Incidental Mutation 'R6190:Gria4'
| ID |
502478 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Gria4
|
| Ensembl Gene |
ENSMUSG00000025892 |
| Gene Name |
glutamate receptor, ionotropic, AMPA4 (alpha 4) |
| Synonyms |
Glur-4, spkw1, Gluralpha4, Glur4 |
| MMRRC Submission |
044330-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.690)
|
| Stock # |
R6190 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
4417896-4796234 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 4420199 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 888
(I888F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000148533
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000027020]
[ENSMUST00000063508]
[ENSMUST00000212533]
|
| AlphaFold |
Q9Z2W8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000027020
AA Change: I888F
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000027020
Gene: ENSMUSG00000025892
AA Change: I888F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
Pfam:ANF_receptor
|
39 |
380 |
3e-61 |
PFAM |
|
PBPe
|
416 |
791 |
8.23e-129 |
SMART |
|
Lig_chan-Glu_bd
|
426 |
491 |
3.4e-31 |
SMART |
|
low complexity region
|
821 |
833 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000063508
AA Change: I888F
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000066980
Gene: ENSMUSG00000025892
AA Change: I888F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
Pfam:ANF_receptor
|
39 |
380 |
2.5e-71 |
PFAM |
|
PBPe
|
416 |
791 |
2.06e-129 |
SMART |
|
Lig_chan-Glu_bd
|
426 |
491 |
3.4e-31 |
SMART |
|
low complexity region
|
821 |
833 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212533
AA Change: I888F
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a targeted mutation display hyperactivity, decreased thermal nociception, and abnormal sensitivity to pharmacologically induced seizures. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abat |
T |
A |
16: 8,423,472 (GRCm39) |
L224Q |
probably damaging |
Het |
| Abcc5 |
A |
G |
16: 20,211,529 (GRCm39) |
M478T |
probably benign |
Het |
| Acot10 |
T |
C |
15: 20,665,871 (GRCm39) |
D290G |
possibly damaging |
Het |
| Actr3b |
A |
G |
5: 26,036,688 (GRCm39) |
Q167R |
probably benign |
Het |
| Actr8 |
C |
T |
14: 29,713,674 (GRCm39) |
R565* |
probably null |
Het |
| Adcy7 |
C |
T |
8: 89,052,358 (GRCm39) |
|
probably null |
Het |
| Adgrb3 |
C |
T |
1: 25,459,728 (GRCm39) |
V576I |
probably benign |
Het |
| Adgrv1 |
T |
A |
13: 81,607,882 (GRCm39) |
|
probably null |
Het |
| Adgrv1 |
A |
T |
13: 81,672,898 (GRCm39) |
|
probably null |
Het |
| Ak2 |
A |
G |
4: 128,892,976 (GRCm39) |
D45G |
probably damaging |
Het |
| Ak9 |
C |
G |
10: 41,298,403 (GRCm39) |
Q1489E |
unknown |
Het |
| Ak9 |
A |
T |
10: 41,298,404 (GRCm39) |
Q1489L |
unknown |
Het |
| Akap12 |
C |
A |
10: 4,306,268 (GRCm39) |
S1026Y |
possibly damaging |
Het |
| Ankhd1 |
T |
G |
18: 36,744,862 (GRCm39) |
S601A |
possibly damaging |
Het |
| Apba2 |
A |
T |
7: 64,389,628 (GRCm39) |
E508V |
probably damaging |
Het |
| Arhgap18 |
A |
G |
10: 26,722,031 (GRCm39) |
M1V |
probably null |
Het |
| Arhgef10l |
G |
A |
4: 140,270,073 (GRCm39) |
T865M |
possibly damaging |
Het |
| Bdh1 |
T |
A |
16: 31,268,715 (GRCm39) |
V150D |
probably damaging |
Het |
| Becn1 |
A |
G |
11: 101,186,200 (GRCm39) |
C135R |
probably damaging |
Het |
| C2cd4d |
A |
G |
3: 94,271,226 (GRCm39) |
D164G |
probably benign |
Het |
| Cacna1e |
C |
A |
1: 154,362,316 (GRCm39) |
V424F |
possibly damaging |
Het |
| Capn7 |
C |
A |
14: 31,085,560 (GRCm39) |
T511K |
probably benign |
Het |
| Cdc5l |
G |
A |
17: 45,718,943 (GRCm39) |
P558S |
probably benign |
Het |
| Cep170 |
T |
A |
1: 176,609,975 (GRCm39) |
H112L |
probably damaging |
Het |
| Cfap61 |
C |
T |
2: 145,789,053 (GRCm39) |
T19M |
probably benign |
Het |
| Clca3a1 |
A |
G |
3: 144,463,821 (GRCm39) |
V152A |
probably benign |
Het |
| Cnot10 |
G |
T |
9: 114,461,791 (GRCm39) |
T24K |
probably damaging |
Het |
| Cntnap5b |
T |
A |
1: 100,306,800 (GRCm39) |
I839N |
possibly damaging |
Het |
| Cyp4f13 |
A |
T |
17: 33,148,847 (GRCm39) |
D299E |
probably damaging |
Het |
| Dclk1 |
A |
G |
3: 55,395,232 (GRCm39) |
E128G |
probably damaging |
Het |
| Dennd1b |
T |
C |
1: 139,061,413 (GRCm39) |
I365T |
probably damaging |
Het |
| Dgcr8 |
T |
C |
16: 18,102,274 (GRCm39) |
T3A |
probably damaging |
Het |
| Dld |
A |
C |
12: 31,394,847 (GRCm39) |
I58S |
probably damaging |
Het |
| Dlg5 |
T |
A |
14: 24,240,506 (GRCm39) |
R248S |
probably damaging |
Het |
| Eml2 |
G |
A |
7: 18,935,088 (GRCm39) |
V432I |
probably damaging |
Het |
| Faf1 |
C |
T |
4: 109,719,012 (GRCm39) |
L373F |
probably damaging |
Het |
| Fam171b |
C |
T |
2: 83,707,042 (GRCm39) |
T304I |
probably benign |
Het |
| Fcgrt |
A |
T |
7: 44,751,622 (GRCm39) |
|
probably null |
Het |
| Gimap9 |
T |
C |
6: 48,655,285 (GRCm39) |
W291R |
probably damaging |
Het |
| Gm4847 |
G |
A |
1: 166,457,892 (GRCm39) |
A487V |
probably damaging |
Het |
| Hapln2 |
T |
A |
3: 87,930,600 (GRCm39) |
I224F |
probably damaging |
Het |
| Herc1 |
T |
G |
9: 66,283,663 (GRCm39) |
L332R |
possibly damaging |
Het |
| Hmgxb4 |
T |
C |
8: 75,749,927 (GRCm39) |
V481A |
probably benign |
Het |
| Htr1d |
T |
C |
4: 136,170,109 (GRCm39) |
S113P |
probably damaging |
Het |
| Ift81 |
T |
C |
5: 122,689,163 (GRCm39) |
Q651R |
probably benign |
Het |
| Il17ra |
T |
C |
6: 120,452,234 (GRCm39) |
S199P |
probably damaging |
Het |
| Itih2 |
T |
C |
2: 10,103,318 (GRCm39) |
N723S |
probably benign |
Het |
| Jak1 |
A |
T |
4: 101,032,325 (GRCm39) |
V427E |
probably damaging |
Het |
| Krt23 |
C |
T |
11: 99,376,584 (GRCm39) |
D191N |
probably damaging |
Het |
| Lingo1 |
T |
A |
9: 56,526,934 (GRCm39) |
I552F |
possibly damaging |
Het |
| Llgl2 |
G |
A |
11: 115,737,812 (GRCm39) |
R199Q |
probably benign |
Het |
| Lrrc37a |
G |
T |
11: 103,392,042 (GRCm39) |
Q1128K |
possibly damaging |
Het |
| Lrrc74a |
T |
C |
12: 86,783,263 (GRCm39) |
V36A |
probably benign |
Het |
| M1ap |
T |
A |
6: 82,980,877 (GRCm39) |
D254E |
possibly damaging |
Het |
| Mal2 |
C |
T |
15: 54,434,794 (GRCm39) |
|
probably benign |
Het |
| Mbnl2 |
A |
G |
14: 120,622,833 (GRCm39) |
T124A |
probably benign |
Het |
| Nfatc1 |
A |
G |
18: 80,755,885 (GRCm39) |
S33P |
probably benign |
Het |
| Nfkbid |
A |
G |
7: 30,125,162 (GRCm39) |
N253S |
probably damaging |
Het |
| Ngfr |
T |
A |
11: 95,465,267 (GRCm39) |
I194F |
probably benign |
Het |
| Nhsl1 |
A |
G |
10: 18,345,789 (GRCm39) |
|
probably benign |
Het |
| Nol9 |
T |
A |
4: 152,125,691 (GRCm39) |
I214N |
possibly damaging |
Het |
| Or1o3 |
A |
G |
17: 37,573,635 (GRCm39) |
S307P |
probably benign |
Het |
| Or5p56 |
T |
C |
7: 107,590,307 (GRCm39) |
L245P |
probably damaging |
Het |
| Or8k3 |
T |
A |
2: 86,058,578 (GRCm39) |
T246S |
possibly damaging |
Het |
| Pax3 |
C |
T |
1: 78,169,186 (GRCm39) |
S160N |
possibly damaging |
Het |
| Pde3b |
A |
G |
7: 114,122,267 (GRCm39) |
|
probably null |
Het |
| Pde5a |
A |
C |
3: 122,522,956 (GRCm39) |
E21A |
probably benign |
Het |
| Plcxd1 |
A |
G |
5: 110,250,469 (GRCm39) |
E270G |
probably damaging |
Het |
| Plxna1 |
T |
A |
6: 89,333,586 (GRCm39) |
K348* |
probably null |
Het |
| Pramel34 |
A |
T |
5: 93,785,937 (GRCm39) |
N114K |
probably benign |
Het |
| Prb1b |
T |
A |
6: 132,289,692 (GRCm39) |
H44L |
unknown |
Het |
| Psg21 |
G |
T |
7: 18,388,926 (GRCm39) |
D55E |
possibly damaging |
Het |
| Rasa1 |
C |
A |
13: 85,381,814 (GRCm39) |
A493S |
probably benign |
Het |
| Raver2 |
A |
G |
4: 100,990,814 (GRCm39) |
I396V |
probably benign |
Het |
| Rpa2 |
A |
G |
4: 132,502,331 (GRCm39) |
K138E |
probably benign |
Het |
| Rsad1 |
T |
C |
11: 94,439,062 (GRCm39) |
N133D |
probably damaging |
Het |
| Rusc1 |
T |
C |
3: 88,999,188 (GRCm39) |
D198G |
probably benign |
Het |
| Samsn1 |
A |
T |
16: 75,667,803 (GRCm39) |
Y258N |
probably damaging |
Het |
| Scap |
A |
G |
9: 110,203,135 (GRCm39) |
N270D |
probably benign |
Het |
| Shisal2a |
A |
T |
4: 108,225,052 (GRCm39) |
I170N |
probably damaging |
Het |
| Smpd4 |
T |
C |
16: 17,449,877 (GRCm39) |
Y200H |
probably damaging |
Het |
| Steap2 |
A |
G |
5: 5,725,881 (GRCm39) |
V381A |
probably damaging |
Het |
| Syk |
C |
T |
13: 52,765,089 (GRCm39) |
T72I |
probably damaging |
Het |
| Tbc1d14 |
T |
C |
5: 36,729,228 (GRCm39) |
D66G |
possibly damaging |
Het |
| Tcp11 |
A |
G |
17: 28,290,691 (GRCm39) |
Y223H |
probably benign |
Het |
| Timm9 |
A |
G |
12: 71,173,124 (GRCm39) |
S8P |
probably benign |
Het |
| Tmpo |
T |
C |
10: 91,000,069 (GRCm39) |
|
probably null |
Het |
| Vezf1 |
T |
C |
11: 87,967,012 (GRCm39) |
M81T |
probably benign |
Het |
| Vipr1 |
T |
A |
9: 121,493,719 (GRCm39) |
W257R |
probably damaging |
Het |
| Vmn1r237 |
G |
A |
17: 21,534,556 (GRCm39) |
G93D |
probably damaging |
Het |
| Vmn2r6 |
A |
G |
3: 64,445,424 (GRCm39) |
V678A |
probably benign |
Het |
| Vmn2r85 |
T |
C |
10: 130,261,330 (GRCm39) |
T336A |
possibly damaging |
Het |
| Xpnpep3 |
C |
A |
15: 81,322,300 (GRCm39) |
D296E |
probably benign |
Het |
| Zfp35 |
C |
A |
18: 24,137,118 (GRCm39) |
H487Q |
probably benign |
Het |
| Zfp606 |
A |
T |
7: 12,227,928 (GRCm39) |
Y625F |
probably damaging |
Het |
| Zfp677 |
A |
G |
17: 21,617,530 (GRCm39) |
T196A |
possibly damaging |
Het |
| Zmym1 |
T |
C |
4: 126,941,677 (GRCm39) |
I904V |
probably damaging |
Het |
|
| Other mutations in Gria4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00814:Gria4
|
APN |
9 |
4,472,202 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01451:Gria4
|
APN |
9 |
4,503,652 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01533:Gria4
|
APN |
9 |
4,502,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01994:Gria4
|
APN |
9 |
4,537,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02078:Gria4
|
APN |
9 |
4,793,878 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02183:Gria4
|
APN |
9 |
4,502,460 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02351:Gria4
|
APN |
9 |
4,456,206 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02358:Gria4
|
APN |
9 |
4,456,206 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL03118:Gria4
|
APN |
9 |
4,793,804 (GRCm39) |
splice site |
probably benign |
|
|
IGL03131:Gria4
|
APN |
9 |
4,432,876 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03148:Gria4
|
APN |
9 |
4,464,295 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03264:Gria4
|
APN |
9 |
4,513,288 (GRCm39) |
missense |
probably benign |
|
|
PIT4812001:Gria4
|
UTSW |
9 |
4,427,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0018:Gria4
|
UTSW |
9 |
4,432,843 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R0295:Gria4
|
UTSW |
9 |
4,793,840 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0654:Gria4
|
UTSW |
9 |
4,464,372 (GRCm39) |
missense |
probably benign |
0.32 |
|
R0690:Gria4
|
UTSW |
9 |
4,427,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0992:Gria4
|
UTSW |
9 |
4,795,238 (GRCm39) |
missense |
probably benign |
|
|
R1517:Gria4
|
UTSW |
9 |
4,793,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1673:Gria4
|
UTSW |
9 |
4,537,637 (GRCm39) |
nonsense |
probably null |
|
|
R1713:Gria4
|
UTSW |
9 |
4,424,448 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1961:Gria4
|
UTSW |
9 |
4,519,546 (GRCm39) |
splice site |
probably benign |
|
|
R2137:Gria4
|
UTSW |
9 |
4,427,026 (GRCm39) |
intron |
probably benign |
|
|
R2397:Gria4
|
UTSW |
9 |
4,537,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2870:Gria4
|
UTSW |
9 |
4,503,614 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2870:Gria4
|
UTSW |
9 |
4,503,614 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3014:Gria4
|
UTSW |
9 |
4,464,294 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3412:Gria4
|
UTSW |
9 |
4,513,278 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3732:Gria4
|
UTSW |
9 |
4,513,295 (GRCm39) |
missense |
probably benign |
|
|
R3732:Gria4
|
UTSW |
9 |
4,513,295 (GRCm39) |
missense |
probably benign |
|
|
R3733:Gria4
|
UTSW |
9 |
4,513,295 (GRCm39) |
missense |
probably benign |
|
|
R3897:Gria4
|
UTSW |
9 |
4,513,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4404:Gria4
|
UTSW |
9 |
4,464,489 (GRCm39) |
splice site |
probably null |
|
|
R4457:Gria4
|
UTSW |
9 |
4,427,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4672:Gria4
|
UTSW |
9 |
4,664,981 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4865:Gria4
|
UTSW |
9 |
4,464,295 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5092:Gria4
|
UTSW |
9 |
4,472,176 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5109:Gria4
|
UTSW |
9 |
4,472,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5202:Gria4
|
UTSW |
9 |
4,424,330 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5828:Gria4
|
UTSW |
9 |
4,432,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5945:Gria4
|
UTSW |
9 |
4,456,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5985:Gria4
|
UTSW |
9 |
4,503,593 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6036:Gria4
|
UTSW |
9 |
4,537,646 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6036:Gria4
|
UTSW |
9 |
4,537,646 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6111:Gria4
|
UTSW |
9 |
4,502,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6280:Gria4
|
UTSW |
9 |
4,456,072 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6406:Gria4
|
UTSW |
9 |
4,427,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6470:Gria4
|
UTSW |
9 |
4,503,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6485:Gria4
|
UTSW |
9 |
4,464,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6612:Gria4
|
UTSW |
9 |
4,472,206 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6848:Gria4
|
UTSW |
9 |
4,793,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7046:Gria4
|
UTSW |
9 |
4,420,278 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7210:Gria4
|
UTSW |
9 |
4,464,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7284:Gria4
|
UTSW |
9 |
4,472,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7475:Gria4
|
UTSW |
9 |
4,513,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7501:Gria4
|
UTSW |
9 |
4,502,436 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7536:Gria4
|
UTSW |
9 |
4,464,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7604:Gria4
|
UTSW |
9 |
4,464,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Gria4
|
UTSW |
9 |
4,793,950 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7669:Gria4
|
UTSW |
9 |
4,462,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7703:Gria4
|
UTSW |
9 |
4,503,588 (GRCm39) |
missense |
probably benign |
|
|
R7720:Gria4
|
UTSW |
9 |
4,464,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Gria4
|
UTSW |
9 |
4,472,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7909:Gria4
|
UTSW |
9 |
4,464,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8007:Gria4
|
UTSW |
9 |
4,503,740 (GRCm39) |
splice site |
probably benign |
|
|
R8044:Gria4
|
UTSW |
9 |
4,456,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8062:Gria4
|
UTSW |
9 |
4,480,273 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R8131:Gria4
|
UTSW |
9 |
4,502,429 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8212:Gria4
|
UTSW |
9 |
4,480,242 (GRCm39) |
missense |
probably benign |
|
|
R8478:Gria4
|
UTSW |
9 |
4,793,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8699:Gria4
|
UTSW |
9 |
4,424,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8699:Gria4
|
UTSW |
9 |
4,424,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8785:Gria4
|
UTSW |
9 |
4,795,189 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8785:Gria4
|
UTSW |
9 |
4,456,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8888:Gria4
|
UTSW |
9 |
4,664,951 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8895:Gria4
|
UTSW |
9 |
4,664,951 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9160:Gria4
|
UTSW |
9 |
4,424,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9498:Gria4
|
UTSW |
9 |
4,503,560 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9743:Gria4
|
UTSW |
9 |
4,464,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0023:Gria4
|
UTSW |
9 |
4,427,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0065:Gria4
|
UTSW |
9 |
4,464,340 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCCGAGTCTGCATTTCCG -3'
(R):5'- GCCACGTTTTGTTGTAGCAAC -3'
Sequencing Primer
(F):5'- CGGAACTCATGCACTGGTTCTG -3'
(R):5'- GCAACAGAAATATCATAACACCTGG -3'
|
| Posted On |
2018-02-27 |
Incidental Mutation