Incidental Mutation 'R6057:Rims2'
| ID |
483004 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rims2
|
| Ensembl Gene |
ENSMUSG00000037386 |
| Gene Name |
regulating synaptic membrane exocytosis 2 |
| Synonyms |
RIM2, 2810036I15Rik, Syt3-rs |
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.539)
|
| Stock # |
R6057 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
15 |
| Chromosomal Location |
39061681-39547768 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 39538416 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Proline
at position 1320
(T1320P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000080711
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042917]
[ENSMUST00000082054]
[ENSMUST00000226410]
[ENSMUST00000227243]
|
| AlphaFold |
Q9EQZ7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000042917
AA Change: T1362P
PolyPhen 2
Score 0.158 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000048719
Gene: ENSMUSG00000037386
AA Change: T1362P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
24 |
N/A |
INTRINSIC |
|
Pfam:FYVE_2
|
30 |
154 |
9.5e-18 |
PFAM |
|
low complexity region
|
315 |
335 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
498 |
N/A |
INTRINSIC |
|
low complexity region
|
511 |
521 |
N/A |
INTRINSIC |
|
low complexity region
|
527 |
540 |
N/A |
INTRINSIC |
|
PDZ
|
646 |
725 |
8.27e-16 |
SMART |
|
low complexity region
|
740 |
748 |
N/A |
INTRINSIC |
|
C2
|
790 |
897 |
4.08e-21 |
SMART |
|
low complexity region
|
905 |
919 |
N/A |
INTRINSIC |
|
low complexity region
|
1085 |
1101 |
N/A |
INTRINSIC |
|
low complexity region
|
1116 |
1130 |
N/A |
INTRINSIC |
|
low complexity region
|
1208 |
1238 |
N/A |
INTRINSIC |
|
C2
|
1432 |
1535 |
3.78e-16 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000082054
AA Change: T1320P
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000080711
Gene: ENSMUSG00000037386
AA Change: T1320P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
24 |
N/A |
INTRINSIC |
|
Pfam:FYVE_2
|
76 |
194 |
2.2e-11 |
PFAM |
|
low complexity region
|
355 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
532 |
538 |
N/A |
INTRINSIC |
|
low complexity region
|
551 |
561 |
N/A |
INTRINSIC |
|
low complexity region
|
567 |
580 |
N/A |
INTRINSIC |
|
PDZ
|
686 |
765 |
8.27e-16 |
SMART |
|
low complexity region
|
780 |
788 |
N/A |
INTRINSIC |
|
C2
|
830 |
937 |
4.08e-21 |
SMART |
|
low complexity region
|
945 |
959 |
N/A |
INTRINSIC |
|
low complexity region
|
1075 |
1086 |
N/A |
INTRINSIC |
|
low complexity region
|
1166 |
1196 |
N/A |
INTRINSIC |
|
C2
|
1390 |
1493 |
3.78e-16 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226410
AA Change: T75P
PolyPhen 2
Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000227243
AA Change: T1340P
PolyPhen 2
Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000227381
AA Change: T1086P
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000227469
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 97.9%
- 20x: 93.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. [provided by RefSeq, Feb 2017]
PHENOTYPE: Mice homozygous for a knock-out allele show reduced body size, aberrant insulin granule exocytosis, and impaired secretion of hormones associated with glucose homeostasis. Mice homozygous for another knock-out allele show a slightly reduced body size, abnormal maternal behavior and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5730596B20Rik |
A |
G |
6: 52,156,500 (GRCm39) |
|
probably benign |
Het |
| Acan |
A |
G |
7: 78,749,530 (GRCm39) |
S11G |
probably null |
Het |
| Ankrd13d |
A |
C |
19: 4,332,256 (GRCm39) |
V56G |
probably damaging |
Het |
| Arl15 |
A |
G |
13: 114,104,151 (GRCm39) |
Y76C |
probably damaging |
Het |
| Aspg |
G |
A |
12: 112,087,432 (GRCm39) |
C296Y |
probably damaging |
Het |
| Astl |
T |
A |
2: 127,187,889 (GRCm39) |
D101E |
probably benign |
Het |
| Bmpr2 |
A |
G |
1: 59,881,977 (GRCm39) |
N202S |
probably benign |
Het |
| Borcs7 |
T |
C |
19: 46,690,003 (GRCm39) |
*106Q |
probably null |
Het |
| Brip1 |
A |
G |
11: 85,955,865 (GRCm39) |
S883P |
possibly damaging |
Het |
| Cacng2 |
A |
T |
15: 78,002,991 (GRCm39) |
L34Q |
probably damaging |
Het |
| Catip |
A |
C |
1: 74,402,077 (GRCm39) |
D84A |
probably damaging |
Het |
| Ccdc162 |
A |
G |
10: 41,510,037 (GRCm39) |
L856S |
possibly damaging |
Het |
| Ccdc38 |
A |
G |
10: 93,417,608 (GRCm39) |
K500E |
probably damaging |
Het |
| Ccser2 |
T |
C |
14: 36,663,122 (GRCm39) |
K21E |
probably damaging |
Het |
| Cd93 |
A |
T |
2: 148,283,439 (GRCm39) |
Y636N |
probably damaging |
Het |
| Cep128 |
A |
T |
12: 91,262,998 (GRCm39) |
N300K |
possibly damaging |
Het |
| Cfap44 |
A |
G |
16: 44,269,460 (GRCm39) |
T1155A |
probably benign |
Het |
| Clec16a |
T |
C |
16: 10,447,951 (GRCm39) |
L550P |
probably damaging |
Het |
| Csmd3 |
T |
C |
15: 47,618,787 (GRCm39) |
Y1867C |
probably damaging |
Het |
| Cul3 |
A |
T |
1: 80,249,249 (GRCm39) |
I674N |
probably damaging |
Het |
| Cybb |
C |
G |
X: 9,316,989 (GRCm39) |
D246H |
probably benign |
Het |
| Cyp2d34 |
T |
C |
15: 82,500,552 (GRCm39) |
H429R |
probably benign |
Het |
| Dab2ip |
T |
A |
2: 35,582,267 (GRCm39) |
C4* |
probably null |
Het |
| Dcaf1 |
A |
G |
9: 106,731,446 (GRCm39) |
E641G |
probably damaging |
Het |
| Dda1 |
T |
A |
8: 71,927,276 (GRCm39) |
|
probably benign |
Het |
| Dmgdh |
C |
T |
13: 93,888,960 (GRCm39) |
T866I |
probably benign |
Het |
| Ect2l |
T |
C |
10: 18,037,250 (GRCm39) |
T383A |
probably benign |
Het |
| Ets2 |
A |
G |
16: 95,515,416 (GRCm39) |
N181D |
probably benign |
Het |
| Ezh2 |
A |
G |
6: 47,529,357 (GRCm39) |
F222L |
probably damaging |
Het |
| Frem3 |
T |
C |
8: 81,342,216 (GRCm39) |
L1503P |
probably damaging |
Het |
| Fsip2 |
C |
A |
2: 82,809,777 (GRCm39) |
A2032E |
probably damaging |
Het |
| Gm1818 |
C |
T |
12: 48,602,346 (GRCm39) |
|
noncoding transcript |
Het |
| Gm9493 |
A |
G |
19: 23,597,106 (GRCm39) |
S1G |
probably damaging |
Het |
| Grin2b |
A |
G |
6: 135,710,942 (GRCm39) |
I868T |
possibly damaging |
Het |
| Ift22 |
A |
T |
5: 136,939,987 (GRCm39) |
T17S |
possibly damaging |
Het |
| Il4ra |
T |
C |
7: 125,170,735 (GRCm39) |
W216R |
probably damaging |
Het |
| Kcnj6 |
A |
T |
16: 94,633,236 (GRCm39) |
W274R |
probably damaging |
Het |
| Kctd19 |
G |
A |
8: 106,123,082 (GRCm39) |
H111Y |
probably damaging |
Het |
| Kremen2 |
A |
G |
17: 23,961,679 (GRCm39) |
V276A |
probably benign |
Het |
| Lig1 |
C |
A |
7: 13,022,598 (GRCm39) |
Q143K |
probably damaging |
Het |
| Lrp1 |
A |
T |
10: 127,403,359 (GRCm39) |
D2071E |
probably damaging |
Het |
| Macf1 |
C |
T |
4: 123,404,536 (GRCm39) |
M475I |
probably damaging |
Het |
| Mbtd1 |
G |
A |
11: 93,820,485 (GRCm39) |
A427T |
probably damaging |
Het |
| Myof |
A |
G |
19: 37,915,429 (GRCm39) |
|
probably null |
Het |
| Nbeal2 |
T |
C |
9: 110,470,945 (GRCm39) |
D308G |
possibly damaging |
Het |
| Ncdn |
T |
C |
4: 126,638,824 (GRCm39) |
Q665R |
probably benign |
Het |
| Nkd1 |
T |
C |
8: 89,316,442 (GRCm39) |
|
probably null |
Het |
| Nktr |
G |
A |
9: 121,577,455 (GRCm39) |
|
probably benign |
Het |
| Npc1l1 |
A |
T |
11: 6,167,806 (GRCm39) |
M995K |
possibly damaging |
Het |
| Or10ag59 |
C |
A |
2: 87,406,363 (GRCm39) |
R312S |
probably benign |
Het |
| Or11g7 |
A |
T |
14: 50,691,201 (GRCm39) |
R231* |
probably null |
Het |
| Or14n1-ps1 |
T |
A |
7: 86,092,397 (GRCm39) |
C69* |
probably null |
Het |
| Padi4 |
T |
C |
4: 140,487,351 (GRCm39) |
T184A |
probably damaging |
Het |
| Pgm2l1 |
C |
T |
7: 99,915,881 (GRCm39) |
P409S |
probably benign |
Het |
| Pgpep1 |
G |
A |
8: 71,105,101 (GRCm39) |
T53M |
probably damaging |
Het |
| Pgr |
T |
C |
9: 8,902,006 (GRCm39) |
L513P |
probably damaging |
Het |
| Pikfyve |
T |
A |
1: 65,311,730 (GRCm39) |
I1989N |
probably damaging |
Het |
| Prrc2a |
T |
C |
17: 35,371,716 (GRCm39) |
T1806A |
probably benign |
Het |
| Psd |
T |
C |
19: 46,311,753 (GRCm39) |
E309G |
possibly damaging |
Het |
| Qtrt1 |
C |
T |
9: 21,323,299 (GRCm39) |
T50I |
probably damaging |
Het |
| Scn11a |
T |
G |
9: 119,594,514 (GRCm39) |
N1293T |
probably damaging |
Het |
| Scn8a |
T |
C |
15: 100,872,548 (GRCm39) |
F529S |
possibly damaging |
Het |
| Sec14l4 |
A |
T |
11: 3,985,142 (GRCm39) |
D25V |
possibly damaging |
Het |
| Sema3a |
C |
T |
5: 13,615,832 (GRCm39) |
R419C |
probably damaging |
Het |
| Slc12a1 |
T |
C |
2: 125,032,133 (GRCm39) |
Y595H |
probably damaging |
Het |
| Slc25a28 |
A |
T |
19: 43,655,364 (GRCm39) |
H170Q |
possibly damaging |
Het |
| Slc26a1 |
T |
A |
5: 108,821,631 (GRCm39) |
Q86L |
probably damaging |
Het |
| Slc48a1 |
T |
A |
15: 97,687,798 (GRCm39) |
W51R |
probably damaging |
Het |
| Sptlc3 |
T |
A |
2: 139,423,533 (GRCm39) |
V309D |
probably damaging |
Het |
| Srcap |
G |
A |
7: 127,140,528 (GRCm39) |
S1375N |
probably damaging |
Het |
| Tanc1 |
C |
A |
2: 59,647,837 (GRCm39) |
H986Q |
possibly damaging |
Het |
| Tbc1d4 |
A |
G |
14: 101,727,353 (GRCm39) |
V486A |
probably damaging |
Het |
| Tceanc2 |
T |
C |
4: 107,004,776 (GRCm39) |
D124G |
probably damaging |
Het |
| Tdrd9 |
A |
G |
12: 111,979,720 (GRCm39) |
M402V |
possibly damaging |
Het |
| Tmem132d |
T |
C |
5: 127,861,934 (GRCm39) |
D729G |
probably damaging |
Het |
| Tmem62 |
T |
A |
2: 120,807,943 (GRCm39) |
I55N |
probably damaging |
Het |
| Tnfrsf21 |
A |
T |
17: 43,350,606 (GRCm39) |
N257Y |
possibly damaging |
Het |
| Trappc3 |
T |
C |
4: 126,167,834 (GRCm39) |
L131P |
probably damaging |
Het |
| Vmn2r25 |
A |
T |
6: 123,799,900 (GRCm39) |
M814K |
possibly damaging |
Het |
| Vmn2r87 |
T |
C |
10: 130,308,226 (GRCm39) |
I671V |
probably benign |
Het |
| Vwa8 |
A |
T |
14: 79,320,313 (GRCm39) |
D1108V |
probably benign |
Het |
| Xrcc4 |
C |
G |
13: 90,139,198 (GRCm39) |
A241P |
possibly damaging |
Het |
| Xylt1 |
T |
A |
7: 117,191,135 (GRCm39) |
D310E |
probably benign |
Het |
| Zfp27 |
T |
G |
7: 29,594,444 (GRCm39) |
H507P |
possibly damaging |
Het |
| Zfp341 |
C |
T |
2: 154,466,954 (GRCm39) |
P108S |
probably benign |
Het |
| Zfp641 |
T |
C |
15: 98,190,816 (GRCm39) |
N76S |
probably benign |
Het |
| Zfp936 |
T |
C |
7: 42,839,787 (GRCm39) |
V418A |
probably benign |
Het |
|
| Other mutations in Rims2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00339:Rims2
|
APN |
15 |
39,323,011 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL00502:Rims2
|
APN |
15 |
39,370,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00556:Rims2
|
APN |
15 |
39,320,070 (GRCm39) |
splice site |
probably null |
|
|
IGL00811:Rims2
|
APN |
15 |
39,155,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00827:Rims2
|
APN |
15 |
39,335,755 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01642:Rims2
|
APN |
15 |
39,321,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Rims2
|
APN |
15 |
39,398,334 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03009:Rims2
|
APN |
15 |
39,430,393 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL03080:Rims2
|
APN |
15 |
39,399,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Rims2
|
APN |
15 |
39,322,989 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03252:Rims2
|
APN |
15 |
39,315,748 (GRCm39) |
missense |
probably benign |
|
|
IGL03365:Rims2
|
APN |
15 |
39,339,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03393:Rims2
|
APN |
15 |
39,326,009 (GRCm39) |
splice site |
probably null |
|
|
IGL03409:Rims2
|
APN |
15 |
39,320,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
rhyme
|
UTSW |
15 |
39,315,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4486001:Rims2
|
UTSW |
15 |
39,339,916 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0009:Rims2
|
UTSW |
15 |
39,398,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0009:Rims2
|
UTSW |
15 |
39,398,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0078:Rims2
|
UTSW |
15 |
39,398,251 (GRCm39) |
missense |
probably benign |
0.42 |
|
R0367:Rims2
|
UTSW |
15 |
39,326,011 (GRCm39) |
splice site |
probably null |
|
|
R0401:Rims2
|
UTSW |
15 |
39,373,028 (GRCm39) |
splice site |
probably benign |
|
|
R0531:Rims2
|
UTSW |
15 |
39,430,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0791:Rims2
|
UTSW |
15 |
39,543,021 (GRCm39) |
splice site |
probably benign |
|
|
R0838:Rims2
|
UTSW |
15 |
39,544,421 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1201:Rims2
|
UTSW |
15 |
39,479,720 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1318:Rims2
|
UTSW |
15 |
39,381,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1457:Rims2
|
UTSW |
15 |
39,374,710 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1619:Rims2
|
UTSW |
15 |
39,370,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1672:Rims2
|
UTSW |
15 |
39,155,584 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1743:Rims2
|
UTSW |
15 |
39,543,046 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1766:Rims2
|
UTSW |
15 |
39,325,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1779:Rims2
|
UTSW |
15 |
39,545,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1804:Rims2
|
UTSW |
15 |
39,300,439 (GRCm39) |
nonsense |
probably null |
|
|
R1985:Rims2
|
UTSW |
15 |
39,208,710 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1986:Rims2
|
UTSW |
15 |
39,208,710 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2113:Rims2
|
UTSW |
15 |
39,374,722 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2260:Rims2
|
UTSW |
15 |
39,341,962 (GRCm39) |
nonsense |
probably null |
|
|
R2510:Rims2
|
UTSW |
15 |
39,449,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3693:Rims2
|
UTSW |
15 |
39,341,971 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3937:Rims2
|
UTSW |
15 |
39,301,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4425:Rims2
|
UTSW |
15 |
39,301,320 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4453:Rims2
|
UTSW |
15 |
39,155,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4474:Rims2
|
UTSW |
15 |
39,325,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4518:Rims2
|
UTSW |
15 |
39,300,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4526:Rims2
|
UTSW |
15 |
39,301,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4833:Rims2
|
UTSW |
15 |
39,399,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4936:Rims2
|
UTSW |
15 |
39,301,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4993:Rims2
|
UTSW |
15 |
39,317,841 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5001:Rims2
|
UTSW |
15 |
39,315,824 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5054:Rims2
|
UTSW |
15 |
39,381,265 (GRCm39) |
splice site |
probably null |
|
|
R5072:Rims2
|
UTSW |
15 |
39,325,986 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5171:Rims2
|
UTSW |
15 |
39,300,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5429:Rims2
|
UTSW |
15 |
39,208,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5623:Rims2
|
UTSW |
15 |
39,342,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5624:Rims2
|
UTSW |
15 |
39,208,809 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5685:Rims2
|
UTSW |
15 |
39,300,602 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5784:Rims2
|
UTSW |
15 |
39,399,383 (GRCm39) |
splice site |
probably null |
|
|
R5790:Rims2
|
UTSW |
15 |
39,544,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5822:Rims2
|
UTSW |
15 |
39,339,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5963:Rims2
|
UTSW |
15 |
39,300,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Rims2
|
UTSW |
15 |
39,155,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Rims2
|
UTSW |
15 |
39,061,758 (GRCm39) |
start codon destroyed |
unknown |
|
|
R6407:Rims2
|
UTSW |
15 |
39,315,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6418:Rims2
|
UTSW |
15 |
39,373,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6495:Rims2
|
UTSW |
15 |
39,381,208 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6502:Rims2
|
UTSW |
15 |
39,398,251 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6753:Rims2
|
UTSW |
15 |
39,430,369 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6855:Rims2
|
UTSW |
15 |
39,208,911 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6948:Rims2
|
UTSW |
15 |
39,374,737 (GRCm39) |
missense |
probably benign |
|
|
R7058:Rims2
|
UTSW |
15 |
39,449,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Rims2
|
UTSW |
15 |
39,300,473 (GRCm39) |
missense |
probably benign |
|
|
R7217:Rims2
|
UTSW |
15 |
39,339,885 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7223:Rims2
|
UTSW |
15 |
39,300,428 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7289:Rims2
|
UTSW |
15 |
39,301,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7459:Rims2
|
UTSW |
15 |
39,381,235 (GRCm39) |
missense |
probably benign |
|
|
R7663:Rims2
|
UTSW |
15 |
39,370,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7792:Rims2
|
UTSW |
15 |
39,061,923 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7836:Rims2
|
UTSW |
15 |
39,544,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8082:Rims2
|
UTSW |
15 |
39,339,919 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8489:Rims2
|
UTSW |
15 |
39,479,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8730:Rims2
|
UTSW |
15 |
39,381,239 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8830:Rims2
|
UTSW |
15 |
39,300,758 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R8857:Rims2
|
UTSW |
15 |
39,543,044 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8893:Rims2
|
UTSW |
15 |
39,398,350 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9010:Rims2
|
UTSW |
15 |
39,315,786 (GRCm39) |
nonsense |
probably null |
|
|
R9030:Rims2
|
UTSW |
15 |
39,339,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9287:Rims2
|
UTSW |
15 |
39,543,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9395:Rims2
|
UTSW |
15 |
39,155,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9451:Rims2
|
UTSW |
15 |
39,300,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9506:Rims2
|
UTSW |
15 |
39,335,832 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0034:Rims2
|
UTSW |
15 |
39,300,930 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Rims2
|
UTSW |
15 |
39,544,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Rims2
|
UTSW |
15 |
39,342,086 (GRCm39) |
frame shift |
probably null |
|
|
Z1177:Rims2
|
UTSW |
15 |
39,301,165 (GRCm39) |
missense |
probably benign |
0.24 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAAGAACACAGCGGGTCTGC -3'
(R):5'- TGAGCAGTGTGAGTTAGCACTG -3'
|
| Posted On |
2017-07-14 |
Incidental Mutation