Mutagenetix > Incidental Mutation

Incidental Mutation 'R6072:Gm10146'

482544

Institutional Source

Beutler Lab

Gene Symbol

Gm10146

Ensembl Gene

ENSMUSG00000064317

Gene Name

predicted gene 10146

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

R6072 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

78229154-78229462 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

A to G at 78229332 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000072739

SMART Domains

Protein: ENSMUSP00000072521
Gene: ENSMUSG00000064317

Domain	Start	End	E-Value	Type
Sm	13	86	3e-24	SMART

Coding Region Coverage

1x: 99.9%
3x: 99.6%
10x: 98.2%
20x: 94.8%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700093K21Rik	A	T	11: 23,467,357 (GRCm39)	M92K	probably benign	Het
Abca15	T	A	7: 119,987,481 (GRCm39)	C1256S	probably damaging	Het
Asic2	A	G	11: 80,784,914 (GRCm39)	S291P	probably damaging	Het
Asph	A	G	4: 9,643,533 (GRCm39)		probably null	Het
Ccdc57	T	A	11: 120,792,901 (GRCm39)	K284N	probably damaging	Het
Cfap210	A	T	2: 69,602,402 (GRCm39)	D336E	probably benign	Het
Dnm3	CAGCCTTCGTTGGGTG	C	1: 161,838,637 (GRCm39)		probably benign	Het
Dop1a	G	A	9: 86,389,750 (GRCm39)	S558N	probably benign	Het
F830045P16Rik	T	A	2: 129,314,614 (GRCm39)	Q221L	probably damaging	Het
Gys2	T	G	6: 142,374,263 (GRCm39)	D594A	probably damaging	Het
Irf9	A	G	14: 55,843,284 (GRCm39)	E114G	probably damaging	Het
Itpr2	T	G	6: 146,248,609 (GRCm39)	K1082T	probably damaging	Het
Krt14	C	T	11: 100,097,992 (GRCm39)	G97D	unknown	Het
Lmo7	A	T	14: 102,166,772 (GRCm39)		probably benign	Het
Nckap5l	A	T	15: 99,324,535 (GRCm39)	L656Q	probably damaging	Het
Ndufs8	T	C	19: 3,959,275 (GRCm39)	T129A	probably damaging	Het
Nosip	G	A	7: 44,726,072 (GRCm39)	V187M	possibly damaging	Het
Or4l1	A	T	14: 50,166,606 (GRCm39)	Y132N	probably damaging	Het
Or7g18	G	A	9: 18,786,718 (GRCm39)	V29I	probably benign	Het
Phf3	A	C	1: 30,869,769 (GRCm39)	N426K	probably benign	Het
Plekha6	G	C	1: 133,200,045 (GRCm39)	R208P	possibly damaging	Het
Pphln1-ps1	T	C	16: 13,495,353 (GRCm39)	S151P	probably damaging	Het
Ptpru	A	G	4: 131,503,539 (GRCm39)	S1164P	probably damaging	Het
Rcan1	T	C	16: 92,262,815 (GRCm39)	D51G	probably benign	Het
Rem1	A	G	2: 152,476,437 (GRCm39)	T232A	probably benign	Het
Slc1a3	T	A	15: 8,738,052 (GRCm39)	I59F	probably damaging	Het
Slc23a4	T	C	6: 34,925,357 (GRCm39)	K491E	probably benign	Het
Slc6a5	T	A	7: 49,561,943 (GRCm39)	D158E	probably damaging	Het
Smarca4	A	G	9: 21,611,417 (GRCm39)	N1510S	probably damaging	Het
Taf1d	T	C	9: 15,222,856 (GRCm39)	S241P	probably benign	Het
Thada	T	C	17: 84,499,434 (GRCm39)	D1921G	possibly damaging	Het
Tmem147	A	T	7: 30,427,445 (GRCm39)	M99K	possibly damaging	Het
Tulp1	T	C	17: 28,582,758 (GRCm39)	E130G	possibly damaging	Het
Tyw1	T	C	5: 130,296,752 (GRCm39)	V123A	possibly damaging	Het
Wdr75	T	C	1: 45,838,211 (GRCm39)	V40A	probably damaging	Het
Zfp683	T	C	4: 133,783,057 (GRCm39)	Y174H	probably benign	Het

Other mutations in Gm10146

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00089:Gm10146	APN	10	78,229,307 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- TAATTTGGACGTGAGGCGAC -3'
(R):5'- AGTTGACTGGAGCAAGCTGG -3'

Sequencing Primer
(F):5'- CGTGAGGCGACAAGATGGC -3'
(R):5'- CTGGAGTGATCAGAGGTCCTAAATTC -3'

Posted On

2017-07-14