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation