Incidental Mutation 'R6185:Tanc2'
| ID |
502124 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc2
|
| Ensembl Gene |
ENSMUSG00000053580 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| Synonyms |
5730590C14Rik, 3526402J09Rik |
| MMRRC Submission |
044325-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R6185 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
105480812-105820130 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 105803865 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 297
(N297K)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100330]
|
| AlphaFold |
A2A690 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000089485
AA Change: N209K
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000086912
Gene: ENSMUSG00000053580
AA Change: N209K
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
35 |
63 |
1.16e3 |
SMART |
|
ANK
|
78 |
107 |
3.31e-1 |
SMART |
|
ANK
|
111 |
140 |
7.71e-2 |
SMART |
|
ANK
|
144 |
173 |
6.12e-5 |
SMART |
|
ANK
|
177 |
206 |
8.99e-3 |
SMART |
|
ANK
|
210 |
239 |
5.71e-5 |
SMART |
|
ANK
|
243 |
272 |
2.11e2 |
SMART |
|
Blast:TPR
|
289 |
322 |
3e-14 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100330
AA Change: N1165K
PolyPhen 2
Score 0.140 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000097904
Gene: ENSMUSG00000053580
AA Change: N1165K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
129 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
362 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
823 |
834 |
N/A |
INTRINSIC |
|
ANK
|
846 |
878 |
2.08e3 |
SMART |
|
ANK
|
882 |
913 |
2.97e2 |
SMART |
|
ANK
|
917 |
946 |
5.75e-1 |
SMART |
|
ANK
|
950 |
979 |
8.62e1 |
SMART |
|
ANK
|
990 |
1018 |
1.16e3 |
SMART |
|
ANK
|
1033 |
1062 |
3.31e-1 |
SMART |
|
ANK
|
1066 |
1095 |
7.71e-2 |
SMART |
|
ANK
|
1099 |
1128 |
6.12e-5 |
SMART |
|
ANK
|
1132 |
1161 |
8.99e-3 |
SMART |
|
ANK
|
1165 |
1194 |
5.71e-5 |
SMART |
|
ANK
|
1198 |
1227 |
2.11e2 |
SMART |
|
TPR
|
1244 |
1277 |
3.89e1 |
SMART |
|
TPR
|
1291 |
1324 |
3.61e-2 |
SMART |
|
TPR
|
1325 |
1358 |
2.82e-4 |
SMART |
|
low complexity region
|
1369 |
1406 |
N/A |
INTRINSIC |
|
low complexity region
|
1533 |
1539 |
N/A |
INTRINSIC |
|
low complexity region
|
1787 |
1802 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000146162
AA Change: N297K
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000123674
Gene: ENSMUSG00000053580
AA Change: N297K
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
15 |
46 |
2.97e2 |
SMART |
|
ANK
|
50 |
79 |
5.75e-1 |
SMART |
|
ANK
|
83 |
112 |
8.62e1 |
SMART |
|
ANK
|
123 |
151 |
1.16e3 |
SMART |
|
ANK
|
166 |
195 |
3.31e-1 |
SMART |
|
ANK
|
199 |
228 |
7.71e-2 |
SMART |
|
ANK
|
232 |
261 |
6.12e-5 |
SMART |
|
ANK
|
265 |
294 |
8.99e-3 |
SMART |
|
ANK
|
298 |
327 |
5.71e-5 |
SMART |
|
ANK
|
331 |
360 |
3.44e1 |
SMART |
|
TPR
|
387 |
420 |
3.89e1 |
SMART |
|
TPR
|
434 |
467 |
3.61e-2 |
SMART |
|
TPR
|
468 |
501 |
2.82e-4 |
SMART |
|
low complexity region
|
512 |
549 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
682 |
N/A |
INTRINSIC |
|
low complexity region
|
930 |
945 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000147975
|
| Meta Mutation Damage Score |
0.0863 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
96% (80/83) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector die prior to E12. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca1 |
A |
T |
4: 53,078,089 (GRCm39) |
H894Q |
probably benign |
Het |
| Abca4 |
A |
T |
3: 121,919,789 (GRCm39) |
I1024F |
probably damaging |
Het |
| Acadl |
A |
G |
1: 66,877,522 (GRCm39) |
V343A |
possibly damaging |
Het |
| Akr1e1 |
T |
A |
13: 4,651,252 (GRCm39) |
I123L |
probably benign |
Het |
| Angptl2 |
T |
C |
2: 33,119,026 (GRCm39) |
S267P |
probably benign |
Het |
| Ap2a1 |
T |
G |
7: 44,565,594 (GRCm39) |
K91T |
probably damaging |
Het |
| Bend7 |
A |
T |
2: 4,793,333 (GRCm39) |
Q379L |
probably damaging |
Het |
| Bicdl1 |
C |
T |
5: 115,808,212 (GRCm39) |
|
probably null |
Het |
| Cachd1 |
C |
A |
4: 100,838,228 (GRCm39) |
Y830* |
probably null |
Het |
| Ccdc158 |
T |
A |
5: 92,814,713 (GRCm39) |
I38F |
possibly damaging |
Het |
| Cep97 |
T |
A |
16: 55,735,455 (GRCm39) |
M448L |
probably benign |
Het |
| Chd9 |
A |
G |
8: 91,775,765 (GRCm39) |
D2572G |
probably damaging |
Het |
| Clcnkb |
C |
T |
4: 141,141,825 (GRCm39) |
V54M |
probably benign |
Het |
| Cln8 |
A |
G |
8: 14,946,544 (GRCm39) |
D186G |
probably benign |
Het |
| Crxos |
C |
T |
7: 15,636,805 (GRCm39) |
S22L |
possibly damaging |
Het |
| Cx3cr1 |
A |
T |
9: 119,880,444 (GRCm39) |
H319Q |
probably benign |
Het |
| Cyp2j6 |
G |
C |
4: 96,424,323 (GRCm39) |
L145V |
probably damaging |
Het |
| Dmrta1 |
A |
G |
4: 89,580,005 (GRCm39) |
R322G |
probably damaging |
Het |
| Dpf1 |
A |
G |
7: 29,010,696 (GRCm39) |
E103G |
possibly damaging |
Het |
| Dsg1b |
T |
G |
18: 20,532,543 (GRCm39) |
V529G |
probably benign |
Het |
| Dst |
G |
A |
1: 34,212,161 (GRCm39) |
V1361I |
probably damaging |
Het |
| Epha4 |
T |
C |
1: 77,483,743 (GRCm39) |
I89V |
probably damaging |
Het |
| Etfdh |
G |
T |
3: 79,513,114 (GRCm39) |
H370N |
probably benign |
Het |
| Fam186a |
A |
G |
15: 99,845,530 (GRCm39) |
I238T |
unknown |
Het |
| Fbxl5 |
T |
A |
5: 43,978,894 (GRCm39) |
S19C |
probably benign |
Het |
| Fkbpl |
G |
A |
17: 34,864,303 (GRCm39) |
A24T |
probably benign |
Het |
| Fryl |
A |
G |
5: 73,270,131 (GRCm39) |
V367A |
probably benign |
Het |
| Gm19410 |
T |
A |
8: 36,274,664 (GRCm39) |
L1495H |
possibly damaging |
Het |
| Gm19965 |
A |
G |
1: 116,749,003 (GRCm39) |
E228G |
possibly damaging |
Het |
| Gpr89 |
C |
A |
3: 96,798,149 (GRCm39) |
C169F |
probably damaging |
Het |
| Hmcn1 |
A |
T |
1: 150,491,189 (GRCm39) |
|
probably null |
Het |
| Hsph1 |
A |
T |
5: 149,541,160 (GRCm39) |
C753S |
probably damaging |
Het |
| Igf2 |
T |
A |
7: 142,212,118 (GRCm39) |
S4C |
possibly damaging |
Het |
| Kansl3 |
A |
T |
1: 36,385,099 (GRCm39) |
S486T |
probably damaging |
Het |
| Khdrbs1 |
G |
C |
4: 129,636,068 (GRCm39) |
|
probably benign |
Het |
| Lnx1 |
A |
T |
5: 74,846,269 (GRCm39) |
C60* |
probably null |
Het |
| Lrpprc |
T |
C |
17: 85,074,452 (GRCm39) |
D485G |
probably benign |
Het |
| Ly6i |
A |
T |
15: 74,851,879 (GRCm39) |
S97T |
possibly damaging |
Het |
| Me2 |
G |
A |
18: 73,924,199 (GRCm39) |
Q338* |
probably null |
Het |
| Med16 |
A |
T |
10: 79,732,197 (GRCm39) |
L790Q |
probably damaging |
Het |
| Muc16 |
G |
T |
9: 18,565,769 (GRCm39) |
T2250K |
unknown |
Het |
| Myo10 |
T |
G |
15: 25,726,596 (GRCm39) |
F273C |
probably damaging |
Het |
| Neil3 |
T |
A |
8: 54,052,182 (GRCm39) |
H472L |
probably benign |
Het |
| Nrxn1 |
T |
A |
17: 90,344,564 (GRCm39) |
S57C |
probably damaging |
Het |
| Nup188 |
A |
T |
2: 30,231,722 (GRCm39) |
T1439S |
probably damaging |
Het |
| Or10g3 |
T |
C |
14: 52,610,019 (GRCm39) |
T164A |
possibly damaging |
Het |
| Or10g7 |
T |
C |
9: 39,905,420 (GRCm39) |
F105L |
probably benign |
Het |
| Or5w10 |
A |
G |
2: 87,375,087 (GRCm39) |
M267T |
possibly damaging |
Het |
| Otud7a |
T |
A |
7: 63,408,133 (GRCm39) |
L812Q |
probably damaging |
Het |
| Paip2b |
C |
T |
6: 83,786,952 (GRCm39) |
A95T |
probably benign |
Het |
| Pax4 |
C |
T |
6: 28,446,347 (GRCm39) |
V49I |
probably damaging |
Het |
| Plek |
C |
T |
11: 16,931,829 (GRCm39) |
A341T |
probably damaging |
Het |
| Prkag1 |
G |
A |
15: 98,723,595 (GRCm39) |
P10L |
probably benign |
Het |
| R3hdm1 |
A |
C |
1: 128,079,598 (GRCm39) |
D15A |
possibly damaging |
Het |
| Rad54b |
A |
T |
4: 11,593,804 (GRCm39) |
D144V |
possibly damaging |
Het |
| Rmi2 |
C |
T |
16: 10,704,073 (GRCm39) |
T138I |
probably benign |
Het |
| Sbf1 |
A |
G |
15: 89,189,814 (GRCm39) |
L379P |
probably damaging |
Het |
| Sec14l3 |
A |
T |
11: 4,025,244 (GRCm39) |
I285F |
probably damaging |
Het |
| Sec31b |
A |
T |
19: 44,531,723 (GRCm39) |
I62N |
possibly damaging |
Het |
| Selp |
A |
G |
1: 163,953,915 (GRCm39) |
N72D |
probably damaging |
Het |
| Sipa1l1 |
T |
A |
12: 82,471,802 (GRCm39) |
S1261T |
probably damaging |
Het |
| Sipa1l2 |
A |
T |
8: 126,194,992 (GRCm39) |
Y915* |
probably null |
Het |
| Slc22a27 |
A |
T |
19: 7,903,953 (GRCm39) |
D61E |
probably benign |
Het |
| Slc2a7 |
A |
G |
4: 150,233,450 (GRCm39) |
T8A |
probably benign |
Het |
| Slc5a2 |
T |
C |
7: 127,870,349 (GRCm39) |
I529T |
probably damaging |
Het |
| Spart |
A |
C |
3: 55,024,640 (GRCm39) |
Q78H |
probably damaging |
Het |
| Spocd1 |
T |
C |
4: 129,850,242 (GRCm39) |
I756T |
probably benign |
Het |
| Stc1 |
G |
A |
14: 69,275,813 (GRCm39) |
C202Y |
probably damaging |
Het |
| Stk10 |
A |
G |
11: 32,527,749 (GRCm39) |
T166A |
probably benign |
Het |
| Syt6 |
A |
T |
3: 103,492,844 (GRCm39) |
D32V |
probably damaging |
Het |
| Tanc1 |
T |
A |
2: 59,621,929 (GRCm39) |
|
probably null |
Het |
| Telo2 |
A |
G |
17: 25,321,014 (GRCm39) |
S734P |
probably benign |
Het |
| Tfrc |
T |
A |
16: 32,437,090 (GRCm39) |
Y250N |
probably benign |
Het |
| Tmem97 |
C |
T |
11: 78,434,388 (GRCm39) |
W65* |
probably null |
Het |
| Ubr3 |
T |
C |
2: 69,768,621 (GRCm39) |
M476T |
probably damaging |
Het |
| Ubtf |
T |
C |
11: 102,204,849 (GRCm39) |
T117A |
probably damaging |
Het |
| Usp17lb |
T |
A |
7: 104,490,631 (GRCm39) |
M99L |
probably benign |
Het |
| Uvrag |
A |
C |
7: 98,790,039 (GRCm39) |
|
probably null |
Het |
| Vmn2r63 |
A |
G |
7: 42,578,435 (GRCm39) |
S153P |
probably damaging |
Het |
| Vmn2r90 |
A |
T |
17: 17,953,644 (GRCm39) |
T603S |
probably damaging |
Het |
| Vps8 |
C |
A |
16: 21,288,891 (GRCm39) |
L417I |
probably damaging |
Het |
|
| Other mutations in Tanc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00501:Tanc2
|
APN |
11 |
105,814,046 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL00688:Tanc2
|
APN |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00709:Tanc2
|
APN |
11 |
105,689,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01013:Tanc2
|
APN |
11 |
105,515,891 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01141:Tanc2
|
APN |
11 |
105,777,300 (GRCm39) |
splice site |
probably benign |
|
|
IGL01386:Tanc2
|
APN |
11 |
105,777,207 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01433:Tanc2
|
APN |
11 |
105,701,348 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL01562:Tanc2
|
APN |
11 |
105,670,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01979:Tanc2
|
APN |
11 |
105,667,746 (GRCm39) |
missense |
probably benign |
|
|
IGL02104:Tanc2
|
APN |
11 |
105,670,959 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02434:Tanc2
|
APN |
11 |
105,670,868 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02534:Tanc2
|
APN |
11 |
105,725,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02568:Tanc2
|
APN |
11 |
105,667,777 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Tanc2
|
APN |
11 |
105,803,918 (GRCm39) |
splice site |
probably null |
|
|
R0595:Tanc2
|
UTSW |
11 |
105,605,003 (GRCm39) |
splice site |
probably null |
|
|
R1131:Tanc2
|
UTSW |
11 |
105,725,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1320:Tanc2
|
UTSW |
11 |
105,777,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1487:Tanc2
|
UTSW |
11 |
105,814,460 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1497:Tanc2
|
UTSW |
11 |
105,812,963 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1692:Tanc2
|
UTSW |
11 |
105,748,326 (GRCm39) |
missense |
probably benign |
|
|
R1712:Tanc2
|
UTSW |
11 |
105,790,606 (GRCm39) |
missense |
probably benign |
|
|
R1793:Tanc2
|
UTSW |
11 |
105,515,859 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1812:Tanc2
|
UTSW |
11 |
105,777,212 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1905:Tanc2
|
UTSW |
11 |
105,813,689 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1959:Tanc2
|
UTSW |
11 |
105,801,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Tanc2
|
UTSW |
11 |
105,689,558 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2122:Tanc2
|
UTSW |
11 |
105,786,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2174:Tanc2
|
UTSW |
11 |
105,801,135 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2341:Tanc2
|
UTSW |
11 |
105,725,877 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2497:Tanc2
|
UTSW |
11 |
105,564,319 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3438:Tanc2
|
UTSW |
11 |
105,748,401 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3711:Tanc2
|
UTSW |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3765:Tanc2
|
UTSW |
11 |
105,805,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3890:Tanc2
|
UTSW |
11 |
105,689,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Tanc2
|
UTSW |
11 |
105,804,888 (GRCm39) |
intron |
probably benign |
|
|
R4609:Tanc2
|
UTSW |
11 |
105,801,066 (GRCm39) |
missense |
probably benign |
0.24 |
|
R4674:Tanc2
|
UTSW |
11 |
105,758,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4928:Tanc2
|
UTSW |
11 |
105,758,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5008:Tanc2
|
UTSW |
11 |
105,515,886 (GRCm39) |
start codon destroyed |
probably null |
0.46 |
|
R5010:Tanc2
|
UTSW |
11 |
105,670,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5135:Tanc2
|
UTSW |
11 |
105,748,379 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5385:Tanc2
|
UTSW |
11 |
105,667,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5409:Tanc2
|
UTSW |
11 |
105,758,311 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5419:Tanc2
|
UTSW |
11 |
105,813,709 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5501:Tanc2
|
UTSW |
11 |
105,805,811 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5590:Tanc2
|
UTSW |
11 |
105,814,132 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5651:Tanc2
|
UTSW |
11 |
105,689,526 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5798:Tanc2
|
UTSW |
11 |
105,812,681 (GRCm39) |
small deletion |
probably benign |
|
|
R5876:Tanc2
|
UTSW |
11 |
105,813,439 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5889:Tanc2
|
UTSW |
11 |
105,812,633 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5958:Tanc2
|
UTSW |
11 |
105,731,451 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5999:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,814,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6025:Tanc2
|
UTSW |
11 |
105,787,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6025:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6048:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Tanc2
|
UTSW |
11 |
105,748,382 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6821:Tanc2
|
UTSW |
11 |
105,777,316 (GRCm39) |
splice site |
probably null |
|
|
R6846:Tanc2
|
UTSW |
11 |
105,689,479 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6857:Tanc2
|
UTSW |
11 |
105,801,114 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6904:Tanc2
|
UTSW |
11 |
105,726,056 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7009:Tanc2
|
UTSW |
11 |
105,731,525 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7017:Tanc2
|
UTSW |
11 |
105,813,934 (GRCm39) |
missense |
probably benign |
|
|
R7371:Tanc2
|
UTSW |
11 |
105,689,422 (GRCm39) |
missense |
probably benign |
|
|
R7556:Tanc2
|
UTSW |
11 |
105,799,857 (GRCm39) |
missense |
|
|
|
R7630:Tanc2
|
UTSW |
11 |
105,667,734 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7693:Tanc2
|
UTSW |
11 |
105,814,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7757:Tanc2
|
UTSW |
11 |
105,667,684 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7807:Tanc2
|
UTSW |
11 |
105,758,480 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7878:Tanc2
|
UTSW |
11 |
105,804,241 (GRCm39) |
missense |
|
|
|
R7895:Tanc2
|
UTSW |
11 |
105,812,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Tanc2
|
UTSW |
11 |
105,787,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8099:Tanc2
|
UTSW |
11 |
105,754,833 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Tanc2
|
UTSW |
11 |
105,725,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8133:Tanc2
|
UTSW |
11 |
105,814,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8422:Tanc2
|
UTSW |
11 |
105,726,014 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8527:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8542:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8834:Tanc2
|
UTSW |
11 |
105,807,845 (GRCm39) |
missense |
|
|
|
R8912:Tanc2
|
UTSW |
11 |
105,758,153 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8927:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8928:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8968:Tanc2
|
UTSW |
11 |
105,758,400 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9065:Tanc2
|
UTSW |
11 |
105,689,518 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Tanc2
|
UTSW |
11 |
105,758,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9108:Tanc2
|
UTSW |
11 |
105,810,580 (GRCm39) |
intron |
probably benign |
|
|
R9131:Tanc2
|
UTSW |
11 |
105,689,603 (GRCm39) |
missense |
probably benign |
|
|
R9294:Tanc2
|
UTSW |
11 |
105,777,284 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9445:Tanc2
|
UTSW |
11 |
105,758,290 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
X0027:Tanc2
|
UTSW |
11 |
105,726,009 (GRCm39) |
missense |
probably benign |
0.26 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTGTCCTCAGTCCTGTTAAAAC -3'
(R):5'- TCAAACTGCTTGTCTGAACCAG -3'
Sequencing Primer
(F):5'- TAGCTGGGCTTGTCTGAA -3'
(R):5'- AAACTGCTTGTCTGAACCAGTATCTC -3'
|
| Posted On |
2018-02-27 |
Incidental Mutation