Incidental Mutation 'R6180:Ltn1'
| ID |
488038 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ltn1
|
| Ensembl Gene |
ENSMUSG00000052299 |
| Gene Name |
listerin E3 ubiquitin protein ligase 1 |
| Synonyms |
Listerin, Zfp294, Rnf160, 4930528H02Rik |
| MMRRC Submission |
044322-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R6180 (G1)
|
| Quality Score |
211.009 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
87173539-87229500 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 87224677 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 16
(S16T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156299
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039449]
[ENSMUST00000232095]
|
| AlphaFold |
Q6A009 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039449
AA Change: S16T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000038775
Gene: ENSMUSG00000052299
AA Change: S16T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
160 |
176 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
410 |
N/A |
INTRINSIC |
|
low complexity region
|
509 |
522 |
N/A |
INTRINSIC |
|
low complexity region
|
553 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
832 |
N/A |
INTRINSIC |
|
low complexity region
|
1380 |
1392 |
N/A |
INTRINSIC |
|
low complexity region
|
1427 |
1451 |
N/A |
INTRINSIC |
|
RING
|
1716 |
1762 |
1.05e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000232095
AA Change: S16T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.1%
- 20x: 94.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 [PubMed 19196968]).[supplied by OMIM, Nov 2010]
PHENOTYPE: Mice homozygous for a gene trap allele display embryonic lethality. Mice homozygous for a point mutation display progressive neuron degeneration and age dependent motor deficits. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam39 |
A |
G |
8: 41,279,610 (GRCm39) |
N667S |
probably benign |
Het |
| Ap4e1 |
T |
A |
2: 126,908,508 (GRCm39) |
C1085* |
probably null |
Het |
| BC035044 |
A |
T |
6: 128,861,997 (GRCm39) |
|
probably benign |
Het |
| Bltp2 |
A |
G |
11: 78,164,084 (GRCm39) |
M1142V |
possibly damaging |
Het |
| Capn11 |
T |
C |
17: 45,941,692 (GRCm39) |
D693G |
probably damaging |
Het |
| Cavin4 |
A |
T |
4: 48,663,917 (GRCm39) |
H99L |
possibly damaging |
Het |
| Ccdc86 |
T |
C |
19: 10,925,945 (GRCm39) |
K218R |
possibly damaging |
Het |
| Ccno |
T |
C |
13: 113,126,379 (GRCm39) |
S283P |
probably damaging |
Het |
| Ccser2 |
A |
T |
14: 36,662,276 (GRCm39) |
S303T |
probably benign |
Het |
| Cd53 |
T |
A |
3: 106,674,680 (GRCm39) |
N129I |
probably damaging |
Het |
| Cd63 |
G |
A |
10: 128,747,933 (GRCm39) |
|
probably null |
Het |
| Cyp2j6 |
G |
C |
4: 96,424,323 (GRCm39) |
L145V |
probably damaging |
Het |
| Daam2 |
A |
G |
17: 49,776,694 (GRCm39) |
M797T |
probably damaging |
Het |
| Dennd2b |
A |
C |
7: 109,156,095 (GRCm39) |
D218E |
probably benign |
Het |
| Dmgdh |
G |
A |
13: 93,888,794 (GRCm39) |
V811I |
possibly damaging |
Het |
| Dpysl4 |
A |
T |
7: 138,670,250 (GRCm39) |
T123S |
probably damaging |
Het |
| Erap1 |
A |
G |
13: 74,814,345 (GRCm39) |
E428G |
possibly damaging |
Het |
| Fam124b |
T |
A |
1: 80,177,902 (GRCm39) |
T366S |
possibly damaging |
Het |
| Fbxw22 |
T |
C |
9: 109,215,747 (GRCm39) |
D167G |
probably damaging |
Het |
| Flrt2 |
C |
T |
12: 95,746,012 (GRCm39) |
Q117* |
probably null |
Het |
| Ftsj3 |
A |
T |
11: 106,144,166 (GRCm39) |
|
probably null |
Het |
| Ggn |
A |
G |
7: 28,872,474 (GRCm39) |
Y618C |
probably damaging |
Het |
| Glis1 |
T |
A |
4: 107,484,710 (GRCm39) |
S402T |
probably benign |
Het |
| Gm4781 |
T |
A |
10: 100,232,349 (GRCm39) |
|
noncoding transcript |
Het |
| Gm7168 |
T |
A |
17: 14,168,858 (GRCm39) |
I75K |
probably damaging |
Het |
| Gm7298 |
C |
T |
6: 121,737,782 (GRCm39) |
H348Y |
probably benign |
Het |
| Gria1 |
G |
T |
11: 57,133,618 (GRCm39) |
R499L |
probably damaging |
Het |
| Gtf2ird2 |
C |
T |
5: 134,245,389 (GRCm39) |
T549M |
probably damaging |
Het |
| H2-M10.6 |
T |
A |
17: 37,125,178 (GRCm39) |
V323E |
probably damaging |
Het |
| Hoxb3 |
G |
A |
11: 96,236,929 (GRCm39) |
V336I |
probably benign |
Het |
| Il12b |
G |
A |
11: 44,303,453 (GRCm39) |
A327T |
probably benign |
Het |
| Inpp4a |
C |
A |
1: 37,419,183 (GRCm39) |
P588T |
probably benign |
Het |
| Kctd12 |
C |
A |
14: 103,219,027 (GRCm39) |
D284Y |
probably damaging |
Het |
| Kif28 |
C |
A |
1: 179,525,337 (GRCm39) |
|
probably null |
Het |
| Krt1c |
T |
C |
15: 101,723,479 (GRCm39) |
N332S |
probably benign |
Het |
| Lama2 |
G |
A |
10: 26,857,495 (GRCm39) |
T3118I |
probably benign |
Het |
| Lgi1 |
T |
C |
19: 38,253,404 (GRCm39) |
L25P |
probably damaging |
Het |
| Lhx3 |
T |
A |
2: 26,091,503 (GRCm39) |
M269L |
probably benign |
Het |
| Lmtk2 |
A |
T |
5: 144,112,160 (GRCm39) |
E960V |
probably damaging |
Het |
| Loxl4 |
A |
T |
19: 42,596,791 (GRCm39) |
D60E |
probably damaging |
Het |
| Lrp2 |
T |
A |
2: 69,333,868 (GRCm39) |
N1458Y |
possibly damaging |
Het |
| Mllt6 |
G |
A |
11: 97,569,362 (GRCm39) |
A875T |
possibly damaging |
Het |
| Mrgprb4 |
A |
T |
7: 47,848,574 (GRCm39) |
I118N |
probably damaging |
Het |
| Mrps7 |
A |
G |
11: 115,495,707 (GRCm39) |
T82A |
possibly damaging |
Het |
| Mug2 |
A |
G |
6: 122,056,565 (GRCm39) |
E1170G |
probably benign |
Het |
| Nav2 |
A |
G |
7: 49,107,915 (GRCm39) |
H647R |
probably benign |
Het |
| Nbeal2 |
T |
C |
9: 110,454,215 (GRCm39) |
Y2710C |
probably damaging |
Het |
| Ndc1 |
A |
T |
4: 107,268,395 (GRCm39) |
I644L |
possibly damaging |
Het |
| Or4c108 |
T |
G |
2: 88,804,226 (GRCm39) |
N3T |
probably damaging |
Het |
| Or8g33 |
A |
T |
9: 39,338,008 (GRCm39) |
Y120N |
probably damaging |
Het |
| Padi4 |
A |
G |
4: 140,483,784 (GRCm39) |
M352T |
possibly damaging |
Het |
| Pals1 |
C |
T |
12: 78,864,084 (GRCm39) |
H216Y |
probably benign |
Het |
| Pcdhgc3 |
C |
A |
18: 37,939,990 (GRCm39) |
D130E |
probably damaging |
Het |
| Pde6a |
A |
T |
18: 61,417,163 (GRCm39) |
|
probably null |
Het |
| Pdpn |
C |
T |
4: 143,025,792 (GRCm39) |
G12R |
probably damaging |
Het |
| Pot1a |
A |
T |
6: 25,771,620 (GRCm39) |
D200E |
probably benign |
Het |
| Ppa1 |
A |
T |
10: 61,503,431 (GRCm39) |
D236V |
probably benign |
Het |
| Ptprn2 |
T |
A |
12: 116,822,739 (GRCm39) |
S273T |
probably benign |
Het |
| Rasgrf2 |
T |
C |
13: 92,165,609 (GRCm39) |
E297G |
probably damaging |
Het |
| Rgl1 |
T |
C |
1: 152,394,923 (GRCm39) |
N750S |
probably damaging |
Het |
| Rinl |
A |
G |
7: 28,496,365 (GRCm39) |
N449D |
probably benign |
Het |
| Samd8 |
T |
A |
14: 21,825,093 (GRCm39) |
H79Q |
probably benign |
Het |
| Scn11a |
T |
C |
9: 119,583,933 (GRCm39) |
I1561V |
probably benign |
Het |
| Slc39a12 |
T |
C |
2: 14,400,938 (GRCm39) |
L105P |
probably benign |
Het |
| Slc7a12 |
A |
T |
3: 14,546,200 (GRCm39) |
|
probably null |
Het |
| Slco1a4 |
A |
G |
6: 141,763,546 (GRCm39) |
I390T |
possibly damaging |
Het |
| Snta1 |
T |
C |
2: 154,219,102 (GRCm39) |
N411S |
probably benign |
Het |
| Srgap2 |
T |
C |
1: 131,277,279 (GRCm39) |
T323A |
probably benign |
Het |
| Ssh2 |
G |
T |
11: 77,344,291 (GRCm39) |
V759L |
probably benign |
Het |
| Swap70 |
G |
T |
7: 109,869,188 (GRCm39) |
R327L |
probably damaging |
Het |
| Tbc1d4 |
C |
A |
14: 101,696,206 (GRCm39) |
C914F |
probably benign |
Het |
| Tbx3 |
A |
G |
5: 119,812,132 (GRCm39) |
D144G |
probably damaging |
Het |
| Tgfbr2 |
T |
C |
9: 115,939,212 (GRCm39) |
K205R |
possibly damaging |
Het |
| Tmem94 |
A |
T |
11: 115,681,857 (GRCm39) |
|
probably null |
Het |
| Usf3 |
T |
A |
16: 44,041,468 (GRCm39) |
F1983I |
probably damaging |
Het |
| Ush2a |
T |
A |
1: 188,132,068 (GRCm39) |
C763* |
probably null |
Het |
| Vmn1r115 |
A |
C |
7: 20,578,640 (GRCm39) |
L91V |
probably damaging |
Het |
| Vmn1r201 |
A |
T |
13: 22,659,499 (GRCm39) |
I238F |
possibly damaging |
Het |
| Vmn1r28 |
T |
A |
6: 58,242,476 (GRCm39) |
S106R |
probably damaging |
Het |
| Vmn1r82 |
T |
C |
7: 12,039,012 (GRCm39) |
V95A |
probably damaging |
Het |
| Vrk3 |
A |
T |
7: 44,419,035 (GRCm39) |
N371I |
possibly damaging |
Het |
| Wnt8b |
C |
A |
19: 44,500,082 (GRCm39) |
A223E |
probably benign |
Het |
| Xirp2 |
T |
C |
2: 67,335,921 (GRCm39) |
|
probably null |
Het |
| Xpo7 |
T |
C |
14: 70,920,243 (GRCm39) |
N642S |
probably benign |
Het |
| Ythdc1 |
G |
A |
5: 86,975,953 (GRCm39) |
R520H |
possibly damaging |
Het |
| Zfp367 |
T |
C |
13: 64,283,204 (GRCm39) |
E316G |
probably damaging |
Het |
| Zfp488 |
T |
A |
14: 33,692,751 (GRCm39) |
R137S |
possibly damaging |
Het |
| Zfp532 |
G |
T |
18: 65,789,542 (GRCm39) |
V994L |
probably benign |
Het |
|
| Other mutations in Ltn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00328:Ltn1
|
APN |
16 |
87,215,378 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01139:Ltn1
|
APN |
16 |
87,212,897 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01359:Ltn1
|
APN |
16 |
87,202,581 (GRCm39) |
splice site |
probably benign |
|
|
IGL01503:Ltn1
|
APN |
16 |
87,217,695 (GRCm39) |
critical splice donor site |
probably benign |
|
|
IGL01529:Ltn1
|
APN |
16 |
87,178,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02437:Ltn1
|
APN |
16 |
87,194,889 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02658:Ltn1
|
APN |
16 |
87,212,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02890:Ltn1
|
APN |
16 |
87,206,185 (GRCm39) |
splice site |
probably null |
|
|
IGL02899:Ltn1
|
APN |
16 |
87,179,547 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02902:Ltn1
|
APN |
16 |
87,176,693 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL03128:Ltn1
|
APN |
16 |
87,212,832 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03392:Ltn1
|
APN |
16 |
87,222,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03046:Ltn1
|
UTSW |
16 |
87,202,509 (GRCm39) |
missense |
probably benign |
0.10 |
|
PIT4305001:Ltn1
|
UTSW |
16 |
87,217,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4366001:Ltn1
|
UTSW |
16 |
87,177,728 (GRCm39) |
nonsense |
probably null |
|
|
R0126:Ltn1
|
UTSW |
16 |
87,222,528 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0164:Ltn1
|
UTSW |
16 |
87,202,407 (GRCm39) |
splice site |
probably benign |
|
|
R0165:Ltn1
|
UTSW |
16 |
87,202,407 (GRCm39) |
splice site |
probably benign |
|
|
R0280:Ltn1
|
UTSW |
16 |
87,194,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0565:Ltn1
|
UTSW |
16 |
87,212,898 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0733:Ltn1
|
UTSW |
16 |
87,209,395 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1034:Ltn1
|
UTSW |
16 |
87,194,025 (GRCm39) |
splice site |
probably null |
|
|
R1252:Ltn1
|
UTSW |
16 |
87,212,918 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1524:Ltn1
|
UTSW |
16 |
87,178,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1746:Ltn1
|
UTSW |
16 |
87,208,669 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1826:Ltn1
|
UTSW |
16 |
87,212,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1831:Ltn1
|
UTSW |
16 |
87,197,034 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1839:Ltn1
|
UTSW |
16 |
87,213,152 (GRCm39) |
nonsense |
probably null |
|
|
R1860:Ltn1
|
UTSW |
16 |
87,213,231 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1997:Ltn1
|
UTSW |
16 |
87,178,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2109:Ltn1
|
UTSW |
16 |
87,212,530 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2134:Ltn1
|
UTSW |
16 |
87,179,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2135:Ltn1
|
UTSW |
16 |
87,179,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2193:Ltn1
|
UTSW |
16 |
87,224,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2307:Ltn1
|
UTSW |
16 |
87,229,312 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2376:Ltn1
|
UTSW |
16 |
87,217,695 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3054:Ltn1
|
UTSW |
16 |
87,200,961 (GRCm39) |
missense |
probably benign |
0.32 |
|
R3404:Ltn1
|
UTSW |
16 |
87,213,103 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3405:Ltn1
|
UTSW |
16 |
87,213,103 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3618:Ltn1
|
UTSW |
16 |
87,217,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4065:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4066:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4067:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4288:Ltn1
|
UTSW |
16 |
87,194,876 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4436:Ltn1
|
UTSW |
16 |
87,202,502 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4535:Ltn1
|
UTSW |
16 |
87,223,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4581:Ltn1
|
UTSW |
16 |
87,198,912 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4669:Ltn1
|
UTSW |
16 |
87,215,375 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4715:Ltn1
|
UTSW |
16 |
87,215,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4830:Ltn1
|
UTSW |
16 |
87,176,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Ltn1
|
UTSW |
16 |
87,195,697 (GRCm39) |
nonsense |
probably null |
|
|
R4961:Ltn1
|
UTSW |
16 |
87,194,679 (GRCm39) |
missense |
probably benign |
|
|
R4992:Ltn1
|
UTSW |
16 |
87,202,475 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R5073:Ltn1
|
UTSW |
16 |
87,224,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5288:Ltn1
|
UTSW |
16 |
87,212,899 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5802:Ltn1
|
UTSW |
16 |
87,212,569 (GRCm39) |
missense |
probably benign |
0.17 |
|
R5907:Ltn1
|
UTSW |
16 |
87,178,391 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6194:Ltn1
|
UTSW |
16 |
87,212,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6257:Ltn1
|
UTSW |
16 |
87,208,662 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6301:Ltn1
|
UTSW |
16 |
87,217,194 (GRCm39) |
missense |
probably benign |
|
|
R6481:Ltn1
|
UTSW |
16 |
87,175,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6525:Ltn1
|
UTSW |
16 |
87,217,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6958:Ltn1
|
UTSW |
16 |
87,194,679 (GRCm39) |
missense |
probably benign |
|
|
R6969:Ltn1
|
UTSW |
16 |
87,212,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7002:Ltn1
|
UTSW |
16 |
87,220,361 (GRCm39) |
missense |
probably benign |
|
|
R7038:Ltn1
|
UTSW |
16 |
87,221,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7062:Ltn1
|
UTSW |
16 |
87,224,491 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7152:Ltn1
|
UTSW |
16 |
87,224,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Ltn1
|
UTSW |
16 |
87,215,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7247:Ltn1
|
UTSW |
16 |
87,206,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7454:Ltn1
|
UTSW |
16 |
87,194,700 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7471:Ltn1
|
UTSW |
16 |
87,194,787 (GRCm39) |
missense |
probably benign |
|
|
R7511:Ltn1
|
UTSW |
16 |
87,205,716 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7691:Ltn1
|
UTSW |
16 |
87,195,574 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7702:Ltn1
|
UTSW |
16 |
87,223,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7761:Ltn1
|
UTSW |
16 |
87,208,681 (GRCm39) |
missense |
probably benign |
|
|
R8002:Ltn1
|
UTSW |
16 |
87,212,835 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8101:Ltn1
|
UTSW |
16 |
87,215,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8142:Ltn1
|
UTSW |
16 |
87,178,529 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8214:Ltn1
|
UTSW |
16 |
87,177,691 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8674:Ltn1
|
UTSW |
16 |
87,195,673 (GRCm39) |
missense |
probably benign |
|
|
R8783:Ltn1
|
UTSW |
16 |
87,207,247 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8839:Ltn1
|
UTSW |
16 |
87,215,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8885:Ltn1
|
UTSW |
16 |
87,178,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8889:Ltn1
|
UTSW |
16 |
87,229,230 (GRCm39) |
intron |
probably benign |
|
|
R8892:Ltn1
|
UTSW |
16 |
87,229,230 (GRCm39) |
intron |
probably benign |
|
|
R8919:Ltn1
|
UTSW |
16 |
87,178,381 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8970:Ltn1
|
UTSW |
16 |
87,212,926 (GRCm39) |
missense |
probably benign |
|
|
R9113:Ltn1
|
UTSW |
16 |
87,224,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9206:Ltn1
|
UTSW |
16 |
87,197,298 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9208:Ltn1
|
UTSW |
16 |
87,197,298 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9234:Ltn1
|
UTSW |
16 |
87,194,089 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9421:Ltn1
|
UTSW |
16 |
87,215,375 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9558:Ltn1
|
UTSW |
16 |
87,220,295 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9654:Ltn1
|
UTSW |
16 |
87,207,227 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9738:Ltn1
|
UTSW |
16 |
87,222,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0028:Ltn1
|
UTSW |
16 |
87,199,022 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Ltn1
|
UTSW |
16 |
87,198,925 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAGTTTCCGCAGCACCATTC -3'
(R):5'- GCCCACTTCACAAGTATATTCAG -3'
Sequencing Primer
(F):5'- GCAGCACCATTCGGAAATCGG -3'
(R):5'- CTACTTGGTTCAAAACAGAGC -3'
|
| Posted On |
2017-10-10 |
Incidental Mutation