Incidental Mutation 'IGL03493:Trav2'
ID490734
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Trav2
Ensembl Gene ENSMUSG00000076759
Gene NameT cell receptor alpha variable 2
SynonymsENSMUSG00000072561
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.060) question?
Stock #IGL03493
Quality Score
Status
Chromosome14
Chromosomal Location52567293-52568051 bp(+) (GRCm38)
Type of Mutationutr 5 prime
DNA Base Change (assembly) A to G at 52567288 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000142736 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000103568] [ENSMUST00000196939]
Predicted Effect probably benign
Transcript: ENSMUST00000103568
SMART Domains Protein: ENSMUSP00000100345
Gene: ENSMUSG00000076759

DomainStartEndE-ValueType
Pfam:V-set 16 108 8.5e-13 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000196939
SMART Domains Protein: ENSMUSP00000142736
Gene: ENSMUSG00000076759

DomainStartEndE-ValueType
Pfam:V-set 17 109 1e-12 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 29 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aldoart1 G A 4: 72,851,647 T253I probably damaging Het
Ampd2 T C 3: 108,075,358 E694G probably damaging Het
Atcay C A 10: 81,210,573 E306* probably null Het
Atp13a5 G T 16: 29,297,524 D546E probably benign Het
C2cd2 T C 16: 97,881,661 D125G probably damaging Het
Col23a1 T C 11: 51,564,805 probably null Het
Col9a1 T A 1: 24,221,570 probably benign Het
Cyp4a31 T A 4: 115,570,755 probably null Het
Dnah11 G A 12: 118,012,798 R2708C probably benign Het
Dzip3 T C 16: 48,951,696 I537V probably benign Het
Ezh1 T C 11: 101,203,791 T392A probably benign Het
Hsd17b14 A T 7: 45,556,091 D42V probably damaging Het
Hsf2 A T 10: 57,505,366 I294F probably damaging Het
Ibtk G T 9: 85,718,919 S797R probably benign Het
Kif20b T A 19: 34,959,550 C183* probably null Het
Lnpep G T 17: 17,579,171 A74E probably damaging Het
Map4k1 A T 7: 28,984,151 probably benign Het
Matn1 A G 4: 130,949,998 R173G probably benign Het
Nyap1 A G 5: 137,735,016 I585T probably damaging Het
Olfr1167 G A 2: 88,149,936 P28S probably benign Het
Olfr60 A T 7: 140,345,153 Y279N probably damaging Het
Olfr676 A G 7: 105,035,944 T249A probably damaging Het
Phactr2 A G 10: 13,257,669 V190A probably benign Het
Podnl1 G A 8: 84,132,189 V548I probably benign Het
Rad51c A T 11: 87,397,753 H201Q probably benign Het
Sec63 C A 10: 42,828,941 D730E probably benign Het
Smarcc2 A G 10: 128,461,357 I39M probably damaging Het
Ugt3a2 A G 15: 9,361,483 Y115C probably damaging Het
Zfp955b T G 17: 33,302,545 H329Q probably benign Het
Other mutations in Trav2
AlleleSourceChrCoordTypePredicted EffectPPH Score
R5169:Trav2 UTSW 14 52567302 missense probably benign 0.33
R5475:Trav2 UTSW 14 52567833 missense probably damaging 0.96
Posted On2017-10-20