Incidental Mutation 'R0542:Dsc2'
| ID |
50012 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2a, Dsc2b |
| MMRRC Submission |
038734-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0542 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
20163690-20192611 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 20184283 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 35
(V35A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000074702
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039247
AA Change: V35A
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
AA Change: V35A
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000075214
AA Change: V35A
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
AA Change: V35A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000128464
AA Change: V35A
PolyPhen 2
Score 0.922 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
AA Change: V35A
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Meta Mutation Damage Score |
0.7757 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 95.0%
|
| Validation Efficiency |
99% (70/71) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 69 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abhd12b |
C |
A |
12: 70,210,269 (GRCm39) |
N71K |
possibly damaging |
Het |
| Adgrl2 |
A |
G |
3: 148,564,854 (GRCm39) |
I242T |
probably damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,721,437 (GRCm39) |
S714P |
probably damaging |
Het |
| Agap3 |
G |
A |
5: 24,705,184 (GRCm39) |
R704Q |
possibly damaging |
Het |
| Ankrd11 |
T |
C |
8: 123,622,509 (GRCm39) |
R448G |
probably damaging |
Het |
| Anks1b |
T |
C |
10: 89,909,829 (GRCm39) |
|
probably benign |
Het |
| Caml |
A |
T |
13: 55,770,974 (GRCm39) |
Q24L |
possibly damaging |
Het |
| Cdc14b |
G |
A |
13: 64,391,497 (GRCm39) |
T124I |
probably benign |
Het |
| Clca3a2 |
A |
G |
3: 144,781,571 (GRCm39) |
|
probably benign |
Het |
| Col12a1 |
A |
G |
9: 79,512,610 (GRCm39) |
|
probably null |
Het |
| Crispld1 |
T |
C |
1: 17,816,992 (GRCm39) |
V183A |
possibly damaging |
Het |
| Cstdc1 |
A |
G |
2: 148,624,092 (GRCm39) |
N22S |
probably benign |
Het |
| Dhx40 |
C |
T |
11: 86,695,082 (GRCm39) |
|
probably null |
Het |
| Dmxl1 |
T |
A |
18: 50,026,761 (GRCm39) |
D1956E |
probably benign |
Het |
| Dync2i2 |
A |
G |
2: 29,921,837 (GRCm39) |
V508A |
probably damaging |
Het |
| Elovl2 |
A |
G |
13: 41,345,452 (GRCm39) |
|
probably benign |
Het |
| Gapvd1 |
T |
C |
2: 34,615,048 (GRCm39) |
|
probably benign |
Het |
| Gnaq |
T |
A |
19: 16,196,982 (GRCm39) |
I56N |
probably damaging |
Het |
| Gpr139 |
T |
C |
7: 118,744,306 (GRCm39) |
D93G |
probably benign |
Het |
| Hars1 |
C |
T |
18: 36,904,234 (GRCm39) |
R215H |
probably benign |
Het |
| Helz2 |
C |
A |
2: 180,873,882 (GRCm39) |
W2204L |
probably damaging |
Het |
| Ift70b |
A |
G |
2: 75,767,055 (GRCm39) |
V566A |
probably damaging |
Het |
| Itgb6 |
A |
T |
2: 60,435,480 (GRCm39) |
C757S |
possibly damaging |
Het |
| Kpnb1 |
G |
A |
11: 97,078,398 (GRCm39) |
T5I |
probably benign |
Het |
| Krt82 |
T |
C |
15: 101,454,035 (GRCm39) |
|
probably benign |
Het |
| Lgals9 |
T |
A |
11: 78,860,546 (GRCm39) |
K175N |
possibly damaging |
Het |
| Lrp2 |
A |
G |
2: 69,258,998 (GRCm39) |
I4564T |
probably benign |
Het |
| Mblac1 |
A |
G |
5: 138,192,798 (GRCm39) |
T47A |
possibly damaging |
Het |
| Med12l |
G |
A |
3: 58,949,822 (GRCm39) |
D182N |
probably damaging |
Het |
| Megf9 |
A |
G |
4: 70,353,585 (GRCm39) |
I407T |
probably benign |
Het |
| Mtmr6 |
A |
T |
14: 60,529,578 (GRCm39) |
|
probably null |
Het |
| Mtor |
A |
G |
4: 148,624,907 (GRCm39) |
T2173A |
probably benign |
Het |
| Mzt1 |
A |
T |
14: 99,277,938 (GRCm39) |
|
probably benign |
Het |
| Narf |
T |
C |
11: 121,143,690 (GRCm39) |
L444P |
probably damaging |
Het |
| Nsd1 |
A |
T |
13: 55,408,271 (GRCm39) |
Q1305L |
possibly damaging |
Het |
| Ntsr1 |
A |
G |
2: 180,184,374 (GRCm39) |
Y359C |
probably damaging |
Het |
| Olfm1 |
A |
G |
2: 28,104,640 (GRCm39) |
D159G |
possibly damaging |
Het |
| Or2l13b |
A |
T |
16: 19,348,732 (GRCm39) |
*313R |
probably null |
Het |
| Pcdh1 |
C |
T |
18: 38,322,975 (GRCm39) |
V953I |
probably damaging |
Het |
| Pcdhb11 |
A |
T |
18: 37,556,887 (GRCm39) |
D739V |
probably damaging |
Het |
| Pdgfd |
A |
G |
9: 6,359,769 (GRCm39) |
N280S |
probably damaging |
Het |
| Per2 |
A |
T |
1: 91,366,054 (GRCm39) |
|
probably null |
Het |
| Pfkp |
G |
T |
13: 6,672,028 (GRCm39) |
C122* |
probably null |
Het |
| Plxna4 |
G |
A |
6: 32,169,232 (GRCm39) |
R1322W |
probably damaging |
Het |
| Ppox |
A |
G |
1: 171,106,818 (GRCm39) |
L202P |
probably damaging |
Het |
| Ppp1r3e |
G |
A |
14: 55,114,588 (GRCm39) |
P58L |
probably benign |
Het |
| Prr23a2 |
A |
C |
9: 98,739,086 (GRCm39) |
N148T |
probably benign |
Het |
| Psd |
T |
C |
19: 46,302,649 (GRCm39) |
T842A |
probably damaging |
Het |
| Ranbp2 |
C |
T |
10: 58,314,236 (GRCm39) |
A1652V |
probably benign |
Het |
| Rragd |
G |
A |
4: 33,007,103 (GRCm39) |
V144M |
probably damaging |
Het |
| Sema6a |
T |
G |
18: 47,381,643 (GRCm39) |
D968A |
probably damaging |
Het |
| Slc30a5 |
A |
T |
13: 100,945,793 (GRCm39) |
|
probably null |
Het |
| Snx17 |
G |
T |
5: 31,353,895 (GRCm39) |
|
probably null |
Het |
| Styxl2 |
A |
T |
1: 165,928,853 (GRCm39) |
M253K |
possibly damaging |
Het |
| Syt14 |
G |
T |
1: 192,613,111 (GRCm39) |
T563K |
probably damaging |
Het |
| Tada3 |
T |
C |
6: 113,352,175 (GRCm39) |
K85E |
probably damaging |
Het |
| Tspear |
T |
C |
10: 77,716,921 (GRCm39) |
V532A |
probably benign |
Het |
| Ttn |
A |
T |
2: 76,723,453 (GRCm39) |
C6426S |
possibly damaging |
Het |
| Unc79 |
T |
C |
12: 103,060,437 (GRCm39) |
|
probably benign |
Het |
| Usp19 |
A |
G |
9: 108,371,584 (GRCm39) |
|
probably null |
Het |
| Vav3 |
G |
A |
3: 109,434,746 (GRCm39) |
D426N |
probably damaging |
Het |
| Vezt |
T |
C |
10: 93,842,958 (GRCm39) |
|
probably null |
Het |
| Vldlr |
G |
T |
19: 27,213,655 (GRCm39) |
R114L |
probably benign |
Het |
| Wwc2 |
C |
T |
8: 48,321,414 (GRCm39) |
V567I |
unknown |
Het |
| Zfp423 |
T |
C |
8: 88,507,237 (GRCm39) |
T911A |
probably damaging |
Het |
| Zfp719 |
A |
G |
7: 43,238,677 (GRCm39) |
|
probably null |
Het |
| Zkscan16 |
A |
T |
4: 58,956,597 (GRCm39) |
H293L |
possibly damaging |
Het |
| Zkscan6 |
A |
C |
11: 65,719,525 (GRCm39) |
N515T |
possibly damaging |
Het |
| Znfx1 |
A |
G |
2: 166,897,575 (GRCm39) |
S450P |
probably damaging |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,174,854 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,168,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,167,740 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,176,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,181,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,180,214 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,171,257 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,179,399 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,176,790 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,178,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,174,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,180,136 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,179,300 (GRCm39) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,179,334 (GRCm39) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,166,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0562:Dsc2
|
UTSW |
18 |
20,174,594 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,174,509 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,183,116 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,166,352 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,165,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,178,622 (GRCm39) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,167,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,183,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,179,303 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,165,456 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,178,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,168,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,178,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,178,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,165,408 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,183,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4613:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,183,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5267:Dsc2
|
UTSW |
18 |
20,167,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5445:Dsc2
|
UTSW |
18 |
20,168,360 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,179,336 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,168,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,165,567 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,180,165 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,178,487 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,168,520 (GRCm39) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,184,232 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,179,295 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,165,335 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,183,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,168,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,184,236 (GRCm39) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,168,392 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,174,983 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,168,451 (GRCm39) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,183,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,174,835 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,373 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,183,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,179,342 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,167,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,167,722 (GRCm39) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,171,151 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,176,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,167,764 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,174,773 (GRCm39) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,180,276 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,171,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,179,361 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,168,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCAGTGCCCTGGCTTTGATAC -3'
(R):5'- TGGTTCCCTGAGTAGGAAGTAAGTGC -3'
Sequencing Primer
(F):5'- TGGCTTTGATACCCAGCAC -3'
(R):5'- ACTCCAGATTTCTTACTCTAGTACAC -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation