Incidental Mutation 'R5987:Mical2'
| ID |
481733 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| MMRRC Submission |
044167-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.242)
|
| Stock # |
R5987 (G1)
|
| Quality Score |
214.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 111934155 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Methionine
at position 782
(T782M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000047639
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037991]
[ENSMUST00000050149]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000037991
AA Change: T782M
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000047639
Gene: ENSMUSG00000038244
AA Change: T782M
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
3.2e-6 |
PFAM |
|
low complexity region
|
175 |
188 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
low complexity region
|
894 |
925 |
N/A |
INTRINSIC |
|
LIM
|
979 |
1033 |
9.91e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000050149
|
| SMART Domains |
Protein: ENSMUSP00000051163
Gene: ENSMUSG00000038244
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1.1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
1.5e-6 |
PFAM |
|
Pfam:Pyr_redox_2
|
88 |
259 |
1.3e-6 |
PFAM |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
LIM
|
752 |
806 |
9.91e-10 |
SMART |
|
low complexity region
|
918 |
926 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000106648
|
| SMART Domains |
Protein: ENSMUSP00000102259
Gene: ENSMUSG00000038244
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
9.5e-9 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
1.3e-6 |
PFAM |
|
Pfam:Pyr_redox_2
|
88 |
263 |
1e-6 |
PFAM |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
LIM
|
752 |
806 |
1.71e-3 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150428
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.4%
- 10x: 97.2%
- 20x: 91.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca12 |
A |
C |
1: 71,297,257 (GRCm39) |
L2411R |
probably damaging |
Het |
| Als2 |
A |
G |
1: 59,245,746 (GRCm39) |
W577R |
probably damaging |
Het |
| Aox1 |
C |
A |
1: 58,346,518 (GRCm39) |
R551S |
probably benign |
Het |
| Areg |
A |
T |
5: 91,294,577 (GRCm39) |
H245L |
possibly damaging |
Het |
| Arhgap35 |
T |
C |
7: 16,297,392 (GRCm39) |
T558A |
possibly damaging |
Het |
| Arhgef28 |
A |
T |
13: 98,073,368 (GRCm39) |
C1322* |
probably null |
Het |
| Arhgef38 |
T |
C |
3: 132,912,719 (GRCm39) |
R107G |
possibly damaging |
Het |
| Atf7ip |
T |
A |
6: 136,548,500 (GRCm39) |
F695L |
probably damaging |
Het |
| AW209491 |
C |
T |
13: 14,812,365 (GRCm39) |
A406V |
probably benign |
Het |
| Bche |
T |
G |
3: 73,556,011 (GRCm39) |
Q549P |
possibly damaging |
Het |
| Blnk |
A |
G |
19: 40,917,733 (GRCm39) |
F417L |
possibly damaging |
Het |
| Bloc1s1 |
T |
G |
10: 128,759,255 (GRCm39) |
K17T |
probably damaging |
Het |
| C330018D20Rik |
G |
T |
18: 57,090,968 (GRCm39) |
T65K |
probably damaging |
Het |
| Ccdc168 |
A |
T |
1: 44,096,417 (GRCm39) |
N1560K |
probably benign |
Het |
| Cers1 |
T |
A |
8: 70,774,228 (GRCm39) |
S162T |
possibly damaging |
Het |
| Cgn |
T |
C |
3: 94,686,832 (GRCm39) |
K157E |
probably benign |
Het |
| Cldn7 |
G |
A |
11: 69,858,494 (GRCm39) |
R196Q |
probably benign |
Het |
| Clrn2 |
C |
A |
5: 45,611,369 (GRCm39) |
Q73K |
probably benign |
Het |
| Cmss1 |
A |
G |
16: 57,122,608 (GRCm39) |
V262A |
probably benign |
Het |
| Cpb2 |
T |
A |
14: 75,498,128 (GRCm39) |
V97E |
probably damaging |
Het |
| Ctnnd2 |
G |
A |
15: 30,683,387 (GRCm39) |
V463I |
probably benign |
Het |
| Cyp7a1 |
A |
T |
4: 6,268,476 (GRCm39) |
S416R |
probably benign |
Het |
| Dip2b |
C |
T |
15: 100,087,960 (GRCm39) |
R965C |
probably damaging |
Het |
| Dkk3 |
T |
C |
7: 111,749,865 (GRCm39) |
T102A |
probably benign |
Het |
| Dmap1 |
C |
A |
4: 117,538,039 (GRCm39) |
|
probably null |
Het |
| Dnah12 |
C |
A |
14: 26,608,828 (GRCm39) |
D3872E |
possibly damaging |
Het |
| Dnah7b |
A |
G |
1: 46,158,558 (GRCm39) |
|
probably null |
Het |
| Dnai1 |
C |
T |
4: 41,632,391 (GRCm39) |
T575I |
probably benign |
Het |
| Dsg1a |
T |
A |
18: 20,464,599 (GRCm39) |
Y365N |
probably damaging |
Het |
| Dusp11 |
T |
A |
6: 85,936,215 (GRCm39) |
K18* |
probably null |
Het |
| E2f2 |
A |
T |
4: 135,900,245 (GRCm39) |
T52S |
probably benign |
Het |
| Elavl4 |
A |
G |
4: 110,147,841 (GRCm39) |
L13S |
probably benign |
Het |
| Epor |
T |
C |
9: 21,873,572 (GRCm39) |
D59G |
possibly damaging |
Het |
| Eral1 |
A |
G |
11: 77,971,059 (GRCm39) |
C43R |
possibly damaging |
Het |
| Fam135b |
A |
G |
15: 71,362,697 (GRCm39) |
V228A |
probably benign |
Het |
| Gba1 |
T |
C |
3: 89,113,129 (GRCm39) |
S187P |
probably damaging |
Het |
| Gcc2 |
G |
T |
10: 58,091,669 (GRCm39) |
|
probably benign |
Het |
| Gdap2 |
C |
A |
3: 100,109,572 (GRCm39) |
|
probably benign |
Het |
| Gm10271 |
A |
T |
10: 116,808,497 (GRCm39) |
F6L |
probably damaging |
Het |
| Gm10801 |
C |
CGTG |
2: 98,494,152 (GRCm39) |
|
probably null |
Het |
| Gpr160 |
T |
C |
3: 30,950,612 (GRCm39) |
L228P |
probably benign |
Het |
| Gsdmc2 |
A |
C |
15: 63,702,715 (GRCm39) |
V184G |
probably benign |
Het |
| Gtf2e2 |
A |
T |
8: 34,266,080 (GRCm39) |
K252M |
probably damaging |
Het |
| Gtf2e2 |
G |
T |
8: 34,266,081 (GRCm39) |
K252N |
probably benign |
Het |
| Gys1 |
T |
C |
7: 45,087,529 (GRCm39) |
Y102H |
probably benign |
Het |
| H4c2 |
A |
G |
13: 23,941,209 (GRCm39) |
D69G |
probably damaging |
Het |
| Ifit3b |
A |
C |
19: 34,589,598 (GRCm39) |
D258A |
probably damaging |
Het |
| Itpr3 |
T |
A |
17: 27,323,575 (GRCm39) |
M1200K |
probably damaging |
Het |
| Kcng4 |
A |
T |
8: 120,353,098 (GRCm39) |
F271I |
probably damaging |
Het |
| Klhdc2 |
C |
T |
12: 69,350,387 (GRCm39) |
S144L |
possibly damaging |
Het |
| Lhcgr |
A |
G |
17: 89,063,006 (GRCm39) |
F222S |
probably damaging |
Het |
| Lrp5 |
C |
G |
19: 3,678,299 (GRCm39) |
G519R |
probably damaging |
Het |
| Magel2 |
T |
C |
7: 62,028,515 (GRCm39) |
V473A |
probably benign |
Het |
| Map1a |
T |
C |
2: 121,134,776 (GRCm39) |
V1864A |
possibly damaging |
Het |
| Mast4 |
T |
A |
13: 102,895,242 (GRCm39) |
Q760H |
probably damaging |
Het |
| Mertk |
A |
G |
2: 128,613,294 (GRCm39) |
N437D |
probably benign |
Het |
| Mettl18 |
G |
A |
1: 163,824,344 (GRCm39) |
V222I |
probably benign |
Het |
| Mocos |
T |
A |
18: 24,819,750 (GRCm39) |
V664E |
probably damaging |
Het |
| Neb |
G |
T |
2: 52,185,306 (GRCm39) |
N975K |
probably benign |
Het |
| Nectin3 |
A |
T |
16: 46,284,508 (GRCm39) |
S59T |
probably benign |
Het |
| Nelfb |
A |
T |
2: 25,093,900 (GRCm39) |
M11K |
probably damaging |
Het |
| Nrp1 |
A |
G |
8: 129,202,650 (GRCm39) |
N545S |
probably damaging |
Het |
| Or10ak11 |
T |
C |
4: 118,687,478 (GRCm39) |
D53G |
probably damaging |
Het |
| Or2g1 |
T |
A |
17: 38,107,248 (GRCm39) |
N304K |
probably benign |
Het |
| Or51b4 |
T |
A |
7: 103,530,907 (GRCm39) |
D181V |
probably damaging |
Het |
| Or5b117 |
A |
T |
19: 13,431,324 (GRCm39) |
S186T |
possibly damaging |
Het |
| Or5p67 |
T |
A |
7: 107,922,254 (GRCm39) |
T210S |
probably benign |
Het |
| Or6c70 |
A |
T |
10: 129,710,390 (GRCm39) |
F79I |
probably damaging |
Het |
| Or8g53 |
T |
C |
9: 39,683,836 (GRCm39) |
T87A |
probably benign |
Het |
| P3h1 |
A |
G |
4: 119,103,862 (GRCm39) |
H587R |
probably damaging |
Het |
| Paqr4 |
A |
G |
17: 23,958,832 (GRCm39) |
|
probably null |
Het |
| Pde12 |
A |
G |
14: 26,390,253 (GRCm39) |
V152A |
probably benign |
Het |
| Ppip5k1 |
C |
A |
2: 121,180,972 (GRCm39) |
E45* |
probably null |
Het |
| Ptch2 |
C |
T |
4: 116,967,254 (GRCm39) |
A677V |
probably benign |
Het |
| Rgs12 |
A |
G |
5: 35,177,689 (GRCm39) |
N93S |
probably damaging |
Het |
| Rif1 |
C |
G |
2: 51,985,856 (GRCm39) |
L614V |
probably damaging |
Het |
| Rnf32 |
T |
C |
5: 29,408,145 (GRCm39) |
S125P |
probably damaging |
Het |
| Robo4 |
A |
G |
9: 37,322,696 (GRCm39) |
I850V |
probably damaging |
Het |
| Scap |
T |
A |
9: 110,210,219 (GRCm39) |
I876N |
probably damaging |
Het |
| Sin3a |
A |
G |
9: 57,034,484 (GRCm39) |
D1219G |
possibly damaging |
Het |
| Skint5 |
T |
C |
4: 113,743,005 (GRCm39) |
E354G |
unknown |
Het |
| Spart |
A |
G |
3: 55,033,962 (GRCm39) |
D396G |
probably benign |
Het |
| Spindoc |
G |
A |
19: 7,351,024 (GRCm39) |
S311L |
probably benign |
Het |
| Spta1 |
G |
T |
1: 174,050,894 (GRCm39) |
R1791L |
probably damaging |
Het |
| Tbck |
T |
C |
3: 132,507,278 (GRCm39) |
I750T |
possibly damaging |
Het |
| Tmem191 |
T |
C |
16: 17,094,334 (GRCm39) |
|
probably null |
Het |
| Trgv1 |
A |
T |
13: 19,524,474 (GRCm39) |
Y66F |
probably benign |
Het |
| Vmn2r125 |
A |
G |
4: 156,702,292 (GRCm39) |
Y26C |
probably damaging |
Het |
| Zbtb17 |
T |
C |
4: 141,192,128 (GRCm39) |
C358R |
possibly damaging |
Het |
| Zfp180 |
G |
A |
7: 23,804,859 (GRCm39) |
G426E |
probably damaging |
Het |
| Zfp445 |
A |
G |
9: 122,682,951 (GRCm39) |
V330A |
probably benign |
Het |
| Zfp595 |
A |
G |
13: 67,465,688 (GRCm39) |
C192R |
probably damaging |
Het |
| Zkscan4 |
A |
G |
13: 21,668,623 (GRCm39) |
H387R |
probably damaging |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mical2
|
UTSW |
7 |
111,908,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1958:Mical2
|
UTSW |
7 |
111,980,311 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7260:Mical2
|
UTSW |
7 |
111,919,001 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7391:Mical2
|
UTSW |
7 |
111,919,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mical2
|
UTSW |
7 |
111,944,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8830:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9187:Mical2
|
UTSW |
7 |
111,902,797 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9377:Mical2
|
UTSW |
7 |
111,981,246 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9652:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCAGGGTGCTGGAGATACC -3'
(R):5'- CGGTCACCTGAAGCACCTTTTC -3'
Sequencing Primer
(F):5'- GATACCAACACAAGTGTAGAAGTTC -3'
(R):5'- TCTACTTGCTGTAGGCGCCG -3'
|
| Posted On |
2017-06-26 |
Incidental Mutation