Incidental Mutation 'R0543:Ccdc180'
| ID |
50043 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc180
|
| Ensembl Gene |
ENSMUSG00000035539 |
| Gene Name |
coiled-coil domain containing 180 |
| Synonyms |
LOC381522, E230008N13Rik |
| MMRRC Submission |
038735-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0543 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
45890303-45950774 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
A to T
at 45900041 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Stop codon
at position 200
(K200*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136714
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000178561]
|
| AlphaFold |
J3QNE4 |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127261
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000149903
AA Change: K192*
|
| SMART Domains |
Protein: ENSMUSP00000119784
Gene: ENSMUSG00000035539
AA Change: K192*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
42 |
N/A |
INTRINSIC |
|
coiled coil region
|
90 |
117 |
N/A |
INTRINSIC |
|
Pfam:DUF4455
|
141 |
609 |
2e-189 |
PFAM |
|
low complexity region
|
628 |
642 |
N/A |
INTRINSIC |
|
low complexity region
|
658 |
675 |
N/A |
INTRINSIC |
|
coiled coil region
|
710 |
780 |
N/A |
INTRINSIC |
|
coiled coil region
|
945 |
979 |
N/A |
INTRINSIC |
|
low complexity region
|
1100 |
1123 |
N/A |
INTRINSIC |
|
Pfam:DUF4456
|
1169 |
1372 |
9.5e-77 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000178561
AA Change: K200*
|
| SMART Domains |
Protein: ENSMUSP00000136714
Gene: ENSMUSG00000035539
AA Change: K200*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
49 |
N/A |
INTRINSIC |
|
coiled coil region
|
98 |
125 |
N/A |
INTRINSIC |
|
Pfam:DUF4455
|
148 |
616 |
7.3e-189 |
PFAM |
|
low complexity region
|
635 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
665 |
682 |
N/A |
INTRINSIC |
|
coiled coil region
|
718 |
788 |
N/A |
INTRINSIC |
|
coiled coil region
|
1121 |
1155 |
N/A |
INTRINSIC |
|
low complexity region
|
1275 |
1298 |
N/A |
INTRINSIC |
|
Pfam:DUF4456
|
1344 |
1547 |
2.2e-76 |
PFAM |
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.3%
|
| Validation Efficiency |
99% (69/70) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a coiled-coil domain. Alternative splicing results in multiple transcript variants encoding different isoforms. A single nucleotide polymorphism (SNP) in this gene has been associated with increased susceptibility to Behcet's Disease (PMID: 19442274). [provided by RefSeq, Dec 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Alox5 |
T |
A |
6: 116,431,278 (GRCm39) |
|
probably null |
Het |
| Apol9b |
A |
G |
15: 77,619,840 (GRCm39) |
N212S |
probably damaging |
Het |
| Ash1l |
T |
A |
3: 88,971,085 (GRCm39) |
|
probably null |
Het |
| Bltp1 |
G |
A |
3: 37,050,607 (GRCm39) |
S2981N |
probably benign |
Het |
| Ccser2 |
A |
T |
14: 36,662,149 (GRCm39) |
M345K |
probably benign |
Het |
| Cdcp2 |
A |
T |
4: 106,954,873 (GRCm39) |
|
probably null |
Het |
| Clca3a1 |
T |
C |
3: 144,454,155 (GRCm39) |
|
probably benign |
Het |
| Cntn3 |
G |
A |
6: 102,246,051 (GRCm39) |
|
probably benign |
Het |
| Col28a1 |
T |
A |
6: 8,075,326 (GRCm39) |
|
probably benign |
Het |
| Dock2 |
A |
G |
11: 34,244,325 (GRCm39) |
F1035S |
probably damaging |
Het |
| Dsg1a |
A |
T |
18: 20,473,920 (GRCm39) |
S998C |
probably damaging |
Het |
| Ecrg4 |
C |
A |
1: 43,781,449 (GRCm39) |
N110K |
possibly damaging |
Het |
| Enox1 |
T |
C |
14: 77,744,399 (GRCm39) |
|
probably benign |
Het |
| Fgfr3 |
A |
G |
5: 33,887,054 (GRCm39) |
M1V |
probably null |
Het |
| Fuca2 |
T |
A |
10: 13,378,870 (GRCm39) |
Y5N |
probably damaging |
Het |
| Git2 |
G |
T |
5: 114,883,592 (GRCm39) |
H42Q |
probably damaging |
Het |
| Gm7964 |
G |
A |
7: 83,405,602 (GRCm39) |
|
noncoding transcript |
Het |
| Hars2 |
G |
A |
18: 36,922,477 (GRCm39) |
E337K |
probably damaging |
Het |
| Hells |
A |
G |
19: 38,956,194 (GRCm39) |
R797G |
probably benign |
Het |
| Hnf1a |
G |
A |
5: 115,088,803 (GRCm39) |
S571L |
probably benign |
Het |
| Hoxa5 |
T |
C |
6: 52,181,320 (GRCm39) |
Y4C |
probably damaging |
Het |
| Inpp4a |
G |
A |
1: 37,408,573 (GRCm39) |
|
probably benign |
Het |
| Ints6 |
T |
C |
14: 62,934,060 (GRCm39) |
I816V |
probably damaging |
Het |
| Itpr1 |
T |
C |
6: 108,492,709 (GRCm39) |
|
probably benign |
Het |
| Itprid2 |
T |
A |
2: 79,474,850 (GRCm39) |
S270T |
possibly damaging |
Het |
| Kcnt2 |
C |
A |
1: 140,537,352 (GRCm39) |
P1037T |
probably damaging |
Het |
| Lyg2 |
T |
A |
1: 37,950,188 (GRCm39) |
M47L |
possibly damaging |
Het |
| Macf1 |
G |
T |
4: 123,270,171 (GRCm39) |
A4648D |
probably damaging |
Het |
| Mcf2l |
T |
C |
8: 13,046,728 (GRCm39) |
|
probably null |
Het |
| Mcm9 |
C |
T |
10: 53,417,694 (GRCm39) |
R3H |
probably damaging |
Het |
| Met |
T |
A |
6: 17,491,969 (GRCm39) |
Y244N |
probably damaging |
Het |
| Mettl14 |
A |
T |
3: 123,168,411 (GRCm39) |
C210S |
possibly damaging |
Het |
| Mrgpra4 |
T |
C |
7: 47,631,058 (GRCm39) |
Y181C |
probably benign |
Het |
| Mtch2 |
T |
C |
2: 90,680,026 (GRCm39) |
V86A |
possibly damaging |
Het |
| Mttp |
A |
T |
3: 137,817,457 (GRCm39) |
I446N |
possibly damaging |
Het |
| Muc4 |
T |
A |
16: 32,577,120 (GRCm39) |
S2207T |
unknown |
Het |
| Muc5b |
A |
G |
7: 141,405,522 (GRCm39) |
T944A |
unknown |
Het |
| Myo15a |
A |
T |
11: 60,369,877 (GRCm39) |
H879L |
probably benign |
Het |
| Nherf4 |
A |
C |
9: 44,160,231 (GRCm39) |
H324Q |
probably damaging |
Het |
| Nkiras2 |
G |
A |
11: 100,515,018 (GRCm39) |
|
probably benign |
Het |
| Nostrin |
T |
G |
2: 69,019,475 (GRCm39) |
*507E |
probably null |
Het |
| Nup205 |
T |
C |
6: 35,175,904 (GRCm39) |
V589A |
probably benign |
Het |
| Or12j3 |
A |
G |
7: 139,953,307 (GRCm39) |
I72T |
probably benign |
Het |
| Or5b21 |
G |
T |
19: 12,839,252 (GRCm39) |
V38F |
probably benign |
Het |
| Or5w17 |
C |
A |
2: 87,583,994 (GRCm39) |
L114F |
probably damaging |
Het |
| Oxct2b |
T |
A |
4: 123,010,782 (GRCm39) |
M234K |
possibly damaging |
Het |
| Pcdha1 |
A |
T |
18: 37,318,121 (GRCm39) |
I945F |
probably damaging |
Het |
| Pik3ca |
G |
A |
3: 32,504,410 (GRCm39) |
|
probably null |
Het |
| Pkhd1l1 |
A |
G |
15: 44,386,887 (GRCm39) |
|
probably null |
Het |
| Plscr1 |
A |
T |
9: 92,140,099 (GRCm39) |
|
probably null |
Het |
| Prkn |
G |
A |
17: 11,286,066 (GRCm39) |
D20N |
probably damaging |
Het |
| Psd |
T |
C |
19: 46,307,956 (GRCm39) |
E684G |
possibly damaging |
Het |
| Rab11fip3 |
T |
C |
17: 26,213,199 (GRCm39) |
E870G |
probably damaging |
Het |
| Rpl22l1 |
C |
A |
3: 28,861,423 (GRCm39) |
Y103* |
probably null |
Het |
| Semp2l2b |
T |
C |
10: 21,942,823 (GRCm39) |
S386G |
possibly damaging |
Het |
| Slc38a4 |
A |
T |
15: 96,914,720 (GRCm39) |
N44K |
possibly damaging |
Het |
| Slco6c1 |
T |
A |
1: 97,055,623 (GRCm39) |
I93F |
probably damaging |
Het |
| Strip1 |
G |
A |
3: 107,534,091 (GRCm39) |
T181M |
possibly damaging |
Het |
| Stxbp5l |
G |
A |
16: 37,028,458 (GRCm39) |
A535V |
probably damaging |
Het |
| Tg |
A |
T |
15: 66,601,446 (GRCm39) |
Q152L |
probably benign |
Het |
| Thada |
T |
C |
17: 84,730,591 (GRCm39) |
T1036A |
probably damaging |
Het |
| Tnfrsf21 |
C |
T |
17: 43,349,104 (GRCm39) |
H239Y |
probably benign |
Het |
| Tns1 |
T |
A |
1: 73,991,856 (GRCm39) |
T941S |
probably benign |
Het |
| Tppp3 |
T |
C |
8: 106,194,840 (GRCm39) |
D97G |
probably benign |
Het |
| Trp53bp1 |
C |
A |
2: 121,082,349 (GRCm39) |
A317S |
probably null |
Het |
| Trpm7 |
T |
C |
2: 126,690,449 (GRCm39) |
I210V |
probably damaging |
Het |
| Ubr1 |
A |
G |
2: 120,711,574 (GRCm39) |
L1440P |
probably damaging |
Het |
| Utp18 |
A |
T |
11: 93,766,661 (GRCm39) |
Y317N |
probably damaging |
Het |
| Zdhhc5 |
T |
A |
2: 84,522,824 (GRCm39) |
|
probably benign |
Het |
| Zfp719 |
A |
G |
7: 43,238,677 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Ccdc180 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01369:Ccdc180
|
APN |
4 |
45,900,256 (GRCm39) |
missense |
probably benign |
|
|
IGL01713:Ccdc180
|
APN |
4 |
45,921,025 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01915:Ccdc180
|
APN |
4 |
45,904,544 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01935:Ccdc180
|
APN |
4 |
45,906,889 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02539:Ccdc180
|
APN |
4 |
45,921,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02982:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
IGL03071:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
IGL03146:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
PIT4687001:Ccdc180
|
UTSW |
4 |
45,949,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0049:Ccdc180
|
UTSW |
4 |
45,930,119 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0049:Ccdc180
|
UTSW |
4 |
45,930,119 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0054:Ccdc180
|
UTSW |
4 |
45,890,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0054:Ccdc180
|
UTSW |
4 |
45,890,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0080:Ccdc180
|
UTSW |
4 |
45,896,205 (GRCm39) |
missense |
probably null |
0.00 |
|
R0082:Ccdc180
|
UTSW |
4 |
45,896,205 (GRCm39) |
missense |
probably null |
0.00 |
|
R0126:Ccdc180
|
UTSW |
4 |
45,912,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0193:Ccdc180
|
UTSW |
4 |
45,914,803 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0276:Ccdc180
|
UTSW |
4 |
45,923,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0362:Ccdc180
|
UTSW |
4 |
45,923,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0380:Ccdc180
|
UTSW |
4 |
45,930,197 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0468:Ccdc180
|
UTSW |
4 |
45,923,271 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0539:Ccdc180
|
UTSW |
4 |
45,922,010 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0546:Ccdc180
|
UTSW |
4 |
45,904,597 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R0612:Ccdc180
|
UTSW |
4 |
45,927,969 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0792:Ccdc180
|
UTSW |
4 |
45,927,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1056:Ccdc180
|
UTSW |
4 |
45,916,375 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1099:Ccdc180
|
UTSW |
4 |
45,914,225 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1136:Ccdc180
|
UTSW |
4 |
45,914,589 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1263:Ccdc180
|
UTSW |
4 |
45,903,887 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1331:Ccdc180
|
UTSW |
4 |
45,909,359 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1522:Ccdc180
|
UTSW |
4 |
45,927,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1819:Ccdc180
|
UTSW |
4 |
45,926,195 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R2022:Ccdc180
|
UTSW |
4 |
45,944,418 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2056:Ccdc180
|
UTSW |
4 |
45,932,477 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2219:Ccdc180
|
UTSW |
4 |
45,944,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2228:Ccdc180
|
UTSW |
4 |
45,948,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2229:Ccdc180
|
UTSW |
4 |
45,948,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2255:Ccdc180
|
UTSW |
4 |
45,921,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2427:Ccdc180
|
UTSW |
4 |
45,929,545 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3001:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3002:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3003:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3110:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3111:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3112:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3898:Ccdc180
|
UTSW |
4 |
45,912,799 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4022:Ccdc180
|
UTSW |
4 |
45,904,560 (GRCm39) |
nonsense |
probably null |
|
|
R4084:Ccdc180
|
UTSW |
4 |
45,950,632 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4377:Ccdc180
|
UTSW |
4 |
45,941,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4595:Ccdc180
|
UTSW |
4 |
45,945,023 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4637:Ccdc180
|
UTSW |
4 |
45,914,443 (GRCm39) |
missense |
probably benign |
|
|
R4811:Ccdc180
|
UTSW |
4 |
45,928,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Ccdc180
|
UTSW |
4 |
45,912,794 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4858:Ccdc180
|
UTSW |
4 |
45,923,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4888:Ccdc180
|
UTSW |
4 |
45,909,308 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4940:Ccdc180
|
UTSW |
4 |
45,917,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4940:Ccdc180
|
UTSW |
4 |
45,917,453 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5042:Ccdc180
|
UTSW |
4 |
45,916,255 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5119:Ccdc180
|
UTSW |
4 |
45,914,603 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5177:Ccdc180
|
UTSW |
4 |
45,917,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5311:Ccdc180
|
UTSW |
4 |
45,917,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5333:Ccdc180
|
UTSW |
4 |
45,890,935 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5448:Ccdc180
|
UTSW |
4 |
45,920,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5510:Ccdc180
|
UTSW |
4 |
45,928,046 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6018:Ccdc180
|
UTSW |
4 |
45,926,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6108:Ccdc180
|
UTSW |
4 |
45,911,389 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6283:Ccdc180
|
UTSW |
4 |
45,902,486 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6483:Ccdc180
|
UTSW |
4 |
45,921,950 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6618:Ccdc180
|
UTSW |
4 |
45,950,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7017:Ccdc180
|
UTSW |
4 |
45,940,934 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7205:Ccdc180
|
UTSW |
4 |
45,914,588 (GRCm39) |
missense |
probably benign |
|
|
R7341:Ccdc180
|
UTSW |
4 |
45,898,644 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7351:Ccdc180
|
UTSW |
4 |
45,903,887 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7418:Ccdc180
|
UTSW |
4 |
45,904,616 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7492:Ccdc180
|
UTSW |
4 |
45,930,009 (GRCm39) |
splice site |
probably null |
|
|
R7573:Ccdc180
|
UTSW |
4 |
45,922,015 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7639:Ccdc180
|
UTSW |
4 |
45,928,043 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7792:Ccdc180
|
UTSW |
4 |
45,890,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7806:Ccdc180
|
UTSW |
4 |
45,912,801 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7812:Ccdc180
|
UTSW |
4 |
45,906,952 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7840:Ccdc180
|
UTSW |
4 |
45,900,461 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7842:Ccdc180
|
UTSW |
4 |
45,909,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8712:Ccdc180
|
UTSW |
4 |
45,920,842 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8818:Ccdc180
|
UTSW |
4 |
45,900,484 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8961:Ccdc180
|
UTSW |
4 |
45,929,573 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R8983:Ccdc180
|
UTSW |
4 |
45,909,359 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9035:Ccdc180
|
UTSW |
4 |
45,906,922 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Ccdc180
|
UTSW |
4 |
45,949,466 (GRCm39) |
nonsense |
probably null |
|
|
R9240:Ccdc180
|
UTSW |
4 |
45,917,566 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9293:Ccdc180
|
UTSW |
4 |
45,944,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9328:Ccdc180
|
UTSW |
4 |
45,902,447 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9346:Ccdc180
|
UTSW |
4 |
45,927,953 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9521:Ccdc180
|
UTSW |
4 |
45,916,283 (GRCm39) |
missense |
probably null |
0.50 |
|
R9653:Ccdc180
|
UTSW |
4 |
45,923,495 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9667:Ccdc180
|
UTSW |
4 |
45,920,861 (GRCm39) |
nonsense |
probably null |
|
|
X0017:Ccdc180
|
UTSW |
4 |
45,909,350 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Z1176:Ccdc180
|
UTSW |
4 |
45,920,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Ccdc180
|
UTSW |
4 |
45,916,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAGTTCATCGTCAATGCTCAGCTCC -3'
(R):5'- TCTGCTGCATGAATCTTTCAGCCAC -3'
Sequencing Primer
(F):5'- GGGCTTAGATAATGACCTTTCTTG -3'
(R):5'- ACTTTTTCCCACAGTTCCAACAG -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation