Incidental Mutation 'R5979:Phf3'
| ID |
481275 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phf3
|
| Ensembl Gene |
ENSMUSG00000048874 |
| Gene Name |
PHD finger protein 3 |
| Synonyms |
AU020177, 2310061N19Rik |
| MMRRC Submission |
044161-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5979 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
30841417-30912989 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 30844827 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 1377
(F1377L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000139610
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000088310]
[ENSMUST00000186733]
[ENSMUST00000191329]
|
| AlphaFold |
B2RQG2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000088310
AA Change: F1377L
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000085650
Gene: ENSMUSG00000048874
AA Change: F1377L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
337 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
660 |
N/A |
INTRINSIC |
|
PHD
|
697 |
748 |
3.82e-10 |
SMART |
|
low complexity region
|
847 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
876 |
887 |
N/A |
INTRINSIC |
|
TFS2M
|
908 |
1008 |
1.28e-47 |
SMART |
|
Pfam:SPOC
|
1188 |
1294 |
4.2e-26 |
PFAM |
|
low complexity region
|
1367 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1516 |
1529 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1620 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1811 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1846 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000186733
AA Change: F1377L
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000139610
Gene: ENSMUSG00000048874
AA Change: F1377L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
337 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
660 |
N/A |
INTRINSIC |
|
PHD
|
697 |
748 |
3.82e-10 |
SMART |
|
low complexity region
|
847 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
876 |
887 |
N/A |
INTRINSIC |
|
TFS2M
|
908 |
1008 |
1.28e-47 |
SMART |
|
Pfam:SPOC
|
1188 |
1294 |
4.2e-26 |
PFAM |
|
low complexity region
|
1367 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1516 |
1529 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1620 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1811 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1846 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000190190
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191329
|
| SMART Domains |
Protein: ENSMUSP00000139662
Gene: ENSMUSG00000048874
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:SPOC
|
1 |
88 |
1.9e-17 |
PFAM |
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.4%
- 20x: 95.4%
|
| Validation Efficiency |
100% (87/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acss2 |
A |
G |
2: 155,364,029 (GRCm39) |
I103V |
possibly damaging |
Het |
| Adam3 |
T |
C |
8: 25,167,383 (GRCm39) |
N36S |
probably benign |
Het |
| Adamts3 |
A |
G |
5: 90,009,528 (GRCm39) |
V45A |
probably damaging |
Het |
| Afg3l2 |
G |
T |
18: 67,554,329 (GRCm39) |
L458M |
probably damaging |
Het |
| Agtpbp1 |
A |
T |
13: 59,681,860 (GRCm39) |
L69* |
probably null |
Het |
| Alkbh5 |
T |
A |
11: 60,429,517 (GRCm39) |
I90N |
probably damaging |
Het |
| Alx1 |
T |
C |
10: 102,858,120 (GRCm39) |
Y193C |
probably damaging |
Het |
| Ankrd11 |
T |
G |
8: 123,619,139 (GRCm39) |
D1571A |
probably damaging |
Het |
| Brd4 |
T |
C |
17: 32,417,700 (GRCm39) |
D124G |
probably benign |
Het |
| C2cd2 |
G |
A |
16: 97,676,418 (GRCm39) |
T443I |
probably benign |
Het |
| Casp8 |
A |
T |
1: 58,868,071 (GRCm39) |
M171L |
probably benign |
Het |
| Cd200r4 |
G |
A |
16: 44,653,295 (GRCm39) |
V22I |
probably benign |
Het |
| Cdcp2 |
A |
G |
4: 106,962,478 (GRCm39) |
Y217C |
probably damaging |
Het |
| Cfh |
C |
A |
1: 140,046,409 (GRCm39) |
V556F |
possibly damaging |
Het |
| Chka |
T |
G |
19: 3,934,513 (GRCm39) |
I182M |
probably damaging |
Het |
| Cope |
T |
C |
8: 70,755,193 (GRCm39) |
|
probably null |
Het |
| Coq10b |
T |
C |
1: 55,092,077 (GRCm39) |
V15A |
probably benign |
Het |
| Cpne9 |
T |
A |
6: 113,270,710 (GRCm39) |
S309T |
probably benign |
Het |
| Daam2 |
T |
A |
17: 49,766,232 (GRCm39) |
H992L |
possibly damaging |
Het |
| Dctn3 |
T |
C |
4: 41,715,393 (GRCm39) |
|
probably null |
Het |
| Dhx35 |
G |
T |
2: 158,684,789 (GRCm39) |
R536L |
probably benign |
Het |
| Dnah8 |
G |
T |
17: 31,034,638 (GRCm39) |
E4186* |
probably null |
Het |
| Dnah9 |
A |
G |
11: 65,725,307 (GRCm39) |
L4282P |
probably damaging |
Het |
| Dpp10 |
A |
G |
1: 123,312,012 (GRCm39) |
|
probably null |
Het |
| Dst |
T |
A |
1: 34,199,453 (GRCm39) |
|
probably benign |
Het |
| Ehbp1 |
C |
A |
11: 22,101,887 (GRCm39) |
V214L |
probably benign |
Het |
| Fam131b |
T |
C |
6: 42,298,905 (GRCm39) |
D25G |
probably damaging |
Het |
| Fbxl13 |
T |
A |
5: 21,787,089 (GRCm39) |
I283F |
probably damaging |
Het |
| Gabrr3 |
T |
G |
16: 59,254,931 (GRCm39) |
N205K |
possibly damaging |
Het |
| Got1l1 |
C |
T |
8: 27,687,951 (GRCm39) |
|
probably null |
Het |
| Gprin1 |
G |
A |
13: 54,887,791 (GRCm39) |
A161V |
probably benign |
Het |
| Hepacam2 |
A |
T |
6: 3,476,149 (GRCm39) |
F183I |
probably damaging |
Het |
| Hmx2 |
A |
G |
7: 131,156,279 (GRCm39) |
T82A |
probably benign |
Het |
| Igsf10 |
C |
T |
3: 59,243,894 (GRCm39) |
E147K |
probably damaging |
Het |
| Kndc1 |
G |
A |
7: 139,519,740 (GRCm39) |
A1700T |
probably benign |
Het |
| Knl1 |
T |
C |
2: 118,899,841 (GRCm39) |
V514A |
possibly damaging |
Het |
| Lama2 |
T |
C |
10: 27,111,728 (GRCm39) |
D764G |
probably damaging |
Het |
| Lgi3 |
G |
A |
14: 70,773,900 (GRCm39) |
R358H |
probably damaging |
Het |
| Limd1 |
G |
T |
9: 123,308,479 (GRCm39) |
Q59H |
possibly damaging |
Het |
| Lrrk2 |
A |
G |
15: 91,657,148 (GRCm39) |
Y1814C |
possibly damaging |
Het |
| Lysmd3 |
G |
A |
13: 81,813,393 (GRCm39) |
|
probably null |
Het |
| Mroh7 |
T |
C |
4: 106,578,123 (GRCm39) |
N185S |
probably benign |
Het |
| Muc2 |
A |
G |
7: 141,283,493 (GRCm39) |
|
probably null |
Het |
| Muc2 |
G |
A |
7: 141,305,143 (GRCm39) |
G149D |
probably damaging |
Het |
| Nlrp3 |
T |
C |
11: 59,439,797 (GRCm39) |
F458S |
probably benign |
Het |
| Nop58 |
A |
T |
1: 59,741,990 (GRCm39) |
D173V |
probably damaging |
Het |
| Nrxn1 |
C |
T |
17: 91,395,631 (GRCm39) |
R175H |
possibly damaging |
Het |
| Nxpe4 |
A |
G |
9: 48,307,862 (GRCm39) |
N322S |
probably benign |
Het |
| Ocstamp |
A |
G |
2: 165,239,467 (GRCm39) |
S240P |
probably damaging |
Het |
| Or10a5 |
G |
A |
7: 106,635,543 (GRCm39) |
M60I |
probably damaging |
Het |
| Or2j3 |
T |
C |
17: 38,616,083 (GRCm39) |
K90E |
probably benign |
Het |
| Or8b36 |
ATTGCTGTTT |
ATTGCTGTTTGCTGTTT |
9: 37,937,836 (GRCm39) |
|
probably null |
Het |
| Or9e1 |
A |
G |
11: 58,732,666 (GRCm39) |
H242R |
probably damaging |
Het |
| Ovch2 |
G |
A |
7: 107,393,595 (GRCm39) |
T177I |
possibly damaging |
Het |
| Parn |
A |
C |
16: 13,424,035 (GRCm39) |
L454R |
probably damaging |
Het |
| Pcdhb12 |
T |
A |
18: 37,571,044 (GRCm39) |
L730Q |
possibly damaging |
Het |
| Pign |
G |
T |
1: 105,516,999 (GRCm39) |
S542R |
probably benign |
Het |
| Prex2 |
G |
T |
1: 11,202,596 (GRCm39) |
V502F |
probably damaging |
Het |
| Psmd1 |
A |
T |
1: 86,017,775 (GRCm39) |
I529F |
possibly damaging |
Het |
| Ptafr |
A |
G |
4: 132,306,616 (GRCm39) |
E2G |
probably benign |
Het |
| R3hdm1 |
A |
G |
1: 128,138,960 (GRCm39) |
N380S |
probably benign |
Het |
| Rbm12 |
A |
C |
2: 155,939,679 (GRCm39) |
|
probably benign |
Het |
| Rgl1 |
A |
G |
1: 152,433,244 (GRCm39) |
Y174H |
probably damaging |
Het |
| Rps6kc1 |
A |
G |
1: 190,532,632 (GRCm39) |
S457P |
probably damaging |
Het |
| Sall4 |
A |
T |
2: 168,592,263 (GRCm39) |
S964T |
probably benign |
Het |
| Sart1 |
T |
A |
19: 5,431,251 (GRCm39) |
I681F |
probably damaging |
Het |
| Serinc5 |
T |
C |
13: 92,797,644 (GRCm39) |
L49P |
probably benign |
Het |
| Serpinb9e |
T |
C |
13: 33,439,036 (GRCm39) |
V154A |
probably benign |
Het |
| Skic2 |
A |
T |
17: 35,060,439 (GRCm39) |
N851K |
probably benign |
Het |
| Smox |
G |
A |
2: 131,358,334 (GRCm39) |
V136I |
probably damaging |
Het |
| Sspo |
C |
T |
6: 48,440,627 (GRCm39) |
T1747I |
probably benign |
Het |
| Swt1 |
A |
T |
1: 151,283,339 (GRCm39) |
D339E |
possibly damaging |
Het |
| Synpo2 |
A |
G |
3: 122,911,060 (GRCm39) |
L195P |
probably damaging |
Het |
| Syt7 |
G |
T |
19: 10,420,843 (GRCm39) |
G414W |
probably damaging |
Het |
| Tmem186 |
G |
A |
16: 8,454,024 (GRCm39) |
T79I |
probably damaging |
Het |
| Tmem39a |
A |
T |
16: 38,396,106 (GRCm39) |
N113I |
probably damaging |
Het |
| Trim14 |
C |
T |
4: 46,507,239 (GRCm39) |
V326M |
probably damaging |
Het |
| Trim58 |
A |
G |
11: 58,536,909 (GRCm39) |
E234G |
probably damaging |
Het |
| Ttr |
T |
C |
18: 20,803,059 (GRCm39) |
L75P |
probably damaging |
Het |
| Ubr1 |
C |
T |
2: 120,776,863 (GRCm39) |
V293I |
probably benign |
Het |
| Vmn1r91 |
T |
A |
7: 19,835,990 (GRCm39) |
V303E |
probably benign |
Het |
| Vmn2r30 |
A |
C |
7: 7,315,334 (GRCm39) |
I833S |
probably damaging |
Het |
| Zfp131 |
G |
T |
13: 120,237,982 (GRCm39) |
N125K |
probably benign |
Het |
| Zfp169 |
A |
T |
13: 48,644,516 (GRCm39) |
|
probably benign |
Het |
| Zfp213 |
C |
A |
17: 23,776,885 (GRCm39) |
E386* |
probably null |
Het |
|
| Other mutations in Phf3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00234:Phf3
|
APN |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00704:Phf3
|
APN |
1 |
30,843,919 (GRCm39) |
missense |
probably benign |
|
|
IGL01147:Phf3
|
APN |
1 |
30,843,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01360:Phf3
|
APN |
1 |
30,847,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01376:Phf3
|
APN |
1 |
30,869,566 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01396:Phf3
|
APN |
1 |
30,843,386 (GRCm39) |
nonsense |
probably null |
|
|
IGL01830:Phf3
|
APN |
1 |
30,853,148 (GRCm39) |
nonsense |
probably null |
|
|
IGL02108:Phf3
|
APN |
1 |
30,869,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02156:Phf3
|
APN |
1 |
30,847,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02576:Phf3
|
APN |
1 |
30,869,117 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03031:Phf3
|
APN |
1 |
30,843,734 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03334:Phf3
|
APN |
1 |
30,844,810 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03411:Phf3
|
APN |
1 |
30,843,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4976:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
utr 3 prime |
probably benign |
|
|
PIT4458001:Phf3
|
UTSW |
1 |
30,855,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0037:Phf3
|
UTSW |
1 |
30,843,999 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0052:Phf3
|
UTSW |
1 |
30,847,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0114:Phf3
|
UTSW |
1 |
30,844,524 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0123:Phf3
|
UTSW |
1 |
30,844,146 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0225:Phf3
|
UTSW |
1 |
30,844,146 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0715:Phf3
|
UTSW |
1 |
30,850,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0835:Phf3
|
UTSW |
1 |
30,869,632 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0848:Phf3
|
UTSW |
1 |
30,902,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Phf3
|
UTSW |
1 |
30,845,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1522:Phf3
|
UTSW |
1 |
30,844,729 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1549:Phf3
|
UTSW |
1 |
30,843,923 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1555:Phf3
|
UTSW |
1 |
30,844,958 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1780:Phf3
|
UTSW |
1 |
30,851,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Phf3
|
UTSW |
1 |
30,845,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Phf3
|
UTSW |
1 |
30,869,704 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1912:Phf3
|
UTSW |
1 |
30,843,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1957:Phf3
|
UTSW |
1 |
30,870,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2019:Phf3
|
UTSW |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2259:Phf3
|
UTSW |
1 |
30,843,424 (GRCm39) |
missense |
probably benign |
0.20 |
|
R2305:Phf3
|
UTSW |
1 |
30,844,556 (GRCm39) |
nonsense |
probably null |
|
|
R2345:Phf3
|
UTSW |
1 |
30,844,432 (GRCm39) |
nonsense |
probably null |
|
|
R2424:Phf3
|
UTSW |
1 |
30,845,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2497:Phf3
|
UTSW |
1 |
30,869,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Phf3
|
UTSW |
1 |
30,849,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3522:Phf3
|
UTSW |
1 |
30,844,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3816:Phf3
|
UTSW |
1 |
30,844,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4152:Phf3
|
UTSW |
1 |
30,870,539 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4403:Phf3
|
UTSW |
1 |
30,843,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4658:Phf3
|
UTSW |
1 |
30,902,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4663:Phf3
|
UTSW |
1 |
30,860,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4669:Phf3
|
UTSW |
1 |
30,869,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4706:Phf3
|
UTSW |
1 |
30,844,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4757:Phf3
|
UTSW |
1 |
30,859,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4766:Phf3
|
UTSW |
1 |
30,853,020 (GRCm39) |
unclassified |
probably benign |
|
|
R4786:Phf3
|
UTSW |
1 |
30,855,638 (GRCm39) |
nonsense |
probably null |
|
|
R5107:Phf3
|
UTSW |
1 |
30,870,566 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5155:Phf3
|
UTSW |
1 |
30,863,457 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R5310:Phf3
|
UTSW |
1 |
30,842,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5823:Phf3
|
UTSW |
1 |
30,843,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5944:Phf3
|
UTSW |
1 |
30,859,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6007:Phf3
|
UTSW |
1 |
30,843,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Phf3
|
UTSW |
1 |
30,902,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6072:Phf3
|
UTSW |
1 |
30,869,769 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6533:Phf3
|
UTSW |
1 |
30,845,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6649:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6653:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6852:Phf3
|
UTSW |
1 |
30,843,711 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6855:Phf3
|
UTSW |
1 |
30,859,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6862:Phf3
|
UTSW |
1 |
30,853,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6930:Phf3
|
UTSW |
1 |
30,850,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7135:Phf3
|
UTSW |
1 |
30,870,190 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7323:Phf3
|
UTSW |
1 |
30,852,211 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7352:Phf3
|
UTSW |
1 |
30,843,407 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7455:Phf3
|
UTSW |
1 |
30,876,239 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7549:Phf3
|
UTSW |
1 |
30,870,556 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7609:Phf3
|
UTSW |
1 |
30,844,582 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7720:Phf3
|
UTSW |
1 |
30,868,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7745:Phf3
|
UTSW |
1 |
30,843,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8134:Phf3
|
UTSW |
1 |
30,863,552 (GRCm39) |
missense |
unknown |
|
|
R8264:Phf3
|
UTSW |
1 |
30,870,138 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8545:Phf3
|
UTSW |
1 |
30,863,391 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8821:Phf3
|
UTSW |
1 |
30,860,347 (GRCm39) |
nonsense |
probably null |
|
|
R8831:Phf3
|
UTSW |
1 |
30,860,347 (GRCm39) |
nonsense |
probably null |
|
|
R8873:Phf3
|
UTSW |
1 |
30,843,773 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R9101:Phf3
|
UTSW |
1 |
30,843,026 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9402:Phf3
|
UTSW |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9426:Phf3
|
UTSW |
1 |
30,870,625 (GRCm39) |
nonsense |
probably null |
|
|
R9594:Phf3
|
UTSW |
1 |
30,869,003 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9707:Phf3
|
UTSW |
1 |
30,868,923 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9803:Phf3
|
UTSW |
1 |
30,869,872 (GRCm39) |
missense |
probably benign |
0.16 |
|
Z1177:Phf3
|
UTSW |
1 |
30,851,049 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Phf3
|
UTSW |
1 |
30,844,132 (GRCm39) |
missense |
unknown |
|
|
Z1177:Phf3
|
UTSW |
1 |
30,843,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCTTTGGAGTATGTCATCCAC -3'
(R):5'- ACCTAATCTGTTGTTGGGCCTG -3'
Sequencing Primer
(F):5'- CATCCACAGGAAGAGGCTTATTTGC -3'
(R):5'- CCTGATTATCCGTCAGAAGCTGAAG -3'
|
| Posted On |
2017-06-26 |
Incidental Mutation